BRPI0507222A - composto, composição cosmética, método cosmético de clareamento da pele, uso de composto e processo de fabricação de composto - Google Patents

composto, composição cosmética, método cosmético de clareamento da pele, uso de composto e processo de fabricação de composto

Info

Publication number
BRPI0507222A
BRPI0507222A BRPI0507222-0A BRPI0507222A BRPI0507222A BR PI0507222 A BRPI0507222 A BR PI0507222A BR PI0507222 A BRPI0507222 A BR PI0507222A BR PI0507222 A BRPI0507222 A BR PI0507222A
Authority
BR
Brazil
Prior art keywords
cycloalkyl
saturated
cosmetic
skin
branched
Prior art date
Application number
BRPI0507222-0A
Other languages
English (en)
Inventor
Bijan Harichian
Jose Guillermo Rosa
Michael James Barratt
Carol Annette Bosko
John Steven Bajor
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Nv filed Critical Unilever Nv
Publication of BRPI0507222A publication Critical patent/BRPI0507222A/pt
Publication of BRPI0507222B1 publication Critical patent/BRPI0507222B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

COMPOSTO, COMPOSIçãO COSMéTICA, MéTODO COSMéTICO DE CLAREAMENTO DA PELE, USO DE COMPOSTO E PROCESSO DE FABRICAçãO DE COMPOSTO. A presente invenção fornece compostos derivados de coumarina da fórmula (I) como agentes clareadores da pele isoladamente ou em combinação com outros agentes benéficos para a pele e junto com veículo cosmético: fórmula (I), em que R~1 e/ou R~2 ambos ou isoladamente, representam hidrogênio (H); grupos alquila, alquenila, acila ou heteroalquila (preferencialmente alcóxi) C~1-C~12 lineares ou ramificados, saturados ou insaturados; R~3 representa grupo alquila, alquenila, cicloalquila, cicloalquila, cicloalquenila ou heteroalquila C~1 C~12 linear ou ramificado, cíclico ou acíclico, saturado ou insaturado; R~5 representa um átomo de hidrogênio (H) ou R~4; e R~4 representa grupo alquila, alquenila, cicloalquila, cicloalquenila, heteroalquila, arila ou heteroarila C~1-C~22 linear ou ramificado, cíclico ou acíclico, saturado ou insaturado, que contém ou não contém um heteroátomo. Os compostos, composições e métodos possuem propriedades efetivas de clareamento da pele, podem ser menos irritantes para a pele e são eficazes para o seu custo e de fabricação relativamente simples. Também são fornecidos processos de fabricação dos compostos da fórmula geral (I) a partir de derivados de 7-hidróxicoumarina 4-substituidos.
BRPI0507222A 2004-02-27 2005-02-16 composto, composição cosmética, método cosmético de clareamento da pele, uso de composto e processo de fabricação de composto BRPI0507222B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/789,293 2004-02-27
US10/789,293 US7300646B2 (en) 2004-02-27 2004-02-27 Skin lightening agents, compositions and methods
PCT/EP2005/001595 WO2005085169A1 (en) 2004-02-27 2005-02-16 Skin lightening agents, compositions and methods

Publications (2)

Publication Number Publication Date
BRPI0507222A true BRPI0507222A (pt) 2007-06-19
BRPI0507222B1 BRPI0507222B1 (pt) 2015-09-08

Family

ID=34887242

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507222A BRPI0507222B1 (pt) 2004-02-27 2005-02-16 composto, composição cosmética, método cosmético de clareamento da pele, uso de composto e processo de fabricação de composto

Country Status (10)

Country Link
US (2) US7300646B2 (pt)
EP (1) EP1718594B1 (pt)
JP (1) JP4855382B2 (pt)
AU (1) AU2005219510B2 (pt)
BR (1) BRPI0507222B1 (pt)
ES (1) ES2543980T3 (pt)
NZ (1) NZ549358A (pt)
TW (1) TWI391145B (pt)
WO (1) WO2005085169A1 (pt)
ZA (1) ZA200607017B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7300646B2 (en) * 2004-02-27 2007-11-27 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Skin lightening agents, compositions and methods
US7365125B2 (en) * 2004-08-16 2008-04-29 General Electric Company Polycarbonate compositions, articles, and method of manufacture
US20090263513A1 (en) * 2008-04-18 2009-10-22 Jan Marini Cosmetic skin lightening formulation
FR2939135B1 (fr) 2008-12-02 2010-12-03 Galderma Res & Dev Nouveaux composes 4-(azacycloalkyl)-benzene-1,3-diol comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
FR2939136B1 (fr) 2008-12-02 2010-12-03 Galderma Res & Dev Nouveaux composes 4-(heterocycloalkyl)-benzene-1,3-diol comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
US9044623B2 (en) * 2009-01-27 2015-06-02 Isp Investments Inc. Polymer-bound UV absorbers in personal care compositions
US20120245205A1 (en) 2009-07-29 2012-09-27 Delong Mitchell A Compositions and methods for inhibiting hair growth
FR2953834B1 (fr) 2009-12-10 2012-01-13 Galderma Res & Dev Nouveaux composes 4-(azacycloalkyl)-benzene-1,3-diol comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
EP2516669B1 (en) 2009-12-21 2016-10-12 Advanced Liquid Logic, Inc. Enzyme assays on a droplet actuator
US9513253B2 (en) 2011-07-11 2016-12-06 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based enzymatic assays
KR101457370B1 (ko) * 2012-09-06 2014-11-03 (주)에이씨티 신규 벤젠 디올 유도체 화합물 및 이를 이용한 화장료 조성물
CA3167320A1 (en) 2013-03-08 2014-09-12 Unilever Global Ip Limited Resorcinol compounds for dermatological use
WO2017025105A1 (en) * 2015-08-12 2017-02-16 Nmetics Ivs 3-(4-hydroxyphenyl)propanoic acid amide for use in tissue repair and/or skin brightening
FR3045039B1 (fr) * 2015-12-15 2017-12-22 Oreal Derives de resorcinol pour leur utilisation cosmetique
FR3045600B1 (fr) * 2015-12-16 2018-01-26 L'oreal Derives de resorcinol pour leur utilisation cosmetique
FR3067027B1 (fr) * 2017-05-31 2019-06-21 L'oreal Derives de resorcinol pour leur utilisation cosmetique

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1581428A (en) 1978-03-13 1980-12-10 Conoco Inc Alkylation of aromatic hydroxy compounds
EP0071570A1 (en) * 1981-06-19 1983-02-09 Ciba-Geigy Ag Process for the production of a photographic black dye image
JPH0651619B2 (ja) * 1988-05-09 1994-07-06 株式会社クラレ 美白剤
FR2704428B1 (fr) * 1993-04-29 1995-06-09 Oreal Utilisation de dérivés de la résorcine substitués en position(s) 4, 4 et 5 ou 4 et 6 dans des compositions cosmétiques ou dermopharmaceutiques à action dépigmentante.
JPH10316641A (ja) * 1997-03-14 1998-12-02 Sankyo Co Ltd カルボン酸誘導体
BR9803596A (pt) * 1997-09-23 2000-04-25 Pfizer Prod Inc Derivados do resorcinol.
JP4004182B2 (ja) 1999-05-24 2007-11-07 ポーラ化成工業株式会社 乳化組成物
JP4015781B2 (ja) 1999-06-28 2007-11-28 ポーラ化成工業株式会社 乳化組成物
EP1134207A1 (en) 2000-03-15 2001-09-19 Pfizer Products Inc. Process for preparing resorcinol derivatives
US6852310B2 (en) 2002-08-23 2005-02-08 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Skin lightening agents, compositions and methods
US7300646B2 (en) 2004-02-27 2007-11-27 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Skin lightening agents, compositions and methods

Also Published As

Publication number Publication date
US7723537B2 (en) 2010-05-25
ZA200607017B (en) 2008-04-30
US20080039636A1 (en) 2008-02-14
US7300646B2 (en) 2007-11-27
AU2005219510B2 (en) 2008-05-15
ES2543980T3 (es) 2015-08-26
TW200531706A (en) 2005-10-01
EP1718594B1 (en) 2015-06-10
WO2005085169A1 (en) 2005-09-15
BRPI0507222B1 (pt) 2015-09-08
US20050191250A1 (en) 2005-09-01
TWI391145B (zh) 2013-04-01
JP4855382B2 (ja) 2012-01-18
JP2007523932A (ja) 2007-08-23
EP1718594A1 (en) 2006-11-08
NZ549358A (en) 2010-01-29
AU2005219510A1 (en) 2005-09-15

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C07C 59/52 , C07C 69/732

Ipc: A61K 8/365 (2006.01), A61K 8/37 (2006.01), A61Q 19

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/09/2015, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REFERENTE A RPI 2331 DE 08/09/2015, QUANTO AO TITULO DA PATENTE.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2501 DE 11-12-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.