BRPI0505586A - material substituto do osso contendo antibiótico/antibióticos com liberação de substáncia ativa de ação retardadora - Google Patents
material substituto do osso contendo antibiótico/antibióticos com liberação de substáncia ativa de ação retardadoraInfo
- Publication number
- BRPI0505586A BRPI0505586A BRPI0505586-5A BRPI0505586A BRPI0505586A BR PI0505586 A BRPI0505586 A BR PI0505586A BR PI0505586 A BRPI0505586 A BR PI0505586A BR PI0505586 A BRPI0505586 A BR PI0505586A
- Authority
- BR
- Brazil
- Prior art keywords
- antibiotics
- antibiotic
- bone substitute
- active substance
- glycerine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"MATERIAL SUBSTITUTO DO OSSO CONTENDO ANTIBIóTICO/ANTIBIóTICOS COM LIBERAçãO DE SUBSTáNCIA ATIVA DE AçãO RETARDADORA". A presente invenção refere-se a um material substituto do osso contendo antibiótico/antibióticos, caracterizado pelo fato de ser formado de uma mistura condensada de grânulos do dihidrato de sulfato de cálcio, do carbonato de cálcio e de pelo menos um representante dos antibióticos aminoglicosídeo, dos antibióticos lincosamida, dos antibióticos glicopeptídeo, dos antibióticos macrolida, dos antíbióticos cetolida, dos nitroimidazóis, dos antibióticos fluorquinoiona e dos antibióticos oxazolidinona, dos antibióticos esteroidais, dos anti-sépticos e dos antibióticos fungicidas/fungistáticos, que são parcialmente ou completamente envolvidos com uma camada de tripalmitato de glicerina e/ou triestearato de glicerina e/ou trilaurato de glicerina e/ou álcool l-hexadecílico, a qual liga os grânulos uns com os outros.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004060666A DE102004060666B3 (de) | 2004-12-15 | 2004-12-15 | Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0505586A true BRPI0505586A (pt) | 2006-09-12 |
BRPI0505586B1 BRPI0505586B1 (pt) | 2018-05-08 |
Family
ID=36011910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0505586A BRPI0505586B1 (pt) | 2004-12-15 | 2005-12-14 | material substituto do osso contendo antibiótico, com liberação sustentada do dito antibiótico |
Country Status (15)
Country | Link |
---|---|
US (1) | US7923019B2 (pt) |
EP (1) | EP1671661B1 (pt) |
JP (1) | JP4523544B2 (pt) |
CN (1) | CN100571792C (pt) |
AU (1) | AU2005239648B2 (pt) |
BR (1) | BRPI0505586B1 (pt) |
CA (1) | CA2526954C (pt) |
CY (1) | CY1110514T1 (pt) |
DE (2) | DE102004060666B3 (pt) |
DK (1) | DK1671661T3 (pt) |
ES (1) | ES2330015T3 (pt) |
PL (1) | PL1671661T3 (pt) |
PT (1) | PT1671661E (pt) |
SI (1) | SI1671661T1 (pt) |
ZA (1) | ZA200510166B (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006016598A1 (de) * | 2006-04-06 | 2007-11-15 | Heraeus Kulzer Gmbh | Beschichtete Vaskulärimplantate |
DE102006037362B3 (de) * | 2006-08-09 | 2007-09-20 | Heraeus Kulzer Gmbh | Knochenersatzmaterial |
JP2010527252A (ja) * | 2007-05-10 | 2010-08-12 | スミス アンド ネフュー インコーポレーテッド | カルシウムセンシング受容体の増強 |
EP2018864A1 (en) | 2007-07-23 | 2009-01-28 | Biomet Deutschland GmbH | Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition |
US8226766B2 (en) * | 2010-12-22 | 2012-07-24 | United States Gypsum Company | Set accelerator for gypsum hydration |
DE102011016277B4 (de) * | 2011-04-06 | 2013-02-21 | Heraeus Medical Gmbh | Plastisch verformbares, biodegradierbares Hämostyptikum und Verfahren zum Formen eines solchen |
DE102011122752B3 (de) * | 2011-04-06 | 2013-02-21 | Heraeus Medical Gmbh | Medizinisches Implantat enthaltend ein plastisch verformbares,biodegradierbares Hämostyptikum |
ES2393602B1 (es) | 2011-06-09 | 2013-10-02 | Universidad Complutense De Madrid | Materiales biocerámicos para el tratamiento de la osteomielitis. |
DE102012014419A1 (de) * | 2012-07-20 | 2014-01-23 | Heraeus Medical Gmbh | Pastenförmiges Knochenersatzmaterial |
CN103143024B (zh) * | 2013-02-22 | 2014-06-25 | 浙江省中医药研究院 | 一种植入型补肾健骨中药提取物-抗生素-硫酸钙缓释系统及其制备方法和应用 |
CN103446622B (zh) * | 2013-08-13 | 2015-07-08 | 江苏大学 | 一种利用α-半水硫酸钙晶须释放钙及万古霉素的方法 |
DE102015100806A1 (de) * | 2015-01-20 | 2016-07-21 | Antonis Alexakis | Biokompatibles Formteil |
EP4382109A1 (de) * | 2022-12-06 | 2024-06-12 | Heraeus Medical GmbH | Anwendung eines kompositmaterials |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2672070A (en) | 1953-06-10 | 1954-03-16 | Heli Coil Corp | Wire coil screw thread insert for molded material |
DE1027914B (de) | 1953-08-22 | 1958-04-10 | Draegerwerk Ag | Reifendruckmessgeraet |
DE1027935B (de) | 1955-09-08 | 1958-04-10 | Porsche Kg | Luftgekuehlte Brennkraftmaschine, insbesondere fuer den Antrieb von Kraftfahrzeugen |
EP0376331A3 (en) * | 1988-12-29 | 1991-03-13 | Asahi Kogaku Kogyo Kabushiki Kaisha | Slow release drug delivery granules and process for production thereof |
US5149368A (en) * | 1991-01-10 | 1992-09-22 | Liu Sung Tsuen | Resorbable bioactive calcium phosphate cement |
US5681873A (en) | 1993-10-14 | 1997-10-28 | Atrix Laboratories, Inc. | Biodegradable polymeric composition |
US5614206A (en) | 1995-03-07 | 1997-03-25 | Wright Medical Technology, Inc. | Controlled dissolution pellet containing calcium sulfate |
US5756127A (en) | 1996-10-29 | 1998-05-26 | Wright Medical Technology, Inc. | Implantable bioresorbable string of calcium sulfate beads |
EP0985413A1 (de) * | 1998-08-06 | 2000-03-15 | Jörg Michael Dr. Dr. Schierholz | Medizinprodukte mit retardierter pharmakologischer Aktivität und Verfahren zu ihrer Herstellung |
US6224635B1 (en) * | 1998-11-06 | 2001-05-01 | Hospital For Joint Diseases | Implantation of surgical implants with calcium sulfate |
CA2360938C (en) | 1999-02-02 | 2008-01-08 | Warren Oliver Haggard | Controlled release composite |
US7371408B1 (en) | 1999-06-07 | 2008-05-13 | Wright Medical Technology, Inc. | Bone graft substitute composition |
DE19953771C1 (de) | 1999-11-09 | 2001-06-13 | Coripharm Medizinprodukte Gmbh | Resorbierbares Knochen-Implantatmaterial sowie Verfahren zur Herstellung desselben |
SE520688C2 (sv) | 2000-04-11 | 2003-08-12 | Bone Support Ab | Ett injicerbart ersättningsmaterial för benmineral |
EP1153621A1 (de) * | 2000-05-12 | 2001-11-14 | MERCK PATENT GmbH | Biozemente auf TCP-PHA-Basismischung mit verbesserter Kompressionsfestigkeit |
DE10114245A1 (de) | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
DE10114364A1 (de) | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Verfahren zur Herstellung von antibiotischen Kompositen |
DE10114244A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung |
RU2005101077A (ru) * | 2002-06-19 | 2005-07-10 | Др. Х.К. Роберт Матис Стифтунг (Ch) | Гидравлический цемент на основе фосфата кальция для применения в хирургии |
DE10227914A1 (de) * | 2002-06-21 | 2004-01-15 | Heraeus Kulzer Gmbh & Co. Kg | Pharmazeutische Zubereitung mit retardierender Wirkstofffreisetzung, Verfahren zu ihrer Herstellung und Verwendung |
DE10227938B4 (de) | 2002-06-21 | 2006-07-20 | Heraeus Kulzer Gmbh | Pharmazeutische Zubereitung, Verfahren zu ihrer Herstellung sowie deren Verwendung |
DE10262176B4 (de) * | 2002-06-21 | 2007-10-04 | Heraeus Kulzer Gmbh | Verfahren zur Herstellung von antibiotisch beschichteten porösen Körpern sowie Verwendung |
US6652887B1 (en) | 2002-06-24 | 2003-11-25 | Wright Medical Technology, Inc. | Bone graft substitute composition |
US8029755B2 (en) * | 2003-08-06 | 2011-10-04 | Angstrom Medica | Tricalcium phosphates, their composites, implants incorporating them, and method for their production |
-
2004
- 2004-12-15 DE DE102004060666A patent/DE102004060666B3/de active Active
-
2005
- 2005-11-14 CA CA002526954A patent/CA2526954C/en not_active Expired - Fee Related
- 2005-11-24 PT PT05025607T patent/PT1671661E/pt unknown
- 2005-11-24 PL PL05025607T patent/PL1671661T3/pl unknown
- 2005-11-24 DE DE502005007699T patent/DE502005007699D1/de active Active
- 2005-11-24 DK DK05025607T patent/DK1671661T3/da active
- 2005-11-24 EP EP05025607A patent/EP1671661B1/de active Active
- 2005-11-24 ES ES05025607T patent/ES2330015T3/es active Active
- 2005-11-24 SI SI200530801T patent/SI1671661T1/sl unknown
- 2005-11-29 AU AU2005239648A patent/AU2005239648B2/en active Active
- 2005-12-05 US US11/294,001 patent/US7923019B2/en active Active
- 2005-12-07 CN CNB2005101310932A patent/CN100571792C/zh active Active
- 2005-12-14 ZA ZA200510166A patent/ZA200510166B/xx unknown
- 2005-12-14 BR BRPI0505586A patent/BRPI0505586B1/pt not_active IP Right Cessation
- 2005-12-15 JP JP2005362356A patent/JP4523544B2/ja active Active
-
2009
- 2009-10-15 CY CY20091101077T patent/CY1110514T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
US20060127444A1 (en) | 2006-06-15 |
JP4523544B2 (ja) | 2010-08-11 |
DE102004060666B3 (de) | 2006-03-30 |
ZA200510166B (en) | 2006-11-29 |
PT1671661E (pt) | 2009-10-22 |
CA2526954C (en) | 2009-06-02 |
EP1671661A2 (de) | 2006-06-21 |
CY1110514T1 (el) | 2015-04-29 |
AU2005239648B2 (en) | 2007-08-16 |
EP1671661A3 (de) | 2007-10-03 |
PL1671661T3 (pl) | 2010-01-29 |
EP1671661B1 (de) | 2009-07-15 |
CA2526954A1 (en) | 2006-06-15 |
SI1671661T1 (sl) | 2010-01-29 |
US7923019B2 (en) | 2011-04-12 |
DK1671661T3 (da) | 2009-11-16 |
BRPI0505586B1 (pt) | 2018-05-08 |
CN100571792C (zh) | 2009-12-23 |
CN1795934A (zh) | 2006-07-05 |
DE502005007699D1 (de) | 2009-08-27 |
ES2330015T3 (es) | 2009-12-03 |
JP2006167469A (ja) | 2006-06-29 |
AU2005239648A1 (en) | 2006-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: HERAEUS MEDICAL GMBH (DE) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 15A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2609 DE 05-01-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |