BRPI0907485A2 - Polipeptídeos de ligação a antígeno contra degeneração de cartilagem - Google Patents

Polipeptídeos de ligação a antígeno contra degeneração de cartilagem

Info

Publication number
BRPI0907485A2
BRPI0907485A2 BRPI0907485-6A BRPI0907485A BRPI0907485A2 BR PI0907485 A2 BRPI0907485 A2 BR PI0907485A2 BR PI0907485 A BRPI0907485 A BR PI0907485A BR PI0907485 A2 BRPI0907485 A2 BR PI0907485A2
Authority
BR
Brazil
Prior art keywords
antigen
binding polypeptides
cartilage degeneration
polypeptides against
against cartilage
Prior art date
Application number
BRPI0907485-6A
Other languages
English (en)
Portuguese (pt)
Inventor
David Urech
Peter Lichtlen
Original Assignee
Delenex Therapeutics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delenex Therapeutics Ag filed Critical Delenex Therapeutics Ag
Publication of BRPI0907485A2 publication Critical patent/BRPI0907485A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0907485-6A 2008-02-05 2009-02-05 Polipeptídeos de ligação a antígeno contra degeneração de cartilagem BRPI0907485A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2631708P 2008-02-05 2008-02-05
US8887608P 2008-08-14 2008-08-14
PCT/CH2009/000045 WO2009097704A1 (en) 2008-02-05 2009-02-05 Antigen-binding polypeptides against cartilage degeneration

Publications (1)

Publication Number Publication Date
BRPI0907485A2 true BRPI0907485A2 (pt) 2015-08-04

Family

ID=40568129

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0907485-6A BRPI0907485A2 (pt) 2008-02-05 2009-02-05 Polipeptídeos de ligação a antígeno contra degeneração de cartilagem

Country Status (10)

Country Link
US (1) US20110002927A1 (enExample)
EP (1) EP2240515A1 (enExample)
JP (1) JP2011510667A (enExample)
CN (1) CN101939335B (enExample)
AU (1) AU2009212079B2 (enExample)
BR (1) BRPI0907485A2 (enExample)
CA (1) CA2712965A1 (enExample)
IL (1) IL206720A0 (enExample)
RU (1) RU2010136988A (enExample)
WO (1) WO2009097704A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013540757A (ja) 2010-09-24 2013-11-07 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド カプセル化された作用物質の放出を制御する能力を有するナノ構造ゲル
CN104231086B (zh) * 2013-08-27 2019-12-13 北京韩美药品有限公司 双功能融合蛋白及其制备方法和用途
SG11201604227XA (en) * 2013-12-13 2016-07-28 Mercury Asset Man Co Ltd Articular cartilage imaging composition
EP3978022A1 (en) * 2016-05-06 2022-04-06 The Brigham and Women's Hospital, Inc. Binary self assembled gels for controlled delivery of encapsulated agents to cartilage
US11839605B2 (en) 2018-10-11 2023-12-12 Alivio Therapeutics, Inc. Non-injectable hydrogel formulations for smart release

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0013810D0 (en) * 2000-06-06 2000-07-26 Celltech Chiroscience Ltd Biological products
ES2424042T3 (es) * 2005-06-07 2013-09-26 Esbatech - A Novartis Company Llc Anticuerpos estables y solubles que inhiben TNF±
EP3093026B1 (en) * 2006-07-10 2020-07-01 ESBATech, an Alcon Biomedical Research Unit LLC Scfv antibodies which pass epithelial and/or endothelial layers

Also Published As

Publication number Publication date
CA2712965A1 (en) 2009-08-13
JP2011510667A (ja) 2011-04-07
CN101939335B (zh) 2015-02-11
EP2240515A1 (en) 2010-10-20
WO2009097704A1 (en) 2009-08-13
AU2009212079B2 (en) 2012-08-30
RU2010136988A (ru) 2012-03-20
CN101939335A (zh) 2011-01-05
US20110002927A1 (en) 2011-01-06
AU2009212079A1 (en) 2009-08-13
IL206720A0 (en) 2010-12-30

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]