BRPI0507647A - bactéria produtora de l-treonina pertencente ao gênero escherichia, e, método para produzir l-treonina - Google Patents
bactéria produtora de l-treonina pertencente ao gênero escherichia, e, método para produzir l-treoninaInfo
- Publication number
- BRPI0507647A BRPI0507647A BRPI0507647-1A BRPI0507647A BRPI0507647A BR PI0507647 A BRPI0507647 A BR PI0507647A BR PI0507647 A BRPI0507647 A BR PI0507647A BR PI0507647 A BRPI0507647 A BR PI0507647A
- Authority
- BR
- Brazil
- Prior art keywords
- threonine
- producing
- bacterium belonging
- genus escherichia
- genus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
BACTéRIA PRODUTORA DE L-TREONINA PERTENCENTE AO GêNERO ESCHERICHIA, E, MéTODO PARA PRODUZIR L-TREONINA é descrito um método para produzir L-treonina usando bactéria pertencente do gênero Escherichia no qual a bactéria possui produtividade de L-treonina e tem sido modificada para ter expressão intensificada de um ou mais genes, selecionados do grupo consistindo de genes glk, pgi, pfkA, tpiA, gapA, pgk, eno, e pykA, codificadores de enzimas da rota glicolítica.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2004103986/13A RU2288264C2 (ru) | 2004-02-12 | 2004-02-12 | Бактерия, принадлежащая к роду escherichia - продуцент l-треонина и способ получения l-треонина |
RU2004103986 | 2004-02-12 | ||
US60114404P | 2004-08-13 | 2004-08-13 | |
US60/601,144 | 2004-08-13 | ||
PCT/JP2005/002372 WO2005078113A1 (en) | 2004-02-12 | 2005-02-09 | Method for producing l-threonine using bacteria belonging to the genus escherichia |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0507647A true BRPI0507647A (pt) | 2007-07-10 |
BRPI0507647B1 BRPI0507647B1 (pt) | 2020-12-08 |
Family
ID=34863655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0507647-1A BRPI0507647B1 (pt) | 2004-02-12 | 2005-02-09 | método para produzir l-treonina |
Country Status (4)
Country | Link |
---|---|
US (1) | US20050181488A1 (pt) |
EP (1) | EP1720993B8 (pt) |
BR (1) | BRPI0507647B1 (pt) |
WO (1) | WO2005078113A1 (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2229513C2 (ru) * | 2001-11-23 | 2004-05-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислот, штамм escherichia coli - продуцент l-аминокислоты (варианты) |
RU2273666C2 (ru) * | 2003-02-26 | 2006-04-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислот методом ферментации смеси глюкозы и пентоз |
US7915018B2 (en) * | 2004-10-22 | 2011-03-29 | Ajinomoto Co., Inc. | Method for producing L-amino acids using bacteria of the Enterobacteriaceae family |
RU2338784C2 (ru) * | 2006-03-24 | 2008-11-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Новая альдолаза, днк, кодирующая альдолазу, клетки, трансформированные днк, способ получения альдолазы и способ получения 4-гидрокси-l-изолейцина (варианты) |
RU2006129690A (ru) | 2006-08-16 | 2008-02-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ |
EP2066799B1 (en) | 2006-09-28 | 2013-12-11 | Ajinomoto Co., Inc. | Method for producing 4-hydroxy-l-isoleucine |
KR100869625B1 (ko) * | 2007-04-11 | 2008-11-21 | 씨제이제일제당 (주) | L-쓰레오닌 생산 미생물 및 이를 이용한 l-쓰레오닌의생산 방법 |
JP2010263790A (ja) * | 2007-09-04 | 2010-11-25 | Ajinomoto Co Inc | アミノ酸生産微生物及びアミノ酸の製造法 |
RU2395579C2 (ru) * | 2007-12-21 | 2010-07-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia |
EP2201126A4 (en) * | 2007-09-26 | 2012-05-09 | Archer Daniels Midland Co | PRODUCTION OF AMINO ACIDS FROM SUCROSE IN <I> CORYNEBACTERIUM GLUTAMICUM </ I> |
RU2395580C2 (ru) * | 2007-12-21 | 2010-07-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Способ конструирования бактерии-продуцента (2s,3r,4s)-4-гидрокси-l-изолейцина, бактерия-продуцент (2s,3r,4s)-4-гидрокси-l-изолейцина и способ продукции (2s,3r,4s)-гидрокси-l-изолейцина или его соли |
RU2007147436A (ru) * | 2007-12-21 | 2009-06-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Бактерия-продуцент (2s,3r,4s)-4-гидрокси-l-изолейцина и способ продукции (2s,3r,4s)-4-гидрокси-l-изолейцина |
RU2008105793A (ru) * | 2008-02-19 | 2009-08-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Способ конструирования оперонов, содержащих трансляционно сопряженные гены, бактерия, содержащая такой оперон, способ продукции полезного метаболита и способ мониторинга экспрессии гена |
US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
JP2010142200A (ja) | 2008-12-22 | 2010-07-01 | Ajinomoto Co Inc | L−リジンの製造法 |
CN102666838B (zh) | 2009-11-18 | 2018-04-10 | 麦兰特公司 | 用于高效产生化学品的工程化微生物 |
AU2010321223A1 (en) * | 2009-11-18 | 2012-08-02 | Basf Plant Science Company Gmbh | Process for the production of fine chemicals |
JP2017192325A (ja) * | 2016-04-19 | 2017-10-26 | 三菱ケミカル株式会社 | 有機酸の製造方法 |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU875663A1 (ru) * | 1978-06-30 | 1982-09-15 | Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Штаммы е.coLI ВНИИГенетика VL 334 @ N6 и ВНИИГенетика VL 334 @ N7-продуценты L-треонина и способ их получени |
JPS5618596A (en) * | 1979-07-23 | 1981-02-21 | Ajinomoto Co Inc | Production of l-lysine through fermentation process |
WO1990004636A1 (en) * | 1988-10-25 | 1990-05-03 | Vsesojuzny Nauchno-Issledovatelsky Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov (Vniigenetika) | Strain of bacteria escherichia coli, producer of l-threonine |
US5705371A (en) * | 1990-06-12 | 1998-01-06 | Ajinomoto Co., Inc. | Bacterial strain of escherichia coli BKIIM B-3996 as the producer of L-threonine |
US5976843A (en) * | 1992-04-22 | 1999-11-02 | Ajinomoto Co., Inc. | Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine |
JP3006926B2 (ja) * | 1991-09-04 | 2000-02-07 | 協和醗酵工業株式会社 | 発酵法によるl−スレオニンの製造法 |
ATE203769T1 (de) * | 1992-11-10 | 2001-08-15 | Ajinomoto Kk | Dna, die aspartokinase iii-mutanten kodiert und ihre verwendung zur herstellung von l-threonin durch fermentation |
JPH07155184A (ja) * | 1993-12-08 | 1995-06-20 | Ajinomoto Co Inc | 発酵法によるl−リジンの製造法 |
US5939307A (en) * | 1996-07-30 | 1999-08-17 | The Archer-Daniels-Midland Company | Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production |
DE19644566A1 (de) * | 1996-10-26 | 1998-04-30 | Forschungszentrum Juelich Gmbh | Mikrobielle Herstellung von Substanzen aus dem aromatischen Stoffwechsel / I |
US6586214B1 (en) * | 1999-09-15 | 2003-07-01 | Degussa Ag | Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene) |
US7220571B2 (en) * | 2000-09-28 | 2007-05-22 | Archer-Daniels-Midland Company | Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation |
DE60225288T2 (de) * | 2001-07-18 | 2009-03-26 | Evonik Degussa Gmbh | Verfahren zur herstellung von l-aminosäuren unter verwendung von stämmen aus der familie der enterobacteriaceae die ein attenuiertes ugpb-gen enthalten |
DE10135053A1 (de) * | 2001-07-18 | 2003-02-06 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
CN1615359B (zh) * | 2001-11-23 | 2010-04-28 | 味之素株式会社 | 利用埃希杆菌属细菌生产l-氨基酸的方法 |
RU2229513C2 (ru) * | 2001-11-23 | 2004-05-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислот, штамм escherichia coli - продуцент l-аминокислоты (варианты) |
RU2244007C2 (ru) * | 2002-02-27 | 2005-01-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-треонина, штамм escherichia coli - продуцент треонина (варианты) |
US20040038372A1 (en) * | 2002-05-08 | 2004-02-26 | Degussa Ag | Process for the production of amino acids with coryneform bacteria using phosphoglucose isomerases from coryneform bacteria |
DE10316109A1 (de) * | 2003-04-09 | 2004-10-21 | Degussa Ag | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
RU2276686C2 (ru) * | 2003-08-29 | 2006-05-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Бактерия, принадлежащая к роду escherichia, - продуцент l-аргинина и способ получения l-аргинина |
-
2005
- 2005-02-08 US US11/052,140 patent/US20050181488A1/en not_active Abandoned
- 2005-02-09 EP EP05710272.5A patent/EP1720993B8/en active Active
- 2005-02-09 WO PCT/JP2005/002372 patent/WO2005078113A1/en active Application Filing
- 2005-02-09 BR BRPI0507647-1A patent/BRPI0507647B1/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP1720993B8 (en) | 2014-02-19 |
WO2005078113A1 (en) | 2005-08-25 |
EP1720993A1 (en) | 2006-11-15 |
BRPI0507647B1 (pt) | 2020-12-08 |
EP1720993B1 (en) | 2013-10-16 |
US20050181488A1 (en) | 2005-08-18 |
WO2005078113B1 (en) | 2005-11-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/12/2020, OBSERVADAS AS CONDICOES LEGAIS. |