BRPI0510143A - processo para a preparação de produtos quìmicos e farmacêuticos com cromatografia integrada de colunas múltiplas - Google Patents

processo para a preparação de produtos quìmicos e farmacêuticos com cromatografia integrada de colunas múltiplas

Info

Publication number
BRPI0510143A
BRPI0510143A BRPI0510143-3A BRPI0510143A BRPI0510143A BR PI0510143 A BRPI0510143 A BR PI0510143A BR PI0510143 A BRPI0510143 A BR PI0510143A BR PI0510143 A BRPI0510143 A BR PI0510143A
Authority
BR
Brazil
Prior art keywords
preparation
chemicals
column chromatography
multiple column
pharmaceuticals
Prior art date
Application number
BRPI0510143-3A
Other languages
English (en)
Inventor
Jochen Strube
Karsten-Ulrich Klatt
Gerhard Noeth
Joern Greifenberg
Sebastian B Cker
Heinz Kansy
Peter John
Berthold Justen
Original Assignee
Bayer Technology Services Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Technology Services Gmbh filed Critical Bayer Technology Services Gmbh
Publication of BRPI0510143A publication Critical patent/BRPI0510143A/pt
Publication of BRPI0510143B1 publication Critical patent/BRPI0510143B1/pt

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K27/00—Construction of housing; Use of materials therefor
    • F16K27/003—Housing formed from a plurality of the same valve elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/1842—Simulated moving beds characterized by apparatus features
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
    • F16B11/00—Connecting constructional elements or machine parts by sticking or pressing them together, e.g. cold pressure welding
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16D—COUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
    • F16D1/00—Couplings for rigidly connecting two coaxial shafts or other movable machine elements
    • F16D1/06—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end
    • F16D1/064—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end non-disconnectable
    • F16D1/068—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end non-disconnectable involving gluing, welding or the like
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16D—COUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
    • F16D3/00—Yielding couplings, i.e. with means permitting movement between the connected parts during the drive
    • F16D3/16—Universal joints in which flexibility is produced by means of pivots or sliding or rolling connecting parts
    • F16D3/26—Hooke's joints or other joints with an equivalent intermediate member to which each coupling part is pivotally or slidably connected
    • F16D3/38—Hooke's joints or other joints with an equivalent intermediate member to which each coupling part is pivotally or slidably connected with a single intermediate member with trunnions or bearings arranged on two axes perpendicular to one another
    • F16D3/382—Hooke's joints or other joints with an equivalent intermediate member to which each coupling part is pivotally or slidably connected with a single intermediate member with trunnions or bearings arranged on two axes perpendicular to one another constructional details of other than the intermediate member
    • F16D3/387—Fork construction; Mounting of fork on shaft; Adapting shaft for mounting of fork
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/42—Flow patterns using counter-current
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16D—COUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
    • F16D1/00—Couplings for rigidly connecting two coaxial shafts or other movable machine elements
    • F16D1/06—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end
    • F16D2001/062—Couplings for rigidly connecting two coaxial shafts or other movable machine elements for attachment of a member on a shaft or on a shaft-end characterised by adaptors where hub bores being larger than the shaft
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/6851—With casing, support, protector or static constructional installations
    • Y10T137/7043—Guards and shields
    • Y10T137/7062—Valve guards

Abstract

PROCESSO PARA A PREPARAçãO DE PRODUTOS QUìMICOS E FARMACêUTICOS COM CROMATOGRAFIA INTEGRADA DE COLUNAS MúLTIPLAS. A invenção refere-se a um processo para a separação de substâncias na preparação de produtos químicos como, por exemplo, produtos farmacêuticos quirais, isómeros ou biomoleculares em pequena ou em grande escala, com base na tecnologia "Simulated Moving Bed" (SMB = cromatografia de contracorrente).
BRPI0510143-3A 2004-05-21 2005-05-14 A method for separating a mixture of substances by means of a simulated moving bed chromatography (LMS) BRPI0510143B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004025000.6 2004-05-21
DE200410025000 DE102004025000A1 (de) 2004-05-21 2004-05-21 Verfahren zur Herstellung von chemischen und pharmazeutischen Produkten mit integrierter Mehrsäulen-Chromatographie
PCT/EP2005/005313 WO2005113101A2 (de) 2004-05-21 2005-05-14 Verfahren zur herstellung von chemischen und pharmazeutischen produkten mit integrierter mehrsäulen-chromatographie

Publications (2)

Publication Number Publication Date
BRPI0510143A true BRPI0510143A (pt) 2007-10-02
BRPI0510143B1 BRPI0510143B1 (pt) 2017-12-19

Family

ID=34967690

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510143-3A BRPI0510143B1 (pt) 2004-05-21 2005-05-14 A method for separating a mixture of substances by means of a simulated moving bed chromatography (LMS)

Country Status (11)

Country Link
US (2) US7615159B2 (pt)
EP (2) EP1753517B1 (pt)
JP (3) JP5021466B2 (pt)
CN (2) CN101321567B (pt)
BR (1) BRPI0510143B1 (pt)
DE (1) DE102004025000A1 (pt)
HK (1) HK1127311A1 (pt)
IL (1) IL179451A (pt)
MX (1) MXPA06013419A (pt)
NO (1) NO340260B1 (pt)
WO (1) WO2005113101A2 (pt)

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FR2976500B1 (fr) * 2011-06-16 2013-05-31 IFP Energies Nouvelles Procede et dispositif de sepation chromatographique a contre-courant simule a faible perte de charge et nombre de zones eleve.
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CN104415573B (zh) * 2013-09-10 2017-03-22 中国科学院大连化学物理研究所 一种延胡索提取物中叔胺碱和季铵碱的分类制备方法
JP6902041B2 (ja) 2016-01-27 2021-07-14 コーク−グリッシュ，リミティド パートナーシップ 剛性向上用内部梁を有するインレットベーン装置及びそれを備える容器
DE102017107089B4 (de) 2017-04-03 2019-08-22 Karlsruher Institut für Technologie Vorrichtung und Verfahren zur selektiven Fraktionierung von Feinstpartikeln
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KR20210116656A (ko) 2019-02-05 2021-09-27 스웨이지락 캄파니 다중 밸브 조립체를 위한 통합 액추에이터 매니폴드
US11867673B2 (en) 2019-03-22 2024-01-09 Indian Institute Of Technology Delhi NIR based real-time control of loading in protein a chromatography
CN111841073B (zh) * 2019-09-12 2022-02-22 浙江大学宁波理工学院 从原料中分离与浓缩目标组分的多柱切换循环色谱分离系统及其方法

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Also Published As

Publication number Publication date
IL179451A (en) 2011-07-31
MXPA06013419A (es) 2007-01-23
IL179451A0 (en) 2007-05-15
CN101321567A (zh) 2008-12-10
CN103157294A (zh) 2013-06-19
EP2336617A2 (de) 2011-06-22
JP5122679B2 (ja) 2013-01-16
JP5021466B2 (ja) 2012-09-05
WO2005113101A3 (de) 2008-04-17
HK1127311A1 (en) 2009-09-25
EP2336617A3 (de) 2012-09-12
CN103157294B (zh) 2015-07-29
WO2005113101A2 (de) 2005-12-01
US8658040B2 (en) 2014-02-25
DE102004025000A1 (de) 2005-12-08
NO340260B1 (no) 2017-03-27
CN101321567B (zh) 2013-03-06
WO2005113101A8 (de) 2008-07-17
JP2012115832A (ja) 2012-06-21
EP1753517A2 (de) 2007-02-21
JP2011174941A (ja) 2011-09-08
NO20065865L (no) 2007-02-21
JP5122667B2 (ja) 2013-01-16
US20080135483A1 (en) 2008-06-12
US20090294364A1 (en) 2009-12-03
US7615159B2 (en) 2009-11-10
EP2336617B1 (de) 2014-02-26
EP1753517B1 (de) 2013-07-10
BRPI0510143B1 (pt) 2017-12-19
JP2008500544A (ja) 2008-01-10

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Owner name: BAYER AKTIENGESELLSCHAFT (DE)

B15K Others concerning applications: alteration of classification

Ipc: B01D 15/10 (2006.01), G01N 30/46 (2006.01)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
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B25A Requested transfer of rights approved
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