BRPI0607168A2 - terapia de combinação parenteral, composição farmacêutica, processo para preparar uma composição farmacêutica e método de tratamento - Google Patents

terapia de combinação parenteral, composição farmacêutica, processo para preparar uma composição farmacêutica e método de tratamento

Info

Publication number
BRPI0607168A2
BRPI0607168A2 BRPI0607168-6A BRPI0607168A BRPI0607168A2 BR PI0607168 A2 BRPI0607168 A2 BR PI0607168A2 BR PI0607168 A BRPI0607168 A BR PI0607168A BR PI0607168 A2 BRPI0607168 A2 BR PI0607168A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
present
compositions
preparing
combination therapy
Prior art date
Application number
BRPI0607168-6A
Other languages
English (en)
Inventor
Manu Chaudhary
Original Assignee
Venus Remedies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Venus Remedies Ltd filed Critical Venus Remedies Ltd
Publication of BRPI0607168A2 publication Critical patent/BRPI0607168A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

TERAPIA DE COMBINAçãO PARENTERAL, COMPOSIçãO FARMACêUTICA, PROCESSO PARA PREPARAR UMA COMPOSIçãO FARMACêUTICA E MéTODO DE TRATAMENTO. A presente invenção refere-se a uma composição farmacêutica para lutar contra bactérias resistentes a drogas múltiplas. São propostas composições que compreendem glicopeptídeos, em particular a vancomicina, e cefalosporinas, em particular a ceftriaxona. Constatou-se que essas composições são úteis para a administração parenteral em pacientes internados que sofrem de infecções sérias. Especificamente, a presente invenção também propõe uma composição farmacêutica que compreende ainda um excipiente tal como um agente CVMC e está disponível na forma de um pó seco para reconstituição com um solvente apropriado. Constatou-se que as composições farmacêuticas da presente invenção melhoram normalmente a resistência à precipitação em soluções a ser administradas por via parenteral, A presente invenção também fornece detalhes das formas de dosagem armazenadas em recipientes lacrados que vão ser reconstituidas antes do uso. A presente invenção propõe ainda um processo para a fabricação dessas composições e também um método para tratar um sujeito que sofre de afecções infecciosas não-oculares devido a bactérias resistentes a drogas múltiplas.
BRPI0607168-6A 2005-02-14 2006-02-08 terapia de combinação parenteral, composição farmacêutica, processo para preparar uma composição farmacêutica e método de tratamento BRPI0607168A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN308DE2005 2005-02-14
PCT/IN2006/000044 WO2006085337A1 (en) 2005-02-14 2006-02-08 Parenteral combination therpy for infective conditions with drug resistant bacterium

Publications (1)

Publication Number Publication Date
BRPI0607168A2 true BRPI0607168A2 (pt) 2009-08-11

Family

ID=36337659

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0607168-6A BRPI0607168A2 (pt) 2005-02-14 2006-02-08 terapia de combinação parenteral, composição farmacêutica, processo para preparar uma composição farmacêutica e método de tratamento

Country Status (15)

Country Link
US (2) US7960337B2 (pt)
EP (1) EP1848413B1 (pt)
JP (1) JP4918502B2 (pt)
KR (2) KR20090052893A (pt)
CN (1) CN101080221A (pt)
AU (1) AU2006213441B2 (pt)
BR (1) BRPI0607168A2 (pt)
CA (1) CA2597812C (pt)
ES (1) ES2482700T3 (pt)
MX (1) MX2007009754A (pt)
NZ (1) NZ555077A (pt)
PT (1) PT1848413E (pt)
UA (1) UA91208C2 (pt)
WO (1) WO2006085337A1 (pt)
ZA (1) ZA200704393B (pt)

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JP2008540515A (ja) * 2005-05-13 2008-11-20 ヴィーナス・レメディーズ・リミテッド 嚢胞性線維症を含む重症感染症の処置および管理
CN101129383B (zh) * 2006-08-25 2014-04-02 天津和美生物技术有限公司 含氨基糖苷类抗生素的抗生素复方
CN101129381B (zh) * 2006-08-25 2012-02-01 天津和美生物技术有限公司 含β-内酰胺类抗生素和离子螯合剂的抗生素复方
CN101129382B (zh) * 2006-08-25 2013-12-25 天津和美生物技术有限公司 含β-内酰胺类抗生素和缓冲组分的抗生素复方
GB2459126A (en) * 2008-04-10 2009-10-14 Peter Wilson Antimicrobial agent
WO2011011783A1 (en) * 2009-07-24 2011-01-27 University Of Tennessee Research Foundation Spectinamides as anti-tuberculosis agents
CN108785654A (zh) * 2009-11-23 2018-11-13 丘比斯特制药有限责任公司 脂肽组合物和相关方法
CA2823628A1 (en) 2011-01-05 2012-07-12 Hospira, Inc. Spray drying vancomycin
ITLO20110001A1 (it) * 2011-05-03 2012-11-04 Fisiopharma Srl Flaconi di vancomicina cloroidrata con stabilità migliorata
RU2491921C1 (ru) * 2012-07-11 2013-09-10 Общество с ограниченной ответственностью "Опытно-технологическая фирма "Этрис" Способ лечения мастита у коров в сухостойный период
WO2014152996A1 (en) 2013-03-14 2014-09-25 Cubist Pharmaceuticals, Inc. Crystalline form of a beta-lactamase inhibitor
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
CN104043104B (zh) 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法
AU2014227660B2 (en) * 2013-03-15 2014-11-06 Merck Sharp & Dohme Llc Ceftolozane antibiotic compositions
WO2014151845A1 (en) 2013-03-15 2014-09-25 Scuderi Group, Inc. Split-cycle engines with direct injection
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane
US9120796B2 (en) 2013-10-02 2015-09-01 Cubist Pharmaceuticals, Inc. B-lactamase inhibitor picoline salt
BE1021242B1 (nl) * 2014-06-11 2015-09-08 Neogen N.V. Teicoplanine lyofilisaten
CR20170234A (es) 2014-11-06 2018-01-15 Xellia Pharmaceuticals Aps Composiciones de antibiótico
US20210213096A1 (en) * 2016-02-19 2021-07-15 Forschungszentrum Borstel Leibniz-Zentrum Fur Medizin Und Biowssenschaften Means and methods for treating bacterial infections
WO2017194385A1 (en) 2016-05-09 2017-11-16 Xellia Pharmaceuticals Aps Stabilized glycopeptide antibiotic formulations
CN107661470A (zh) * 2016-08-29 2018-02-06 成都特兰辰亚生物科技有限公司 添加有萘夫西林钠治疗痢疾的组合物
US20220133844A1 (en) 2020-10-30 2022-05-05 Somerset Therapeutics, Llc Glycopeptide antibiotics liquid formulations and methods and uses thereof
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EP4014965A1 (en) 2020-12-16 2022-06-22 EVER Valinject GmbH Aqueous solution

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Also Published As

Publication number Publication date
EP1848413B1 (en) 2014-04-09
US20110257079A1 (en) 2011-10-20
US20080188403A1 (en) 2008-08-07
MX2007009754A (es) 2007-11-07
JP4918502B2 (ja) 2012-04-18
WO2006085337B1 (en) 2006-11-02
PT1848413E (pt) 2014-07-18
JP2008530082A (ja) 2008-08-07
WO2006085337A1 (en) 2006-08-17
CA2597812A1 (en) 2006-08-17
KR20090052893A (ko) 2009-05-26
CA2597812C (en) 2012-01-24
AU2006213441B2 (en) 2011-12-01
NZ555077A (en) 2010-03-26
US7960337B2 (en) 2011-06-14
US8778873B2 (en) 2014-07-15
CN101080221A (zh) 2007-11-28
AU2006213441A1 (en) 2006-08-17
EP1848413A1 (en) 2007-10-31
UA91208C2 (ru) 2010-07-12
ES2482700T3 (es) 2014-08-04
KR20070085674A (ko) 2007-08-27
ZA200704393B (en) 2008-09-25

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2364 DE 26-04-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.