BRPI0512413A - derivados de polissacarìdeo e usos na indução de uma resposta imune - Google Patents

derivados de polissacarìdeo e usos na indução de uma resposta imune

Info

Publication number
BRPI0512413A
BRPI0512413A BRPI0512413-1A BRPI0512413A BRPI0512413A BR PI0512413 A BRPI0512413 A BR PI0512413A BR PI0512413 A BRPI0512413 A BR PI0512413A BR PI0512413 A BRPI0512413 A BR PI0512413A
Authority
BR
Brazil
Prior art keywords
des
acetylated
derivatives
derivative
immune response
Prior art date
Application number
BRPI0512413-1A
Other languages
English (en)
Portuguese (pt)
Inventor
Gregory R Moe
Dan M Granoff
Original Assignee
Childrens Hosp & Res Ct Oak
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Hosp & Res Ct Oak filed Critical Childrens Hosp & Res Ct Oak
Publication of BRPI0512413A publication Critical patent/BRPI0512413A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/36—Neisseria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0512413-1A 2004-06-23 2005-06-23 derivados de polissacarìdeo e usos na indução de uma resposta imune BRPI0512413A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58267204P 2004-06-23 2004-06-23
PCT/US2005/022590 WO2006002402A2 (en) 2004-06-23 2005-06-23 Polysaccharide derivatives and uses in induction of an immune response

Publications (1)

Publication Number Publication Date
BRPI0512413A true BRPI0512413A (pt) 2008-03-04

Family

ID=35782376

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512413-1A BRPI0512413A (pt) 2004-06-23 2005-06-23 derivados de polissacarìdeo e usos na indução de uma resposta imune

Country Status (14)

Country Link
US (2) US7595307B2 (https=)
EP (1) EP1784428A2 (https=)
JP (1) JP2008509886A (https=)
KR (1) KR20070060069A (https=)
AU (1) AU2005258301A1 (https=)
BR (1) BRPI0512413A (https=)
CA (1) CA2568982A1 (https=)
CR (1) CR8862A (https=)
EC (1) ECSP077129A (https=)
IL (1) IL179642A0 (https=)
MX (1) MXPA06015107A (https=)
NO (1) NO20070434L (https=)
RU (1) RU2404995C2 (https=)
WO (1) WO2006002402A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595307B2 (en) 2004-06-23 2009-09-29 Children's Hospital And Research Center At Oakland Polysaccharide derivatives and uses in induction of an immune response
US8148335B2 (en) 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
AU2006283302B2 (en) * 2005-08-24 2012-11-15 Novartis Vaccines And Diagnostics Srl Zwitterionization of capsular saccharides
MX2008008185A (es) * 2005-12-23 2008-11-14 Childrens Hosp & Res Ct Oak Antigenos de acido des-n-acetil-sialico, anticuerpos para los mismos, y metodos de uso en la terapia de cancer.
EP2170391B1 (en) * 2007-06-20 2017-01-18 Pfizer Ireland Pharmaceuticals Modified polysaccharides for conjugate vaccines
EP2173759A4 (en) * 2007-07-03 2014-01-29 Childrens Hosp & Res Ct Oak OLIGOSIAL INSERTS, PROCESS FOR THEIR PREPARATION AND ITS IMMUNOLOGICAL USE
CA2692419C (en) * 2007-07-03 2017-12-05 Children's Hospital & Research Center At Oakland Inhibitors of polysialic acid de-n-acetylase and methods for using the same
JP5523313B2 (ja) * 2007-07-03 2014-06-18 チルドレンズ ホスピタル アンド リサーチ センター アット オークランド ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用
CA2797052A1 (en) 2010-04-23 2011-10-27 Ancora Pharmaceuticals Inc. Synthetic oligosaccharides for staphyloccocus vaccine
US8716469B2 (en) 2010-04-27 2014-05-06 Ancora Pharmaceuticals, Inc. Synthetic oligosaccharides for Moraxella vaccine
WO2011149778A1 (en) 2010-05-26 2011-12-01 Ancora Pharmaceuticals Inc. Synthetic oligosaccharides for neisseria meningitis vaccine
CN109182423B (zh) * 2018-09-26 2020-07-07 武汉中科光谷绿色生物技术有限公司 促进大肠杆菌发酵生产聚唾液酸的方法
CN112795583A (zh) * 2020-11-16 2021-05-14 上海大学 重组唾液酸外切酶的制备方法、表达基因、重组表达载体及构建方法
CN114507262B (zh) * 2022-03-01 2023-12-19 德元堂(上海)健康科技发展有限公司 一种聚唾液酸的水解工艺
CN114539333B (zh) * 2022-03-01 2023-12-22 德元堂(上海)健康科技发展有限公司 一种唾液酸的循环生产工艺

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314999A (en) * 1978-07-31 1982-02-09 Proter S.P.A. N-Acyl derivatives of glucosamine having antitumor chemotherapeutic acitivity
US4216208A (en) * 1978-07-31 1980-08-05 Proter S.P.A. N-Acyl derivatives of glucosamines having antitumor chemotherapeutic activity
US4727136A (en) 1985-10-01 1988-02-23 Canadian Patents And Development Ltd. Modified meningococcal group B polysaccharide for conjugate vaccine
US4722136A (en) * 1985-10-28 1988-02-02 Leviton Manufacturing Company, Inc. Snap-in convenience electrical connector system and method of assembly
JPS6344590A (ja) * 1986-08-12 1988-02-25 Mect Corp シアル酸誘導体の製造方法
DE69019164T2 (de) 1989-12-14 1995-09-07 National Research Council Of Canada, Ottawa, Ontario Verbessertes meningokokkale polysaccharidkonjugatvakzin.
US5846951A (en) * 1991-06-06 1998-12-08 The School Of Pharmacy, University Of London Pharmaceutical compositions
GB9116896D0 (en) * 1991-08-06 1991-09-18 Erba Carlo Spa 3-deoxymannosamine derivatives and process for their preparation
US5811102A (en) * 1995-06-07 1998-09-22 National Research Council Of Canada Modified meningococcal polysaccharide conjugate vaccines
JPH101397A (ja) * 1996-06-14 1998-01-06 Mitsubishi Gas Chem Co Inc 磁気光学素子の基板用ガーネット結晶及びその製造法
US6048527A (en) 1996-08-27 2000-04-11 Chiron Corporation Antibodies that define unique Meningococcal B epitopes and vaccine compositions
ES2166097T5 (es) * 1996-08-27 2007-03-16 Novartis Vaccines And Diagnostics, Inc. Glicoconjugados de neisseria meningitidis de serogrupo b y procedimientos para usarlos.
CA2301942C (en) 1997-08-27 2011-05-31 Chiron Corporation Molecular mimetics of meningococcal b epitopes
AU5339699A (en) * 1998-08-06 2000-02-28 Johns Hopkins University School Of Medicine, The Compounds for altering cell surface sialic acids and methods of use therefor
CA2279134A1 (en) * 1999-07-29 2001-01-29 Tianmin Liu Novel strategy for carbohydrate-based therapeutic vaccines
EP1307221A2 (en) 2000-07-28 2003-05-07 National Research Council of Canada Modified sialic acid vaccines
US7595307B2 (en) 2004-06-23 2009-09-29 Children's Hospital And Research Center At Oakland Polysaccharide derivatives and uses in induction of an immune response

Also Published As

Publication number Publication date
US20070010482A1 (en) 2007-01-11
JP2008509886A (ja) 2008-04-03
KR20070060069A (ko) 2007-06-12
WO2006002402A2 (en) 2006-01-05
CR8862A (es) 2007-07-24
US7595307B2 (en) 2009-09-29
US20100068728A1 (en) 2010-03-18
IL179642A0 (en) 2007-05-15
EP1784428A2 (en) 2007-05-16
AU2005258301A1 (en) 2006-01-05
RU2007102255A (ru) 2008-07-27
NO20070434L (no) 2007-03-20
RU2404995C2 (ru) 2010-11-27
ECSP077129A (https=) 2007-02-28
MXPA06015107A (es) 2007-03-26
CA2568982A1 (en) 2006-01-05
WO2006002402A3 (en) 2006-05-04

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.