BRPI0920756A2 - derivado de isoquinolinona - Google Patents
derivado de isoquinolinonaInfo
- Publication number
- BRPI0920756A2 BRPI0920756A2 BRPI0920756A BRPI0920756A BRPI0920756A2 BR PI0920756 A2 BRPI0920756 A2 BR PI0920756A2 BR PI0920756 A BRPI0920756 A BR PI0920756A BR PI0920756 A BRPI0920756 A BR PI0920756A BR PI0920756 A2 BRPI0920756 A2 BR PI0920756A2
- Authority
- BR
- Brazil
- Prior art keywords
- isoquinolinone derivative
- isoquinolinone
- derivative
- Prior art date
Links
- VDBNYAPERZTOOF-UHFFFAOYSA-N isoquinolin-1(2H)-one Chemical class C1=CC=C2C(=O)NC=CC2=C1 VDBNYAPERZTOOF-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Tropical Medicine & Parasitology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10176408P | 2008-10-01 | 2008-10-01 | |
| US17941709P | 2009-05-19 | 2009-05-19 | |
| PCT/SE2009/000432 WO2010039079A1 (en) | 2008-10-01 | 2009-10-01 | Isoquinolinone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0920756A2 true BRPI0920756A2 (pt) | 2019-09-24 |
Family
ID=42073703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0920756A BRPI0920756A2 (pt) | 2008-10-01 | 2009-10-01 | derivado de isoquinolinona |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8012980B2 (https=) |
| EP (1) | EP2344472A4 (https=) |
| JP (1) | JP2012504601A (https=) |
| KR (1) | KR20110067051A (https=) |
| CN (1) | CN102245593A (https=) |
| AR (1) | AR073711A1 (https=) |
| AU (1) | AU2009300456B2 (https=) |
| BR (1) | BRPI0920756A2 (https=) |
| CA (1) | CA2737434A1 (https=) |
| MX (1) | MX2011003489A (https=) |
| RU (1) | RU2512318C2 (https=) |
| TW (1) | TW201018665A (https=) |
| UY (1) | UY32154A (https=) |
| WO (1) | WO2010039079A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014520776A (ja) | 2011-07-04 | 2014-08-25 | バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー | 植物における非生物的ストレスに対する活性薬剤としての置換されているイソキノリノン類、イソキノリンジオン類、イソキノリントリオン類およびジヒドロイソキノリノン類または各場合でのそれらの塩の使用 |
| US12496297B1 (en) * | 2020-10-23 | 2025-12-16 | Washington University | Compositions of autophagy modulating agents and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU761453B2 (en) | 1999-03-17 | 2003-06-05 | Astrazeneca Ab | Amide derivatives |
| WO2003068750A1 (en) | 2002-02-13 | 2003-08-21 | Takeda Chemical Industries, Ltd. | Jnk inhibitor |
| JP2004143134A (ja) * | 2002-02-13 | 2004-05-20 | Takeda Chem Ind Ltd | Ｊｎｋ阻害剤 |
| US6867320B2 (en) * | 2002-02-21 | 2005-03-15 | Asahi Kasei Pharma Corporation | Substituted phenylalkanoic acid derivatives and use thereof |
| EP1487794A1 (en) | 2002-03-14 | 2004-12-22 | Bayer Aktiengesellschaft | Monocyclic aroylpyridinones as antiinflammatory agents |
| RU2297411C2 (ru) * | 2002-10-01 | 2007-04-20 | Мицубиси Фарма Корпорейшн | Изохинолиновые соединения, промежуточные соединения, способы их получения и применение |
| CA2535665A1 (en) | 2003-08-14 | 2005-02-24 | Asahi Kasei Pharma Corporation | Substituted arylalkanoic acid derivative and use thereof |
| JP2007008816A (ja) | 2003-10-15 | 2007-01-18 | Ube Ind Ltd | 新規イソキノリン誘導体 |
| NZ545694A (en) | 2003-12-03 | 2010-04-30 | Ym Bioscience Australia Pty Lt | Azole-based kinase inhibitors |
| GB0402812D0 (en) | 2004-02-09 | 2004-03-10 | Tanabe Seiyaku Co | Novel compounds |
| EP1763353A1 (en) | 2004-06-29 | 2007-03-21 | Warner-Lambert Company LLC | COMBINATION THERAPIES UTILIZING BENZAMIDE INHIBITORS OF THE P2X<sb>7</sb> RECEPTOR |
| US20070054916A1 (en) | 2004-10-01 | 2007-03-08 | Amgen Inc. | Aryl nitrogen-containing bicyclic compounds and methods of use |
| MY140868A (en) * | 2004-12-24 | 2010-01-29 | Astrazeneca Ab | Amide derivatives |
| GB0428326D0 (en) * | 2004-12-24 | 2005-02-02 | Astrazeneca Ab | Amide derivatives |
| RS52241B (sr) | 2005-07-26 | 2012-10-31 | Sanofi | Derivati cikloheksilamin izohinolona kao inhibitori rho-kinaze |
| EP2013175B9 (en) | 2006-05-04 | 2020-11-11 | Macrophage Pharma Limited | p38 MAP KINASE INHIBITORS |
| GB0608837D0 (en) | 2006-05-04 | 2006-06-14 | Chroma Therapeutics Ltd | Inhibitors of MAP kinase |
| TW200808771A (en) | 2006-05-08 | 2008-02-16 | Astrazeneca Ab | Novel compounds II |
| CL2008000973A1 (es) * | 2007-04-05 | 2009-01-02 | Astrazeneca Ab | Compuestos derivados de 1-oxo-isoquinolina; procedimiento de preparación; composición farmacéutica; y su uso en el tratamiento de enfermedades pulmonares obstructvas crónicas (epoc) y asma. |
| JP5140154B2 (ja) | 2007-06-27 | 2013-02-06 | アストラゼネカ・アクチエボラーグ | ピラジノン誘導体および肺疾患の処置におけるそれらの使用 |
-
2009
- 2009-09-29 AR ARP090103762A patent/AR073711A1/es unknown
- 2009-09-30 UY UY0001032154A patent/UY32154A/es unknown
- 2009-09-30 TW TW098133161A patent/TW201018665A/zh unknown
- 2009-10-01 BR BRPI0920756A patent/BRPI0920756A2/pt not_active IP Right Cessation
- 2009-10-01 KR KR1020117009801A patent/KR20110067051A/ko not_active Withdrawn
- 2009-10-01 EP EP09818051A patent/EP2344472A4/en not_active Withdrawn
- 2009-10-01 WO PCT/SE2009/000432 patent/WO2010039079A1/en not_active Ceased
- 2009-10-01 RU RU2011113437/04A patent/RU2512318C2/ru not_active IP Right Cessation
- 2009-10-01 AU AU2009300456A patent/AU2009300456B2/en not_active Ceased
- 2009-10-01 CA CA2737434A patent/CA2737434A1/en not_active Abandoned
- 2009-10-01 US US12/571,894 patent/US8012980B2/en not_active Expired - Fee Related
- 2009-10-01 JP JP2011530023A patent/JP2012504601A/ja not_active Ceased
- 2009-10-01 CN CN2009801481701A patent/CN102245593A/zh active Pending
- 2009-10-01 MX MX2011003489A patent/MX2011003489A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| RU2512318C2 (ru) | 2014-04-10 |
| RU2011113437A (ru) | 2012-11-10 |
| AR073711A1 (es) | 2010-11-24 |
| US8012980B2 (en) | 2011-09-06 |
| UY32154A (es) | 2010-04-30 |
| KR20110067051A (ko) | 2011-06-20 |
| JP2012504601A (ja) | 2012-02-23 |
| EP2344472A1 (en) | 2011-07-20 |
| TW201018665A (en) | 2010-05-16 |
| EP2344472A4 (en) | 2012-11-28 |
| CA2737434A1 (en) | 2010-04-08 |
| CN102245593A (zh) | 2011-11-16 |
| MX2011003489A (es) | 2011-05-02 |
| WO2010039079A1 (en) | 2010-04-08 |
| AU2009300456A1 (en) | 2010-04-08 |
| US20100099665A1 (en) | 2010-04-22 |
| AU2009300456B2 (en) | 2012-04-12 |
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