BRPI0607045A2 - células estromais adultas derivadas de adiposas exibindo caracterìsticas de células endoteliais - Google Patents
células estromais adultas derivadas de adiposas exibindo caracterìsticas de células endoteliaisInfo
- Publication number
- BRPI0607045A2 BRPI0607045A2 BRPI0607045-0A BRPI0607045A BRPI0607045A2 BR PI0607045 A2 BRPI0607045 A2 BR PI0607045A2 BR PI0607045 A BRPI0607045 A BR PI0607045A BR PI0607045 A2 BRPI0607045 A2 BR PI0607045A2
- Authority
- BR
- Brazil
- Prior art keywords
- adipose
- cell
- endothelial cell
- stromal cells
- derived adult
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
CéLULAS ESTROMAIS ADULTAS DERIVADAS DE ADIPOSAS EXIBINDO CARACTERìSTICAS DE CéLULAS ENDOTELIAIS. A presente invenção engloba uma célula estromal adulta derivada de adiposa (ADAS) que exibe pelo menos uma característica de uma célula pré-endotelial e/ou célula endotelial. A presente invenção também engloba composições e métodos para a geração de uma célula estromal adulta derivada de adiposa que exiba pelo menos uma característica de uma célula pré-endotelial e/ou célula endotelial. Também estão incluidos métodos de uso das células em transplante vascular, engenharia de tecidos, regulação da angiogênese, vasculogênese e tratamento de inúmeros transtornos, incluindo doença cardíaca.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64863005P | 2005-01-31 | 2005-01-31 | |
PCT/US2006/004710 WO2006084284A2 (en) | 2005-01-31 | 2006-01-27 | Adipose derived adult stromal cells exhibiting characteristics of endothelial cells |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0607045A2 true BRPI0607045A2 (pt) | 2009-08-04 |
Family
ID=36778041
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0607045-0A BRPI0607045A2 (pt) | 2005-01-31 | 2006-01-27 | células estromais adultas derivadas de adiposas exibindo caracterìsticas de células endoteliais |
Country Status (14)
Country | Link |
---|---|
US (1) | US20060171932A1 (pt) |
EP (1) | EP1859025A4 (pt) |
JP (1) | JP2008528041A (pt) |
KR (1) | KR20070100908A (pt) |
CN (1) | CN101155912A (pt) |
AU (1) | AU2006210425A1 (pt) |
BR (1) | BRPI0607045A2 (pt) |
CA (1) | CA2596281A1 (pt) |
CR (1) | CR9346A (pt) |
IL (1) | IL184890A0 (pt) |
MX (1) | MX2007009173A (pt) |
RU (1) | RU2007132733A (pt) |
TW (1) | TW200637911A (pt) |
WO (1) | WO2006084284A2 (pt) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2344653A1 (en) | 1998-09-29 | 2000-04-06 | Gamida Cell Ltd. | Methods of controlling proliferation and differentiation of stem and progenitor cells |
IL152904A0 (en) * | 2002-01-24 | 2003-06-24 | Gamida Cell Ltd | Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations |
WO2003062404A1 (en) | 2002-01-25 | 2003-07-31 | Gamida-Cell Ltd. | Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby |
CA2479679A1 (en) * | 2002-03-18 | 2003-09-25 | Gamida-Cell Ltd. | Methods of inducing differentiation in ex vivo expanded stem cells |
US20050054097A1 (en) * | 2002-11-17 | 2005-03-10 | Tony Peled | EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures |
WO2006030442A2 (en) | 2004-09-16 | 2006-03-23 | Gamida-Cell Ltd. | Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells |
US8846393B2 (en) | 2005-11-29 | 2014-09-30 | Gamida-Cell Ltd. | Methods of improving stem cell homing and engraftment |
US20080199441A1 (en) * | 2006-11-09 | 2008-08-21 | Tony Peled | Use of ex-vivo cultured hematopoietic cells for treatment of peripheral vascular diseases |
US20080299077A1 (en) * | 2007-06-01 | 2008-12-04 | Nevada Cancer Institute | Isolation and growth of stem cells from hemangiomas |
WO2008151021A1 (en) * | 2007-06-01 | 2008-12-11 | Nevada Cancer Institute | Isolation and growth of stem cells from hemangiomas |
US9096827B2 (en) * | 2008-09-02 | 2015-08-04 | Pluristem Ltd. | Adherent cells from placenta tissue and use thereof in therapy |
JP2012505665A (ja) * | 2008-10-17 | 2012-03-08 | バクスター・インターナショナル・インコーポレイテッド | 脂肪組織から細胞集団を得る方法 |
US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
CN104662532B (zh) * | 2011-03-28 | 2018-09-07 | 约翰·S·阿诺尼 | 基于干细胞的化妆配制品及制备其的方法和系统 |
US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
SG11201404608WA (en) | 2012-02-13 | 2014-09-26 | Gamida Cell Ltd | Mesenchymal stem cells conditioned medium and methods of generating and using the same |
US9175266B2 (en) | 2012-07-23 | 2015-11-03 | Gamida Cell Ltd. | Enhancement of natural killer (NK) cell proliferation and activity |
US9567569B2 (en) | 2012-07-23 | 2017-02-14 | Gamida Cell Ltd. | Methods of culturing and expanding mesenchymal stem cells |
US20150037436A1 (en) | 2013-07-30 | 2015-02-05 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
KR101719743B1 (ko) | 2015-04-06 | 2017-03-24 | 박준한 | 지방 조직으로부터 지방줄기세포를 수득하는 방법 |
US10531957B2 (en) | 2015-05-21 | 2020-01-14 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
CN106520691A (zh) * | 2016-12-30 | 2017-03-22 | 潍坊医学院 | 一种皮肤间充质干细胞的分离及培养方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4352883A (en) * | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
US4353888A (en) * | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
US4678470A (en) * | 1985-05-29 | 1987-07-07 | American Hospital Supply Corporation | Bone-grafting material |
US5158881A (en) * | 1987-11-17 | 1992-10-27 | Brown University Research Foundation | Method and system for encapsulating cells in a tubular extrudate in separate cell compartments |
US5283187A (en) * | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
DE3829766A1 (de) * | 1988-09-01 | 1990-03-22 | Akzo Gmbh | Verfahren zur herstellung von membranen |
US4968859A (en) * | 1988-10-21 | 1990-11-06 | Westinghouse Electric Corp. | Circuit breaker with low voltage contact structure |
US5082670A (en) * | 1988-12-15 | 1992-01-21 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system |
US5084350A (en) * | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
US5618531A (en) * | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
US5571083A (en) * | 1994-02-18 | 1996-11-05 | Lemelson; Jerome H. | Method and system for cell transplantation |
US6342479B1 (en) * | 1997-04-08 | 2002-01-29 | Societe De Counseils De Recherches Et D'applications Scientifiques, Sas | Prolonging survival of transplanted pancreatic cells |
US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
US6153432A (en) * | 1999-01-29 | 2000-11-28 | Zen-Bio, Inc | Methods for the differentiation of human preadipocytes into adipocytes |
PT1261694E (pt) * | 2000-02-26 | 2008-04-03 | Artecel Inc | Células estaminais pluripotentes produzidas a partir de células estromais derivadas de tecido adiposo e suas utilizações. |
EP1451300A4 (en) * | 2001-11-09 | 2007-01-10 | Artecel Sciences Inc | METHODS AND COMPOSITIONS IN WHICH STROMAL CELLS ARE USED TO SUPPORT EMBRYONIC AND ADULT STEM CELLS |
CA2469472C (en) * | 2001-12-21 | 2013-11-26 | Immunex Corporation | Endothelial stem cells, populations, methods of isolation and use thereof |
AU2003220424A1 (en) * | 2002-03-19 | 2003-10-08 | Advanced Research And Technology Transfer | Adipose stromal stem cells for tissue and vascular modification |
-
2006
- 2006-01-27 MX MX2007009173A patent/MX2007009173A/es unknown
- 2006-01-27 KR KR1020077019884A patent/KR20070100908A/ko not_active Application Discontinuation
- 2006-01-27 AU AU2006210425A patent/AU2006210425A1/en not_active Abandoned
- 2006-01-27 RU RU2007132733/13A patent/RU2007132733A/ru not_active Application Discontinuation
- 2006-01-27 BR BRPI0607045-0A patent/BRPI0607045A2/pt not_active Application Discontinuation
- 2006-01-27 EP EP06734732A patent/EP1859025A4/en not_active Withdrawn
- 2006-01-27 CN CNA2006800109281A patent/CN101155912A/zh active Pending
- 2006-01-27 CA CA002596281A patent/CA2596281A1/en not_active Abandoned
- 2006-01-27 WO PCT/US2006/004710 patent/WO2006084284A2/en active Application Filing
- 2006-01-27 US US11/342,096 patent/US20060171932A1/en not_active Abandoned
- 2006-01-27 JP JP2007553394A patent/JP2008528041A/ja active Pending
- 2006-02-03 TW TW095103812A patent/TW200637911A/zh unknown
-
2007
- 2007-07-26 IL IL184890A patent/IL184890A0/en unknown
- 2007-08-28 CR CR9346A patent/CR9346A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2006084284A2 (en) | 2006-08-10 |
JP2008528041A (ja) | 2008-07-31 |
IL184890A0 (en) | 2007-12-03 |
RU2007132733A (ru) | 2009-03-10 |
CN101155912A (zh) | 2008-04-02 |
CA2596281A1 (en) | 2006-08-10 |
EP1859025A4 (en) | 2009-07-22 |
AU2006210425A1 (en) | 2006-08-10 |
TW200637911A (en) | 2006-11-01 |
KR20070100908A (ko) | 2007-10-12 |
MX2007009173A (es) | 2008-03-10 |
EP1859025A2 (en) | 2007-11-28 |
US20060171932A1 (en) | 2006-08-03 |
CR9346A (es) | 2008-02-12 |
WO2006084284A3 (en) | 2006-09-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0607045A2 (pt) | células estromais adultas derivadas de adiposas exibindo caracterìsticas de células endoteliais | |
EA201101519A1 (ru) | Способы диагностики метаболических нарушений, использующие эпиметаболические переключатели, многоаспектные внутриклеточные молекулы или факторы влияния | |
CY1119853T1 (el) | Χρηση στρωματικων βλαστοκυτταρων λαμβανομενων απο ιστο αδιποζης στην θεραπεια συριγγιου | |
WO2005086860A3 (en) | Methods for generating insulin-producing cells | |
TW200732347A (en) | VEGF analogs and methods of use | |
ECSP10010548A (es) | Composiciones y metodos de preparacion y uso de las mismas | |
ITRM20050265A1 (it) | Protesi modulare perfezionata per osteosintesi, in particolare per l'osteosintesi dell'omero. | |
UY30732A1 (es) | Compuestos para la modulacion de la actividad del c-fms y/o el c-kit y sus usos aplicables | |
ATE435656T1 (de) | Nkg2d modulation | |
DK1807083T3 (da) | Anvendelse af pirlindol til behandling af lidelser, der er kendetegnet ved proliferation af T-lymphocyter og/eller hyperproliferation af keratinocyter, især atopisk dermatitis og psoriasis | |
NO20074943L (no) | Roflumilast for behandlingen av diabetes mellitus | |
MX2007007781A (es) | Composiciones cardiovasculares. | |
MX2019008872A (es) | Prevencion y tratamiento de da?o o enfermedad osea y cartilago. | |
BR112015001874A2 (pt) | sais e formas sólidas de (s) -3- (4 - ((4-morfolinometil) benzil) oxi) -1-oxoisoindolin-2-il) -piperidina-2,6-diona e composições que compreendem e métodos de utilização das mesmas | |
CR11272A (es) | Enzimas de aciltranferasa de lecitina-colesterol, modificadas | |
ATE489371T1 (de) | Benzamidglucokinaseaktivatoren | |
CR10495A (es) | Composicion que comprende por lo menos un alcohol alifatico superior y un extracto de griffonia simplicifolia | |
NO20070746L (no) | Anvendelse av fosfaterte alkanoler som dispergente , emulgatorer, hydrotroper, fuktmidler og kompatabilitetsstoffer i blandinger for jordbruket. | |
JO2747B1 (en) | Vehicles | |
CL2007001748A1 (es) | Compuesto derivado de 2-arilamino-4-aminopirimidinas, inhibidores de la proteina quinasa c-alfa; composiciones farmaceuticas que los contienen; y su uso para tratar o prevenir la diabetes, el cancer, enfermedades cardiovasculares y otras. | |
CY1110733T1 (el) | Κυκλικα παραγωγα ως ρυθμιστες της δραστικοτητας υποδοχεα χημειοκινων | |
BR112018000909A2 (pt) | imunoconjugados de il22 | |
GT200900045A (es) | Sales de bencimidazolilo piridilo eteres y las formulaciones del mismo | |
CR9890A (es) | Composicion fungicida | |
CO2021014748A2 (es) | Conjugado de anticuerpo anti-bcma, composiciones que lo comprenden, y métodos de fabricación y uso del mismo |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Ipc: C12N 5/071 (2010.01), C12N 5/0775 (2010.01) |