BRPI0509339A - implantes intraoculares de liberação sustentada compreendendo um antagonista do receptor beta adrenérgico e métodos para tratar neuropatias oculares - Google Patents

implantes intraoculares de liberação sustentada compreendendo um antagonista do receptor beta adrenérgico e métodos para tratar neuropatias oculares

Info

Publication number
BRPI0509339A
BRPI0509339A BRPI0509339-2A BRPI0509339A BRPI0509339A BR PI0509339 A BRPI0509339 A BR PI0509339A BR PI0509339 A BRPI0509339 A BR PI0509339A BR PI0509339 A BRPI0509339 A BR PI0509339A
Authority
BR
Brazil
Prior art keywords
receptor antagonist
adrenergic receptor
beta adrenergic
methods
sustained release
Prior art date
Application number
BRPI0509339-2A
Other languages
English (en)
Inventor
Glenn T Huang
Thierry Nivaggioli
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of BRPI0509339A publication Critical patent/BRPI0509339A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

IMPLANTES INTRAOCULARES DE LIBERAçãO SUSTENTADA COMPREENDENDO UM ANTAGONISTA DO RECEPTOR BETA ADRENéRGICO E MéTODOS PARA TRATAR NEUROPATIAS OCULARES. Os implantes intra-oculares incluem um antagonista do receptor beta adrenérgico e um polímero associado com o antagonista do receptor beta adrenérgico para facilitar a liberação do antagnoista do receptor beta adrenérgico em um olho durante um período prolongado de tempo. O antagonista do receptor beta adrenérgico pode estar associado com uma matriz de polímero biodegradável, tal como uma matriz de dois polímeros biodegradáveis. Os implantes podem ser colocados em um olho para tratar uma ou mais condições oculares, tais como uma neuropatia ocular, por exemplo, várias formas de glaucoma.
BRPI0509339-2A 2004-04-30 2005-04-21 implantes intraoculares de liberação sustentada compreendendo um antagonista do receptor beta adrenérgico e métodos para tratar neuropatias oculares BRPI0509339A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/836,880 US20050244458A1 (en) 2004-04-30 2004-04-30 Sustained release intraocular implants and methods for treating ocular neuropathies
PCT/US2005/014021 WO2005110380A1 (en) 2004-04-30 2005-04-21 Sustained release intraocular implants comprising a beta adrenergic receptor antagonist and methods for treating ocular neuropathies

Publications (1)

Publication Number Publication Date
BRPI0509339A true BRPI0509339A (pt) 2007-07-24

Family

ID=34967183

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509339-2A BRPI0509339A (pt) 2004-04-30 2005-04-21 implantes intraoculares de liberação sustentada compreendendo um antagonista do receptor beta adrenérgico e métodos para tratar neuropatias oculares

Country Status (9)

Country Link
US (3) US20050244458A1 (pt)
EP (2) EP1748766B1 (pt)
JP (2) JP2007535539A (pt)
AU (1) AU2005244211B2 (pt)
BR (1) BRPI0509339A (pt)
CA (1) CA2565347C (pt)
DK (1) DK2361617T3 (pt)
ES (1) ES2499541T3 (pt)
WO (1) WO2005110380A1 (pt)

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WO2005110380A1 (en) 2005-11-24
AU2005244211B2 (en) 2011-05-26
US20050244458A1 (en) 2005-11-03
EP1748766B1 (en) 2014-06-11
CA2565347C (en) 2014-01-28
JP2013126997A (ja) 2013-06-27
US8715709B2 (en) 2014-05-06
ES2499541T3 (es) 2014-09-29
DK2361617T3 (da) 2014-09-22
JP2007535539A (ja) 2007-12-06
US20110091520A1 (en) 2011-04-21
CA2565347A1 (en) 2005-11-24
EP1748766A1 (en) 2007-02-07
EP2361617B1 (en) 2014-06-11
EP2361617A1 (en) 2011-08-31
AU2005244211A1 (en) 2005-11-24

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