BRPI0911679A2 - composto aciltiouréia, ou sal do mesmo, e seu uso - Google Patents
composto aciltiouréia, ou sal do mesmo, e seu usoInfo
- Publication number
- BRPI0911679A2 BRPI0911679A2 BRPI0911679A BRPI0911679A BRPI0911679A2 BR PI0911679 A2 BRPI0911679 A2 BR PI0911679A2 BR PI0911679 A BRPI0911679 A BR PI0911679A BR PI0911679 A BRPI0911679 A BR PI0911679A BR PI0911679 A2 BRPI0911679 A2 BR PI0911679A2
- Authority
- BR
- Brazil
- Prior art keywords
- salt
- acylthiourea compound
- acylthiourea
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008-102832 | 2008-04-10 | ||
| JP2008102832 | 2008-04-10 | ||
| PCT/JP2009/001655 WO2009125597A1 (ja) | 2008-04-10 | 2009-04-09 | アシルチオウレア化合物又はその塩、及びその用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0911679A2 true BRPI0911679A2 (pt) | 2015-10-13 |
| BRPI0911679B1 BRPI0911679B1 (pt) | 2020-09-29 |
| BRPI0911679B8 BRPI0911679B8 (pt) | 2021-05-25 |
Family
ID=41161733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0911679A BRPI0911679B8 (pt) | 2008-04-10 | 2009-04-09 | composto aciltioureia ou um sal do mesmo, uso do dito composto para tratar câncer, bem como agente farmacêutico, agente antitumoral e composição farmacêutica compreendendo dito composto |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8304427B2 (pt) |
| EP (1) | EP2287155B1 (pt) |
| JP (1) | JP4667537B2 (pt) |
| KR (1) | KR101414931B1 (pt) |
| CN (1) | CN101998951B (pt) |
| AU (1) | AU2009234978B2 (pt) |
| BR (1) | BRPI0911679B8 (pt) |
| CA (1) | CA2720552C (pt) |
| CY (1) | CY1114166T1 (pt) |
| DK (1) | DK2287155T3 (pt) |
| ES (1) | ES2423851T3 (pt) |
| HK (1) | HK1151288A1 (pt) |
| HR (1) | HRP20130984T1 (pt) |
| MX (1) | MX2010011097A (pt) |
| PL (1) | PL2287155T3 (pt) |
| PT (1) | PT2287155E (pt) |
| RU (1) | RU2503664C2 (pt) |
| SI (1) | SI2287155T1 (pt) |
| TW (1) | TWI438193B (pt) |
| WO (1) | WO2009125597A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9314253B2 (en) | 2008-07-01 | 2016-04-19 | Amendia, Inc. | Tissue modification devices and methods |
| AU2009303602B2 (en) | 2008-10-14 | 2012-06-14 | Sunshine Lake Pharma Co., Ltd. | Compounds and methods of use |
| SG173867A1 (en) | 2009-03-21 | 2011-10-28 | Ning Xi | Amino ester derivatives, salts thereof and methods of use |
| WO2012008563A1 (ja) | 2010-07-16 | 2012-01-19 | 協和発酵キリン株式会社 | 含窒素芳香族複素環誘導体 |
| WO2012121273A1 (ja) * | 2011-03-07 | 2012-09-13 | 味の素株式会社 | 塩味増強剤 |
| TWI594986B (zh) | 2011-12-28 | 2017-08-11 | Taiho Pharmaceutical Co Ltd | Antineoplastic agent effect enhancer |
| WO2013111798A1 (ja) | 2012-01-27 | 2013-08-01 | 国立大学法人 富山大学 | セリンラセマーゼ阻害剤 |
| US9149471B2 (en) | 2013-09-30 | 2015-10-06 | National University Corporation Tokyo University Of Agriculture And Technology | Therapeutic agent for osteoporosis |
| EP3293177A4 (en) * | 2015-04-07 | 2018-12-12 | Guangdong Zhongsheng Pharmaceutical Co., Ltd | Tyrosine kinase inhibitor and pharmaceutical composition comprising same |
| ES2863586T3 (es) | 2015-04-30 | 2021-10-11 | Taiho Pharmaceutical Co Ltd | Sal del ácido mesílico de un compuesto de aciltiourea, cristal de la misma y proceso para su producción |
| EP3973962A1 (en) * | 2015-06-25 | 2022-03-30 | Taiho Pharmaceutical Co., Ltd. | Therapeutic agent for fibrosis |
| CN105601566A (zh) * | 2016-02-02 | 2016-05-25 | 张敏 | 一种护理烧伤后感染的药物组合物 |
| WO2018028591A1 (zh) * | 2016-08-09 | 2018-02-15 | 殷建明 | 一种喹啉衍生物及其用途 |
| MY194278A (en) | 2017-02-15 | 2022-11-25 | Taiho Pharmaceutical Co Ltd | Pharmaceutical composition |
| KR102584306B1 (ko) * | 2017-09-08 | 2023-10-04 | 다이호야쿠힌고교 가부시키가이샤 | 항종양제 및 항종양 효과 증강제 |
| KR20210060465A (ko) | 2018-09-18 | 2021-05-26 | 다이호야쿠힌고교 가부시키가이샤 | 아실티오우레아 화합물과 아비라테론의 병용 요법 |
| TW202140426A (zh) | 2020-02-14 | 2021-11-01 | 日商大鵬藥品工業股份有限公司 | 醯基硫脲化合物的製造方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL102548A (en) * | 1991-08-02 | 1998-08-16 | Medivir Ab | Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds |
| US7135466B2 (en) * | 1999-12-24 | 2006-11-14 | Kirin Beer Kabushiki Kaisha | Quinoline and quinazoline derivatives and drugs containing the same |
| DE60137273D1 (de) | 2000-10-20 | 2009-02-12 | Eisai R&D Man Co Ltd | Verfahren zur Herstellung von 4-Phenoxy chinolin Derivaten |
| EP2088141A3 (en) * | 2001-06-22 | 2009-11-18 | Kirin Pharma Kabushiki Kaisha | Quinoline derivatives and quinazoline derivatives capable of inhibiting autophosphorylation of hepatocyte growth factor receptors, and pharmaceutical composition comprising the same |
| US6858637B2 (en) | 2002-03-28 | 2005-02-22 | Neurogen Corporation | Substituted biaryl amides as C5a receptor modulators |
| ES2651730T3 (es) | 2003-09-26 | 2018-01-29 | Exelixis, Inc. | Moduladores c-Met y métodos de uso |
| TW200538120A (en) | 2004-02-20 | 2005-12-01 | Kirin Brewery | Compound having TGF-beta inhibitory activity and pharmaceutical composition containing same |
| US20070270421A1 (en) | 2004-02-27 | 2007-11-22 | Tomohiro Matsushima | Novel pyridine Derivative and Pyrimidine Derivative (1) |
| WO2005121125A1 (en) | 2004-06-09 | 2005-12-22 | Pfizer Inc. | Ether-linked heteroaryl compounds |
| AU2006229343A1 (en) * | 2005-03-28 | 2006-10-05 | Kirin Pharma Kabushiki Kaisha | Thienopyridine derivative, or quinoline derivative, or quinazoline derivative, having c-Met autophosphorylation inhibiting potency |
| CA2603748A1 (en) * | 2005-04-06 | 2006-10-12 | Exelixis, Inc. | C-met modulators and methods of use |
-
2009
- 2009-04-09 MX MX2010011097A patent/MX2010011097A/es active IP Right Grant
- 2009-04-09 CN CN2009801127609A patent/CN101998951B/zh active Active
- 2009-04-09 EP EP09730440.6A patent/EP2287155B1/en active Active
- 2009-04-09 KR KR1020107022154A patent/KR101414931B1/ko active IP Right Grant
- 2009-04-09 US US12/937,312 patent/US8304427B2/en active Active
- 2009-04-09 DK DK09730440.6T patent/DK2287155T3/da active
- 2009-04-09 ES ES09730440T patent/ES2423851T3/es active Active
- 2009-04-09 AU AU2009234978A patent/AU2009234978B2/en active Active
- 2009-04-09 PL PL09730440T patent/PL2287155T3/pl unknown
- 2009-04-09 CA CA2720552A patent/CA2720552C/en active Active
- 2009-04-09 WO PCT/JP2009/001655 patent/WO2009125597A1/ja active Application Filing
- 2009-04-09 JP JP2010507175A patent/JP4667537B2/ja active Active
- 2009-04-09 SI SI200930710T patent/SI2287155T1/sl unknown
- 2009-04-09 BR BRPI0911679A patent/BRPI0911679B8/pt active IP Right Grant
- 2009-04-09 TW TW098111876A patent/TWI438193B/zh active
- 2009-04-09 RU RU2010145526/04A patent/RU2503664C2/ru active
- 2009-04-09 PT PT97304406T patent/PT2287155E/pt unknown
-
2011
- 2011-05-30 HK HK11105356.4A patent/HK1151288A1/xx unknown
-
2013
- 2013-07-23 CY CY20131100625T patent/CY1114166T1/el unknown
- 2013-10-17 HR HRP20130984AT patent/HRP20130984T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4667537B2 (ja) | 2011-04-13 |
| AU2009234978A1 (en) | 2009-10-15 |
| CN101998951B (zh) | 2013-07-17 |
| HRP20130984T1 (hr) | 2013-11-22 |
| PL2287155T3 (pl) | 2013-12-31 |
| TWI438193B (zh) | 2014-05-21 |
| WO2009125597A1 (ja) | 2009-10-15 |
| RU2010145526A (ru) | 2012-05-20 |
| EP2287155A4 (en) | 2012-05-09 |
| KR101414931B1 (ko) | 2014-07-04 |
| CA2720552A1 (en) | 2009-10-15 |
| JPWO2009125597A1 (ja) | 2011-08-04 |
| TW201000451A (en) | 2010-01-01 |
| ES2423851T3 (es) | 2013-09-24 |
| KR20100132023A (ko) | 2010-12-16 |
| BRPI0911679B1 (pt) | 2020-09-29 |
| MX2010011097A (es) | 2010-11-01 |
| SI2287155T1 (sl) | 2013-10-30 |
| DK2287155T3 (da) | 2013-07-29 |
| PT2287155E (pt) | 2013-07-26 |
| AU2009234978B2 (en) | 2014-03-06 |
| BRPI0911679B8 (pt) | 2021-05-25 |
| EP2287155A1 (en) | 2011-02-23 |
| CY1114166T1 (el) | 2016-08-31 |
| HK1151288A1 (en) | 2012-01-27 |
| CN101998951A (zh) | 2011-03-30 |
| EP2287155B1 (en) | 2013-07-17 |
| RU2503664C2 (ru) | 2014-01-10 |
| US8304427B2 (en) | 2012-11-06 |
| CA2720552C (en) | 2016-06-14 |
| US20110034439A1 (en) | 2011-02-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 29/09/2020, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/04/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |