BRPI0510411A - derivados de dióxido de oxazol-benzoisotiazol, processos para a sua fabricação e seu uso - Google Patents

derivados de dióxido de oxazol-benzoisotiazol, processos para a sua fabricação e seu uso

Info

Publication number
BRPI0510411A
BRPI0510411A BRPI0510411-4A BRPI0510411A BRPI0510411A BR PI0510411 A BRPI0510411 A BR PI0510411A BR PI0510411 A BRPI0510411 A BR PI0510411A BR PI0510411 A BRPI0510411 A BR PI0510411A
Authority
BR
Brazil
Prior art keywords
processes
oxazol
manufacture
dioxide derivatives
compounds
Prior art date
Application number
BRPI0510411-4A
Other languages
English (en)
Inventor
Stefan Petry
Norbert Tennagels
Reinhard Kirsch
Karl-Heinz Baringhaus
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of BRPI0510411A publication Critical patent/BRPI0510411A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

DERIVADOS DE DIóXIDO DE OXAZOL-BENZO-ISOTIAZOL, PROCESSOS PARA A SUA FABRICAçãO E SEU USO. A presente invenção refere-se a derivados de dióxido de benzoi-sotiazol substituídos, processos para sua fabricação e seu uso. A invenção refere-se aos compostos da fórmula (I), na qual os radicais têm os significados indicados, bem como seus sais fisiologicamente toleráveis. Os compostos prestam-se por exemplo, como medicamentos para a diminuição da glicose e para a prevenção e tratamento de diabetes.
BRPI0510411-4A 2004-05-29 2005-05-14 derivados de dióxido de oxazol-benzoisotiazol, processos para a sua fabricação e seu uso BRPI0510411A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004026532A DE102004026532A1 (de) 2004-05-29 2004-05-29 Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
PCT/EP2005/005321 WO2005116003A2 (de) 2004-05-29 2005-05-14 Substituierte oxazol-benzoisothiazoldioxidderivate, verfahren zu deren herstellung und deren verwendung

Publications (1)

Publication Number Publication Date
BRPI0510411A true BRPI0510411A (pt) 2007-10-23

Family

ID=34979116

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510411-4A BRPI0510411A (pt) 2004-05-29 2005-05-14 derivados de dióxido de oxazol-benzoisotiazol, processos para a sua fabricação e seu uso

Country Status (20)

Country Link
US (1) US7453000B2 (pt)
EP (1) EP1753761B1 (pt)
JP (1) JP2008500976A (pt)
CN (1) CN100594214C (pt)
AR (1) AR048974A1 (pt)
AU (1) AU2005247565A1 (pt)
BR (1) BRPI0510411A (pt)
CA (1) CA2568578A1 (pt)
DE (1) DE102004026532A1 (pt)
IL (1) IL179424A0 (pt)
MA (1) MA28600B1 (pt)
MX (1) MXPA06013818A (pt)
MY (1) MY137477A (pt)
NO (1) NO20065926L (pt)
NZ (1) NZ551624A (pt)
PA (1) PA8635301A1 (pt)
RU (1) RU2377242C2 (pt)
TW (1) TW200604193A (pt)
WO (1) WO2005116003A2 (pt)
ZA (1) ZA200608438B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE529405T1 (de) 2006-03-31 2011-11-15 Novartis Ag (4-(4-ä6-(trifluoromethyl-pyridin-3-ylamino)-n- enthaltend-heteroarylü-phenyl)-cyclohexyl)- essigsäure-derivate und ihre pharmazeutische anwendungen
MX2009001043A (es) 2006-08-08 2009-02-06 Sanofi Aventis Imidazolidina-2,4-dionas sustituidas con arilaminoarilalquilo, procedimiento para preparalas, medicamentos que comprenden estos compuestos y su uso.
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
AR072707A1 (es) 2008-07-09 2010-09-15 Sanofi Aventis Compuestos heterociclicos, procesos para su preparacion, medicamentos que comprenden estos compuestos y el uso de los mismos
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
ES2443016T3 (es) 2009-08-26 2014-02-17 Sanofi Nuevos hidratos cristalinos de fluoroglicósidos heteroaromáticos, productos farmacéuticos que comprenden estos compuestos, y su empleo
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
WO2012120051A1 (de) 2011-03-08 2012-09-13 Sanofi Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683702B1 (de) 2011-03-08 2014-12-24 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8846666B2 (en) 2011-03-08 2014-09-30 Sanofi Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2683700B1 (de) 2011-03-08 2015-02-18 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120057A1 (de) 2011-03-08 2012-09-13 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120055A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
JP6625057B2 (ja) * 2014-01-14 2019-12-25 コネクシャス ライフ サイエンシス ピーヴィティー リミテッドＣｏｎｎｅｘｉｏｓ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｐｖｔ． Ｌｔｄ． Ｒｘｒアゴニストとしての置換二環式ヘテロアリール化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04128276A (ja) * 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd アミノベンゾサルタム誘導体およびその用途
PE20011124A1 (es) * 2000-03-31 2001-10-28 Upjohn Co Nuevos agentes antibacterianos de benzosultam oxazolidinona
DE10038709A1 (de) * 2000-08-09 2002-02-28 Aventis Pharma Gmbh Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen
DE10142734A1 (de) * 2001-08-31 2003-03-27 Aventis Pharma Gmbh Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10334309A1 (de) * 2003-07-28 2005-03-03 Aventis Pharma Deutschland Gmbh Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung

Also Published As

Publication number Publication date
CN1960989A (zh) 2007-05-09
TW200604193A (en) 2006-02-01
AR048974A1 (es) 2006-06-14
RU2377242C2 (ru) 2009-12-27
WO2005116003A3 (de) 2006-01-05
JP2008500976A (ja) 2008-01-17
PA8635301A1 (es) 2006-01-23
DE102004026532A1 (de) 2006-01-05
MA28600B1 (fr) 2007-05-02
US20070149511A1 (en) 2007-06-28
EP1753761A2 (de) 2007-02-21
NZ551624A (en) 2009-07-31
NO20065926L (no) 2007-02-12
AU2005247565A1 (en) 2005-12-08
IL179424A0 (en) 2007-05-15
CN100594214C (zh) 2010-03-17
RU2006147245A (ru) 2008-07-10
US7453000B2 (en) 2008-11-18
MXPA06013818A (es) 2007-03-01
ZA200608438B (en) 2008-04-30
CA2568578A1 (en) 2005-12-08
EP1753761B1 (de) 2014-04-30
WO2005116003A2 (de) 2005-12-08
MY137477A (en) 2009-01-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.