BRPI0918959A2 - proteínas recombinantes tendo atividade hemostática e capazes de induzir agregação plaquetária - Google Patents

proteínas recombinantes tendo atividade hemostática e capazes de induzir agregação plaquetária

Info

Publication number
BRPI0918959A2
BRPI0918959A2 BRPI0918959A BRPI0918959A BRPI0918959A2 BR PI0918959 A2 BRPI0918959 A2 BR PI0918959A2 BR PI0918959 A BRPI0918959 A BR PI0918959A BR PI0918959 A BRPI0918959 A BR PI0918959A BR PI0918959 A2 BRPI0918959 A2 BR PI0918959A2
Authority
BR
Brazil
Prior art keywords
platelet aggregation
recombinant proteins
hemostatic activity
inducing platelet
inducing
Prior art date
Application number
BRPI0918959A
Other languages
English (en)
Inventor
David Vandroux
Edourd Prost
Emmanuel De Maistre
Original Assignee
Ct Hospitalier Universitaire De Dijon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Hospitalier Universitaire De Dijon filed Critical Ct Hospitalier Universitaire De Dijon
Publication of BRPI0918959A2 publication Critical patent/BRPI0918959A2/pt
Publication of BRPI0918959B1 publication Critical patent/BRPI0918959B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
BRPI0918959-9A 2008-09-24 2009-09-22 Proteínas recombinantes tendo atividade hemostática e capazes de induzir agregação plaquetária BRPI0918959B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0856423 2008-09-24
FR0856423A FR2936247B1 (fr) 2008-09-24 2008-09-24 Proteines recombinantes a activite hemostatique capables d'induire l'agregation plaquettaire.
PCT/EP2009/062271 WO2010034718A1 (fr) 2008-09-24 2009-09-22 Proteines recombinantes a activite hemostatique capables d'induire l'agregation plaquett aire

Publications (2)

Publication Number Publication Date
BRPI0918959A2 true BRPI0918959A2 (pt) 2015-12-01
BRPI0918959B1 BRPI0918959B1 (pt) 2021-07-27

Family

ID=40613031

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0918959-9A BRPI0918959B1 (pt) 2008-09-24 2009-09-22 Proteínas recombinantes tendo atividade hemostática e capazes de induzir agregação plaquetária

Country Status (14)

Country Link
US (2) US8557774B2 (pt)
EP (1) EP2337796B1 (pt)
JP (1) JP5675620B2 (pt)
KR (1) KR101700970B1 (pt)
CN (1) CN102224167B (pt)
AU (1) AU2009295917B2 (pt)
BR (1) BRPI0918959B1 (pt)
CA (1) CA2738209C (pt)
DK (1) DK2337796T3 (pt)
ES (1) ES2419657T3 (pt)
FR (1) FR2936247B1 (pt)
IL (1) IL211740A (pt)
WO (1) WO2010034718A1 (pt)
ZA (1) ZA201101989B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE044239T2 (hu) 2008-03-27 2019-10-28 Purdue Research Foundation Kollagén-kötõ szintetikus peptidoglikánok, elõállításuk és alkalmazási eljárásaik
FR2936247B1 (fr) * 2008-09-24 2010-10-22 Ct Hospitalier Universitaire De Dijon Proteines recombinantes a activite hemostatique capables d'induire l'agregation plaquettaire.
WO2010129547A1 (en) * 2009-05-04 2010-11-11 Purdue Research Foundation Collagen-binding synthetic peptidoglycans for wound healing
WO2011163492A1 (en) * 2010-06-23 2011-12-29 Purdue Research Foundation Collagen-binding synthetic peptidoglycans for use in vascular intervention
JP5747493B2 (ja) * 2010-12-13 2015-07-15 Jnc株式会社 血小板放出促進剤および血小板放出促進方法
KR102006036B1 (ko) 2011-05-24 2019-07-31 시믹 아이피, 엘엘씨 히알루론산-결합 합성 펩티도글리칸 및 이의 제조 및 이용 방법
FR2997083B1 (fr) 2012-10-19 2014-12-12 Nvh Medicinal Proteines recombinantes derivees du collagene a activite de liaison au facteur willebrand
SG11201506966RA (en) 2013-03-15 2015-10-29 Symic Biomedical Inc Extracellular matrix-binding synthetic peptidoglycans
FR3014319B1 (fr) * 2013-12-11 2016-12-09 Nvh Medicinal Preparations injectables a base de collagenes capables de controler les saignements et/ou de se substituer a des plaquettes dans le cas de syndromes hemorragiques
WO2015164822A1 (en) 2014-04-25 2015-10-29 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
CA2995310A1 (en) 2015-08-25 2017-03-02 Histide Ag Compounds for inducing tissue formation and uses thereof
US11529424B2 (en) 2017-07-07 2022-12-20 Symic Holdings, Inc. Synthetic bioconjugates
CN108503692B (zh) * 2017-07-10 2019-12-31 昆明医科大学第一附属医院 一种促血小板聚集的多肽pep1
CN108570095B (zh) * 2017-07-10 2019-12-31 昆明医科大学第一附属医院 一种促血小板聚集的多肽site2
CN108503694B (zh) * 2017-07-10 2019-12-24 昆明医科大学第一附属医院 一种促血小板聚集的多肽8496
CN108503693B (zh) * 2017-07-10 2019-12-31 昆明医科大学第一附属医院 一种促血小板聚集的多肽km17
CN107653244B (zh) * 2017-11-30 2020-06-02 海默斯（重庆）医学生物技术有限公司 一种止血蛋白及其制备方法和应用
CN109456989B (zh) * 2018-10-31 2022-03-29 陕西慧康生物科技有限责任公司 一种提高毕赤酵母分泌表达的载体的构建方法
FR3112942A1 (fr) 2020-08-03 2022-02-04 Nvh Medicinal Ligands protéiques immunomodulateurs dérivés du collagène utilisables par voie injectable

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2399371A1 (en) * 1999-11-12 2001-05-17 Fibrogen, Inc. Animal collagens and gelatins
EP1232182B1 (en) * 1999-11-12 2007-10-03 Fibrogen, Inc. Bovine collagen and method for producing recombinant gelatin
US20040151731A1 (en) * 2003-02-04 2004-08-05 Jicha Douglas L. Methods and compositions involving T-lymphocyte reactivity with collagen in aortic tissue of abdominal aortic aneurysm patients
EP1845107B1 (en) * 2003-03-28 2019-05-29 FUJIFILM Manufacturing Europe B.V. Drug delivery system comprising RGD-enriched gelatine-like proteins with enhanced cell binding
JP2005058499A (ja) * 2003-08-13 2005-03-10 Masao Tanihara 生体材料
FR2936247B1 (fr) * 2008-09-24 2010-10-22 Ct Hospitalier Universitaire De Dijon Proteines recombinantes a activite hemostatique capables d'induire l'agregation plaquettaire.

Also Published As

Publication number Publication date
IL211740A (en) 2014-12-31
CN102224167A (zh) 2011-10-19
CA2738209A1 (en) 2010-04-01
FR2936247B1 (fr) 2010-10-22
US20110207669A1 (en) 2011-08-25
US8557774B2 (en) 2013-10-15
KR20110069020A (ko) 2011-06-22
DK2337796T3 (da) 2013-07-15
AU2009295917A1 (en) 2010-04-01
IL211740A0 (en) 2011-06-30
JP5675620B2 (ja) 2015-02-25
JP2012503481A (ja) 2012-02-09
ZA201101989B (en) 2012-01-25
ES2419657T3 (es) 2013-08-21
WO2010034718A8 (fr) 2010-12-23
BRPI0918959B1 (pt) 2021-07-27
EP2337796A1 (fr) 2011-06-29
FR2936247A1 (fr) 2010-03-26
EP2337796B1 (fr) 2013-04-17
CA2738209C (en) 2018-02-20
US9115183B2 (en) 2015-08-25
WO2010034718A1 (fr) 2010-04-01
AU2009295917B2 (en) 2014-02-06
CN102224167B (zh) 2014-04-02
US20130260456A1 (en) 2013-10-03
KR101700970B1 (ko) 2017-01-31

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/09/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.