BRPI0807749A2 - Composto, composição farmacêutica, e, método para a prevenção, tratamento ou melhora de doenças ou condições dérmicas, ou distúrbios de ferida cutânea agudos ou crônicos. - Google Patents
Composto, composição farmacêutica, e, método para a prevenção, tratamento ou melhora de doenças ou condições dérmicas, ou distúrbios de ferida cutânea agudos ou crônicos.Info
- Publication number
- BRPI0807749A2 BRPI0807749A2 BRPI0807749-5A2A BRPI0807749A BRPI0807749A2 BR PI0807749 A2 BRPI0807749 A2 BR PI0807749A2 BR PI0807749 A BRPI0807749 A BR PI0807749A BR PI0807749 A2 BRPI0807749 A2 BR PI0807749A2
- Authority
- BR
- Brazil
- Prior art keywords
- cutaneal
- chronic
- acute
- prevention
- improvement
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90384907P | 2007-02-28 | 2007-02-28 | |
| US60/903849 | 2007-02-28 | ||
| US94684907P | 2007-06-28 | 2007-06-28 | |
| US60/946849 | 2007-06-28 | ||
| PCT/DK2008/000080 WO2008104175A2 (en) | 2007-02-28 | 2008-02-26 | Novel phosphodiesterase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0807749A2 true BRPI0807749A2 (pt) | 2014-06-17 |
| BRPI0807749B1 BRPI0807749B1 (pt) | 2021-01-05 |
| BRPI0807749B8 BRPI0807749B8 (pt) | 2022-09-06 |
Family
ID=39415336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0807749A BRPI0807749B8 (pt) | 2007-02-28 | 2008-02-26 | composto, composição farmacêutica, e, método para a prevenção, tratamento ou melhora de doenças ou condições dérmicas, ou distúrbios de ferida cutânea agudos ou crônicos |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8338431B2 (pt) |
| EP (1) | EP2114951B9 (pt) |
| JP (1) | JP5501770B2 (pt) |
| KR (1) | KR101571654B1 (pt) |
| AU (1) | AU2008221121B2 (pt) |
| BR (1) | BRPI0807749B8 (pt) |
| CA (1) | CA2676933C (pt) |
| CY (1) | CY1115227T1 (pt) |
| DK (1) | DK2114951T3 (pt) |
| ES (1) | ES2478670T3 (pt) |
| HR (1) | HRP20140585T1 (pt) |
| IL (1) | IL200153A (pt) |
| MX (1) | MX2009009238A (pt) |
| MY (1) | MY150075A (pt) |
| NZ (1) | NZ578804A (pt) |
| PL (1) | PL2114951T3 (pt) |
| PT (1) | PT2114951E (pt) |
| RS (1) | RS53407B (pt) |
| RU (1) | RU2495043C2 (pt) |
| SI (1) | SI2114951T1 (pt) |
| WO (1) | WO2008104175A2 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010335656B2 (en) | 2009-12-22 | 2015-05-07 | Leo Pharma A/S | Pharmaceutical composition comprising solvent mixture and a vitamin D derivative or analogue |
| JP5816194B2 (ja) | 2009-12-22 | 2015-11-18 | レオ ファーマ アクティーゼルスカブ | カルシポトリオール一水和物ナノクリスタル |
| MX2012007229A (es) | 2009-12-22 | 2012-07-30 | Leo Pharma As | Composicion cutanea que comprende analogo de vitamina d y mezcla de solvente y tensioactivos. |
| US8980905B2 (en) | 2010-06-24 | 2015-03-17 | Leo Pharma A/S | Benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors |
| US20160022681A1 (en) * | 2012-02-14 | 2016-01-28 | University Of Rochester | Methods of increasing lymphatic transport |
| IN2014DN10239A (pt) * | 2012-06-04 | 2015-08-07 | Chiesi Farma Spa | |
| CN104822392B (zh) * | 2012-11-30 | 2017-09-08 | 利奥制药有限公司 | 抑制活化的t‑细胞中il‑22表达的方法 |
| DK3157930T3 (en) * | 2014-06-23 | 2019-01-21 | Leo Pharma As | PROCEDURES FOR THE PREPARATION OF HETEROCYCLIC 1,3-BENZODIOXOL COMPOUNDS |
| ES2762987T3 (es) | 2015-06-19 | 2020-05-26 | Bristol Myers Squibb Co | Macrociclos de diamida como inhibidores del factor XIA |
| CN114085234B (zh) * | 2015-12-18 | 2024-12-17 | 联合疗法公司 | 用于制备1,3-苯并间二氧杂环戊烯杂环化合物的方法 |
| EP3551633B1 (en) * | 2016-12-12 | 2021-03-31 | Leo Pharma A/S | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors |
| WO2018108231A1 (en) * | 2016-12-12 | 2018-06-21 | Leo Pharma A/S | Substituted pyrazoloazepin-8-ones and their use as phosphodiesterase inhibitors |
| US11065257B2 (en) * | 2016-12-12 | 2021-07-20 | Leo Pharma A/S | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors |
| DK3642210T3 (da) | 2017-06-20 | 2024-12-09 | Union Therapeutics As | Fremgangsmåder til fremstilling af heterocykliske 1,3-benzodioxolforbindelser |
| TW201919682A (zh) | 2017-08-08 | 2019-06-01 | 西班牙商阿爾米雷爾有限公司 | 活化Nrf2路徑的新穎化合物 |
| JP7203846B2 (ja) | 2017-12-15 | 2023-01-13 | ユニオン・セラピューティクス・アクティエセルスカブ | 置換アゼチジンジヒドロチエノピリジンおよびホスホジエステラーゼ阻害剤としてのそれらの使用 |
| GB202306662D0 (en) | 2023-05-05 | 2023-06-21 | Union Therapeutics As | Dosage regimen |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9507297D0 (en) | 1995-04-07 | 1995-05-31 | Rh Ne Poulenc Rorer Limited | New composition of matter |
| US6514996B2 (en) * | 1995-05-19 | 2003-02-04 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of benzofuran or benzodioxole |
| CN1163493C (zh) | 1995-05-19 | 2004-08-25 | 协和发酵工业株式会社 | 含氧杂环化合物 |
| CZ371998A3 (cs) * | 1996-05-20 | 1999-03-17 | Darwin Discovery Limited | Benzofuranové karboxamidy a jejich terapeutické použití |
| DK0927183T3 (da) * | 1996-08-28 | 2004-11-29 | Procter & Gamble | Spirocykliske metalloprotease-inhibitorer |
| AU4967697A (en) * | 1996-11-19 | 1998-06-10 | Kyowa Hakko Kogyo Co. Ltd. | Oxygenic heterocyclic compounds |
| ATE237612T1 (de) | 1997-10-01 | 2003-05-15 | Kyowa Hakko Kogyo Kk | Benzofuranderivate |
-
2008
- 2008-02-26 ES ES08706922.5T patent/ES2478670T3/es active Active
- 2008-02-26 HR HRP20140585AT patent/HRP20140585T1/hr unknown
- 2008-02-26 BR BRPI0807749A patent/BRPI0807749B8/pt not_active IP Right Cessation
- 2008-02-26 NZ NZ578804A patent/NZ578804A/en not_active IP Right Cessation
- 2008-02-26 SI SI200831224T patent/SI2114951T1/sl unknown
- 2008-02-26 MY MYPI20093168A patent/MY150075A/en unknown
- 2008-02-26 CA CA2676933A patent/CA2676933C/en active Active
- 2008-02-26 RS RS20140365A patent/RS53407B/sr unknown
- 2008-02-26 US US12/528,649 patent/US8338431B2/en active Active
- 2008-02-26 JP JP2009551915A patent/JP5501770B2/ja not_active Expired - Fee Related
- 2008-02-26 EP EP08706922.5A patent/EP2114951B9/en active Active
- 2008-02-26 PL PL08706922T patent/PL2114951T3/pl unknown
- 2008-02-26 PT PT87069225T patent/PT2114951E/pt unknown
- 2008-02-26 KR KR1020097018073A patent/KR101571654B1/ko active Active
- 2008-02-26 AU AU2008221121A patent/AU2008221121B2/en not_active Ceased
- 2008-02-26 WO PCT/DK2008/000080 patent/WO2008104175A2/en not_active Ceased
- 2008-02-26 DK DK08706922.5T patent/DK2114951T3/da active
- 2008-02-26 RU RU2009135810/04A patent/RU2495043C2/ru active
- 2008-02-26 MX MX2009009238A patent/MX2009009238A/es active IP Right Grant
-
2009
- 2009-07-30 IL IL200153A patent/IL200153A/en active IP Right Grant
-
2014
- 2014-06-17 CY CY20141100437T patent/CY1115227T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1115227T1 (el) | 2017-01-04 |
| HRP20140585T1 (hr) | 2014-09-12 |
| AU2008221121B2 (en) | 2013-10-03 |
| BRPI0807749B8 (pt) | 2022-09-06 |
| US8338431B2 (en) | 2012-12-25 |
| PT2114951E (pt) | 2014-07-17 |
| ES2478670T3 (es) | 2014-07-22 |
| MX2009009238A (es) | 2009-09-08 |
| BRPI0807749B1 (pt) | 2021-01-05 |
| JP5501770B2 (ja) | 2014-05-28 |
| IL200153A (en) | 2016-11-30 |
| AU2008221121A1 (en) | 2008-09-04 |
| HK1138262A1 (en) | 2010-08-20 |
| EP2114951A2 (en) | 2009-11-11 |
| CA2676933C (en) | 2015-09-29 |
| EP2114951B9 (en) | 2015-09-02 |
| PL2114951T3 (pl) | 2014-10-31 |
| NZ578804A (en) | 2012-04-27 |
| RU2495043C2 (ru) | 2013-10-10 |
| RS53407B (sr) | 2014-10-31 |
| KR20090126252A (ko) | 2009-12-08 |
| KR101571654B1 (ko) | 2015-11-25 |
| US20100099688A1 (en) | 2010-04-22 |
| MY150075A (en) | 2013-11-29 |
| JP2010519332A (ja) | 2010-06-03 |
| CA2676933A1 (en) | 2008-09-04 |
| IL200153A0 (en) | 2010-04-15 |
| RU2009135810A (ru) | 2011-04-10 |
| SI2114951T1 (sl) | 2014-08-29 |
| WO2008104175A3 (en) | 2009-01-29 |
| EP2114951B1 (en) | 2014-04-09 |
| WO2008104175A2 (en) | 2008-09-04 |
| DK2114951T3 (da) | 2014-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/01/2021, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/02/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
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| B25A | Requested transfer of rights approved |
Owner name: UNION THERAPEUTICS A/S (DK) |
|
| B25L | Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled |
Owner name: LEO PHARMA A/S (DK) Free format text: ANULADA A PUBLICACAO CODIGO 25.1 NA RPI NO 2671 DE 15/03/2022 POR TER SIDO INDEVIDA. |
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| B25A | Requested transfer of rights approved |
Owner name: UNION THERAPEUTICS A/S (DK) |
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| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 18A ANUIDADE. |