BRPI0909791A8 - Cartucho, dispositivo sensor e método para detecção de componentes alvo em uma amostra líquida, e, uso do cartucho ou do dispositivo sensor. - Google Patents
Cartucho, dispositivo sensor e método para detecção de componentes alvo em uma amostra líquida, e, uso do cartucho ou do dispositivo sensor.Info
- Publication number
- BRPI0909791A8 BRPI0909791A8 BRPI0909791A BRPI0909791A BRPI0909791A8 BR PI0909791 A8 BRPI0909791 A8 BR PI0909791A8 BR PI0909791 A BRPI0909791 A BR PI0909791A BR PI0909791 A BRPI0909791 A BR PI0909791A BR PI0909791 A8 BRPI0909791 A8 BR PI0909791A8
- Authority
- BR
- Brazil
- Prior art keywords
- cartridge
- sensing device
- target components
- liquid sample
- detecting target
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/282—Magnetic plugs and dipsticks with associated accumulation indicator, e.g. Hall sensor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
- G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9486—Analgesics, e.g. opiates, aspirine
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Electrochemistry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
CARTUCHO, DISPOSITIVO SENSOR E MÉTODO PARA DETECÇÃO DE COMPONENTES ALVO EM UMA AMOSTRA LÍQUIDA, E, USO DO CARTUCHO OU DO DISPOSITIVO SENSOR. A invenção diz respeito a um cartucho (100) e um correspondente dispositivo sensor para a detecção de componentes-alvo em uma amostra líquida. O cartucho (100) compreende uma câmara de amostra (SC), pelo menos, dois reservatórios (131, 132) que podem ser fornecidos com partículas magnéticas (MP, MP'), e, pelo menos duas correspondentes zonas sensitivas (121, 122) nas quais as partículas magnéticas dissolvidas e/ou os componentes-alvo podem ser detectados. Quando um campo de acionamento magnético (B) de uma dada configuração é estabelecido na câmara de amostra, as partículas magnéticas de diferentes reservatórios migram predominantemente para diferentes zonas sensitivas. Desta forma, a mistura de partículas magnéticas pode ser evitada.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08102671 | 2008-03-17 | ||
PCT/IB2009/051021 WO2009115951A1 (en) | 2008-03-17 | 2009-03-11 | Cartridge for assays with magnetic particles |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0909791A2 BRPI0909791A2 (pt) | 2015-08-11 |
BRPI0909791A8 true BRPI0909791A8 (pt) | 2016-08-02 |
Family
ID=40641647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0909791A BRPI0909791A8 (pt) | 2008-03-17 | 2009-03-11 | Cartucho, dispositivo sensor e método para detecção de componentes alvo em uma amostra líquida, e, uso do cartucho ou do dispositivo sensor. |
Country Status (8)
Country | Link |
---|---|
US (2) | US20110014719A1 (pt) |
EP (1) | EP2263084B1 (pt) |
JP (1) | JP5628784B2 (pt) |
CN (1) | CN101978267B (pt) |
BR (1) | BRPI0909791A8 (pt) |
RU (1) | RU2505816C2 (pt) |
WO (1) | WO2009115951A1 (pt) |
ZA (1) | ZA201007366B (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102165318A (zh) * | 2008-09-26 | 2011-08-24 | 皇家飞利浦电子股份有限公司 | 磁性标签传感器和筒体 |
CN102197308A (zh) * | 2008-10-31 | 2011-09-21 | 皇家飞利浦电子股份有限公司 | 具有多腔室筒体的生物传感器 |
US9086396B2 (en) | 2008-11-28 | 2015-07-21 | Roche Molecular Systems, Inc. | System and method for the automated processing of fluids, method for determining the matching of objects |
CN102597774B (zh) | 2009-09-23 | 2015-05-13 | 皇家飞利浦电子股份有限公司 | 利用多种磁性标记示踪结合试剂的结合测定 |
EP2513637B1 (en) * | 2009-12-18 | 2020-07-15 | Koninklijke Philips N.V. | Substance determining apparatus |
CN102947900A (zh) * | 2010-06-22 | 2013-02-27 | 皇家飞利浦电子股份有限公司 | 磁性颗粒及其聚类的检测 |
WO2012004723A1 (en) | 2010-07-05 | 2012-01-12 | Koninklijke Philips Electronics N.V. | Examination system with sample incubation |
BR112013013109B1 (pt) | 2010-11-30 | 2021-02-09 | Koninklijke Philips N.V. | dispositivo sensor para a detecção de partículas magnéticas em uma câmara de amostras com uma superfície de contato em que as partículas magnéticas podem ser coletadas |
EP2541230A1 (en) * | 2011-06-30 | 2013-01-02 | Koninklijke Philips Electronics N.V. | Detection of clusters of magnetic particles |
DK2800970T3 (en) | 2012-01-04 | 2017-01-16 | Magnomics S A | Monolithic device for combining CMOS with magnetoresistive sensors |
WO2013108168A2 (en) * | 2012-01-16 | 2013-07-25 | Koninklijke Philips N.V. | Determining a presence of target molecules in a body fluid comprising cells |
CN102600966A (zh) * | 2012-03-06 | 2012-07-25 | 南昌大学 | 简易磁珠分离装置 |
CN102600967A (zh) * | 2012-03-06 | 2012-07-25 | 南昌大学 | 一种智能控制磁分离器 |
WO2014062719A2 (en) | 2012-10-15 | 2014-04-24 | Nanocellect Biomedical, Inc. | Systems, apparatus, and methods for sorting particles |
CN102935996B (zh) * | 2012-10-18 | 2015-04-22 | 上海交通大学 | 血清肿瘤标志物检测的微型化磁通门生物传感器制作方法 |
JP2014232032A (ja) * | 2013-05-29 | 2014-12-11 | 独立行政法人国立長寿医療研究センター | 化学・物理現象検出方法及びその装置 |
RU2569766C2 (ru) * | 2014-01-24 | 2015-11-27 | Общество с ограниченной ответственностью "Химмотолог" | Устройство для автоматического определения качества смазочных материалов |
CN104407113B (zh) * | 2014-11-04 | 2016-09-07 | 上海交通大学 | 食品中致病菌检测的微型化磁通门生物传感器 |
EP3274714B1 (en) * | 2015-03-26 | 2019-07-03 | Koninklijke Philips N.V. | Manufacturing of a biosensor cartridge |
US10261076B2 (en) * | 2015-10-02 | 2019-04-16 | The Board Of Trustees Of The Leland Stanford Junior University | Method for detecting small molecule analytes using magnetoresistant sensors |
US9702748B2 (en) | 2015-10-14 | 2017-07-11 | International Business Machines Corporation | Graphene-based magnetic hall sensor for fluid flow analysis at nanoscale level |
WO2017156127A1 (en) * | 2016-03-11 | 2017-09-14 | Qorvo Us, Inc. | Baw sensor fluidic device with increased dynamic measurement range |
JPWO2020170735A1 (ja) * | 2019-02-22 | 2021-12-16 | Tdk株式会社 | 血液浄化装置及び血液の浄化方法 |
US11977086B2 (en) | 2019-03-21 | 2024-05-07 | Hound Labs, Inc. | Biomarker detection from breath samples |
Family Cites Families (23)
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US5846708A (en) | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
US5981297A (en) * | 1997-02-05 | 1999-11-09 | The United States Of America As Represented By The Secretary Of The Navy | Biosensor using magnetically-detected label |
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EP1365241A2 (en) * | 2000-08-21 | 2003-11-26 | Darashkevitch, Oleg | Method and device for simultaneous detection of multiple components in a mixture |
US7232691B2 (en) * | 2001-11-27 | 2007-06-19 | Los Alamos National Security, Llc | Bioassay and biomolecular identification, sorting, and collection methods using magnetic microspheres |
TWI306153B (en) * | 2002-01-29 | 2009-02-11 | Asahi Chemical Ind | Biosensor, magnetic molecule measurement method, and measurement object measuring method |
US20060134713A1 (en) * | 2002-03-21 | 2006-06-22 | Lifescan, Inc. | Biosensor apparatus and methods of use |
US20040197845A1 (en) * | 2002-08-30 | 2004-10-07 | Arjang Hassibi | Methods and apparatus for pathogen detection, identification and/or quantification |
WO2005010543A1 (en) | 2003-07-30 | 2005-02-03 | Koninklijke Philips Electronics N.V. | On-chip magnetic sensor device with suppressed cross-talk |
EP1685418A2 (en) | 2003-07-30 | 2006-08-02 | Koninklijke Philips Electronics N.V. | On-chip magnetic particle sensor with improved snr |
JP2005315677A (ja) * | 2004-04-28 | 2005-11-10 | Canon Inc | 検出装置および検出方法 |
JP4680587B2 (ja) * | 2004-12-28 | 2011-05-11 | 旭化成株式会社 | バイオセンサ、対象物測定方法、バイオセンサ用カートリッジ及び不織布 |
RU2415433C2 (ru) | 2005-01-31 | 2011-03-27 | Конинклейке Филипс Электроникс Н.В. | Быстрое и чувствительное измерение биоинформации |
NZ590930A (en) * | 2005-05-09 | 2012-11-30 | Theranos Inc | Improving the calibration accuracy of a fluidic system by comparing test readings with a calibration curve and then adjusting the signal output |
CN101198870A (zh) * | 2005-06-17 | 2008-06-11 | 皇家飞利浦电子股份有限公司 | 精密磁性生物传感器 |
WO2007002579A2 (en) * | 2005-06-23 | 2007-01-04 | Bioveris Corporation | Assay cartridges and methods for point of care instruments |
JP5188091B2 (ja) * | 2006-03-31 | 2013-04-24 | キヤノン株式会社 | センサ素子、ならびにこの素子を用いた磁性粒子の検出方法及び標的物質の検出方法 |
EP2018537B1 (en) * | 2006-05-10 | 2013-07-17 | Koninklijke Philips Electronics N.V. | Rapid magnetic biosensor |
CN101021530B (zh) * | 2007-03-26 | 2011-08-31 | 南京大学 | 自动化通道分辨化学发光多组分免疫检测系统及分析方法 |
EP2017618A1 (en) * | 2007-07-20 | 2009-01-21 | Koninklijke Philips Electronics N.V. | Methods and systems for detecting |
EP2034324A3 (en) * | 2007-07-20 | 2010-06-16 | Koninklijke Philips Electronics N.V. | Sensor cartridge |
-
2009
- 2009-03-11 RU RU2010142278/15A patent/RU2505816C2/ru not_active IP Right Cessation
- 2009-03-11 JP JP2011500322A patent/JP5628784B2/ja active Active
- 2009-03-11 BR BRPI0909791A patent/BRPI0909791A8/pt not_active IP Right Cessation
- 2009-03-11 US US12/922,887 patent/US20110014719A1/en not_active Abandoned
- 2009-03-11 CN CN200980109532.6A patent/CN101978267B/zh active Active
- 2009-03-11 EP EP09723313.4A patent/EP2263084B1/en active Active
- 2009-03-11 WO PCT/IB2009/051021 patent/WO2009115951A1/en active Application Filing
-
2010
- 2010-10-14 ZA ZA2010/07366A patent/ZA201007366B/en unknown
-
2016
- 2016-06-16 US US15/184,280 patent/US10006907B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20110014719A1 (en) | 2011-01-20 |
JP2011516832A (ja) | 2011-05-26 |
WO2009115951A1 (en) | 2009-09-24 |
US20160291004A1 (en) | 2016-10-06 |
RU2505816C2 (ru) | 2014-01-27 |
EP2263084A1 (en) | 2010-12-22 |
CN101978267B (zh) | 2017-04-26 |
CN101978267A (zh) | 2011-02-16 |
RU2010142278A (ru) | 2012-04-27 |
ZA201007366B (en) | 2012-03-28 |
BRPI0909791A2 (pt) | 2015-08-11 |
US10006907B2 (en) | 2018-06-26 |
EP2263084B1 (en) | 2017-02-22 |
JP5628784B2 (ja) | 2014-11-19 |
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