BRPI0914925A2 - peptídeo cíclico, uso de um peptídeo, métodos para produzir um peptídeo cíclico e para diagnosticar uma doença ou condição, e, anticorpo - Google Patents
peptídeo cíclico, uso de um peptídeo, métodos para produzir um peptídeo cíclico e para diagnosticar uma doença ou condição, e, anticorpoInfo
- Publication number
- BRPI0914925A2 BRPI0914925A2 BRPI0914925A BRPI0914925A BRPI0914925A2 BR PI0914925 A2 BRPI0914925 A2 BR PI0914925A2 BR PI0914925 A BRPI0914925 A BR PI0914925A BR PI0914925 A BRPI0914925 A BR PI0914925A BR PI0914925 A2 BRPI0914925 A2 BR PI0914925A2
- Authority
- BR
- Brazil
- Prior art keywords
- peptide
- cyclic peptide
- diagnosing
- antibody
- disease
- Prior art date
Links
- 108010069514 Cyclic Peptides Proteins 0.000 title 2
- 102000001189 Cyclic Peptides Human genes 0.000 title 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1716—Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Marine Sciences & Fisheries (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7726408P | 2008-07-01 | 2008-07-01 | |
EP08159385 | 2008-07-01 | ||
PCT/NL2009/050387 WO2010002251A1 (en) | 2008-07-01 | 2009-07-01 | Vaccine against amyloid folding intermediate |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0914925A2 true BRPI0914925A2 (pt) | 2015-10-20 |
Family
ID=39944379
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0914925A BRPI0914925A2 (pt) | 2008-07-01 | 2009-07-01 | peptídeo cíclico, uso de um peptídeo, métodos para produzir um peptídeo cíclico e para diagnosticar uma doença ou condição, e, anticorpo |
Country Status (14)
Country | Link |
---|---|
US (1) | US9045555B2 (pt) |
EP (1) | EP2297196B1 (pt) |
JP (1) | JP5722770B2 (pt) |
KR (1) | KR101694788B1 (pt) |
CN (1) | CN102112488A (pt) |
AU (1) | AU2009266552B2 (pt) |
BR (1) | BRPI0914925A2 (pt) |
CA (1) | CA2729414C (pt) |
ES (1) | ES2397641T3 (pt) |
IL (1) | IL210364A (pt) |
MX (1) | MX2011000134A (pt) |
NZ (1) | NZ590324A (pt) |
RU (1) | RU2546234C2 (pt) |
WO (1) | WO2010002251A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3056510B1 (en) * | 2010-03-03 | 2018-10-03 | The University Of British Columbia | Oligomer-specific amyloid beta epitope and antibodies |
AU2013205000B2 (en) * | 2010-03-03 | 2015-05-28 | The University Of British Columbia | Oligomer-specific amyloid beta epitope and antibodies |
WO2012072611A1 (de) * | 2010-11-29 | 2012-06-07 | Philipps-Universität Marburg | SYNTHETISCHE LIGANDEN FÜR HUMANE ANTI-Aβ-ANTIKÖRPER |
TWI571207B (zh) | 2011-06-26 | 2017-02-21 | 安麗托克斯公司 | 用於條件化動物飼料之寒冷天氣調配物 |
EA201491851A1 (ru) * | 2011-11-10 | 2015-12-30 | Канджин Ю.С., Инкорпорейтед | Композиции и способы для лечения болезни альцгеймера |
WO2015017280A1 (en) | 2013-07-28 | 2015-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
WO2017079835A1 (en) | 2015-11-09 | 2017-05-18 | The University Of British Columbia | Amyloid beta epitopes and antibodies thereto |
JP2019507581A (ja) * | 2015-11-09 | 2019-03-22 | ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア | アミロイドベータのエピトープおよびそれに対する立体配座選択的抗体 |
EP3374380A4 (en) * | 2015-11-09 | 2019-05-15 | The University Of British Columbia | C-TERMINAL EPITOPES IN BETA-AMYLOID AND RELATED CONFORMATIONAL ANTIBODIES |
CN108350051A (zh) * | 2015-11-09 | 2018-07-31 | 英属哥伦比亚大学 | 淀粉样蛋白β中的N-末端表位及其构象选择性抗体 |
KR20180085736A (ko) * | 2015-11-09 | 2018-07-27 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 아밀로이드 베타 중간-영역 내 에피토프 및 이에 대해 구조적으로 선택성인 항체 |
US20180125920A1 (en) | 2016-11-09 | 2018-05-10 | The University Of British Columbia | Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions |
US20230051538A1 (en) * | 2018-10-07 | 2023-02-16 | The University Of British Columbia | Conformation-specific epitopes in alpha-synuclein, antibodies thereto and methods related thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003534351A (ja) * | 2000-05-22 | 2003-11-18 | ニュー・ヨーク・ユニヴァーシティー | アミロイドβ及びアミロイド沈着物に対する免疫応答誘導のための、アミロイドβと相同的な、合成の、免疫原性だが非アミロイド原性ペプチド |
DE10101430B4 (de) * | 2001-01-13 | 2008-10-02 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Lösliche cyclische Analoga zur Modulation der Amyloidogenese |
DK1524994T3 (da) * | 2002-07-19 | 2011-08-15 | Cytos Biotechnology Ag | Vaccinesammensætninger indeholdende amyloid beta 1-6-antigen-arrays |
PL210065B1 (pl) * | 2002-09-25 | 2011-11-30 | Memory Pharm Corp | Związki indazole, benzotiazole i benzoizotiazole, kompozycje farmaceutyczne je zawierające oraz zastosowanie związków |
CN100409896C (zh) * | 2003-03-31 | 2008-08-13 | 姚志彬 | 一种老年性痴呆疫苗及其制备方法 |
EP1676859A1 (en) * | 2004-12-30 | 2006-07-05 | Pevion Biotech Ltd. | Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide |
MX2007013825A (es) * | 2005-05-05 | 2008-01-18 | Merck & Co Inc | Composiciones de un conjugado peptidico y metodos para la prevencion y tratamiento de la enfermedad de alzheimer. |
US20110092445A1 (en) * | 2008-07-25 | 2011-04-21 | Abbott Laboratories | Amyloid ß peptide analogues, oligomers thereof, processes for preparing and composi-tions comprising said analogues or oligomers, and their uses |
-
2009
- 2009-07-01 BR BRPI0914925A patent/BRPI0914925A2/pt not_active Application Discontinuation
- 2009-07-01 MX MX2011000134A patent/MX2011000134A/es active IP Right Grant
- 2009-07-01 CN CN2009801306774A patent/CN102112488A/zh active Pending
- 2009-07-01 AU AU2009266552A patent/AU2009266552B2/en not_active Ceased
- 2009-07-01 CA CA2729414A patent/CA2729414C/en not_active Expired - Fee Related
- 2009-07-01 ES ES09773784T patent/ES2397641T3/es active Active
- 2009-07-01 KR KR1020117002526A patent/KR101694788B1/ko active IP Right Grant
- 2009-07-01 RU RU2011103448/10A patent/RU2546234C2/ru not_active IP Right Cessation
- 2009-07-01 WO PCT/NL2009/050387 patent/WO2010002251A1/en active Application Filing
- 2009-07-01 NZ NZ590324A patent/NZ590324A/xx not_active IP Right Cessation
- 2009-07-01 US US13/002,174 patent/US9045555B2/en not_active Expired - Fee Related
- 2009-07-01 EP EP09773784A patent/EP2297196B1/en not_active Not-in-force
- 2009-07-01 JP JP2011516186A patent/JP5722770B2/ja not_active Expired - Fee Related
-
2010
- 2010-12-29 IL IL210364A patent/IL210364A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2009266552A1 (en) | 2010-01-07 |
IL210364A (en) | 2016-09-29 |
MX2011000134A (es) | 2011-04-05 |
JP5722770B2 (ja) | 2015-05-27 |
CA2729414C (en) | 2017-08-22 |
ES2397641T3 (es) | 2013-03-08 |
IL210364A0 (en) | 2011-03-31 |
US20110182928A1 (en) | 2011-07-28 |
CN102112488A (zh) | 2011-06-29 |
AU2009266552B2 (en) | 2014-01-23 |
CA2729414A1 (en) | 2010-01-07 |
EP2297196B1 (en) | 2012-11-14 |
WO2010002251A1 (en) | 2010-01-07 |
KR101694788B1 (ko) | 2017-01-13 |
RU2011103448A (ru) | 2012-08-10 |
RU2546234C2 (ru) | 2015-04-10 |
EP2297196A1 (en) | 2011-03-23 |
KR20110043635A (ko) | 2011-04-27 |
NZ590324A (en) | 2012-08-31 |
JP2011526885A (ja) | 2011-10-20 |
US9045555B2 (en) | 2015-06-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |