BRPI0722361B8 - métodos para avaliar a concentração de um fármaco imunossupressor em uma amostra de sangue humano, composição de reagente de extração e kit de teste - Google Patents

métodos para avaliar a concentração de um fármaco imunossupressor em uma amostra de sangue humano, composição de reagente de extração e kit de teste

Info

Publication number
BRPI0722361B8
BRPI0722361B8 BRPI0722361A BRPI0722361A BRPI0722361B8 BR PI0722361 B8 BRPI0722361 B8 BR PI0722361B8 BR PI0722361 A BRPI0722361 A BR PI0722361A BR PI0722361 A BRPI0722361 A BR PI0722361A BR PI0722361 B8 BRPI0722361 B8 BR PI0722361B8
Authority
BR
Brazil
Prior art keywords
reagent composition
immunosuppressive drug
assessing
concentration
methods
Prior art date
Application number
BRPI0722361A
Other languages
English (en)
Inventor
C Grenier Frank
N Syed Hina
F Workman Ryan
Ali Salman
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BRPI0722361A2 publication Critical patent/BRPI0722361A2/pt
Publication of BRPI0722361A8 publication Critical patent/BRPI0722361A8/pt
Publication of BRPI0722361B1 publication Critical patent/BRPI0722361B1/pt
Publication of BRPI0722361B8 publication Critical patent/BRPI0722361B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493—Immunosupressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

reagente de extração de fármaco imunossupressor para imunoensaios uma composição melhorada de reagente extrativo e método para extrair um fármaco imussupressor, tal como sirolimus, tacrolimus ou ciclosporina, de amostras de sangue ao mesmo tempo em que produz um extrato de amostra de teste que tenha baixa pressão de vapor e que seja compatível com componentes de imunoensaio. a composição inventiva de reagente compreende sulfóxido de dimetila (dmso), pelo menos um sal de metal divalente e água. os extratos das amostras resultantes do uso de cada uma destas combinações têm baixa pressão de vapor e são compatíveis com os ensaios imunoquímicos.
BRPI0722361A 2007-12-19 2007-12-19 métodos para avaliar a concentração de um fármaco imunossupressor em uma amostra de sangue humano, composição de reagente de extração e kit de teste BRPI0722361B8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/088056 WO2009078875A1 (en) 2007-12-19 2007-12-19 Immunosuppressant drug extraction reagent for immunoassays

Publications (4)

Publication Number Publication Date
BRPI0722361A2 BRPI0722361A2 (pt) 2014-04-29
BRPI0722361A8 BRPI0722361A8 (pt) 2018-05-22
BRPI0722361B1 BRPI0722361B1 (pt) 2018-10-23
BRPI0722361B8 true BRPI0722361B8 (pt) 2021-07-27

Family

ID=40795810

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0722361A BRPI0722361B8 (pt) 2007-12-19 2007-12-19 métodos para avaliar a concentração de um fármaco imunossupressor em uma amostra de sangue humano, composição de reagente de extração e kit de teste

Country Status (7)

Country Link
EP (1) EP2232264B1 (pt)
JP (1) JP5134692B2 (pt)
CN (1) CN101946179B (pt)
BR (1) BRPI0722361B8 (pt)
CA (1) CA2709272C (pt)
ES (1) ES2559311T3 (pt)
WO (1) WO2009078875A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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US7883855B2 (en) 2006-07-21 2011-02-08 Abbott Laboratories Immunosuppressant drug extraction reagent for immunoassays
CA2815085C (en) 2010-10-22 2022-06-21 T2 Biosystems, Inc. Nmr systems and methods for the rapid detection of analytes
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EP2839038B1 (en) 2012-04-20 2019-01-16 T2 Biosystems, Inc. Compositions and methods for detection of candida species
US9157910B2 (en) 2013-03-15 2015-10-13 Abbott Laboratories Assay with increased dynamic range
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WO2017127731A1 (en) 2016-01-21 2017-07-27 T2 Biosystems, Inc. Nmr methods and systems for the rapid detection of bacteria
WO2019131380A1 (ja) * 2017-12-25 2019-07-04 富士レビオ株式会社 マクロライド系免疫抑制剤についての血液検査方法
CN114509526A (zh) * 2021-12-31 2022-05-17 福建医科大学孟超肝胆医院(福州市传染病医院) 一种基于lc-ms/ms的纯溶剂型全血免疫抑制剂药物浓度联检试剂盒及检测方法

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JP4968611B2 (ja) * 2006-12-29 2012-07-04 アボット・ラボラトリーズ 免疫抑制剤の改善された測定法

Also Published As

Publication number Publication date
CA2709272A1 (en) 2009-06-25
CN101946179A (zh) 2011-01-12
BRPI0722361A8 (pt) 2018-05-22
ES2559311T3 (es) 2016-02-11
JP2011508209A (ja) 2011-03-10
EP2232264B1 (en) 2015-12-02
WO2009078875A1 (en) 2009-06-25
CA2709272C (en) 2015-03-10
EP2232264A4 (en) 2011-04-20
EP2232264A1 (en) 2010-09-29
BRPI0722361B1 (pt) 2018-10-23
BRPI0722361A2 (pt) 2014-04-29
CN101946179B (zh) 2014-08-13
JP5134692B2 (ja) 2013-01-30

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 23/10/2018, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/12/2007, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO