BRPI0808353B8 - usos de amidas do ácido 3-aril-3-hidróxi-2-amino-propiônico, amidas do ácido 3-heteroaril-3-hidróxi-2-amino-propiônico e compostos relacionados - Google Patents
usos de amidas do ácido 3-aril-3-hidróxi-2-amino-propiônico, amidas do ácido 3-heteroaril-3-hidróxi-2-amino-propiônico e compostos relacionadosInfo
- Publication number
- BRPI0808353B8 BRPI0808353B8 BRPI0808353A BRPI0808353A BRPI0808353B8 BR PI0808353 B8 BRPI0808353 B8 BR PI0808353B8 BR PI0808353 A BRPI0808353 A BR PI0808353A BR PI0808353 A BRPI0808353 A BR PI0808353A BR PI0808353 B8 BRPI0808353 B8 BR PI0808353B8
- Authority
- BR
- Brazil
- Prior art keywords
- hydroxy
- amino
- propionic acid
- acid amides
- heteroaryl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Quinoline Compounds (AREA)
- Furan Compounds (AREA)
Abstract
usos de amidas do ácido 3-aril-3-hidróxi-2-amino-propiônico, amidas do ácido 3-heteroaril-3-hidróxi-2-amino-propiônico e compostos relacionados. a presente invenção refere-se a usos de compostos de fórmulas 1 e 2 fórmula 1 nas quais as variáveis têm os significados descritos na especificação, para a fabricação de medicamentos para o tratamento de um paciente que sofre de um distúrbio cognitivo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89319607P | 2007-03-06 | 2007-03-06 | |
US60/893,196 | 2007-03-06 | ||
PCT/US2008/055812 WO2008109610A1 (en) | 2007-03-06 | 2008-03-04 | Methods for treating cognitive disorders using 3-aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0808353A2 BRPI0808353A2 (pt) | 2014-07-29 |
BRPI0808353B1 BRPI0808353B1 (pt) | 2020-03-31 |
BRPI0808353B8 true BRPI0808353B8 (pt) | 2021-05-25 |
Family
ID=39535350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0808353A BRPI0808353B8 (pt) | 2007-03-06 | 2008-03-04 | usos de amidas do ácido 3-aril-3-hidróxi-2-amino-propiônico, amidas do ácido 3-heteroaril-3-hidróxi-2-amino-propiônico e compostos relacionados |
Country Status (12)
Country | Link |
---|---|
US (1) | US8623891B2 (pt) |
EP (2) | EP2131837B1 (pt) |
JP (1) | JP2010520299A (pt) |
AU (3) | AU2008222890C1 (pt) |
BR (1) | BRPI0808353B8 (pt) |
CA (1) | CA2680324A1 (pt) |
DK (1) | DK2481407T3 (pt) |
ES (2) | ES2383384T3 (pt) |
HK (1) | HK1139855A1 (pt) |
PT (1) | PT2481407T (pt) |
TR (1) | TR201818771T4 (pt) |
WO (1) | WO2008109610A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5042040B2 (ja) | 2005-01-26 | 2012-10-03 | アラーガン、インコーポレイテッド | 鎮痛活性および/または免疫賦活活性を有する1−アリール−1−ヒドロキシ−2,3−ジアミノ−プロピルアミン、1−ヘテロアリール−1−ヒドロキシ−2,3−ジアミノ−プロピルアミンおよび関連化合物 |
EP2175850B1 (en) * | 2007-07-17 | 2017-01-11 | Allergan, Inc. | Treatment of anxiety |
KR101757003B1 (ko) | 2009-07-17 | 2017-07-11 | 알러간, 인코포레이티드 | 인지 장애를 치료하기 위한 콜린에스테라아제 저해물질을 포함한 조성물 |
AU2010295703A1 (en) * | 2009-09-16 | 2012-04-12 | Allergan, Inc. | Compositions and methods for treating seizure disorders |
EP2477622B1 (en) | 2009-09-16 | 2014-08-20 | Allergan, Inc. | Pharmaceutical composition for the treatment of spasticity |
JP2013505247A (ja) * | 2009-09-16 | 2013-02-14 | アラーガン インコーポレイテッド | 消化管運動障害を治療するための組成物および方法 |
HUE036381T2 (hu) * | 2013-08-15 | 2018-07-30 | Allergan Inc | (-)-(2R,3S)-2-amino-3-hidroxi-3-piridin-4-il-1-pirrolidin-1-il-propán-1-on (L)-(+) tartarát só, eljárás annak elõállítására és alkalmazása |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62114946A (ja) | 1985-11-13 | 1987-05-26 | Banyu Pharmaceut Co Ltd | フエニルセリンアミド誘導体およびそれを有効成分とする中枢神経系用剤 |
WO1997010817A1 (en) | 1995-09-20 | 1997-03-27 | The Regents Of The University Of Michigan | Amino ceramide-like compounds and therapeutic methods of use |
NO965193L (no) | 1995-12-08 | 1997-06-09 | Seikagaku Kogyo Kk Seikagaku C | Aminalkoholderivat og fremgangsmåte for fremstilling derav |
GB9909064D0 (en) * | 1999-04-20 | 1999-06-16 | Oxford Glycosciences Uk Ltd | Therapies |
SE9904197D0 (sv) | 1999-11-22 | 1999-11-22 | Amersham Pharm Biotech Ab | A method for anion exchange adsorption on matrices carrying mixed mode ligands |
ATE554082T1 (de) * | 2001-07-16 | 2012-05-15 | Genzyme Corp | N-acetylsphingosin glukosyltransferase inhibitor |
US6835831B2 (en) | 2001-11-26 | 2004-12-28 | Genzyme Corporation | Diastereoselective synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors |
US20050101674A1 (en) | 2003-11-12 | 2005-05-12 | Maurer Barry J. | PPMP as a ceramide catabolism inhibitor for cancer treatment |
US20060081273A1 (en) * | 2004-10-20 | 2006-04-20 | Mcdermott Wayne T | Dense fluid compositions and processes using same for article treatment and residue removal |
JP5042040B2 (ja) * | 2005-01-26 | 2012-10-03 | アラーガン、インコーポレイテッド | 鎮痛活性および/または免疫賦活活性を有する1−アリール−1−ヒドロキシ−2,3−ジアミノ−プロピルアミン、1−ヘテロアリール−1−ヒドロキシ−2,3−ジアミノ−プロピルアミンおよび関連化合物 |
WO2008011485A2 (en) | 2006-07-19 | 2008-01-24 | Allergan, Inc. | Methods for treating chronic pain |
WO2008011483A2 (en) | 2006-07-19 | 2008-01-24 | Allergan, Inc. | Methods for treating chronic pain using 1- (hetero) aryl-1-hydroxy 2,3-diamino-propyl amines and related compounds |
-
2008
- 2008-03-04 PT PT12151551T patent/PT2481407T/pt unknown
- 2008-03-04 WO PCT/US2008/055812 patent/WO2008109610A1/en active Application Filing
- 2008-03-04 ES ES08731362T patent/ES2383384T3/es active Active
- 2008-03-04 CA CA002680324A patent/CA2680324A1/en not_active Abandoned
- 2008-03-04 EP EP08731362A patent/EP2131837B1/en active Active
- 2008-03-04 EP EP12151551.4A patent/EP2481407B1/en active Active
- 2008-03-04 JP JP2009552838A patent/JP2010520299A/ja active Pending
- 2008-03-04 TR TR2018/18771T patent/TR201818771T4/tr unknown
- 2008-03-04 AU AU2008222890A patent/AU2008222890C1/en active Active
- 2008-03-04 ES ES12151551T patent/ES2711075T3/es active Active
- 2008-03-04 US US12/530,124 patent/US8623891B2/en active Active
- 2008-03-04 DK DK12151551.4T patent/DK2481407T3/en active
- 2008-03-04 BR BRPI0808353A patent/BRPI0808353B8/pt active IP Right Grant
-
2010
- 2010-06-15 HK HK10105998.9A patent/HK1139855A1/xx not_active IP Right Cessation
-
2016
- 2016-06-24 AU AU2016204334A patent/AU2016204334B2/en active Active
-
2018
- 2018-06-15 AU AU2018204290A patent/AU2018204290B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2131837B1 (en) | 2012-05-16 |
TR201818771T4 (tr) | 2019-01-21 |
WO2008109610A1 (en) | 2008-09-12 |
ES2711075T3 (es) | 2019-04-30 |
AU2008222890B2 (en) | 2016-03-31 |
BRPI0808353B1 (pt) | 2020-03-31 |
AU2008222890A1 (en) | 2008-09-12 |
HK1139855A1 (en) | 2010-09-30 |
EP2481407B1 (en) | 2018-09-26 |
JP2010520299A (ja) | 2010-06-10 |
DK2481407T3 (en) | 2019-01-07 |
US20100093793A1 (en) | 2010-04-15 |
AU2008222890C1 (en) | 2016-09-08 |
BRPI0808353A2 (pt) | 2014-07-29 |
PT2481407T (pt) | 2018-12-28 |
AU2016204334A1 (en) | 2016-07-14 |
AU2018204290A1 (en) | 2018-07-05 |
EP2131837A1 (en) | 2009-12-16 |
CA2680324A1 (en) | 2008-09-12 |
US8623891B2 (en) | 2014-01-07 |
AU2016204334B2 (en) | 2018-03-15 |
AU2018204290B2 (en) | 2020-05-21 |
EP2481407A1 (en) | 2012-08-01 |
ES2383384T3 (es) | 2012-06-20 |
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