BRPI0516953A - partìculas do tipo vìrus compreendendo uma proteìna de fusão da proteìna de revestimento de ap205 e um polipeptìdeo antigênico - Google Patents
partìculas do tipo vìrus compreendendo uma proteìna de fusão da proteìna de revestimento de ap205 e um polipeptìdeo antigênicoInfo
- Publication number
- BRPI0516953A BRPI0516953A BRPI0516953-4A BRPI0516953A BRPI0516953A BR PI0516953 A BRPI0516953 A BR PI0516953A BR PI0516953 A BRPI0516953 A BR PI0516953A BR PI0516953 A BRPI0516953 A BR PI0516953A
- Authority
- BR
- Brazil
- Prior art keywords
- present
- virus
- vlp
- modified
- fusion protein
- Prior art date
Links
- 108020001507 fusion proteins Proteins 0.000 title abstract 2
- 239000002245 particle Substances 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000012743 protein tagging Effects 0.000 title abstract 2
- 101710132601 Capsid protein Proteins 0.000 title 1
- 101710094648 Coat protein Proteins 0.000 title 1
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 title 1
- 101710125418 Major capsid protein Proteins 0.000 title 1
- 101710141454 Nucleoprotein Proteins 0.000 title 1
- 101710083689 Probable capsid protein Proteins 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000001939 inductive effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000005875 antibody response Effects 0.000 abstract 1
- 230000006472 autoimmune response Effects 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 206010013663 drug dependence Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000011117 substance-related disease Diseases 0.000 abstract 1
- 241001515965 unidentified phage Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6075—Viral proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
- C12N2795/18111—Leviviridae
- C12N2795/18123—Virus like particles [VLP]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61130804P | 2004-09-21 | 2004-09-21 | |
| EP05105229 | 2005-06-14 | ||
| PCT/EP2005/054721 WO2006032674A1 (en) | 2004-09-21 | 2005-09-21 | Virus-like particles comprising a fusion protein of the coat protein of ap205 and an antigenic polypeptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0516953A true BRPI0516953A (pt) | 2008-09-30 |
Family
ID=46307785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0516953-4A BRPI0516953A (pt) | 2004-09-21 | 2005-09-21 | partìculas do tipo vìrus compreendendo uma proteìna de fusão da proteìna de revestimento de ap205 e um polipeptìdeo antigênico |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080292652A1 (https=) |
| EP (1) | EP1791870A1 (https=) |
| JP (1) | JP2008513035A (https=) |
| AU (1) | AU2005286475A1 (https=) |
| BR (1) | BRPI0516953A (https=) |
| CA (1) | CA2580208A1 (https=) |
| MX (1) | MX2007003171A (https=) |
| NZ (1) | NZ554387A (https=) |
| RU (1) | RU2409667C2 (https=) |
| WO (1) | WO2006032674A1 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7264810B2 (en) * | 2001-01-19 | 2007-09-04 | Cytos Biotechnology Ag | Molecular antigen array |
| DE60234375D1 (de) * | 2001-09-14 | 2009-12-24 | Cytos Biotechnology Ag | VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG |
| EP2338510A1 (en) * | 2002-07-19 | 2011-06-29 | Novartis Pharma AG | Vaccine compositions containing amyloid beta1-6 antigen arrays |
| CN1753687A (zh) | 2002-10-29 | 2006-03-29 | 科勒制药集团股份有限公司 | Cpg寡核苷酸在治疗丙型肝炎病毒感染中的应用 |
| AU2004224761A1 (en) | 2003-03-26 | 2004-10-07 | Cytos Biotechnology Ag | HIV-peptide-carrier-conjugates |
| US7959928B2 (en) | 2004-10-05 | 2011-06-14 | Cytos Biotechnology Ag | VLP-antigen conjugates and their uses as vaccines |
| AU2005298689A1 (en) | 2004-10-25 | 2006-05-04 | Cytos Biotechnology Ag | Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof |
| CN101193654A (zh) * | 2005-06-14 | 2008-06-04 | 赛托斯生物技术公司 | 抗原偶联物及其用途 |
| ES2310062B1 (es) | 2005-07-15 | 2009-11-13 | Bionostra, S.L. | Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones. |
| NZ566971A (en) | 2005-09-28 | 2011-06-30 | Cytos Biotechnology Ag | Vaccine containing a virus like particle linked with an interleukin-1 molecule |
| CA2636139A1 (en) * | 2005-12-14 | 2007-06-21 | Cytos Biotechnology Ag | Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity |
| AT503690A1 (de) * | 2006-06-09 | 2007-12-15 | Biomay Ag | Hypoallergene moleküle |
| US8541559B2 (en) | 2006-06-12 | 2013-09-24 | Cytos Biotechnology Ag | Process for producing aggregated oligonucleotides |
| AU2013204383B2 (en) * | 2006-06-12 | 2016-09-22 | Kuros Us Llc | Processes for packaging oligonucleotides into virus-like particles of RNA bacteriophages |
| US20090142362A1 (en) * | 2006-11-06 | 2009-06-04 | Avant Immunotherapeutics, Inc. | Peptide-based vaccine compositions to endogenous cholesteryl ester transfer protein (CETP) |
| US8586728B2 (en) | 2006-12-12 | 2013-11-19 | Cytos Biotechnology Ag | Oligonucleotides containing high concentrations of guanine monomers |
| EP2121007A1 (en) * | 2006-12-21 | 2009-11-25 | Cytos Biotechnology AG | Circular ccr5 peptide conjugates and uses thereof |
| CN101245110B (zh) * | 2007-02-16 | 2010-09-15 | 鲁南制药集团股份有限公司 | 重组中性粒细胞抑制因子和水蛭原嵌合蛋白及其药物组合物 |
| US20110262472A1 (en) * | 2008-04-22 | 2011-10-27 | Cytos Biotechnology Ag | Vaccine compositions for the treatment of dengue fever and uses thereof |
| WO2010122164A1 (en) | 2009-04-23 | 2010-10-28 | Cytos Biotechnology Ag | VIRUS-LIKE PARTICLES OF BACTERIOPHAGE φCB5 |
| NZ596058A (en) * | 2009-04-30 | 2013-08-30 | Cytos Biotechnology Ag | Influenza hemagglutinin compositions and uses thereof |
| CA2793580A1 (en) * | 2010-03-29 | 2011-10-06 | Novartis Ag | Composition comprising the amyloid beta 1-6 peptide coupled to a virus-like particle and an adjuvant |
| GB201121571D0 (en) * | 2011-12-15 | 2012-01-25 | Astrimmune Ltd | Compounds and uses thereof |
| CN104011080B (zh) | 2011-12-22 | 2017-10-20 | 弗·哈夫曼-拉罗切有限公司 | 用于真核细胞的全长抗体展示系统及其用途 |
| KR102181258B1 (ko) * | 2012-02-16 | 2020-11-20 | 브이엘피 테라퓨틱스 엘엘씨 | 바이러스 유사 입자 조성물 |
| ES2736500T3 (es) | 2014-06-18 | 2020-01-02 | Morphosys Ag | Proteínas de fusión y usos de las mismas |
| CN104255335B (zh) * | 2014-08-24 | 2016-08-31 | 苗建军 | 一种吊放蔓用钳 |
| RU2568872C1 (ru) * | 2014-10-15 | 2015-11-20 | Игорь Геннадьевич Сивов | Лекарственное средство для лечения вирусного гепатита с |
| MA40824A (fr) * | 2014-10-22 | 2017-08-29 | Saiba Gmbh | Particules de cmv de type virus modifié |
| WO2016112921A1 (en) | 2015-01-15 | 2016-07-21 | University Of Copenhagen | Virus-like particle with efficient epitope display |
| EP3368068B1 (en) | 2015-10-30 | 2020-11-18 | University of Copenhagen | Virus like particle with efficient epitope display |
| EP3389693A4 (en) | 2015-12-18 | 2019-08-21 | Agilvax, Inc. | COMPOSITIONS AND METHODS RELATED TO XCT PEPTIDES |
| BR112018071965A2 (pt) * | 2016-04-27 | 2019-03-06 | Benchmark Animal Health Ltd | tratamento da dermatite atópica canina |
| CN112500456B (zh) * | 2020-12-02 | 2022-10-28 | 深圳赫兹生命科学技术有限公司 | 一种去势ap205病毒样颗粒亚单位疫苗 |
| US20220241400A1 (en) * | 2021-02-02 | 2022-08-04 | Provaxus, Inc. | Immunomodulation platform and methods of use |
| WO2022218928A1 (en) | 2021-04-12 | 2022-10-20 | Saiba AG | Modified virus-like particles of bacteriophage ap205 |
| US20240156937A1 (en) * | 2021-04-23 | 2024-05-16 | Unm Rainforest Innovations | Baceriophage virus-like particles vaccines for chlamydia trachomatis infections |
| CN114933639B (zh) * | 2022-05-05 | 2023-12-29 | 中国农业科学院兰州兽医研究所 | 非洲猪瘟病毒p72N抗原表位蛋白及其制备方法和用途 |
| CN115819623A (zh) * | 2022-12-12 | 2023-03-21 | 长春百克生物科技股份公司 | 一种重组病毒样颗粒疫苗组合物的制备及应用 |
| CN118684781A (zh) * | 2023-03-21 | 2024-09-24 | 深圳赫兹生命科学技术有限公司 | GnRH-VLP重组去势疫苗及其制备方法 |
| EP4737572A1 (en) * | 2023-06-29 | 2026-05-06 | Shenzhen Herz Life Science Technology Co., Ltd | Preparation method for castrating ap205 virus-like particle subunit vaccine |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020193565A1 (en) * | 1998-03-27 | 2002-12-19 | Stanley Margaret Anne | Antigen preparation and use |
| WO2003031466A2 (en) * | 2001-10-05 | 2003-04-17 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
| US7264810B2 (en) * | 2001-01-19 | 2007-09-04 | Cytos Biotechnology Ag | Molecular antigen array |
| US7128911B2 (en) * | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
| CA2492823A1 (en) * | 2001-09-14 | 2003-03-27 | Cytos Biotechnology Ag | In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles |
| DE60234375D1 (de) * | 2001-09-14 | 2009-12-24 | Cytos Biotechnology Ag | VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG |
| ES2316628T3 (es) * | 2001-11-07 | 2009-04-16 | Cytos Biotechnology Ag | Disposicion ordenada de antigenos que comprende rankl para el tratamiento de enfermedades oseas. |
| AU2002363382B2 (en) * | 2001-11-07 | 2007-07-19 | Cytos Biotechnology Ag | Antigen arrays presenting IL-5, IL-3 or eotaxin for treatment of allergic eosinophilic diseases |
| BR0311995A (pt) * | 2002-06-20 | 2005-04-05 | Cytos Biotechnology Ag | Partìculas semelhantes a vìrus empacotadas para o uso como adjuvantes: método de preparação e uso |
| ES2431963T3 (es) * | 2002-07-05 | 2013-11-28 | Folia Biotech Inc. | Partícula viral adyuvante |
| US7138252B2 (en) * | 2002-07-17 | 2006-11-21 | Cytos Biotechnology Ag | Molecular antigen arrays |
-
2005
- 2005-09-21 MX MX2007003171A patent/MX2007003171A/es not_active Application Discontinuation
- 2005-09-21 US US11/663,350 patent/US20080292652A1/en not_active Abandoned
- 2005-09-21 EP EP05786887A patent/EP1791870A1/en not_active Withdrawn
- 2005-09-21 AU AU2005286475A patent/AU2005286475A1/en not_active Abandoned
- 2005-09-21 CA CA002580208A patent/CA2580208A1/en not_active Abandoned
- 2005-09-21 NZ NZ554387A patent/NZ554387A/en not_active IP Right Cessation
- 2005-09-21 BR BRPI0516953-4A patent/BRPI0516953A/pt not_active IP Right Cessation
- 2005-09-21 JP JP2007532893A patent/JP2008513035A/ja active Pending
- 2005-09-21 WO PCT/EP2005/054721 patent/WO2006032674A1/en not_active Ceased
- 2005-09-21 RU RU2007114956/10A patent/RU2409667C2/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20080292652A1 (en) | 2008-11-27 |
| NZ554387A (en) | 2009-09-25 |
| WO2006032674A1 (en) | 2006-03-30 |
| AU2005286475A1 (en) | 2006-03-30 |
| RU2409667C2 (ru) | 2011-01-20 |
| CA2580208A1 (en) | 2006-03-30 |
| MX2007003171A (es) | 2007-05-23 |
| EP1791870A1 (en) | 2007-06-06 |
| RU2007114956A (ru) | 2008-10-27 |
| JP2008513035A (ja) | 2008-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2168 DE 24/07/2012. |