BRPI0911679A2 - composto aciltiouréia, ou sal do mesmo, e seu uso - Google Patents
composto aciltiouréia, ou sal do mesmo, e seu usoInfo
- Publication number
- BRPI0911679A2 BRPI0911679A2 BRPI0911679A BRPI0911679A BRPI0911679A2 BR PI0911679 A2 BRPI0911679 A2 BR PI0911679A2 BR PI0911679 A BRPI0911679 A BR PI0911679A BR PI0911679 A BRPI0911679 A BR PI0911679A BR PI0911679 A2 BRPI0911679 A2 BR PI0911679A2
- Authority
- BR
- Brazil
- Prior art keywords
- salt
- acylthiourea compound
- acylthiourea
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008-102832 | 2008-04-10 | ||
JP2008102832 | 2008-04-10 | ||
PCT/JP2009/001655 WO2009125597A1 (ja) | 2008-04-10 | 2009-04-09 | アシルチオウレア化合物又はその塩、及びその用途 |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0911679A2 true BRPI0911679A2 (pt) | 2015-10-13 |
BRPI0911679B1 BRPI0911679B1 (pt) | 2020-09-29 |
BRPI0911679B8 BRPI0911679B8 (pt) | 2021-05-25 |
Family
ID=41161733
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0911679A BRPI0911679B8 (pt) | 2008-04-10 | 2009-04-09 | composto aciltioureia ou um sal do mesmo, uso do dito composto para tratar câncer, bem como agente farmacêutico, agente antitumoral e composição farmacêutica compreendendo dito composto |
Country Status (20)
Country | Link |
---|---|
US (1) | US8304427B2 (pt) |
EP (1) | EP2287155B1 (pt) |
JP (1) | JP4667537B2 (pt) |
KR (1) | KR101414931B1 (pt) |
CN (1) | CN101998951B (pt) |
AU (1) | AU2009234978B2 (pt) |
BR (1) | BRPI0911679B8 (pt) |
CA (1) | CA2720552C (pt) |
CY (1) | CY1114166T1 (pt) |
DK (1) | DK2287155T3 (pt) |
ES (1) | ES2423851T3 (pt) |
HK (1) | HK1151288A1 (pt) |
HR (1) | HRP20130984T1 (pt) |
MX (1) | MX2010011097A (pt) |
PL (1) | PL2287155T3 (pt) |
PT (1) | PT2287155E (pt) |
RU (1) | RU2503664C2 (pt) |
SI (1) | SI2287155T1 (pt) |
TW (1) | TWI438193B (pt) |
WO (1) | WO2009125597A1 (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9314253B2 (en) | 2008-07-01 | 2016-04-19 | Amendia, Inc. | Tissue modification devices and methods |
EP2532657B9 (en) | 2008-10-14 | 2017-04-19 | Sunshine Lake Pharma Co., Ltd. | Compounds and methods of use |
AU2010229147B2 (en) | 2009-03-21 | 2012-07-05 | Sunshine Lake Pharma Co., Ltd. | Amino ester derivatives, salts thereof and methods of use |
WO2012008563A1 (ja) | 2010-07-16 | 2012-01-19 | 協和発酵キリン株式会社 | 含窒素芳香族複素環誘導体 |
EP2684468A4 (en) * | 2011-03-07 | 2014-08-27 | Ajinomoto Kk | EXTENDER OF SALTY TASTE |
TWI594986B (zh) * | 2011-12-28 | 2017-08-11 | Taiho Pharmaceutical Co Ltd | Antineoplastic agent effect enhancer |
CA2863006A1 (en) | 2012-01-27 | 2013-08-01 | National University Corporation University Of Toyama | Serine racemase inhibitor |
US9149471B2 (en) | 2013-09-30 | 2015-10-06 | National University Corporation Tokyo University Of Agriculture And Technology | Therapeutic agent for osteoporosis |
EP3293177A4 (en) * | 2015-04-07 | 2018-12-12 | Guangdong Zhongsheng Pharmaceutical Co., Ltd | Tyrosine kinase inhibitor and pharmaceutical composition comprising same |
PT3290405T (pt) * | 2015-04-30 | 2021-03-23 | Taiho Pharmaceutical Co Ltd | Sal de ácido mesílico de composto de aciltioureia, cristal do mesmo, e respetivos processos de produção |
WO2016208744A1 (ja) | 2015-06-25 | 2016-12-29 | 大鵬薬品工業株式会社 | 線維症治療剤 |
CN105601566A (zh) * | 2016-02-02 | 2016-05-25 | 张敏 | 一种护理烧伤后感染的药物组合物 |
WO2018028591A1 (zh) * | 2016-08-09 | 2018-02-15 | 殷建明 | 一种喹啉衍生物及其用途 |
MX2021007061A (es) | 2017-02-15 | 2022-10-07 | Taiho Pharmaceutical Co Ltd | Composición farmacéutica que comprende 4-(2-fluoro-4-(3-(2- fenilacetil)tioureido)fenoxi)-7-metoxi-n-metilquinolina-6-carboxa mida e hidroxipropil-b-ciclodextrina. |
AU2018329881B2 (en) * | 2017-09-08 | 2021-12-02 | Taiho Pharmaceutical Co., Ltd. | Antitumor agent and antitumor effect potentiator |
EP3854395A4 (en) | 2018-09-18 | 2022-06-15 | Taiho Pharmaceutical Co., Ltd. | COMBINATION THERAPY OF AN ACYLTHIOREA COMPOUND AND ABIRATERON |
TW202140426A (zh) * | 2020-02-14 | 2021-11-01 | 日商大鵬藥品工業股份有限公司 | 醯基硫脲化合物的製造方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL102548A (en) * | 1991-08-02 | 1998-08-16 | Medivir Ab | Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds |
US7135466B2 (en) * | 1999-12-24 | 2006-11-14 | Kirin Beer Kabushiki Kaisha | Quinoline and quinazoline derivatives and drugs containing the same |
ES2318649T3 (es) * | 2000-10-20 | 2009-05-01 | EISAI R&D MANAGEMENT CO., LTD. | Procedimiento de preparacion de derivados de 4-fenoxi quinolinas. |
KR100883731B1 (ko) | 2001-06-22 | 2009-02-12 | 기린 파마 가부시끼가이샤 | 간세포 증식 인자 수용체 자기 인산화를 저해하는 퀴놀린유도체 및 퀴나졸린 유도체 및 이들을 함유하는 의약 조성물 |
US6858637B2 (en) | 2002-03-28 | 2005-02-22 | Neurogen Corporation | Substituted biaryl amides as C5a receptor modulators |
JP4638436B2 (ja) | 2003-09-26 | 2011-02-23 | エグゼリクシス, インコーポレイテッド | c−Metモジュレーターおよびその使用 |
TW200538120A (en) | 2004-02-20 | 2005-12-01 | Kirin Brewery | Compound having TGF-beta inhibitory activity and pharmaceutical composition containing same |
US20070270421A1 (en) | 2004-02-27 | 2007-11-22 | Tomohiro Matsushima | Novel pyridine Derivative and Pyrimidine Derivative (1) |
WO2005121125A1 (en) * | 2004-06-09 | 2005-12-22 | Pfizer Inc. | Ether-linked heteroaryl compounds |
AU2006229343A1 (en) * | 2005-03-28 | 2006-10-05 | Kirin Pharma Kabushiki Kaisha | Thienopyridine derivative, or quinoline derivative, or quinazoline derivative, having c-Met autophosphorylation inhibiting potency |
JP2008537748A (ja) * | 2005-04-06 | 2008-09-25 | エクセリクシス、インコーポレイテッド | c−Metモジュレーター及び使用方法 |
-
2009
- 2009-04-09 TW TW098111876A patent/TWI438193B/zh active
- 2009-04-09 US US12/937,312 patent/US8304427B2/en active Active
- 2009-04-09 PT PT97304406T patent/PT2287155E/pt unknown
- 2009-04-09 JP JP2010507175A patent/JP4667537B2/ja active Active
- 2009-04-09 PL PL09730440T patent/PL2287155T3/pl unknown
- 2009-04-09 DK DK09730440.6T patent/DK2287155T3/da active
- 2009-04-09 EP EP09730440.6A patent/EP2287155B1/en active Active
- 2009-04-09 CA CA2720552A patent/CA2720552C/en active Active
- 2009-04-09 AU AU2009234978A patent/AU2009234978B2/en active Active
- 2009-04-09 CN CN2009801127609A patent/CN101998951B/zh active Active
- 2009-04-09 WO PCT/JP2009/001655 patent/WO2009125597A1/ja active Application Filing
- 2009-04-09 SI SI200930710T patent/SI2287155T1/sl unknown
- 2009-04-09 MX MX2010011097A patent/MX2010011097A/es active IP Right Grant
- 2009-04-09 KR KR1020107022154A patent/KR101414931B1/ko active IP Right Grant
- 2009-04-09 ES ES09730440T patent/ES2423851T3/es active Active
- 2009-04-09 RU RU2010145526/04A patent/RU2503664C2/ru active
- 2009-04-09 BR BRPI0911679A patent/BRPI0911679B8/pt active IP Right Grant
-
2011
- 2011-05-30 HK HK11105356.4A patent/HK1151288A1/xx unknown
-
2013
- 2013-07-23 CY CY20131100625T patent/CY1114166T1/el unknown
- 2013-10-17 HR HRP20130984AT patent/HRP20130984T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
MX2010011097A (es) | 2010-11-01 |
HK1151288A1 (en) | 2012-01-27 |
CY1114166T1 (el) | 2016-08-31 |
AU2009234978B2 (en) | 2014-03-06 |
TWI438193B (zh) | 2014-05-21 |
SI2287155T1 (sl) | 2013-10-30 |
US8304427B2 (en) | 2012-11-06 |
CN101998951A (zh) | 2011-03-30 |
JPWO2009125597A1 (ja) | 2011-08-04 |
JP4667537B2 (ja) | 2011-04-13 |
EP2287155A1 (en) | 2011-02-23 |
DK2287155T3 (da) | 2013-07-29 |
BRPI0911679B1 (pt) | 2020-09-29 |
WO2009125597A1 (ja) | 2009-10-15 |
RU2503664C2 (ru) | 2014-01-10 |
US20110034439A1 (en) | 2011-02-10 |
EP2287155B1 (en) | 2013-07-17 |
TW201000451A (en) | 2010-01-01 |
AU2009234978A1 (en) | 2009-10-15 |
RU2010145526A (ru) | 2012-05-20 |
CN101998951B (zh) | 2013-07-17 |
BRPI0911679B8 (pt) | 2021-05-25 |
ES2423851T3 (es) | 2013-09-24 |
KR101414931B1 (ko) | 2014-07-04 |
HRP20130984T1 (hr) | 2013-11-22 |
CA2720552C (en) | 2016-06-14 |
EP2287155A4 (en) | 2012-05-09 |
PL2287155T3 (pl) | 2013-12-31 |
PT2287155E (pt) | 2013-07-26 |
CA2720552A1 (en) | 2009-10-15 |
KR20100132023A (ko) | 2010-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 29/09/2020, OBSERVADAS AS CONDICOES LEGAIS. |
|
B16C | Correction of notification of the grant |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/04/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |