BRPI0514343A - combinações de quimiocinas para mobilizar células progenitoras/tronco - Google Patents
combinações de quimiocinas para mobilizar células progenitoras/troncoInfo
- Publication number
- BRPI0514343A BRPI0514343A BRPI0514343-8A BRPI0514343A BRPI0514343A BR PI0514343 A BRPI0514343 A BR PI0514343A BR PI0514343 A BRPI0514343 A BR PI0514343A BR PI0514343 A BRPI0514343 A BR PI0514343A
- Authority
- BR
- Brazil
- Prior art keywords
- stem cells
- combinations
- chemokine
- mobilize progenitor
- progenitor
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 title abstract 4
- 102000019034 Chemokines Human genes 0.000 title abstract 2
- 108010012236 Chemokines Proteins 0.000 title abstract 2
- 102100028989 C-X-C chemokine receptor type 2 Human genes 0.000 abstract 1
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 abstract 1
- 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 abstract 1
- 108010018951 Interleukin-8B Receptors Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003028 elevating effect Effects 0.000 abstract 1
- 230000001483 mobilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60136704P | 2004-08-13 | 2004-08-13 | |
| PCT/US2005/028783 WO2006020891A2 (en) | 2004-08-13 | 2005-08-11 | Chemokine combinations to mobilize progenitor/stem cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0514343A true BRPI0514343A (pt) | 2008-06-10 |
Family
ID=35908186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0514343-8A BRPI0514343A (pt) | 2004-08-13 | 2005-08-11 | combinações de quimiocinas para mobilizar células progenitoras/tronco |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060035829A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1796716A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2008509928A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101094684A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2005272653A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0514343A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2577046A1 (cg-RX-API-DMAC7.html) |
| TW (1) | TW200608991A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006020891A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8435939B2 (en) * | 2000-09-05 | 2013-05-07 | Biokine Therapeutics Ltd. | Polypeptide anti-HIV agent containing the same |
| CA2619828A1 (en) * | 2005-08-19 | 2007-02-22 | Genzyme Corporation | Methods to enhance chemotherapy |
| MX2008010895A (es) * | 2006-02-24 | 2008-09-03 | Genzyme Corp | Metodos para aumentar el flujo sanguineo y/o promover la regeneracion de tejidos. |
| JP5257068B2 (ja) | 2006-05-16 | 2013-08-07 | 小野薬品工業株式会社 | 保護されていてもよい酸性基を含有する化合物およびその用途 |
| US20090325992A1 (en) | 2006-07-31 | 2009-12-31 | Ono Pharmaceutical Co., Ltd. | Compound having cyclic group bound thereto through spiro binding and use thereof |
| US20100003224A1 (en) * | 2006-08-02 | 2010-01-07 | Genzyme Corporation | Combination Therapy |
| WO2008075371A2 (en) * | 2006-12-21 | 2008-06-26 | Biokine Therapeutics Ltd. | T-140 peptide analogs having cxcr4 super-agonist activity for immunomodulation |
| BRPI1009663A2 (pt) * | 2009-06-14 | 2016-10-11 | Biokine Therapeutics Ltd | "método para elevação dos níveis plaquetários em um indivíduo com essa necessidade, método de inibição de hemorragia em um indivíduo que a necessite e composição farmacêutica" |
| JP2014513727A (ja) | 2011-05-16 | 2014-06-05 | ジェンザイム・コーポレーション | Cxcr4拮抗薬の使用 |
| CN103159690B (zh) * | 2011-12-14 | 2015-03-25 | 朱靖华 | 对称大环胺化合物的结晶形式 |
| US9439942B2 (en) | 2012-04-24 | 2016-09-13 | Biokine Therapeutics Ltd. | Peptides and use thereof in the treatment of large cell lung cancer |
| US11116738B2 (en) | 2012-06-07 | 2021-09-14 | Children's Hospital Los Angeles | Methods for treating neutropenia using retinoid agonists |
| US11116819B2 (en) * | 2013-02-28 | 2021-09-14 | President And Fellows Of Harvard College | Methods and compositions for mobilizing stem cells |
| WO2015126989A1 (en) | 2014-02-18 | 2015-08-27 | Children's Hospital Los Angeles | Compositions and methods for treating neutropenia |
| WO2016191811A1 (en) | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| US10682390B2 (en) | 2015-07-16 | 2020-06-16 | Biokine Therapeutics Ltd. | Compositions and methods for treating cancer |
| BR112018016924A2 (pt) | 2016-02-23 | 2019-01-02 | Biolinerx Ltd | método de seleção de regime de tratamento para indivíduo que tem leucemia mieloide aguda (lma), método de maximização de resposta ao tratamento de leucemia mieloide aguda (lma), método de tratamento de lma, antagonista de cxcr4 e agente quimioterápico no tratamento de lma |
| JP2019507596A (ja) * | 2016-02-26 | 2019-03-22 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 生着性の高い造血幹細胞 |
| WO2018085574A2 (en) * | 2016-11-02 | 2018-05-11 | Washington University | Compositions comprising an integrin inhibitor and agents which interact with a chemokine and methods of use thereof |
| TW201841916A (zh) | 2017-04-12 | 2018-12-01 | 美商麥珍塔治療學股份有限公司 | 芳香烴受體拮抗劑及其用途 |
| WO2019089833A1 (en) | 2017-10-31 | 2019-05-09 | Magenta Therapeutics Inc. | Compositions and methods for hematopoietic stem and progenitor cell transplant therapy |
| EP3704232A1 (en) | 2017-10-31 | 2020-09-09 | Magenta Therapeutics, Inc. | Compositions and methods for the expansion of hematopoietic stem and progenitor cells |
| AU2018378804B2 (en) * | 2017-12-06 | 2025-10-02 | Ensoma, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
| US10058573B1 (en) * | 2017-12-06 | 2018-08-28 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem cells |
| US11260079B2 (en) | 2017-12-06 | 2022-03-01 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
| US20200338132A1 (en) | 2018-01-03 | 2020-10-29 | Magenta Therapeutics Inc. | Compositions and methods for the expansion of hematopoietic stem and progenitor cells and treatment of inherited metabolic disorders |
| US20220401481A1 (en) | 2019-11-01 | 2022-12-22 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
| WO2021222313A1 (en) | 2020-04-27 | 2021-11-04 | Magenta Therapeutics, Inc. | Methods and compositions for transducing hematopoietic stem and progenitor cells in vivo |
| WO2022197776A1 (en) | 2021-03-16 | 2022-09-22 | Magenta Therapeutics, Inc. | Dosing regimens for hematopoietic stem cell mobilization for stem cell transplants in multiple myeloma patients |
| CN116789639A (zh) * | 2022-03-14 | 2023-09-22 | 上海医药工业研究院有限公司 | Mavorixafor的纯化方法、其盐及有关物质 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4680174A (en) * | 1984-05-24 | 1987-07-14 | Damon Biotech, Inc. | Induction of immune response by immunization with encapsulated antigen-producing cells |
| US4810643A (en) * | 1985-08-23 | 1989-03-07 | Kirin- Amgen Inc. | Production of pluripotent granulocyte colony-stimulating factor |
| US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
| US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
| US6001826A (en) * | 1989-12-21 | 1999-12-14 | Anormed, Inc. | Chemical compounds |
| US5021409A (en) * | 1989-12-21 | 1991-06-04 | Johnson Matthey Plc | Antiviral cyclic polyamines |
| GB9126677D0 (en) * | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| WO1994029341A1 (en) * | 1993-06-08 | 1994-12-22 | Smithkline Beecham Corporation | Methods of enhancing bioactivity of chemokines |
| DE4320478B4 (de) * | 1993-06-21 | 2007-11-15 | Robert Bosch Gmbh | Fahrstabilitätsregler |
| WO1995016464A1 (en) * | 1993-12-14 | 1995-06-22 | Johns Hopkins University School Of Medicine | Controlled release of pharmaceutically active substances for immunotherapy |
| GB9400411D0 (en) * | 1994-01-11 | 1994-03-09 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9511357D0 (en) * | 1995-06-06 | 1995-08-02 | Johnson Matthey Plc | Improved antiviral compounds |
| US6506770B1 (en) * | 1996-06-06 | 2003-01-14 | Anormed, Inc. | Antiviral compounds |
| US6713052B1 (en) * | 1995-10-24 | 2004-03-30 | Human Genome Sciences, Inc. | Method of mobilizing stem cells with chemokine β-8 |
| EP1016726A1 (en) * | 1998-12-30 | 2000-07-05 | Introgene B.V. | Gene therapy to promote angiogenesis |
| US6365583B1 (en) * | 1999-02-02 | 2002-04-02 | Anormed, Inc. | Methods to enhance white blood cell count |
| US6750348B1 (en) * | 1999-03-24 | 2004-06-15 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| ATE428706T1 (de) * | 1999-12-17 | 2009-05-15 | Genzyme Corp | Chemokinrezeptor-bindende heterocyclische verbindungen |
| AU2001293551B2 (en) * | 2000-09-15 | 2007-08-23 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds |
| HUP0302960A3 (en) * | 2000-09-15 | 2007-03-28 | Anormed Inc | Chemokine receptor binding heterocyclic compounds, their use and pharmaceutical compositions contining them |
| CN1457339A (zh) * | 2000-09-15 | 2003-11-19 | 阿诺麦德股份有限公司 | 趋化因子受体结合性杂环化合物 |
| BR0114246A (pt) * | 2000-09-29 | 2003-10-07 | Anormed Inc | Processo para preparação de poliaminas cìclicas contendo n nitrogênios de anel n-1 protegidas e seus produtos |
| WO2002081727A2 (en) * | 2001-04-03 | 2002-10-17 | Pe Corporation (Ny) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof |
| US7169750B2 (en) * | 2001-07-31 | 2007-01-30 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
| SI1411918T1 (sl) * | 2001-07-31 | 2012-04-30 | Genzyme Global S A R L | Postopki za mobilizacijo progenitorskih/matičnih celic |
| WO2003048345A1 (en) * | 2001-12-07 | 2003-06-12 | Toolgen, Inc. | Phenotypic screen of chimeric proteins |
| EP1613613B1 (en) * | 2003-04-11 | 2021-06-02 | Genzyme Corporation | Cxcr4 chemokine receptor binding compounds |
| US7550484B2 (en) * | 2003-04-22 | 2009-06-23 | Genzyme Corporation | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| US7491735B2 (en) * | 2003-12-11 | 2009-02-17 | Genzyme Corporation | Chemokine receptor binding compounds |
-
2005
- 2005-08-11 CN CNA2005800323327A patent/CN101094684A/zh active Pending
- 2005-08-11 JP JP2007525838A patent/JP2008509928A/ja not_active Withdrawn
- 2005-08-11 US US11/202,482 patent/US20060035829A1/en not_active Abandoned
- 2005-08-11 BR BRPI0514343-8A patent/BRPI0514343A/pt not_active IP Right Cessation
- 2005-08-11 WO PCT/US2005/028783 patent/WO2006020891A2/en not_active Ceased
- 2005-08-11 CA CA002577046A patent/CA2577046A1/en not_active Abandoned
- 2005-08-11 EP EP05788603A patent/EP1796716A4/en not_active Withdrawn
- 2005-08-11 AU AU2005272653A patent/AU2005272653A1/en not_active Abandoned
- 2005-08-12 TW TW094127548A patent/TW200608991A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005272653A1 (en) | 2006-02-23 |
| US20060035829A1 (en) | 2006-02-16 |
| JP2008509928A (ja) | 2008-04-03 |
| TW200608991A (en) | 2006-03-16 |
| EP1796716A2 (en) | 2007-06-20 |
| CA2577046A1 (en) | 2006-02-23 |
| WO2006020891A3 (en) | 2006-07-13 |
| CN101094684A (zh) | 2007-12-26 |
| WO2006020891A2 (en) | 2006-02-23 |
| EP1796716A4 (en) | 2010-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: GENZYME CORPORATION (US) Free format text: TRANSFERIDO DE: ANORMED INC. |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 7A ANUIDADE. |