BRPI0915946A2 - material de sol de silíca com pelo menos uma substância teurapeuticamente ativa para a preparação de materiais de gel de sílica biologicamente degradáveis e/ou reabsrovíveis para a medicina e/ou tecnologia médica - Google Patents

material de sol de silíca com pelo menos uma substância teurapeuticamente ativa para a preparação de materiais de gel de sílica biologicamente degradáveis e/ou reabsrovíveis para a medicina e/ou tecnologia médica

Info

Publication number
BRPI0915946A2
BRPI0915946A2 BRPI0915946-0A BRPI0915946A BRPI0915946A2 BR PI0915946 A2 BRPI0915946 A2 BR PI0915946A2 BR PI0915946 A BRPI0915946 A BR PI0915946A BR PI0915946 A2 BRPI0915946 A2 BR PI0915946A2
Authority
BR
Brazil
Prior art keywords
preparation
active substance
therapeutically active
resorbable
medical technology
Prior art date
Application number
BRPI0915946-0A
Other languages
English (en)
Inventor
Baecker Iwer
Rothenburger Glaubitt Miranda
Probst Jorn
Egger Holger
Original Assignee
Bayer Innovation Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Innovation Gmbh filed Critical Bayer Innovation Gmbh
Publication of BRPI0915946A2 publication Critical patent/BRPI0915946A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/64—Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/62227—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products obtaining fibres
    • C04B35/62231—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products obtaining fibres based on oxide ceramics
    • C04B35/6224—Fibres based on silica
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/06—Preparatory processes
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
    • C04B2235/30—Constituents and secondary phases not being of a fibrous nature
    • C04B2235/40—Metallic constituents or additives not added as binding phase
    • C04B2235/408—Noble metals
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
    • C04B2235/30—Constituents and secondary phases not being of a fibrous nature
    • C04B2235/44—Metal salt constituents or additives chosen for the nature of the anions, e.g. hydrides or acetylacetonate
    • C04B2235/441—Alkoxides, e.g. methoxide, tert-butoxide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Cell Biology (AREA)
  • Structural Engineering (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Polymers & Plastics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silicon Compounds (AREA)
  • Silicon Polymers (AREA)
  • Inorganic Fibers (AREA)

Abstract

material de sol de sílica com pelo menos uma substância terapeuticamente ativa para preparação de materiais de sílica-gel biologicamente degradáveis e/ou reabsorvíveis para a medicina humana e/ou tecnologia médica a presente invenção refere-se a um novo material de sol de sílica com pelo menos uma substância terapeuticamente ativa e ao seu uso para preparação de materiais de sílica-gel biologicamente reabsorvíveis e/ou biologicamente degradáveis com propriedades aperfeiçoadas. os materiais como, por exemplo, fibras, tecido não tecido, pós, monólito e/ou revestimentos são empregados, por exemplo, na tecnologia médica e/ou na medicina humana, particularmente para o tratamento de feridas.
BRPI0915946-0A 2008-07-16 2009-07-03 material de sol de silíca com pelo menos uma substância teurapeuticamente ativa para a preparação de materiais de gel de sílica biologicamente degradáveis e/ou reabsrovíveis para a medicina e/ou tecnologia médica BRPI0915946A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008033327.1 2008-07-16
DE102008033327A DE102008033327A1 (de) 2008-07-16 2008-07-16 Kieselsol-Material mit mindestens einem therapeutisch aktiven Wirkstoff zur Herstellung von biologisch degradierbaren und/oder resorbierbaren Kieselgel-Materialien für die Humanmedizin und/oder Medizintechnik
PCT/EP2009/004806 WO2010006708A1 (de) 2008-07-16 2009-07-03 Kieselsol-material mit mindestens einem therapeutisch aktiven wirkstoff zur herstellung von biologisch degradierbaren und/oder resorbierbaren kieselgel-materialen für die humanmedizin und/oder medizintechnik

Publications (1)

Publication Number Publication Date
BRPI0915946A2 true BRPI0915946A2 (pt) 2019-04-09

Family

ID=41011815

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0915946-0A BRPI0915946A2 (pt) 2008-07-16 2009-07-03 material de sol de silíca com pelo menos uma substância teurapeuticamente ativa para a preparação de materiais de gel de sílica biologicamente degradáveis e/ou reabsrovíveis para a medicina e/ou tecnologia médica

Country Status (13)

Country Link
US (1) US20110123596A1 (pt)
EP (1) EP2303948B1 (pt)
JP (1) JP2011527913A (pt)
KR (1) KR20110039533A (pt)
CN (1) CN102159623A (pt)
AU (1) AU2009270515A1 (pt)
BR (1) BRPI0915946A2 (pt)
CA (1) CA2730697C (pt)
DE (1) DE102008033327A1 (pt)
IL (1) IL210313A0 (pt)
MX (1) MX2011000475A (pt)
RU (1) RU2512512C2 (pt)
WO (1) WO2010006708A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010008981A1 (de) * 2010-02-24 2011-08-25 Bayer Innovation GmbH, 40225 Siliciumhaltiges, biologisch degradierbares Material zur pro-angiogenetischen Therapie
DE102010008982A1 (de) * 2010-02-24 2011-08-25 Bayer Innovation GmbH, 40225 Siliciumhaltiges, biologisch degradierbares Material zur anti-inflammatorischen Therapie
DE102010023336A1 (de) * 2010-06-10 2011-12-15 Bayer Innovation Gmbh Verfahren zur Herstellung eines Kieselsol-Materials
BR112012033600A2 (pt) * 2010-07-02 2016-11-29 Procter & Gamble Comapny filamentos compreendendo mantas de não-tecido com agente ingerível e métodos de fabricação dos mesmos.
EP2588655B1 (en) 2010-07-02 2017-11-15 The Procter and Gamble Company Method for delivering an active agent
RU2541949C2 (ru) 2010-07-02 2015-02-20 Дзе Проктер Энд Гэмбл Компани Филаменты, содержащие активный агент, нетканые полотна и способы их получения
WO2012003351A2 (en) 2010-07-02 2012-01-05 The Procter & Gamble Company Web material and method for making same
CA2830654A1 (en) * 2011-03-31 2012-10-04 Galderma Research & Development Compositions comprising a filler product and at least one bioresorbable and biodegradable silica-based material
FI20155779A (fi) * 2015-10-30 2017-05-01 Solani Therapeutics Ltd Ei-steroidaalisen anti-inflammatorisen lääkkeen hidastetusti vapautuva annostelu
JP6882519B2 (ja) 2017-01-27 2021-06-02 ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ 発泡性凝集粒子を含む溶解性固形構造体形態の組成物
DE102017009989A1 (de) * 2017-10-26 2019-05-02 Carl Freudenberg Kg Biokompatibles Verbundmaterial zum Einbringen in einen menschlichen Körper
US20190255223A1 (en) * 2018-02-16 2019-08-22 American Nano, LLC Silica fiber compositions and methods of use
CN108283707B (zh) * 2018-04-05 2021-03-26 广西中医药大学 一种瑶药退烧贴及其制备方法
US11666514B2 (en) 2018-09-21 2023-06-06 The Procter & Gamble Company Fibrous structures containing polymer matrix particles with perfume ingredients
US11679066B2 (en) 2019-06-28 2023-06-20 The Procter & Gamble Company Dissolvable solid fibrous articles containing anionic surfactants
MX2023001042A (es) 2020-07-31 2023-02-16 Procter & Gamble Bolsa fibrosa soluble en agua que contiene granulos para el cuidado del cabello.
CN113332488A (zh) * 2021-05-31 2021-09-03 南昌智产科技有限公司 一种医用硅凝胶泡沫敷料及其制备方法
CN114404660A (zh) * 2022-01-21 2022-04-29 江苏信立康医疗科技有限公司 一种基于三维支架的细胞培养方法
CN115531592A (zh) * 2022-10-27 2022-12-30 李升红 一种实现皮肤高效修复的皮肤敷料及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19609551C1 (de) 1996-03-12 1997-07-17 Fraunhofer Ges Forschung Biologisch degradierbare und/oder biologisch resorbierbare (Endlos)Fasern, Verfahren zu deren Herstellung und deren Verwendung als Verstärkungsfasern
US6764690B2 (en) * 1996-05-29 2004-07-20 Delsitech Oy Dissolvable oxides for biological applications
SK284193B6 (sk) * 1996-05-29 2004-10-05 Delsitech Oy Prostriedok na podávanie biologicky účinnej látky, zabezpečujúci jej pomalé uvoľňovanie, jeho použitie a farmaceutický prostriedok s jeho obsahom
WO2000047236A1 (en) * 1999-02-12 2000-08-17 Biostream, Inc. Matrices for drug delivery and methods for making and using the same
ES2290013T3 (es) * 1999-02-22 2008-02-16 Delsitech Oy Fibras de ceramica biodegradables procedentes de soles de silice.
US7118921B1 (en) * 1999-06-24 2006-10-10 Mcmaster University Incorporation and applications of biomolecular interactions within a carrier
JP2003503423A (ja) * 1999-06-24 2003-01-28 マクマスター ユニヴァーシティー キャリア内の生体分子相互作用の取込みおよび適用
DE10126137C1 (de) * 2001-05-29 2002-11-07 Andreas Haisch Verfahren zur Herstellung von Zellen, Geweben und Organen
DE102004063599B4 (de) 2004-12-30 2007-07-12 Bayer Innovation Gmbh Verkürzte Wundheilungsprozesse mittels neuartiger Faservliese
DE102007061873A1 (de) * 2007-01-15 2008-07-17 Bayer Innovation Gmbh Kieselsol-Material zur Herstellung von biologisch degradierbaren und/oder resorbierbaren Kieselgel-Materialien dessen Herstellung und Verwendung
ATE535548T1 (de) * 2007-01-16 2011-12-15 Basf Se Verfahren zur herstellung von polymerpartikeln durch polymerisation von flüssigkeitstropfen in einer gasphase

Also Published As

Publication number Publication date
EP2303948A1 (de) 2011-04-06
EP2303948B1 (de) 2018-09-12
RU2512512C2 (ru) 2014-04-10
MX2011000475A (es) 2011-03-15
AU2009270515A1 (en) 2010-01-21
CA2730697A1 (en) 2010-01-21
CN102159623A (zh) 2011-08-17
RU2011105299A (ru) 2012-08-27
WO2010006708A1 (de) 2010-01-21
DE102008033327A1 (de) 2010-01-21
JP2011527913A (ja) 2011-11-10
CA2730697C (en) 2016-10-25
US20110123596A1 (en) 2011-05-26
KR20110039533A (ko) 2011-04-19
IL210313A0 (en) 2011-03-31

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