BRPI0914300A2 - composições e métodos para imunogenicidade intensificada de somatostatina - Google Patents
composições e métodos para imunogenicidade intensificada de somatostatinaInfo
- Publication number
- BRPI0914300A2 BRPI0914300A2 BRPI0914300A BRPI0914300A BRPI0914300A2 BR PI0914300 A2 BRPI0914300 A2 BR PI0914300A2 BR PI0914300 A BRPI0914300 A BR PI0914300A BR PI0914300 A BRPI0914300 A BR PI0914300A BR PI0914300 A2 BRPI0914300 A2 BR PI0914300A2
- Authority
- BR
- Brazil
- Prior art keywords
- somatostatin
- compositions
- methods
- enhanced immunogenicity
- immunogenicity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12N9/1033—Chloramphenicol O-acetyltransferase (2.3.1.28)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7565608P | 2008-06-25 | 2008-06-25 | |
| US61/075,656 | 2008-06-25 | ||
| PCT/US2009/048429 WO2009158395A1 (en) | 2008-06-25 | 2009-06-24 | Compositions and methods for enhanced somatostatin immunogenicity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0914300A2 true BRPI0914300A2 (pt) | 2015-10-13 |
| BRPI0914300B1 BRPI0914300B1 (pt) | 2021-03-23 |
| BRPI0914300B8 BRPI0914300B8 (pt) | 2021-05-25 |
Family
ID=41444916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0914300A BRPI0914300B8 (pt) | 2008-06-25 | 2009-06-24 | vacina para tratamento de obesidade |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8425914B2 (pt) |
| EP (1) | EP2291194B1 (pt) |
| JP (1) | JP5627581B2 (pt) |
| KR (1) | KR101627879B1 (pt) |
| CN (1) | CN102119033B (pt) |
| AU (1) | AU2009262243B2 (pt) |
| BR (1) | BRPI0914300B8 (pt) |
| CA (1) | CA2728735A1 (pt) |
| CO (1) | CO6321162A2 (pt) |
| IL (1) | IL209829A (pt) |
| MX (1) | MX2010014078A (pt) |
| NZ (1) | NZ590010A (pt) |
| RU (1) | RU2519051C2 (pt) |
| WO (1) | WO2009158395A1 (pt) |
| ZA (1) | ZA201009127B (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008121767A2 (en) | 2007-03-28 | 2008-10-09 | President And Fellows Of Harvard College | Stitched polypeptides |
| CA2728734A1 (en) | 2008-06-25 | 2009-12-30 | Braasch Biotech Llc | Chloramphenicol acetyl transferase (cat)-defective somatostatin fusion protein and uses thereof |
| EP2291194B1 (en) | 2008-06-25 | 2017-02-22 | Braasch Biotech LLC | Compositions and methods for enhanced somatostatin immunogenicity |
| EP2327411A1 (en) * | 2009-11-27 | 2011-06-01 | Lonza Ltd. | Arabinogalactan as immune enhancer |
| US8784844B2 (en) | 2009-09-30 | 2014-07-22 | Lonza Ltd. | Arabinogalactan for enhancing the adaptive immune response |
| JP6181121B2 (ja) * | 2009-09-30 | 2017-08-16 | ロンザ リミテッドＬｏｎｚａ Ｌｉｍｉｔｅｄ | 適応性免疫応答を向上させるためのアラビノガラクタン |
| RU2582678C2 (ru) | 2010-08-13 | 2016-04-27 | Эйлерон Терапьютикс, Инк. | Пептидомиметические макроциклы |
| TWI643868B (zh) | 2011-10-18 | 2018-12-11 | 艾利倫治療公司 | 擬肽巨環化合物 |
| JP6450191B2 (ja) | 2012-02-15 | 2019-01-09 | エイルロン セラピューティクス，インコーポレイテッド | ペプチドミメティック大環状化合物 |
| EP2819688A4 (en) | 2012-02-15 | 2015-10-28 | Aileron Therapeutics Inc | TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES |
| WO2014071241A1 (en) | 2012-11-01 | 2014-05-08 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
| US9393259B2 (en) | 2013-03-21 | 2016-07-19 | Lonza Ltd. | Composition comprising arabinogalactan and polyphenols from larch trees |
| WO2016029013A2 (en) | 2014-08-21 | 2016-02-25 | Braasch Biotech Llc | Methods for improving immunological response in vaccinated animals |
| KR20170058424A (ko) | 2014-09-24 | 2017-05-26 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방 거대고리 및 이의 용도 |
| JP2018516844A (ja) | 2015-03-20 | 2018-06-28 | エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | ペプチド模倣大環状分子およびその使用 |
| JP2019534707A (ja) * | 2016-08-26 | 2019-12-05 | エヌエーエル ファーマシューティカル グループ リミティド | アルブミン及びその類似体の融合タンパク質を含有する組成物、前記組成物を製造及び使用するための方法 |
| RU2722849C1 (ru) | 2019-12-25 | 2020-06-04 | Владимир Глебович Лунин | Рекомбинантный белок GBD-SSTad-SSTad, способ его получения и применения |
| RU2766292C1 (ru) * | 2021-08-05 | 2022-03-14 | Федеральное государственное унитарное предприятие "Санкт-Петербургский научно-исследовательский институт вакцин и сывороток и предприятие по производству бактерийных препаратов" Федерального медико-биологического агентства (ФГУП СПбНИИВС ФМБА России) | Состав вакцины против covid-19 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3919411A (en) * | 1972-01-31 | 1975-11-11 | Bayvet Corp | Injectable adjuvant and compositions including such adjuvant |
| US4342832A (en) | 1979-07-05 | 1982-08-03 | Genentech, Inc. | Method of constructing a replicable cloning vehicle having quasi-synthetic genes |
| US4446235A (en) | 1982-03-22 | 1984-05-01 | Genentech, Inc. | Method for cloning human growth hormone varient genes |
| AU625394B2 (en) | 1987-11-04 | 1992-07-09 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Alveolar surfactant proteins |
| US6316004B1 (en) * | 1993-06-22 | 2001-11-13 | T. Tikhonenko | Chimeric somatostatin containing protein and encoding DNA, plasmids of expression, method for preparing chimeric protein, strain-producers, immunogenic composition, method for increasing the productivity of farm animals |
| AUPN999096A0 (en) * | 1996-05-22 | 1996-06-13 | Northstar Biologicals Pty Ltd | Peptides, antibodies, vaccines & uses thereof |
| US6303584B1 (en) * | 1996-11-20 | 2001-10-16 | The University Of Montana | Water soluble lipidated arabinogalactan |
| US6025368A (en) | 1997-02-25 | 2000-02-15 | Celtrix Pharmaceuticals, Inc. | Method for treating the symptoms of chronic stress-related disorders using IGF |
| US20070048860A1 (en) * | 1997-10-10 | 2007-03-01 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Carcinoembryonic antigen (CEA) peptides |
| WO1999066950A1 (en) * | 1998-06-20 | 1999-12-29 | United Biomedical Inc. | Synthetic somatostatin immunogen for growth promotion in farm animals |
| US7018638B2 (en) * | 2000-12-19 | 2006-03-28 | Wyeth | Mycoplasma hyopneumoniae bacterin vaccine |
| MY129765A (en) * | 2000-12-19 | 2007-04-30 | Wyeth Corp | Improved mycoplasma hyopneumoniae bacterin vaccine |
| ITMI20010571A1 (it) * | 2001-03-19 | 2002-09-19 | Grisotech S A | Vaccini assorbibili per via trans-mucosale |
| US6861410B1 (en) * | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
| PL213561B1 (pl) | 2004-01-09 | 2013-03-29 | Inst Biotechnologii I Antybiotykow | Sposób otrzymywania plazmidu, plazmid oraz zastosowania |
| US7998930B2 (en) | 2004-11-04 | 2011-08-16 | Hanall Biopharma Co., Ltd. | Modified growth hormones |
| US7833707B2 (en) * | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
| WO2007002597A2 (en) | 2005-06-27 | 2007-01-04 | Biovail Laboratories International S.R.L. | Modified-release formulations of a bupropion salt |
| GB0622282D0 (en) * | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
| EP2291194B1 (en) | 2008-06-25 | 2017-02-22 | Braasch Biotech LLC | Compositions and methods for enhanced somatostatin immunogenicity |
| CA2728734A1 (en) | 2008-06-25 | 2009-12-30 | Braasch Biotech Llc | Chloramphenicol acetyl transferase (cat)-defective somatostatin fusion protein and uses thereof |
-
2009
- 2009-06-24 EP EP09770928.1A patent/EP2291194B1/en not_active Not-in-force
- 2009-06-24 JP JP2011516577A patent/JP5627581B2/ja active Active
- 2009-06-24 WO PCT/US2009/048429 patent/WO2009158395A1/en active Application Filing
- 2009-06-24 US US12/523,952 patent/US8425914B2/en active Active
- 2009-06-24 NZ NZ590010A patent/NZ590010A/xx not_active IP Right Cessation
- 2009-06-24 CA CA2728735A patent/CA2728735A1/en not_active Abandoned
- 2009-06-24 CN CN200980131325.0A patent/CN102119033B/zh active Active
- 2009-06-24 MX MX2010014078A patent/MX2010014078A/es active IP Right Grant
- 2009-06-24 KR KR1020107029178A patent/KR101627879B1/ko active IP Right Grant
- 2009-06-24 RU RU2011100105/15A patent/RU2519051C2/ru active
- 2009-06-24 AU AU2009262243A patent/AU2009262243B2/en not_active Ceased
- 2009-06-24 BR BRPI0914300A patent/BRPI0914300B8/pt active IP Right Grant
-
2010
- 2010-12-07 IL IL209829A patent/IL209829A/en active IP Right Grant
- 2010-12-20 ZA ZA2010/09127A patent/ZA201009127B/en unknown
- 2010-12-22 CO CO10160849A patent/CO6321162A2/es not_active Application Discontinuation
-
2013
- 2013-02-19 US US13/770,118 patent/US20130149332A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ590010A (en) | 2013-01-25 |
| US20110195080A1 (en) | 2011-08-11 |
| AU2009262243B2 (en) | 2015-01-29 |
| JP5627581B2 (ja) | 2014-11-19 |
| RU2519051C2 (ru) | 2014-06-10 |
| CN102119033A (zh) | 2011-07-06 |
| IL209829A0 (en) | 2011-02-28 |
| ZA201009127B (en) | 2012-02-29 |
| CO6321162A2 (es) | 2011-09-20 |
| BRPI0914300B8 (pt) | 2021-05-25 |
| CA2728735A1 (en) | 2009-12-30 |
| JP2011526285A (ja) | 2011-10-06 |
| CN102119033B (zh) | 2015-04-08 |
| US8425914B2 (en) | 2013-04-23 |
| EP2291194A4 (en) | 2012-11-07 |
| MX2010014078A (es) | 2011-04-11 |
| EP2291194A1 (en) | 2011-03-09 |
| RU2011100105A (ru) | 2012-07-20 |
| KR101627879B1 (ko) | 2016-06-07 |
| EP2291194B1 (en) | 2017-02-22 |
| IL209829A (en) | 2015-09-24 |
| US20130149332A1 (en) | 2013-06-13 |
| BRPI0914300B1 (pt) | 2021-03-23 |
| AU2009262243A1 (en) | 2009-12-30 |
| WO2009158395A1 (en) | 2009-12-30 |
| KR20110042037A (ko) | 2011-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 23/03/2021, OBSERVADAS AS CONDICOES LEGAIS. |
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| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/06/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |