BRPI0813428A2 - Óperon recombinante, método para produzir uma célula hospedeira, composição de vacina contra diarréia, e, uso de um óperon - Google Patents

Óperon recombinante, método para produzir uma célula hospedeira, composição de vacina contra diarréia, e, uso de um óperon

Info

Publication number
BRPI0813428A2
BRPI0813428A2 BRPI0813428-6A2A BRPI0813428A BRPI0813428A2 BR PI0813428 A2 BRPI0813428 A2 BR PI0813428A2 BR PI0813428 A BRPI0813428 A BR PI0813428A BR PI0813428 A2 BRPI0813428 A2 BR PI0813428A2
Authority
BR
Brazil
Prior art keywords
host cell
opera
operon
disclosed
recombinant
Prior art date
Application number
BRPI0813428-6A2A
Other languages
English (en)
Inventor
Michael Lebens
Ann-Mari Svennerholm
Joshua Tobias
Original Assignee
Crucell Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crucell Sweden Ab filed Critical Crucell Sweden Ab
Publication of BRPI0813428A2 publication Critical patent/BRPI0813428A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0813428-6A2A 2007-07-02 2008-07-01 Óperon recombinante, método para produzir uma célula hospedeira, composição de vacina contra diarréia, e, uso de um óperon BRPI0813428A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07111501 2007-07-02
PCT/EP2008/058438 WO2009004002A1 (en) 2007-07-02 2008-07-01 Hybrid operon for expression of colonization factor (cf) antigens of enterotoxigenic escherichia coli

Publications (1)

Publication Number Publication Date
BRPI0813428A2 true BRPI0813428A2 (pt) 2014-12-23

Family

ID=39345431

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0813428-6A2A BRPI0813428A2 (pt) 2007-07-02 2008-07-01 Óperon recombinante, método para produzir uma célula hospedeira, composição de vacina contra diarréia, e, uso de um óperon

Country Status (11)

Country Link
US (1) US20100136059A1 (pt)
EP (1) EP2167664B1 (pt)
JP (1) JP2010531653A (pt)
KR (1) KR20100040847A (pt)
CN (1) CN101688211A (pt)
AT (1) ATE542905T1 (pt)
AU (1) AU2008270303A1 (pt)
BR (1) BRPI0813428A2 (pt)
CA (1) CA2691962A1 (pt)
MX (1) MX2009013260A (pt)
WO (1) WO2009004002A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014005601B1 (pt) * 2011-09-12 2020-09-29 Scandinavian Biopharma Holding Ab Vacina oral para a imunização contra a diarréia induzida pela etec
EP2897638A1 (en) 2012-09-24 2015-07-29 Montana State University-Bozeman Recombinant lactococcus lactis expressing escherichia coli colonization factor antigen i (cfa/i) fimbriae and their methods of use
AU2013345316B2 (en) 2012-11-19 2016-04-14 The United States Of America As Represented By The Secretary Of The Navy Recombinant polypeptide construct comprising multiple enterotoxigenic Escherichia coli fimbrial subunits
CA2966754A1 (en) 2014-11-05 2016-05-12 The United States Of America As Represented By The Secretary Of The Navy Synthetic antigen constructs against campylobacter jejuni
US10500261B2 (en) 2014-11-05 2019-12-10 The United States Of America As Represented By The Secretary Of The Navy Synthetic antigen constructs against campylobacter jejuni
CN106011163B (zh) * 2016-05-19 2020-02-04 武汉华美生物工程有限公司 一种无细胞表达信号蛋白的方法及表达系统
JP2021519789A (ja) * 2018-04-03 2021-08-12 ユニバーシティ オブ メリーランド，ボルチモア 増強された多価赤痢菌−毒素原性大腸菌ワクチン

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982003088A1 (en) * 1981-03-09 1982-09-16 Corp Cetus Vaccines
US7118758B1 (en) * 1997-01-24 2006-10-10 The United States Of America As Represented By The Secretary Of The Army Transformed bacteria producing CS6 antigens as vaccines
GB0121998D0 (en) * 2001-09-11 2001-10-31 Acambis Res Ltd Attenuated bacteria useful in vaccines
EP1543836A1 (en) * 2003-12-17 2005-06-22 Berna Biotech AG Recombinant Vibrio cholerae strain and vaccine comprising said strain
CN101378780A (zh) * 2006-02-01 2009-03-04 Sbl疫苗公司 重组细菌中的肠产毒性大肠杆菌定居因子(cf)抗原

Also Published As

Publication number Publication date
CA2691962A1 (en) 2009-01-08
US20100136059A1 (en) 2010-06-03
AU2008270303A1 (en) 2009-01-08
KR20100040847A (ko) 2010-04-21
ATE542905T1 (de) 2012-02-15
WO2009004002A1 (en) 2009-01-08
MX2009013260A (es) 2010-01-25
EP2167664A1 (en) 2010-03-31
JP2010531653A (ja) 2010-09-30
CN101688211A (zh) 2010-03-31
EP2167664B1 (en) 2012-01-25

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.