BRPI0510632A - fosfatos de cálcio de hidroxiapatita, seu método de preparação e suas aplicações - Google Patents

fosfatos de cálcio de hidroxiapatita, seu método de preparação e suas aplicações

Info

Publication number
BRPI0510632A
BRPI0510632A BRPI0510632-0A BRPI0510632A BRPI0510632A BR PI0510632 A BRPI0510632 A BR PI0510632A BR PI0510632 A BRPI0510632 A BR PI0510632A BR PI0510632 A BRPI0510632 A BR PI0510632A
Authority
BR
Brazil
Prior art keywords
applications
calcium phosphates
preparation
calcium phosphate
brushitic
Prior art date
Application number
BRPI0510632-0A
Other languages
English (en)
Inventor
John Godber
Lorraine Leite
Original Assignee
Innophos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innophos Inc filed Critical Innophos Inc
Publication of BRPI0510632A publication Critical patent/BRPI0510632A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/327—After-treatment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Environmental & Geological Engineering (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)

Abstract

FOSFATOS DE CáLCIO DE HIDROXIAPATITA, SEU MéTODO DE PREPARAçãO E SUAS APLICAçõES. A presente invenção refere-se a fosfatos de cálcio na forma granular, tendo um padrão de difração de raios X característico de hidroxiapatita, no qual uma parte dos ânions da treliça cristalina é substituída por ânions carbonato, e que têm boas propriedades de compressibilidade e fluxo em aplicações de compressão direta. A invenção refere-se também aos métodos para preparar os grânulos de fosfato de cálcio supramencionados, distinguido pelo fato de que os métodos incluem o processamento de uma solução de fosfato dicálcico brushítico que tem uma distribuição de tamanho de partícula especificada, usando uma solução de um carbonato de metal alcalinoterroso por um período de tempo suficiente para permitir a transformação do fosfato de cálcio brushítico em fosfato de cálcio hidroxiapatítico.
BRPI0510632-0A 2004-05-06 2005-05-06 fosfatos de cálcio de hidroxiapatita, seu método de preparação e suas aplicações BRPI0510632A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0404900A FR2869893B1 (fr) 2004-05-06 2004-05-06 Nouveaux granules de phosphates de calcium de type hydroxyapatite, leur procede de preparation et leurs applications
PCT/US2005/015684 WO2005115418A2 (en) 2004-05-06 2005-05-06 New hydroxapatite calcium phosphates, their method of preparation and their applications

Publications (1)

Publication Number Publication Date
BRPI0510632A true BRPI0510632A (pt) 2007-11-13

Family

ID=34946835

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510632-0A BRPI0510632A (pt) 2004-05-06 2005-05-06 fosfatos de cálcio de hidroxiapatita, seu método de preparação e suas aplicações

Country Status (11)

Country Link
US (2) US7468172B2 (pt)
EP (1) EP1753438A4 (pt)
JP (1) JP2008501643A (pt)
KR (1) KR100868130B1 (pt)
AU (1) AU2005247339B2 (pt)
BR (1) BRPI0510632A (pt)
CA (1) CA2563816C (pt)
FR (1) FR2869893B1 (pt)
MX (1) MXPA06012843A (pt)
NZ (1) NZ550737A (pt)
WO (1) WO2005115418A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100934289B1 (ko) * 2007-12-11 2009-12-29 재단법인서울대학교산학협력재단 하이드록시아파타이트 세라믹의 표면 개질방법
US9211529B2 (en) 2009-09-11 2015-12-15 E I Du Pont De Nemours And Company Conversion of ethanol to a reaction product comprising 1-butanol using hydroxyapatite catalysts
BR112012005321B1 (pt) * 2009-09-11 2018-06-05 E.I. Du Pont De Nemours And Company "Processo"
US20130338237A1 (en) 2010-12-31 2013-12-19 Ahmet Cuneyt Tas Preparation of brushite and octacalcium phosphate granules
US11805784B2 (en) 2015-05-18 2023-11-07 Ndg Natural Development Group S.R.L. Use of hydroxyapatite as a carrier of bioactive substances for treating vascular diseases in plants
ITUB20150693A1 (it) * 2015-05-18 2016-11-18 Ndg Natural Dev Group S R L Uso di idrossiapatite come veicolo di sostanze bioattive per trattare malattie vascolari nelle piante
US9776883B2 (en) 2015-09-25 2017-10-03 Clean World Technologies Ltd. Producing calcium oxides
WO2018198296A1 (ja) * 2017-04-27 2018-11-01 ブレイニー株式会社 ハイドロキシアパタイト、化粧品及び食品、並びにその製造方法
JP6936450B2 (ja) * 2017-05-19 2021-09-15 富士通株式会社 光触媒、及びその製造方法、部材、並びに装置

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JPS609713B2 (ja) * 1976-10-08 1985-03-12 大塚製薬株式会社 カルボスチリル誘導体
FR2509612A1 (fr) * 1981-07-20 1983-01-21 Fabre Sa Pierre Composition pharmaceutique anti-reflux et anti-acide
US4355086A (en) * 1981-10-01 1982-10-19 Honeywell Inc. Lithium thionyl chloride battery
US4460581A (en) * 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
JPS61151011A (ja) * 1984-12-25 1986-07-09 Central Glass Co Ltd 炭酸含有ヒドロキシアパタイトの製造法
US4707361A (en) * 1985-08-02 1987-11-17 Stauffer Chemical Company Granular anhydrous dicalcium phosphate compositions suitable for direct compression tableting
JPS6287406A (ja) * 1985-10-11 1987-04-21 Agency Of Ind Science & Technol β−リン酸三カルシウムの製造方法
JPS62223010A (ja) * 1986-03-25 1987-10-01 Taihei Kagaku Sangyo Kk 水酸アパタイトの製造方法
JPS62223011A (ja) * 1986-03-25 1987-10-01 Taihei Kagaku Sangyo Kk 第三リン酸カルシウムの製造方法
US4891198A (en) * 1986-08-07 1990-01-02 General Foods Corporation Preparation of tricalcium phosphate
JPS63176347A (ja) * 1987-01-12 1988-07-20 科学技術庁無機材質研究所長 アパタイト多孔体の製造方法
JPS63225509A (ja) * 1987-03-13 1988-09-20 Natl Inst For Res In Inorg Mater 炭酸アパタイト粉体の製造方法
US4894219A (en) * 1988-03-29 1990-01-16 University Of Florida Beta-agonist carbostyril derivatives, assay method and pharmacological composition
US6117456A (en) * 1995-05-19 2000-09-12 Etex Corporation Methods and products related to the physical conversion of reactive amorphous calcium phosphate
JP3641298B2 (ja) * 1995-07-27 2005-04-20 太平化学産業株式会社 板状ヒドロキシアパタイト大型結晶の製造方法
JP2896498B2 (ja) * 1996-07-31 1999-05-31 工業技術院長 ａ面を成長させた板状水酸アパタイトの製造方法
GB9727048D0 (en) * 1997-12-22 1998-02-18 Abonetics Ltd Process for the preparation of magnesium and carbonate substituted hydroxyapatite
GB9727049D0 (en) * 1997-12-22 1998-02-18 Abonetics Ltd Method for the preparation of carbonated hydroxyapatite compositions
JP2000143443A (ja) * 1998-11-02 2000-05-23 Sekisui Plastics Co Ltd ヒドロキシアパタイト顔料とその製造方法および化粧料
FR2799193B1 (fr) * 1999-10-04 2002-03-15 Toulouse Inst Nat Polytech Procede d'obtention de poudre d'apatite de composition chimique definie et de granulometrie controlee
US20040180091A1 (en) * 2003-03-13 2004-09-16 Chang-Yi Lin Carbonated hydroxyapatite-based microspherical composites for biomedical uses
FR2857658B1 (fr) * 2003-07-16 2006-09-22 Rhodia Chimie Sa Nouveaux granules de phosphates de calcium de type hydroxyapatite, leur procede de preparation et leurs applications

Also Published As

Publication number Publication date
AU2005247339A1 (en) 2005-12-08
KR20070027574A (ko) 2007-03-09
KR100868130B1 (ko) 2008-11-10
WO2005115418A9 (en) 2006-03-09
AU2005247339B2 (en) 2009-01-08
US7767300B2 (en) 2010-08-03
MXPA06012843A (es) 2007-02-15
US20050271571A1 (en) 2005-12-08
EP1753438A2 (en) 2007-02-21
US7468172B2 (en) 2008-12-23
US20090130444A1 (en) 2009-05-21
CA2563816C (en) 2011-07-12
WO2005115418A3 (en) 2007-06-07
CA2563816A1 (en) 2005-12-08
FR2869893B1 (fr) 2006-07-28
JP2008501643A (ja) 2008-01-24
EP1753438A4 (en) 2011-12-28
WO2005115418A2 (en) 2005-12-08
NZ550737A (en) 2010-08-27
FR2869893A1 (fr) 2005-11-11

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: PAGAR RESTAURACAO.

B08H Application fees: decision cancelled [chapter 8.8 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2257 DE 08/04/2014

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI