BRPI0807291A2 - "polinucleotídeo isolado, polipeptídeo, construção de dna recombinante, célula vegetal, métodos para transformar uma célula vegetal, para produzir um vegetal transformado, sementes transgênicas, óleos ou subprodutos, métodos para produção de ácidos graxos poliinsaturados de cadeia longa em uma célula vegetal, de pelo menos um ácido graxo poliinsaturado em uma célula vegetal de semente oleaginosa, plantas de semente oleaginosa, sementes transgênicas, produtos alimentícios ou rações e progênies de vegetais - Google Patents
"polinucleotídeo isolado, polipeptídeo, construção de dna recombinante, célula vegetal, métodos para transformar uma célula vegetal, para produzir um vegetal transformado, sementes transgênicas, óleos ou subprodutos, métodos para produção de ácidos graxos poliinsaturados de cadeia longa em uma célula vegetal, de pelo menos um ácido graxo poliinsaturado em uma célula vegetal de semente oleaginosa, plantas de semente oleaginosa, sementes transgênicas, produtos alimentícios ou rações e progênies de vegetaisInfo
- Publication number
- BRPI0807291A2 BRPI0807291A2 BRPI0807291-4A2A BRPI0807291A BRPI0807291A2 BR PI0807291 A2 BRPI0807291 A2 BR PI0807291A2 BR PI0807291 A BRPI0807291 A BR PI0807291A BR PI0807291 A2 BRPI0807291 A2 BR PI0807291A2
- Authority
- BR
- Brazil
- Prior art keywords
- vegetable
- transgenic seeds
- vegetable cell
- inputduces
- gradesous
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings or cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Animal Husbandry (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91192507P | 2007-04-16 | 2007-04-16 | |
| PCT/US2008/060393 WO2008128240A1 (en) | 2007-04-16 | 2008-04-16 | Delta 9 elongases and their use in making polyunsaturated fatty acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0807291A2 true BRPI0807291A2 (pt) | 2014-04-29 |
Family
ID=39619289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0807291-4A2A BRPI0807291A2 (pt) | 2007-04-16 | 2008-04-16 | "polinucleotídeo isolado, polipeptídeo, construção de dna recombinante, célula vegetal, métodos para transformar uma célula vegetal, para produzir um vegetal transformado, sementes transgênicas, óleos ou subprodutos, métodos para produção de ácidos graxos poliinsaturados de cadeia longa em uma célula vegetal, de pelo menos um ácido graxo poliinsaturado em uma célula vegetal de semente oleaginosa, plantas de semente oleaginosa, sementes transgênicas, produtos alimentícios ou rações e progênies de vegetais |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US8119860B2 (enExample) |
| EP (2) | EP2134837B1 (enExample) |
| JP (1) | JP5501954B2 (enExample) |
| CN (1) | CN101848996B (enExample) |
| AU (2) | AU2008240028B2 (enExample) |
| BR (1) | BRPI0807291A2 (enExample) |
| CA (2) | CA2682962A1 (enExample) |
| DK (1) | DK2137304T3 (enExample) |
| WO (2) | WO2008128241A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2529572T3 (es) | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
| PL1756280T3 (pl) | 2004-04-22 | 2015-04-30 | Commw Scient Ind Res Org | Synteza długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach rekombinowanych |
| BRPI0716075A2 (pt) | 2006-08-29 | 2013-08-06 | Commw Scient Ind Res Org | sÍntese de Ácidos graxos |
| US8119860B2 (en) * | 2007-04-16 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| US8110388B2 (en) * | 2007-05-25 | 2012-02-07 | Suntory Holdings Limited | Lysophosphatidic acid acyltransferase genes |
| US8168858B2 (en) | 2008-06-20 | 2012-05-01 | E. I. Du Pont De Nemours And Company | Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids |
| CA3015426C (en) | 2008-11-18 | 2020-01-14 | Commonwealth Scientific And Industrial Research Organisation | Recombinant cells comprising exogenous .delta.5 and .delta.6 desaturases, .delta.5 and .delta.6 elongases, and .delta.4 desaturases |
| CA2744716C (en) * | 2008-12-18 | 2017-05-23 | E.I. Du Pont De Nemours And Company | Reducing byproduction of malonates in a fermentation process |
| WO2010147907A1 (en) | 2009-06-16 | 2010-12-23 | E. I. Du Pont De Nemours And Company | High eicosapentaenoic acid oils from improved optimized strains of yarrowia lipolytica |
| US8188335B2 (en) | 2009-07-17 | 2012-05-29 | Abbott Laboratories | Δ9-elongase for production of polyunsaturated fatty acid-enriched oils |
| JP6476436B2 (ja) | 2009-11-03 | 2019-03-06 | ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. | 細胞および少なくとも20個の炭素原子を有する多価不飽和脂肪酸(lc−pufa)を含んでなる組成物 |
| AU2010317140B2 (en) | 2009-11-03 | 2016-04-21 | Dsm Ip Assets B.V. | Vegatable oil comprising a polyunsaturaded fatty acid having at least 20 carbon atoms |
| CN103282474A (zh) | 2010-04-22 | 2013-09-04 | 纳幕尔杜邦公司 | 从微生物生物质中获得包含多不饱和脂肪酸的组合物的方法 |
| US8703473B2 (en) | 2010-08-26 | 2014-04-22 | E I Du Pont De Nemours And Company | Recombinant microbial host cells for high eicosapentaenoic acid production |
| WO2012027676A1 (en) | 2010-08-26 | 2012-03-01 | E. I. Du Pont De Nemours And Company | Mutant delta-9 elongases and their use in making polyunsaturated fatty acids |
| AU2011293189B2 (en) | 2010-08-26 | 2017-02-16 | E. I. Du Pont De Nemours And Company | Mutant HPGG motif and HDASH motif delta-5 desaturases and their use in making polyunsaturated fatty acids |
| BR112013016769A2 (pt) | 2010-12-30 | 2016-10-11 | Du Pont | yarrowia lipolytica transformada e método para produzir pelo menos um produto não nativo de interesse |
| US20130040340A1 (en) | 2011-02-07 | 2013-02-14 | E. I. Du Pont De Nemours And Company | Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms |
| HUE033766T2 (en) | 2012-06-15 | 2018-01-29 | Commw Scient Ind Res Org | Production of long chain polyunsaturated fatty acids in plant cells |
| CA2892516A1 (en) | 2012-12-21 | 2014-06-26 | E. I. Du Pont De Nemours And Company | Down-regulation of a polynucleotide encoding a sou2 sorbitol utilization protein to modify lipid production in microbial cells |
| US20160272997A1 (en) | 2013-10-25 | 2016-09-22 | Pioneer Hi-Bred International, Inc. | Stem canker tolerant soybeans and methods of use |
| EA037817B1 (ru) | 2013-12-18 | 2021-05-25 | Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн | Экстрагированный растительный липид, содержащий длинноцепочечные полиненасыщенные жирные кислоты |
| CA2953008C (en) | 2014-06-27 | 2024-03-19 | Nuseed Pty Ltd | Lipid comprising docosapentaenoic acid |
| CN106916796B (zh) * | 2015-12-28 | 2021-06-29 | 丰益(上海)生物技术研发中心有限公司 | 裂殖壶菌delta-12脂肪酸脱饱和酶相关序列及其应用 |
| US11096344B2 (en) | 2016-02-05 | 2021-08-24 | Pioneer Hi-Bred International, Inc. | Genetic loci associated with brown stem rot resistance in soybean and methods of use |
| US20200015500A1 (en) | 2016-12-15 | 2020-01-16 | Dsm Ip Assets B.V. | Blend formulation comprising silicate and microbial and / or plant cells comprising a polyunsaturated fatty acid having at least 20 carbon atoms (lc-pufa) |
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| US4670285A (en) | 1982-08-06 | 1987-06-02 | The University Of Toronto Innovations Foundation | Infant formula |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5107065A (en) | 1986-03-28 | 1992-04-21 | Calgene, Inc. | Anti-sense regulation of gene expression in plant cells |
| US5188958A (en) | 1986-05-29 | 1993-02-23 | Calgene, Inc. | Transformation and foreign gene expression in brassica species |
| US5004863B2 (en) | 1986-12-03 | 2000-10-17 | Agracetus | Genetic engineering of cotton plants and lines |
| JP2527340B2 (ja) | 1986-12-15 | 1996-08-21 | アプライド バイオシステムズ インコーポレイテッド | ロ―ダミン染料の5−及び6−スクシニミジルカルボキシレ―ト異性体 |
| US5416011A (en) | 1988-07-22 | 1995-05-16 | Monsanto Company | Method for soybean transformation and regeneration |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| AU1871492A (en) | 1991-03-29 | 1992-11-02 | Board Of Trustees Of The University Of Illinois, The | Production fo transgenic soybean plants |
| US6372965B1 (en) | 1992-11-17 | 2002-04-16 | E.I. Du Pont De Nemours And Company | Genes for microsomal delta-12 fatty acid desaturases and hydroxylases from plants |
| US5648564A (en) | 1995-12-21 | 1997-07-15 | Kemin Industries, Inc. | Process for the formation, isolation and purification of comestible xanthophyll crystals from plants |
| US6075183A (en) | 1997-04-11 | 2000-06-13 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
| US6432684B1 (en) | 1997-04-11 | 2002-08-13 | Abbott Laboratories | Human desaturase gene and uses thereof |
| US5968809A (en) | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| US5972664A (en) | 1997-04-11 | 1999-10-26 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| ATE297994T1 (de) | 1997-04-11 | 2005-07-15 | Calgene Llc | Verfahren und zusammensetzungen für die synthese von langkettigen, mehrfach ungesättigten fettsäuren in pflanzen. |
| US6051754A (en) | 1997-04-11 | 2000-04-18 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
| US6403349B1 (en) | 1998-09-02 | 2002-06-11 | Abbott Laboratories | Elongase gene and uses thereof |
| US6825017B1 (en) | 1998-12-07 | 2004-11-30 | Washington State University Research Foundation | Desaturases and methods of using them for synthesis of polyunsaturated fatty acids |
| CA2791961A1 (en) | 1998-12-07 | 2000-06-15 | Washington State University Research Foundation | Desaturases and methods of using them for synthesis of polyunsaturated fatty acids |
| ATE507300T1 (de) | 2000-06-23 | 2011-05-15 | Du Pont | Rekombinante konstrukte und ihre verwendung bei der reduzierung der genexpression |
| ATE360075T1 (de) | 2000-07-21 | 2007-05-15 | Du Pont | Ein mit der synthese von delta-12 epoxy-gruppen in fettsäuren von pflanzen assoziiertes cytochrom p450 enzym |
| EP1395108B1 (en) * | 2001-03-16 | 2012-01-11 | BASF Plant Science GmbH | Sugar and lipid metabolism regulators in plants |
| GB0107510D0 (en) * | 2001-03-26 | 2001-05-16 | Univ Bristol | New elongase gene and a process for the production of -9-polyunsaturated fatty acids |
| TWI324181B (en) | 2001-04-16 | 2010-05-01 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US6797303B2 (en) | 2001-09-04 | 2004-09-28 | Lycored Natural Products Industries Ltd. | Carotenoid extraction process |
| BR0317304A (pt) | 2002-12-19 | 2005-11-08 | Univ Bristol | Processo para a produção de compostos, sequência de ácido nucleico isolada, sequência de aminoácidos, construção gênica, vetor, e, organismo |
| US20040172682A1 (en) | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
| US7129089B2 (en) | 2003-02-12 | 2006-10-31 | E. I. Du Pont De Nemours And Company | Annexin and P34 promoters and use in expression of transgenic genes in plants |
| US7238482B2 (en) | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| US7125672B2 (en) | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
| US7259255B2 (en) | 2003-06-25 | 2007-08-21 | E. I. Du Pont De Nemours And Company | Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast |
| PT2172536T (pt) | 2003-08-01 | 2016-08-17 | Basf Plant Science Gmbh | Processo para a produção de ácidos gordos poli-insaturados em organismos transgénicos |
| US20050132441A1 (en) | 2003-11-12 | 2005-06-16 | Damude Howard G. | Delta15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast |
| US7202356B2 (en) | 2003-11-14 | 2007-04-10 | E. I. Du Pont De Nemours And Company | Fructose-bisphosphate aldolase regulatory sequences for gene expression in oleaginous yeast |
| EP4219670A3 (de) | 2004-02-27 | 2023-08-09 | BASF Plant Science GmbH | Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen pflanzen |
| ES2529572T3 (es) | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
| PL1756280T3 (pl) | 2004-04-22 | 2015-04-30 | Commw Scient Ind Res Org | Synteza długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach rekombinowanych |
| US7550651B2 (en) | 2004-06-25 | 2009-06-23 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| US7465564B2 (en) | 2004-08-10 | 2008-12-16 | E.I. Du Pont De Nemours And Company | Production of γ-linolenic acid in oleaginous yeast |
| US7550286B2 (en) | 2004-11-04 | 2009-06-23 | E. I. Du Pont De Nemours And Company | Docosahexaenoic acid producing strains of Yarrowia lipolytica |
| WO2007061742A1 (en) | 2005-11-23 | 2007-05-31 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| US7465793B2 (en) * | 2006-04-20 | 2008-12-16 | E.I. Du Pont De Nemours And Company | Synthetic Δ17 desaturase derived from Phytophthora ramourum and its use in making polyunsaturated fatty acids |
| US7943823B2 (en) | 2006-04-28 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| US7678560B2 (en) | 2006-05-17 | 2010-03-16 | E.I. Du Pont De Nemours And Company | Δ 5 desaturase and its use in making polyunsaturated fatty acids |
| EP2121934A2 (en) | 2007-02-12 | 2009-11-25 | E. I. Du Pont de Nemours and Company | Production of arachidonic acid in oilseed plants |
| DK2129777T3 (en) * | 2007-04-03 | 2016-01-25 | Du Pont | MULTIZYMER AND USE THEREOF FOR THE PRODUCTION OF polyunsaturated fatty acids |
| US8188338B2 (en) * | 2007-04-10 | 2012-05-29 | E. I. Du Pont De Nemours And Company | Delta-8 desaturases and their use in making polyunsaturated fatty acids |
| US8119860B2 (en) | 2007-04-16 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| US8323935B2 (en) * | 2007-10-03 | 2012-12-04 | E I Du Pont De Nemours And Company | Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production |
| EP2274429B1 (en) * | 2008-04-03 | 2014-10-22 | E. I. du Pont de Nemours and Company | Multizymes |
| US9981108B2 (en) | 2009-10-30 | 2018-05-29 | Recor Medical, Inc. | Method and apparatus for treatment of hypertension through percutaneous ultrasound renal denervation |
| WO2015152822A1 (en) | 2014-03-31 | 2015-10-08 | Agency For Science, Technology And Research | Image processing devices and image processing methods |
-
2008
- 2008-04-15 US US12/102,979 patent/US8119860B2/en active Active
- 2008-04-15 US US12/102,879 patent/US7794701B2/en not_active Expired - Fee Related
- 2008-04-16 US US12/530,481 patent/US20100162435A1/en not_active Abandoned
- 2008-04-16 JP JP2010504199A patent/JP5501954B2/ja not_active Expired - Fee Related
- 2008-04-16 CA CA002682962A patent/CA2682962A1/en not_active Abandoned
- 2008-04-16 WO PCT/US2008/060396 patent/WO2008128241A1/en not_active Ceased
- 2008-04-16 CN CN2008800203954A patent/CN101848996B/zh not_active Expired - Fee Related
- 2008-04-16 EP EP08745901.2A patent/EP2134837B1/en not_active Not-in-force
- 2008-04-16 CA CA002679485A patent/CA2679485A1/en not_active Abandoned
- 2008-04-16 BR BRPI0807291-4A2A patent/BRPI0807291A2/pt not_active Application Discontinuation
- 2008-04-16 DK DK08745904.6T patent/DK2137304T3/da active
- 2008-04-16 AU AU2008240028A patent/AU2008240028B2/en active Active
- 2008-04-16 EP EP08745904.6A patent/EP2137304B1/en not_active Not-in-force
- 2008-04-16 WO PCT/US2008/060393 patent/WO2008128240A1/en not_active Ceased
- 2008-04-16 AU AU2008240029A patent/AU2008240029B2/en not_active Ceased
-
2010
- 2010-06-29 US US12/825,523 patent/US8298797B2/en not_active Expired - Fee Related
-
2012
- 2012-01-11 US US13/347,938 patent/US8377673B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2134837B1 (en) | 2014-01-01 |
| EP2134837A1 (en) | 2009-12-23 |
| US7794701B2 (en) | 2010-09-14 |
| CN101848996A (zh) | 2010-09-29 |
| AU2008240028B2 (en) | 2014-03-06 |
| CA2682962A1 (en) | 2008-10-23 |
| US20120100595A1 (en) | 2012-04-26 |
| WO2008128241A1 (en) | 2008-10-23 |
| US20100162435A1 (en) | 2010-06-24 |
| CA2679485A1 (en) | 2008-10-23 |
| US8119860B2 (en) | 2012-02-21 |
| US20080254522A1 (en) | 2008-10-16 |
| US20080254195A1 (en) | 2008-10-16 |
| US8298797B2 (en) | 2012-10-30 |
| US8377673B2 (en) | 2013-02-19 |
| JP5501954B2 (ja) | 2014-05-28 |
| US20100267098A1 (en) | 2010-10-21 |
| AU2008240029A1 (en) | 2008-10-23 |
| AU2008240029B2 (en) | 2013-05-02 |
| JP2010524468A (ja) | 2010-07-22 |
| WO2008128240A1 (en) | 2008-10-23 |
| DK2137304T3 (da) | 2013-11-11 |
| AU2008240028A1 (en) | 2008-10-23 |
| CN101848996B (zh) | 2013-05-29 |
| EP2137304A1 (en) | 2009-12-30 |
| EP2137304B1 (en) | 2013-08-14 |
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