BRPI0910038A2 - método para detecção de igf1r/chr 15 em células tumorais circulantes com o uso de fish (hibridização in situ fluorescente) - Google Patents
método para detecção de igf1r/chr 15 em células tumorais circulantes com o uso de fish (hibridização in situ fluorescente)Info
- Publication number
- BRPI0910038A2 BRPI0910038A2 BRPI0910038A BRPI0910038A BRPI0910038A2 BR PI0910038 A2 BRPI0910038 A2 BR PI0910038A2 BR PI0910038 A BRPI0910038 A BR PI0910038A BR PI0910038 A BRPI0910038 A BR PI0910038A BR PI0910038 A2 BRPI0910038 A2 BR PI0910038A2
- Authority
- BR
- Brazil
- Prior art keywords
- igf1r
- chr
- fish
- fluorescent
- detection
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3916208P | 2008-03-25 | 2008-03-25 | |
| PCT/US2009/038226 WO2009120767A1 (en) | 2008-03-25 | 2009-03-25 | A method for detecting igf1r/chr 15 circulating tumor cells using fish |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0910038A2 true BRPI0910038A2 (pt) | 2015-12-29 |
Family
ID=41114319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0910038A BRPI0910038A2 (pt) | 2008-03-25 | 2009-03-25 | método para detecção de igf1r/chr 15 em células tumorais circulantes com o uso de fish (hibridização in situ fluorescente) |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090258365A1 (pt) |
| EP (1) | EP2279266B1 (pt) |
| JP (1) | JP2011515109A (pt) |
| KR (1) | KR20100131494A (pt) |
| CN (1) | CN101978076B (pt) |
| BR (1) | BRPI0910038A2 (pt) |
| CA (1) | CA2717975A1 (pt) |
| DK (1) | DK2279266T3 (pt) |
| ES (1) | ES2652467T3 (pt) |
| IL (1) | IL207895A (pt) |
| MX (1) | MX2010010465A (pt) |
| WO (1) | WO2009120767A1 (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20090368A1 (es) | 2007-06-19 | 2009-04-28 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
| WO2010068812A1 (en) | 2008-12-10 | 2010-06-17 | Abqmr, Inc. | Nuclear magnetic resonance apparatus, methods and associated technology |
| HUE026374T2 (en) | 2008-12-12 | 2016-05-30 | Boehringer Ingelheim Int | Anti-IGF antibody |
| CN102782498A (zh) | 2009-10-21 | 2012-11-14 | 斯克里普斯研究所 | 用非稀有细胞检测稀有细胞的方法 |
| EP2544672A1 (en) | 2010-03-09 | 2013-01-16 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
| US20110262989A1 (en) | 2010-04-21 | 2011-10-27 | Nanomr, Inc. | Isolating a target analyte from a body fluid |
| US8841104B2 (en) | 2010-04-21 | 2014-09-23 | Nanomr, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
| US9428547B2 (en) | 2010-04-21 | 2016-08-30 | Dna Electronics, Inc. | Compositions for isolating a target analyte from a heterogeneous sample |
| US9476812B2 (en) | 2010-04-21 | 2016-10-25 | Dna Electronics, Inc. | Methods for isolating a target analyte from a heterogeneous sample |
| WO2012106556A2 (en) | 2011-02-02 | 2012-08-09 | Amgen Inc. | Methods and compositons relating to inhibition of igf-1r |
| JP6198717B2 (ja) | 2012-03-28 | 2017-09-20 | 株式会社オンチップ・バイオテクノロジーズ | 末梢循環腫瘍細胞単位の悪性度の検出方法及びそのキット |
| WO2013148458A1 (en) * | 2012-03-30 | 2013-10-03 | Clarient Diagnostic Services, Inc. | Methods for generating an image of a biological sample |
| US10000557B2 (en) | 2012-12-19 | 2018-06-19 | Dnae Group Holdings Limited | Methods for raising antibodies |
| US9804069B2 (en) | 2012-12-19 | 2017-10-31 | Dnae Group Holdings Limited | Methods for degrading nucleic acid |
| US9599610B2 (en) | 2012-12-19 | 2017-03-21 | Dnae Group Holdings Limited | Target capture system |
| US9551704B2 (en) | 2012-12-19 | 2017-01-24 | Dna Electronics, Inc. | Target detection |
| US9434940B2 (en) | 2012-12-19 | 2016-09-06 | Dna Electronics, Inc. | Methods for universal target capture |
| US9995742B2 (en) | 2012-12-19 | 2018-06-12 | Dnae Group Holdings Limited | Sample entry |
| US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
| KR20140147041A (ko) | 2013-06-18 | 2014-12-29 | 주식회사 엘지화학 | 셀 포장재료 및 그 제조방법 |
| WO2015024020A1 (en) | 2013-08-16 | 2015-02-19 | The General Hospital Corporation | Portable diffraction-based imaging and diagnostic systems and methods |
| EA201691496A1 (ru) | 2014-01-27 | 2016-12-30 | Эпик Сайенсиз, Инк. | Диагностика биомаркеров рака предстательной железы с помощью циркулирующих опухолевых клеток |
| EA201691682A1 (ru) * | 2014-02-21 | 2017-02-28 | Эпик Сайенсиз, Инк. | Способы анализирования редких циркулирующих в крови клеток |
| JP6746845B2 (ja) * | 2015-04-22 | 2020-08-26 | イミューノメディクス、インコーポレイテッドＩｍｍｕｎｏｍｅｄｉｃｓ， Ｉｎｃ． | 循環ｔｒｏｐ−２陽性癌細胞の単離、検出、診断及び／または特徴付け |
| US11149299B2 (en) * | 2015-06-25 | 2021-10-19 | Ramesh Vallabhaneni | Method and system for multiplex profiling of chromosomes in biological samples using target-specific DNA probes |
| US20210192721A1 (en) * | 2017-10-26 | 2021-06-24 | Konica Minolta, Inc. | Image Processing Device, In-Focus Position Specifying Method, and In-Focus Position Specifying Program |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5447841A (en) * | 1986-01-16 | 1995-09-05 | The Regents Of The Univ. Of California | Methods for chromosome-specific staining |
| US6475720B1 (en) * | 1986-01-16 | 2002-11-05 | The Regents Of The University Of California | Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17 |
| US6277569B1 (en) * | 1990-09-20 | 2001-08-21 | Vysis, Inc. | Methods for multiple direct label probe detection of multiple chromosomes or regions thereof by in situ hybridization |
| US6790366B2 (en) * | 1996-06-07 | 2004-09-14 | Immunivest Corporation | Magnetic separation apparatus and methods |
| US6660159B1 (en) * | 1996-06-07 | 2003-12-09 | Immunivest Corporation | Magnetic separation apparatus and methods |
| US6890426B2 (en) * | 1996-06-07 | 2005-05-10 | Immunivest Corporation | Magnetic separation apparatus and methods |
| GB9716664D0 (en) * | 1997-08-06 | 1997-10-15 | Norwegian Inst Of Fisheries & | A method of removing nucleic acid contamination reactions |
| US6063586A (en) * | 1997-09-03 | 2000-05-16 | Eye & Ear Foundation | Diagnostic protocol |
| KR100399475B1 (ko) * | 1998-02-12 | 2003-09-29 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 순환 중인 암세포의 신속하고 효과적인 분리 방법 및 이를위한 제제 |
| US20020172987A1 (en) * | 1998-02-12 | 2002-11-21 | Terstappen Leon W.M.M. | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| US6174681B1 (en) * | 1999-03-05 | 2001-01-16 | Mayo Foundation For Medical Education And Research | Method and probe set for detecting cancer |
| AU4056500A (en) | 1999-04-01 | 2000-10-23 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Methods for detecting cancer cells |
| AU5606500A (en) * | 1999-06-18 | 2001-01-09 | Applied Imaging Corporation | High efficiency methods for combined immunocytochemistry and in-situ hybridization |
| US20030022166A1 (en) * | 2001-01-19 | 2003-01-30 | Colin Collins | Repeat-free probes for molecular cytogenetics |
| EP1362124B1 (en) * | 2001-02-20 | 2011-07-06 | Vysis, Inc. | Methods and probes for the detection of cancer |
| AU2002346662A1 (en) * | 2001-12-04 | 2003-06-17 | Euregen Llc | Methods and compositions for selectively cleaving dna containing duplex acids in a complex nucleic acid mixture |
| US7468356B2 (en) * | 2003-02-11 | 2008-12-23 | Antisense Therapeutics Ltd. | Modulation of insulin like growth factor I receptor expression |
| JP4593557B2 (ja) | 2003-02-27 | 2010-12-08 | ベリデックス・リミテッド・ライアビリティ・カンパニー | 循環腫瘍細胞（ｃｔｃ）：転移癌患者における増悪までの時間、生存および療法に対する応答の早期評価 |
| US20050059021A1 (en) * | 2003-09-15 | 2005-03-17 | Performance Genomics, Inc. | Insulin-like growth factor-1 receptor (IGF-1R) polymorphic alleles and use of the same to identify DNA markers for reproductive longevity |
| US20070037173A1 (en) * | 2005-08-12 | 2007-02-15 | Allard Jeffrey W | Circulating tumor cells (CTC's): early assessment of time to progression, survival and response to therapy in metastatic cancer patients |
| WO2007053245A2 (en) * | 2005-09-20 | 2007-05-10 | Immunivest Corporation | Methods and composition to generate unique sequence dna probes, iabeling of dna probes and the use of these probes |
| WO2007053142A1 (en) * | 2005-11-03 | 2007-05-10 | Immunivest Corporation | Agr2 and tff3 regulation in the diagnosis and treatment of cancer |
| US20110027777A1 (en) * | 2006-04-01 | 2011-02-03 | Dako Denmark | Method for performing prognosis for high-risk breast cancer patients using top2a gene aberrations |
| BRPI0712225A8 (pt) | 2006-06-02 | 2019-01-22 | Pfizer Producs Inc | métodos para prever e monitorar a eficácia da terapia antagonista de igf-1r |
-
2009
- 2009-03-23 US US12/409,190 patent/US20090258365A1/en not_active Abandoned
- 2009-03-25 BR BRPI0910038A patent/BRPI0910038A2/pt not_active IP Right Cessation
- 2009-03-25 WO PCT/US2009/038226 patent/WO2009120767A1/en active Application Filing
- 2009-03-25 DK DK09725711.7T patent/DK2279266T3/en active
- 2009-03-25 ES ES09725711.7T patent/ES2652467T3/es active Active
- 2009-03-25 KR KR1020107023513A patent/KR20100131494A/ko not_active Application Discontinuation
- 2009-03-25 CA CA2717975A patent/CA2717975A1/en not_active Abandoned
- 2009-03-25 EP EP09725711.7A patent/EP2279266B1/en not_active Not-in-force
- 2009-03-25 MX MX2010010465A patent/MX2010010465A/es not_active Application Discontinuation
- 2009-03-25 CN CN200980111141.8A patent/CN101978076B/zh not_active Expired - Fee Related
- 2009-03-25 JP JP2011502015A patent/JP2011515109A/ja active Pending
-
2010
- 2010-08-31 IL IL207895A patent/IL207895A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101978076B (zh) | 2016-06-01 |
| CA2717975A1 (en) | 2009-10-01 |
| IL207895A0 (en) | 2010-12-30 |
| CN101978076A (zh) | 2011-02-16 |
| US20090258365A1 (en) | 2009-10-15 |
| EP2279266A1 (en) | 2011-02-02 |
| EP2279266A4 (en) | 2011-08-10 |
| IL207895A (en) | 2015-09-24 |
| MX2010010465A (es) | 2010-10-20 |
| JP2011515109A (ja) | 2011-05-19 |
| EP2279266B1 (en) | 2017-10-11 |
| WO2009120767A1 (en) | 2009-10-01 |
| ES2652467T3 (es) | 2018-02-02 |
| KR20100131494A (ko) | 2010-12-15 |
| DK2279266T3 (en) | 2017-12-18 |
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Legal Events
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| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2508 DE 29-01-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |