BRPI0512432A - métodos in vitro e kits de detecção e diferenciação entre mamìfero que apresenta tuberculose latente e mamìfero que apresenta tuberculose ativa e métodos in vitro e kits de detecção e diferenciação entre mamìfero que apresenta tuberculose ativa e mamìfero não infectado por m. tuberculosis ou que apresenta tuberculose latente - Google Patents
métodos in vitro e kits de detecção e diferenciação entre mamìfero que apresenta tuberculose latente e mamìfero que apresenta tuberculose ativa e métodos in vitro e kits de detecção e diferenciação entre mamìfero que apresenta tuberculose ativa e mamìfero não infectado por m. tuberculosis ou que apresenta tuberculose latenteInfo
- Publication number
- BRPI0512432A BRPI0512432A BRPI0512432-8A BRPI0512432A BRPI0512432A BR PI0512432 A BRPI0512432 A BR PI0512432A BR PI0512432 A BRPI0512432 A BR PI0512432A BR PI0512432 A BRPI0512432 A BR PI0512432A
- Authority
- BR
- Brazil
- Prior art keywords
- tuberculosis
- mammal
- detection
- mammals
- infected
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
MéTODOS IN VITRO E KITS DE DETECçãO E DIFERENCIAçãO ENTRE MAMìFERO QUE APRESENTA TUBERCULOSE LATENTE E MAMìFERO QUE APRESENTA TUBERCULOSE ATIVA E MéTODOS IN VITRO E KITS DE DETECçãO E DIFERENCIAçãO ENTRE MAMìFERO QUE APRESENTA TUBERCULOSE ATIVA E MAMìFERO NãO INFECTADO POR M. TUBERCULOSIS OU QUE APRESENTA TUBERCULOSE LATENTE A presente invenção refere-se a métodos de detecção in vitro de infecção por Mycobacterium tuberculosis em mamíferos e métodos de distinção in vitro entre mamíferos infectados com Mycobacterium tuberculosis nos quais a doença é declarada (forma ativa) e mamíferos que são infectados mas assintomáticos para tuberculose (forma latente) e método de distinção in vitro entre mamíferos que apresentam forma ativa de tuberculose e mamíferos não infectados por M. tuberculosis ou que apresentam forma latente de tuberculose. A presente invenção também se refere a kits de detecção e distinção entre mamiferos infectados que apresentam sintomas de tuberculose e mamíferos infectados sem desenvolvimento de doença e kit de diferenciação entre mamíferos que apresentam forma ativa de tuberculose e mamíferos não infectados por M. tuberculosis ou que apresentam forma latente de tuberculose.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0407255A FR2872579B1 (fr) | 2004-06-30 | 2004-06-30 | Detection de la tuberculose et de l'infection par mycobacterium tuberculosis a l'aide de hbha |
| PCT/EP2005/007902 WO2006003029A2 (en) | 2004-06-30 | 2005-06-30 | Detection of tuberculosis and infection by mycobacterium tuberculosis using hbha |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0512432A true BRPI0512432A (pt) | 2008-03-04 |
Family
ID=34948450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0512432-8A BRPI0512432A (pt) | 2004-06-30 | 2005-06-30 | métodos in vitro e kits de detecção e diferenciação entre mamìfero que apresenta tuberculose latente e mamìfero que apresenta tuberculose ativa e métodos in vitro e kits de detecção e diferenciação entre mamìfero que apresenta tuberculose ativa e mamìfero não infectado por m. tuberculosis ou que apresenta tuberculose latente |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7833699B2 (pt) |
| EP (2) | EP1763574A2 (pt) |
| JP (2) | JP2008504539A (pt) |
| CN (2) | CN102253204A (pt) |
| AP (1) | AP2007003882A0 (pt) |
| AU (1) | AU2005259346B2 (pt) |
| BR (1) | BRPI0512432A (pt) |
| CA (1) | CA2572383A1 (pt) |
| ES (1) | ES2523471T3 (pt) |
| FR (1) | FR2872579B1 (pt) |
| RU (1) | RU2426128C2 (pt) |
| WO (1) | WO2006003029A2 (pt) |
| ZA (1) | ZA200700748B (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0229747D0 (en) * | 2002-12-20 | 2003-01-29 | Axis Shield Asa | Assay |
| WO2008078193A2 (en) * | 2006-08-29 | 2008-07-03 | Glycominds Ltd | Method of diagnosing and stratifying anti-phospholipid syndrome |
| WO2009005326A2 (en) | 2007-07-04 | 2009-01-08 | Lg Electronics Inc. | Digital broadcasting system and method of processing data |
| CN103760359B (zh) | 2008-10-21 | 2017-01-11 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| WO2010149657A1 (en) | 2009-06-22 | 2010-12-29 | Px Therapeutics | Method for the purification of hbha |
| EP2483682A1 (en) * | 2009-10-02 | 2012-08-08 | INSERM - Institut National de la Santé et de la Recherche Médicale | Combination of spla2 activity and lp(a) cardiovascular risk factors for the diagnosis/prognosis of a cardiovascular disease/event |
| ES2818138T3 (es) | 2009-12-20 | 2021-04-09 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
| EA201290627A1 (ru) * | 2010-02-05 | 2013-05-30 | Астьют Медикал, Инк. | Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности |
| AU2011220413B2 (en) * | 2010-02-26 | 2015-07-23 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP2013539861A (ja) * | 2010-10-07 | 2013-10-28 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| EP2661620A4 (en) * | 2011-01-08 | 2014-07-16 | Astute Medical Inc | METHOD AND COMPOSITIONS FOR DIAGNOSING AND PROGNOSING RENAL INJURY AND RENAL INSUFFICIENCY |
| EP3133398B1 (en) * | 2011-01-08 | 2020-10-14 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2012103450A2 (en) * | 2011-01-29 | 2012-08-02 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US10935548B2 (en) | 2011-12-08 | 2021-03-02 | Astute Medical, Inc. | Methods for diagnosis and prognosis of renal injury and renal failure using insulin-like growth factor-binding protein 7 and metalloproteinase inhibitor 2 |
| US20130157292A1 (en) * | 2011-12-14 | 2013-06-20 | Paichai University Industry-Academic Cooperation Foundation | Composition for the diagnosis of ovarian cancer or pneumonia comprising thioredoxin 1 as active ingredient and use thereof |
| WO2013113018A1 (en) * | 2012-01-28 | 2013-08-01 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2865559A1 (en) * | 2012-02-27 | 2013-09-06 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US9255924B2 (en) * | 2012-10-12 | 2016-02-09 | University Of Notre Dame Du Lac | Exosomes and diagnostic biomarkers |
| US9841424B2 (en) * | 2012-10-12 | 2017-12-12 | Albert Einstein College Of Medicine, Inc. | Serologic test for the rapid diagnosis of active tuberculosis |
| ES2926197T3 (es) | 2013-01-17 | 2022-10-24 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
| WO2014210327A1 (en) * | 2013-06-27 | 2014-12-31 | The Brigham And Women's Hospital, Inc. | Methods and systems for determining m. tuberculosis infection |
| RU2548765C1 (ru) * | 2013-10-18 | 2015-04-20 | Татьяна Владимировна Клинышкова | Способ диагностики туберкулеза женских гениталий у пациенток с бесплодием |
| CA3026502A1 (en) | 2016-06-06 | 2017-12-14 | Astute Medical, Inc. | Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 |
| RU2702609C1 (ru) * | 2018-08-06 | 2019-10-08 | Федеральное государственное бюджетное учреждение "Новосибирский научно-исследовательский институт туберкулеза" Министерства здравоохранения Российской Федерации (ФГБУ "ННИИТ" Минздрава России) | Способ моделирования туберкулезной инфекции in vitro |
| CN112684184A (zh) * | 2020-12-24 | 2021-04-20 | 中国人民解放军空军特色医学中心 | 一种用于检测结核分枝杆菌潜伏感染的试剂盒 |
| CN112746051A (zh) * | 2020-12-24 | 2021-05-04 | 中国人民解放军空军特色医学中心 | 一种表达甲基化hbha蛋白的重组耻垢分枝杆菌菌株、制备方法及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6338852B1 (en) * | 1995-09-01 | 2002-01-15 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| FR2748748B1 (fr) * | 1996-05-17 | 1998-11-06 | Pasteur Institut | Identification et clonage d'un antigene mycobacterien correspondant a une hemagglutine de liaison a l'heparine |
| ID29858A (id) * | 1998-11-04 | 2001-10-18 | Isis Innovation | Uji diagnostik tuberkulosis |
| JP5010079B2 (ja) * | 1999-07-13 | 2012-08-29 | スタテンズ セーラム インスティテュート | マイコバクテリウム・ツベルクローシスｅｓａｔ−６遺伝子ファミリーベースの結核ワクチン及び診断法 |
| CA2689741C (en) * | 2001-01-08 | 2013-10-01 | The Government Of The United States Of America As Represented By The Sec Retary Of The Department Of Health And Human Services, Centers For Disea | Latent human tuberculosis model, diagnostic antigens, and methods of use |
| FR2832410B1 (fr) * | 2001-11-19 | 2004-04-02 | Pasteur Institut | Antigene mycobacterien recombinant de type hemagglutinine de liaison a l'heparine methylee, procedes de preparation et compositions immunogenes comprenant un tel antigene |
| CN1388378A (zh) * | 2002-06-17 | 2003-01-01 | 四川大学 | 结核分枝杆菌诊断检测试剂 |
-
2004
- 2004-06-30 FR FR0407255A patent/FR2872579B1/fr not_active Expired - Fee Related
-
2005
- 2005-06-30 JP JP2007518561A patent/JP2008504539A/ja not_active Ceased
- 2005-06-30 WO PCT/EP2005/007902 patent/WO2006003029A2/en active Application Filing
- 2005-06-30 CN CN2011100649386A patent/CN102253204A/zh active Pending
- 2005-06-30 EP EP05762329A patent/EP1763574A2/en not_active Withdrawn
- 2005-06-30 ZA ZA200700748A patent/ZA200700748B/en unknown
- 2005-06-30 BR BRPI0512432-8A patent/BRPI0512432A/pt not_active IP Right Cessation
- 2005-06-30 EP EP10190616.2A patent/EP2322932B1/en active Active
- 2005-06-30 CN CNA2005800221037A patent/CN101365949A/zh active Pending
- 2005-06-30 ES ES10190616.2T patent/ES2523471T3/es active Active
- 2005-06-30 CA CA002572383A patent/CA2572383A1/en not_active Abandoned
- 2005-06-30 AP AP2007003882A patent/AP2007003882A0/xx unknown
- 2005-06-30 RU RU2006146922/15A patent/RU2426128C2/ru active
- 2005-06-30 AU AU2005259346A patent/AU2005259346B2/en not_active Ceased
-
2006
- 2006-12-28 US US11/646,299 patent/US7833699B2/en not_active Expired - Fee Related
-
2011
- 2011-02-02 JP JP2011020605A patent/JP2011095275A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005259346A1 (en) | 2006-01-12 |
| EP2322932A3 (en) | 2011-11-09 |
| CN101365949A (zh) | 2009-02-11 |
| JP2011095275A (ja) | 2011-05-12 |
| US7833699B2 (en) | 2010-11-16 |
| FR2872579A1 (fr) | 2006-01-06 |
| AP2007003882A0 (en) | 2007-02-28 |
| EP2322932B1 (en) | 2014-08-13 |
| ES2523471T3 (es) | 2014-11-26 |
| AU2005259346B2 (en) | 2012-02-09 |
| WO2006003029A2 (en) | 2006-01-12 |
| CA2572383A1 (en) | 2006-01-12 |
| US20070212740A1 (en) | 2007-09-13 |
| EP1763574A2 (en) | 2007-03-21 |
| EP2322932A2 (en) | 2011-05-18 |
| FR2872579B1 (fr) | 2006-11-24 |
| RU2426128C2 (ru) | 2011-08-10 |
| RU2006146922A (ru) | 2008-08-10 |
| ZA200700748B (en) | 2008-05-28 |
| CN102253204A (zh) | 2011-11-23 |
| JP2008504539A (ja) | 2008-02-14 |
| WO2006003029A3 (en) | 2007-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2312 DE 28-04-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |