JP2011510667A - 軟骨変性に対する抗原結合性ポリペプチド - Google Patents
軟骨変性に対する抗原結合性ポリペプチド Download PDFInfo
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2631708P | 2008-02-05 | 2008-02-05 | |
| US8887608P | 2008-08-14 | 2008-08-14 | |
| PCT/CH2009/000045 WO2009097704A1 (en) | 2008-02-05 | 2009-02-05 | Antigen-binding polypeptides against cartilage degeneration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011510667A true JP2011510667A (ja) | 2011-04-07 |
| JP2011510667A5 JP2011510667A5 (enExample) | 2013-01-24 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015087839A1 (ja) * | 2013-12-13 | 2015-06-18 | Ｍｍｉｐマネジメント株式会社 | 関節軟骨イメージング組成物 |
| JP2019514957A (ja) * | 2016-05-06 | 2019-06-06 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． | 軟骨へのカプセル化薬剤の制御送達のための二成分型自己集合ゲル |
| US11672864B2 (en) | 2010-09-24 | 2023-06-13 | The Brigham And Women's Hospital, Inc. | Nanostructured gels capable of controlled release of encapsulated agents |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104231086B (zh) * | 2013-08-27 | 2019-12-13 | 北京韩美药品有限公司 | 双功能融合蛋白及其制备方法和用途 |
| US11839605B2 (en) | 2018-10-11 | 2023-12-12 | Alivio Therapeutics, Inc. | Non-injectable hydrogel formulations for smart release |
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| WO2006131013A2 (en) * | 2005-06-07 | 2006-12-14 | Esbatech Ag | STABLE AND SOLUBLE ANTIBODIES INHIBITING TNFα |
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| GB0013810D0 (en) * | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
| EP3093026B1 (en) * | 2006-07-10 | 2020-07-01 | ESBATech, an Alcon Biomedical Research Unit LLC | Scfv antibodies which pass epithelial and/or endothelial layers |
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| WO2006131013A2 (en) * | 2005-06-07 | 2006-12-14 | Esbatech Ag | STABLE AND SOLUBLE ANTIBODIES INHIBITING TNFα |
Non-Patent Citations (1)
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| JPN6013030220; Ｊ． Ａｎａｔ． Ｖｏｌ．１２２， Ｎｏ．２, 1976, ｐｐ．３３５-３４７ * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11672864B2 (en) | 2010-09-24 | 2023-06-13 | The Brigham And Women's Hospital, Inc. | Nanostructured gels capable of controlled release of encapsulated agents |
| WO2015087839A1 (ja) * | 2013-12-13 | 2015-06-18 | Ｍｍｉｐマネジメント株式会社 | 関節軟骨イメージング組成物 |
| US10143762B2 (en) | 2013-12-13 | 2018-12-04 | Mercury Assel Management Co., Ltd. | Articular cartilage imaging composition |
| JP2019514957A (ja) * | 2016-05-06 | 2019-06-06 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． | 軟骨へのカプセル化薬剤の制御送達のための二成分型自己集合ゲル |
| JP7169880B2 (ja) | 2016-05-06 | 2022-11-11 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 軟骨へのカプセル化薬剤の制御送達のための二成分型自己集合ゲル |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2712965A1 (en) | 2009-08-13 |
| CN101939335B (zh) | 2015-02-11 |
| EP2240515A1 (en) | 2010-10-20 |
| WO2009097704A1 (en) | 2009-08-13 |
| BRPI0907485A2 (pt) | 2015-08-04 |
| AU2009212079B2 (en) | 2012-08-30 |
| RU2010136988A (ru) | 2012-03-20 |
| CN101939335A (zh) | 2011-01-05 |
| US20110002927A1 (en) | 2011-01-06 |
| AU2009212079A1 (en) | 2009-08-13 |
| IL206720A0 (en) | 2010-12-30 |
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