BRPI0714221A2 - composições e métodos para o tratamento de mucormicose e outras doenças fúngicas - Google Patents

composições e métodos para o tratamento de mucormicose e outras doenças fúngicas Download PDF

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Publication number
BRPI0714221A2
BRPI0714221A2 BRPI0714221-8A BRPI0714221A BRPI0714221A2 BR PI0714221 A2 BRPI0714221 A2 BR PI0714221A2 BR PI0714221 A BRPI0714221 A BR PI0714221A BR PI0714221 A2 BRPI0714221 A2 BR PI0714221A2
Authority
BR
Brazil
Prior art keywords
iron
mucormycosis
antifungal agent
iron chelating
antifungal
Prior art date
Application number
BRPI0714221-8A
Other languages
English (en)
Portuguese (pt)
Inventor
Brad J Spellberg
John E Edwards
Ashraf S Ibrahim
Original Assignee
Los Angeles Biomed Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Los Angeles Biomed Res Inst filed Critical Los Angeles Biomed Res Inst
Publication of BRPI0714221A2 publication Critical patent/BRPI0714221A2/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0714221-8A 2006-07-13 2007-07-13 composições e métodos para o tratamento de mucormicose e outras doenças fúngicas BRPI0714221A2 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US83109906P 2006-07-13 2006-07-13
US60/831,099 2006-07-13
US89762007P 2007-01-26 2007-01-26
US60/897,620 2007-01-26
US90407507P 2007-02-27 2007-02-27
US60/904,075 2007-02-27
PCT/US2007/016065 WO2008008537A2 (en) 2006-07-13 2007-07-13 Combi) compositions for the treatment of mucormycosis. comprising iron chelator and antifungal agent

Publications (1)

Publication Number Publication Date
BRPI0714221A2 true BRPI0714221A2 (pt) 2013-01-01

Family

ID=38610625

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0714221-8A BRPI0714221A2 (pt) 2006-07-13 2007-07-13 composições e métodos para o tratamento de mucormicose e outras doenças fúngicas

Country Status (18)

Country Link
US (1) US20100129434A1 (https=)
EP (2) EP2412371A1 (https=)
JP (2) JP2009543788A (https=)
KR (1) KR20090036587A (https=)
AU (1) AU2007272781B2 (https=)
BR (1) BRPI0714221A2 (https=)
CA (1) CA2657634A1 (https=)
CL (1) CL2007002026A1 (https=)
IL (1) IL196389A0 (https=)
MA (1) MA30625B1 (https=)
MX (1) MX2009000506A (https=)
NO (1) NO20090565L (https=)
NZ (1) NZ574862A (https=)
RU (1) RU2464024C2 (https=)
SG (1) SG177122A1 (https=)
TN (1) TN2009000004A1 (https=)
TW (1) TWI448285B (https=)
WO (1) WO2008008537A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ614255A (en) * 2009-03-19 2015-03-27 Los Angeles Biomed Res Inst Vaccine compositions and methods for treatment of mucormycosis and other fungal diseases
US8980876B2 (en) 2010-10-28 2015-03-17 The Procter & Gamble Company Inhibition of microbial growth by aconitase inhibition
MX2015003729A (es) * 2012-11-12 2015-06-15 Cipla Ltd Composiciones farmaceuticas de dosis fija que comprende deferasirox y deferiprona.
US11229685B2 (en) 2013-01-29 2022-01-25 Case Western Reserve University Fungal iron acquisition inhibitors and uses thereof
WO2015026852A1 (en) * 2013-08-19 2015-02-26 Rutgers, The State University Of New Jersey Method of inducing an anti-retroviral immune response by counter-acting retro-virus induced anti-apoptosis
US20170239182A1 (en) * 2014-08-13 2017-08-24 Mark E. Hayes Pharmaceutical formulations of and methods to prepare chelating agents for efficient metal removal treatment systems
WO2016025611A2 (en) * 2014-08-13 2016-02-18 Zoneone Pharma, Inc. Pharmaceutical formulations of chelating agents as a metal removal treatment system
EP3344246A4 (en) * 2015-08-31 2019-04-10 The University of Adelaide METHOD AND PRODUCTS FOR THE PREVENTION AND / OR TREATMENT OF MICROORGANISM INFECTIONS WITH IRON-CHELATORS AND IRON-FREE PORPHYRINE
US10960002B2 (en) 2016-05-13 2021-03-30 The Brigham And Women's Hospital, Inc. Volatile metabolite profiles for the diagnosis and treatment of Mucorales fungi
FR3095755A1 (fr) * 2019-05-10 2020-11-13 Balmes Transplantation Nouveaux médicaments cytoprotecteurs
CN113905715B (zh) 2019-06-28 2025-04-15 宝洁公司 光增强处理方法
JP2023057423A (ja) * 2021-10-11 2023-04-21 国立大学法人 熊本大学 ムコール症治療薬

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8329043D0 (en) * 1983-10-31 1983-11-30 Hider R C Pharmaceutical compositions
US4698431A (en) * 1985-11-12 1987-10-06 The United States Of America As Represented By The United States Department Of Energy Hydroxypyridonate chelating agents
PH31594A (en) * 1993-09-30 1998-11-03 Janssen Pharmaceutica Nv Oral formulations on an antifungal.
MY129541A (en) 1996-06-25 2007-04-30 Novartis Ag Substituded 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators
WO1999009997A1 (en) * 1997-08-26 1999-03-04 Board Of Regents, The University Of Texas System Edta and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections
EP1223308B1 (de) * 2000-12-16 2007-01-24 ALSTOM Technology Ltd Komponente einer Strömungsmaschine
GB0223978D0 (en) 2002-10-15 2002-11-20 Novartis Ag Organic compound
ITMI20022447A1 (it) * 2002-11-19 2004-05-20 Carlo Ghisalberti Uso di piridinoni nel trattamento della purpura capillare ed affezioni cutanee correlate.
JP2006513235A (ja) * 2002-12-31 2006-04-20 ネクター セラピューティクス 真菌感染症療法のためのエアゾール化可能な医薬製剤
WO2004108114A2 (en) * 2003-03-31 2004-12-16 Dinesh Shantilal Patel Anti-fungal composition and a process for its manufacture
DE10356409B4 (de) * 2003-11-28 2006-12-28 Biofrontera Discovery Gmbh Neues Arzneimittel Oxachelin und Derivate

Also Published As

Publication number Publication date
US20100129434A1 (en) 2010-05-27
NZ574862A (en) 2012-02-24
MX2009000506A (es) 2009-05-20
JP2009543788A (ja) 2009-12-10
TW200816994A (en) 2008-04-16
AU2007272781A1 (en) 2008-01-17
WO2008008537A3 (en) 2008-04-24
JP2013040212A (ja) 2013-02-28
RU2464024C2 (ru) 2012-10-20
EP2412371A1 (en) 2012-02-01
IL196389A0 (en) 2009-09-22
TN2009000004A1 (en) 2010-08-19
TWI448285B (zh) 2014-08-11
EP2043636A2 (en) 2009-04-08
MA30625B1 (fr) 2009-08-03
CL2007002026A1 (es) 2008-06-06
AU2007272781B2 (en) 2012-10-18
WO2008008537A2 (en) 2008-01-17
RU2009104961A (ru) 2010-08-20
KR20090036587A (ko) 2009-04-14
NO20090565L (no) 2009-03-30
CA2657634A1 (en) 2008-01-17
SG177122A1 (en) 2012-01-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2314 DE 12-05-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.