BRPI0721056B8 - moléculas indicadoras resistentes a oxidação - Google Patents

moléculas indicadoras resistentes a oxidação Download PDF

Info

Publication number
BRPI0721056B8
BRPI0721056B8 BRPI0721056A BRPI0721056A BRPI0721056B8 BR PI0721056 B8 BRPI0721056 B8 BR PI0721056B8 BR PI0721056 A BRPI0721056 A BR PI0721056A BR PI0721056 A BRPI0721056 A BR PI0721056A BR PI0721056 B8 BRPI0721056 B8 BR PI0721056B8
Authority
BR
Brazil
Prior art keywords
indicator molecules
oxidation resistant
resistant indicator
compounds
acid residue
Prior art date
Application number
BRPI0721056A
Other languages
English (en)
Inventor
E Colvin Arthur
Modzelewska Aneta
Alan Mortellaro Mark
Original Assignee
Sensors For Medicine And Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sensors For Medicine And Science Inc filed Critical Sensors For Medicine And Science Inc
Publication of BRPI0721056A2 publication Critical patent/BRPI0721056A2/pt
Publication of BRPI0721056B1 publication Critical patent/BRPI0721056B1/pt
Publication of BRPI0721056B8 publication Critical patent/BRPI0721056B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"moléculas indicadoras resistentes a o- xidação". compostos tendo aperfeiçoada estabilidade de óxidação são mostrados. os compostos têm um resíduo de ácido aril borônico tendo um ou mais grupos de retirada de elétrons sobre a metade aromática que contém o resíduo de ácido borônico, de modo que a molécula tem aperfeiçoada resistência de óxidação comparada a uma molécula correspem quente sem o um ou mais grupos de retirada de elétrons .
BRPI0721056A 2006-11-30 2007-11-30 moléculas indicadoras resistentes a oxidação BRPI0721056B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86170706P 2006-11-30 2006-11-30
US60/861,707 2006-11-30
US90329107P 2007-02-26 2007-02-26
US60/903,291 2007-02-26
PCT/US2007/024704 WO2008066921A2 (en) 2006-11-30 2007-11-30 Oxidation resistant indicator molecules

Publications (3)

Publication Number Publication Date
BRPI0721056A2 BRPI0721056A2 (pt) 2017-05-16
BRPI0721056B1 BRPI0721056B1 (pt) 2017-10-24
BRPI0721056B8 true BRPI0721056B8 (pt) 2019-11-19

Family

ID=39284160

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0721056A BRPI0721056B8 (pt) 2006-11-30 2007-11-30 moléculas indicadoras resistentes a oxidação

Country Status (14)

Country Link
US (2) US7851225B2 (pt)
EP (1) EP2099807B1 (pt)
JP (2) JP5517624B2 (pt)
KR (1) KR101492849B1 (pt)
CN (1) CN101541813B (pt)
AU (1) AU2007325650B2 (pt)
BR (1) BRPI0721056B8 (pt)
CA (1) CA2670457C (pt)
DK (1) DK2099807T3 (pt)
HK (1) HK1130262A1 (pt)
MX (1) MX2009005781A (pt)
SG (1) SG179448A1 (pt)
TW (1) TWI431100B (pt)
WO (1) WO2008066921A2 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8029765B2 (en) * 2003-12-24 2011-10-04 Masimo Laboratories, Inc. SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
EP2536335A1 (en) * 2010-02-19 2012-12-26 Glysure Ltd Intravascular glucose sensor
US20130315829A1 (en) * 2010-04-23 2013-11-28 The Regents Of The University Of California Compounds and Methods for Detecting Reactive Oxygen Species
US8822722B2 (en) * 2010-09-30 2014-09-02 Terumo Kabushiki Kaisha Fluorescent hydrogel and method for producing the same, and sensor for measuring saccharides using the same
AU2012229109A1 (en) 2011-03-15 2013-10-10 Senseonics, Incorporated Integrated catalytic protection of oxidation sensitive materials
US9051598B2 (en) * 2011-05-02 2015-06-09 The Hong Kong University Of Science And Technology Specific detection of D-glucose by a tetraphenylethene-base fluorescent sensor
WO2013101665A1 (en) * 2011-12-30 2013-07-04 Dow Agrosciences Llc Methods of forming 4-chloro-2-fluoro-3-substituted-phenylboronic acid pinacol esters and methods of using the same
JP2015509803A (ja) 2012-03-15 2015-04-02 ライトシップ メディカル リミテッド センサー
US9963556B2 (en) 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
CN103694269B (zh) * 2013-11-27 2016-04-27 中国科学院上海微系统与信息技术研究所 一种可检测仲胺的化合物及其制备和应用
US9814413B2 (en) 2014-07-24 2017-11-14 Thomas Jefferson University Long-term implantable monitoring system and methods of use
EP3484367B1 (en) 2016-07-18 2022-01-05 Siemens Healthcare Diagnostics Inc. Biofouling prevention of wearable sensors and calibration related thereto
JP6758393B2 (ja) * 2016-09-30 2020-09-23 富士フイルム株式会社 高分子化合物
CN110352036B (zh) 2016-12-21 2022-11-15 普罗菲尤萨股份有限公司 可聚合的近红外染料
JOP20190161A1 (ar) 2016-12-27 2017-06-16 Profusa Inc مستشعرات جلوكوز بطيف قريب من الأشعة تحت الحمراء
WO2018184012A1 (en) 2017-03-31 2018-10-04 Capillary Biomedical, Inc. Helical insertion infusion device
CN115868982A (zh) 2017-04-19 2023-03-31 传感技术股份有限公司 对分析物指示剂变化的检测和修正
KR20220115927A (ko) 2019-10-25 2022-08-19 세르카코르 래버러토리즈, 인크. 지표 화합물, 지표 화합물을 포함하는 장치, 및 이의 제조 및 사용 방법
US11881093B2 (en) 2020-08-20 2024-01-23 Denso International America, Inc. Systems and methods for identifying smoking in vehicles
US11828210B2 (en) 2020-08-20 2023-11-28 Denso International America, Inc. Diagnostic systems and methods of vehicles using olfaction
US11760169B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Particulate control systems and methods for olfaction sensors
US11636870B2 (en) 2020-08-20 2023-04-25 Denso International America, Inc. Smoking cessation systems and methods
US11760170B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Olfaction sensor preservation systems and methods
US12017506B2 (en) 2020-08-20 2024-06-25 Denso International America, Inc. Passenger cabin air control systems and methods
US11932080B2 (en) 2020-08-20 2024-03-19 Denso International America, Inc. Diagnostic and recirculation control systems and methods
US11813926B2 (en) 2020-08-20 2023-11-14 Denso International America, Inc. Binding agent and olfaction sensor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9024775D0 (en) * 1990-11-14 1991-01-02 Axis Research Chemical compounds
GB2284809B (en) 1993-11-07 1998-04-29 Japan Res Dev Corp A fluorescent phenylboronic acid suitable for use in the detection of saccharides
US6002954A (en) * 1995-11-22 1999-12-14 The Regents Of The University Of California Detection of biological molecules using boronate-based chemical amplification and optical sensors
CA2235738C (en) * 1995-11-22 2005-07-26 Minimed, Inc. Detection of biological molecules using chemical amplification and optical sensors
DK2292626T3 (da) * 2000-08-04 2014-06-10 Senseonics Inc Påvisning af analytter i vandige miljøer
US20020127626A1 (en) 2001-01-05 2002-09-12 Sensors For Medicine And Science, Inc. Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
US6800451B2 (en) * 2001-01-05 2004-10-05 Sensors For Medicine And Science, Inc. Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
WO2004096817A1 (en) 2003-03-28 2004-11-11 Terumo Corporation Of Japan Solid-phase saccharide sensing compounds

Also Published As

Publication number Publication date
BRPI0721056B1 (pt) 2017-10-24
TWI431100B (zh) 2014-03-21
EP2099807A2 (en) 2009-09-16
CA2670457C (en) 2016-08-09
JP5517624B2 (ja) 2014-06-11
US20080145944A1 (en) 2008-06-19
BRPI0721056A2 (pt) 2017-05-16
CN101541813B (zh) 2013-07-31
DK2099807T3 (da) 2014-01-27
WO2008066921A3 (en) 2008-07-17
SG179448A1 (en) 2012-04-27
TW200838985A (en) 2008-10-01
AU2007325650B2 (en) 2012-07-12
AU2007325650A1 (en) 2008-06-05
US20110081727A1 (en) 2011-04-07
JP2013083658A (ja) 2013-05-09
WO2008066921A2 (en) 2008-06-05
JP2010511863A (ja) 2010-04-15
KR20090097900A (ko) 2009-09-16
US8143068B2 (en) 2012-03-27
CA2670457A1 (en) 2008-06-05
CN101541813A (zh) 2009-09-23
KR101492849B1 (ko) 2015-02-12
MX2009005781A (es) 2009-06-10
US7851225B2 (en) 2010-12-14
EP2099807B1 (en) 2014-01-01
HK1130262A1 (en) 2009-12-24

Similar Documents

Publication Publication Date Title
BRPI0721056B8 (pt) moléculas indicadoras resistentes a oxidação
EA200970232A1 (ru) Двухосно ориентированная электроизолирующая пленка
BRPI0621446C1 (pt) composição farmacêutica para uso externo
UY31145A1 (es) Derivado de 17b+ciano-18a-homo-19-nor-androst-4-eno, su uso y medicamento que lo contiene
EP2508524A3 (en) Indole compound
AR025739A1 (es) Nuevos derivados de bencimidazolonas que tienen afinidad para receptores mezclados de serotonina y dopamina
BR0005488A (pt) Processo para a preparação de carbonato de vinileno, e o uso do mesmo
BRPI0414439A (pt) transmissor de calor
WO2009016942A1 (ja) 熱処理油組成物
BRPI0713031B8 (pt) composto de di-hidro-piran-2-ona, composição farmacêutica, e uso dos mesmos
BRPI0618445A2 (pt) uso de ésteres de ácido piroglutámico como inibidores de hidrato de gás com aperfeiçoada biodegradabilidade
BRPI1011130A8 (pt) Composto organometálico, processo de preparação de um composto organometálico,e, utilização de um composto organometálico.
PA8579901A1 (es) Bifenilcarboxamidas sustituidas con n-aril piperidina
BR112019002512A2 (pt) célula solar
AR053138A1 (es) Condensados que contienen grupos acidos
BRPI0704441A (pt) rodinha de empilhar de desvio
BR112017015740B8 (pt) Composições de fragrâncias e dispositivos para cuidados do ar
BRPI0415285A (pt) derivados de aminoalcanol
BR0317995A (pt) Combinação polimérica
BRPI0608136A2 (pt) base livre de lercanidipina
WO2008142375A3 (en) Method of carbon nanotube selection
DK1289513T3 (da) Anvendelse af aloe-emodin i behandlingen af neuroektodermale tumorer
UY31581A1 (es) Derivado 15, 16-metilen-17-(1' - propenil)-17-3' -oxidoestra-4-en-3-ona, su uso y medicamento que lo contiene
BRPI0419084A (pt) dispositivo de trancamento
ATE537816T1 (de) Leflunomid enthaltende pharmazeutische zusammensetzungen

Legal Events

Date Code Title Description
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/11/2007, OBSERVADAS AS CONDICOES LEGAIS. (CO) REF. RPI 2442 DE 24/10/2017 QUANTO AO NOME DO INVENTOR

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2646 DE 21-09-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.