BRPI0714455A8 - métodos para reparar tecido e para inativar mitoticamente e/ou letalmente células-tronco, e, célula-tronco mitoticamente inativada - Google Patents

métodos para reparar tecido e para inativar mitoticamente e/ou letalmente células-tronco, e, célula-tronco mitoticamente inativada

Info

Publication number
BRPI0714455A8
BRPI0714455A8 BRPI0714455A BRPI0714455A BRPI0714455A8 BR PI0714455 A8 BRPI0714455 A8 BR PI0714455A8 BR PI0714455 A BRPI0714455 A BR PI0714455A BR PI0714455 A BRPI0714455 A BR PI0714455A BR PI0714455 A8 BRPI0714455 A8 BR PI0714455A8
Authority
BR
Brazil
Prior art keywords
mitotically
group
lethally
inactivating
methods
Prior art date
Application number
BRPI0714455A
Other languages
English (en)
Inventor
Burt Richard
Original Assignee
Richard Burton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richard Burton filed Critical Richard Burton
Publication of BRPI0714455A2 publication Critical patent/BRPI0714455A2/pt
Publication of BRPI0714455A8 publication Critical patent/BRPI0714455A8/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

processo para epimerizar ciclohexenil cetonas e sua aplicação no processo de condensação aldol. a presente invenção refere-se a processos para produção de materiais intermediários usados em perfumarias, especificamente ciclohexenil cetonas epimerizadas. a invenção também refere-se a processos para empregar a reação epimerizante em uma reação de condensação aldol. o processo para epimerizar uma ciclohexenil cetona compreende a etapa de reagir uma cicloxenil cetona epimerizável com um hidreto metálico, preferivelmente um hidreto dos metais do grupo 1 ou grupo 2, sendo que mais preferivelmente, em que o hidreto metálico é selecionado do grupo que consiste em lih. nah, cah2 e misturas dos mesmos.grupo 2, sendo que mais preferivelmente, em que o hidreto metálico é selecionado do grupo que consiste em lih. nah, cah2 e misturas dos mesmos.
BRPI0714455A 2006-07-20 2007-07-19 métodos para reparar tecido e para inativar mitoticamente e/ou letalmente células-tronco, e, célula-tronco mitoticamente inativada BRPI0714455A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80786106P 2006-07-20 2006-07-20
US60/807861 2006-07-20
PCT/US2007/073904 WO2008011524A2 (en) 2006-07-20 2007-07-19 Method of using mitotically inactivated stem cells for damaged tissue repair

Publications (2)

Publication Number Publication Date
BRPI0714455A2 BRPI0714455A2 (pt) 2013-04-02
BRPI0714455A8 true BRPI0714455A8 (pt) 2018-10-16

Family

ID=38957623

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0714455A BRPI0714455A8 (pt) 2006-07-20 2007-07-19 métodos para reparar tecido e para inativar mitoticamente e/ou letalmente células-tronco, e, célula-tronco mitoticamente inativada

Country Status (11)

Country Link
US (3) US9017658B2 (pt)
EP (1) EP2049655A4 (pt)
JP (1) JP2009544362A (pt)
CN (1) CN101490244A (pt)
AU (1) AU2009200637A1 (pt)
BR (1) BRPI0714455A8 (pt)
CA (1) CA2659021A1 (pt)
CO (1) CO6160246A2 (pt)
MX (1) MX2009000741A (pt)
RU (1) RU2009105890A (pt)
WO (1) WO2008011524A2 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2009105890A (ru) 2006-07-20 2010-08-27 Ричард БЕРТ (US) Способ применения митотически инактивированных стволовых клеток для репарации поврежденной ткани
WO2013003595A1 (en) 2011-06-29 2013-01-03 Biorestorative Therapies, Inc. Brown fat cell compositions and methods
WO2013142192A1 (en) * 2012-03-19 2013-09-26 Richard Burt Methods and compositions for regenerating and repairing damaged tissue using nonviable irradiated or lyophilized pluripotent stem cells
US10167449B2 (en) 2013-04-19 2019-01-01 Biorestorative Therapies, Inc. Human brown adipose derived stem cells and uses
US10813955B2 (en) 2015-09-29 2020-10-27 Genani Corporation Methods for treating age-related organ or tissue dysfunction through heterochronic transbiosis using nonviable pluripotent stem cells
WO2019040790A1 (en) * 2017-08-23 2019-02-28 Merakris Therapeutics, Llc COMPOSITIONS CONTAINING AMNIOTIC COMPONENTS AND METHODS FOR THEIR PREPARATION AND USE
DE102018202268A1 (de) * 2018-02-14 2019-08-14 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Verfahren zur Erhöhung der Sicherheit von Gewebepräparaten (tissue engineered products) für die klinische Anwendung
WO2023046709A1 (en) 2021-09-23 2023-03-30 Aarhus Universitet Ready-to-use stem cell therapeutic

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5837539A (en) 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
AU4543193A (en) 1992-06-22 1994-01-24 Henry E. Young Scar inhibitory factor and use thereof
WO1999027076A1 (en) * 1997-11-25 1999-06-03 Arc Genomic Research Pluripotent embryonic stem cells and methods of obtaining them
US20030161817A1 (en) 2001-03-28 2003-08-28 Young Henry E. Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
AU2003206844B2 (en) 2002-02-06 2010-04-08 Tissuedent Gmbh & Co. Kg Pluripotent embryonic-like stem cells derived from teeth and uses thereof
DK1539929T3 (da) * 2002-06-28 2013-07-15 Life Technologies Corp Fremgangsmåder til genoprettelse af immunrepertoiret i patienter med immunologiske defekter i forbindelse med autoimmunitet og transplantation af organer eller hæmatopoeitiske stamceller
JP2005532810A (ja) 2002-07-16 2005-11-04 イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム 組織修復および組織形成のために間葉性幹細胞を移植する方法
NZ597965A (en) 2003-10-08 2013-09-27 Vet Stem Inc Methods of preparing and using stem cell compositions and kits comprising the same
US20070092494A1 (en) 2005-10-26 2007-04-26 Biomet Manufacturing Corp. Composition for wound healing using lyophilized skin or skin-derived collagen
US8871198B2 (en) 2006-03-29 2014-10-28 Stemnion, Inc. Methods related to wound healing
US20070292401A1 (en) 2006-06-20 2007-12-20 Harmon Alexander M Soft tissue repair and regeneration using stem cell products
RU2009105890A (ru) 2006-07-20 2010-08-27 Ричард БЕРТ (US) Способ применения митотически инактивированных стволовых клеток для репарации поврежденной ткани
US20080241113A1 (en) 2007-03-01 2008-10-02 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of endometrial/menstrual cells
WO2009065093A2 (en) 2007-11-17 2009-05-22 University Of Medicine And Dentistry Of New Jersey Use of stem cells for wound healing
CN101449822A (zh) 2007-12-05 2009-06-10 詹承镇 胚胎端粒酶食品
US20100040583A1 (en) 2008-03-27 2010-02-18 Vincent Falanga Compositions and methods using stem cells in cutaneous wound healing

Also Published As

Publication number Publication date
MX2009000741A (es) 2009-07-17
JP2009544362A (ja) 2009-12-17
EP2049655A2 (en) 2009-04-22
US9017658B2 (en) 2015-04-28
US9867855B2 (en) 2018-01-16
US20090214491A1 (en) 2009-08-27
CO6160246A2 (es) 2010-05-20
AU2009200637A1 (en) 2009-03-12
EP2049655A4 (en) 2010-04-21
WO2008011524A2 (en) 2008-01-24
WO2008011524A3 (en) 2008-12-24
CN101490244A (zh) 2009-07-22
US20160022744A1 (en) 2016-01-28
CA2659021A1 (en) 2008-01-24
RU2009105890A (ru) 2010-08-27
US20150328265A1 (en) 2015-11-19
BRPI0714455A2 (pt) 2013-04-02

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL