BRPI0415363A - molécula de ácido nucleico isolada a partir de nicotina, planta transgênica, e, métodos de produção de uma planta transgênica, de seleção de uma planta contendo uma molécula de ácido nucleico, e de aumento ou diminuição dos nìveis de nornicotina em uma planta - Google Patents
molécula de ácido nucleico isolada a partir de nicotina, planta transgênica, e, métodos de produção de uma planta transgênica, de seleção de uma planta contendo uma molécula de ácido nucleico, e de aumento ou diminuição dos nìveis de nornicotina em uma plantaInfo
- Publication number
- BRPI0415363A BRPI0415363A BRPI0415363-4A BRPI0415363A BRPI0415363A BR PI0415363 A BRPI0415363 A BR PI0415363A BR PI0415363 A BRPI0415363 A BR PI0415363A BR PI0415363 A BRPI0415363 A BR PI0415363A
- Authority
- BR
- Brazil
- Prior art keywords
- plant
- nucleic acid
- acid molecule
- transgenic plant
- methods
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title 2
- 108020004707 nucleic acids Proteins 0.000 title 2
- 230000009261 transgenic effect Effects 0.000 title 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title 1
- MYKUKUCHPMASKF-VIFPVBQESA-N (S)-nornicotine Chemical compound C1CCN[C@@H]1C1=CC=CN=C1 MYKUKUCHPMASKF-VIFPVBQESA-N 0.000 title 1
- MYKUKUCHPMASKF-UHFFFAOYSA-N Nornicotine Natural products C1CCNC1C1=CC=CN=C1 MYKUKUCHPMASKF-UHFFFAOYSA-N 0.000 title 1
- 230000003247 decreasing effect Effects 0.000 title 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title 1
- 229960002715 nicotine Drugs 0.000 title 1
- 102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 abstract 2
- 108010015742 Cytochrome P-450 Enzyme System Proteins 0.000 abstract 2
- 241000196324 Embryophyta Species 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 241000208125 Nicotiana Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/686,947 US20040162420A1 (en) | 2002-10-16 | 2003-10-16 | Cloning of cytochrome p450 genes from nicotiana |
| US56623504P | 2004-04-29 | 2004-04-29 | |
| US10/934,944 US7812227B2 (en) | 2001-11-13 | 2004-09-03 | Cloning of cytochrome p450 genes from nicotiana |
| PCT/US2004/034065 WO2005038033A2 (en) | 2003-10-16 | 2004-10-15 | Cloning of cytochrome p450 genes from nicotiana |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0415363A true BRPI0415363A (pt) | 2006-12-12 |
Family
ID=34468385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0415363-4A BRPI0415363A (pt) | 2003-10-16 | 2004-10-15 | molécula de ácido nucleico isolada a partir de nicotina, planta transgênica, e, métodos de produção de uma planta transgênica, de seleção de uma planta contendo uma molécula de ácido nucleico, e de aumento ou diminuição dos nìveis de nornicotina em uma planta |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1675957B1 (enExample) |
| JP (2) | JP5422099B2 (enExample) |
| CN (1) | CN102321641A (enExample) |
| AT (1) | ATE536415T1 (enExample) |
| AU (3) | AU2004282576B2 (enExample) |
| BR (1) | BRPI0415363A (enExample) |
| ES (1) | ES2377868T3 (enExample) |
| PL (1) | PL1675957T3 (enExample) |
| WO (1) | WO2005038033A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10266836B2 (en) | 2001-11-13 | 2019-04-23 | U.S. Smokeless Tobacco Company Llc | Tobacco nicotine demethylase genomic clone and uses thereof |
| US7812227B2 (en) | 2001-11-13 | 2010-10-12 | U.S. Smokeless Tobacco Company | Cloning of cytochrome p450 genes from nicotiana |
| US8592663B2 (en) | 2001-11-13 | 2013-11-26 | U.S. Smokeless Tobacco Company Llc | Tobacco nicotine demethylase genomic clone and uses thereof |
| US7700851B2 (en) | 2001-11-13 | 2010-04-20 | U.S. Smokeless Tobacco Company | Tobacco nicotine demethylase genomic clone and uses thereof |
| US7700834B2 (en) | 2001-11-13 | 2010-04-20 | U.S. Smokless Tobacco Company | Nicotiana nucleic acid molecules and uses thereof |
| EP2330191A1 (en) | 2003-10-16 | 2011-06-08 | U.S. Smokeless Tobacco Company | Cloning of cytochrome P450 genes from nicotiana |
| JP4519137B2 (ja) * | 2003-10-16 | 2010-08-04 | ユーエス スモークレス タバコ カンパニー | タバコ属(Nicotiana)からのチトクロムp450遺伝子のクローニング |
| US8586837B2 (en) | 2004-04-29 | 2013-11-19 | U.S. Smokeless Tobacco Company Llc | Nicotiana nucleic acid molecules and uses thereof |
| EP1851317B1 (en) | 2005-02-23 | 2011-10-26 | North Carolina State University | Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes |
| US8319011B2 (en) | 2006-12-15 | 2012-11-27 | U.S. Smokeless Tobacco Company Llc | Tobacco plants having reduced nicotine demethylase activity |
| US11332753B2 (en) | 2006-12-15 | 2022-05-17 | U.S. Smokeless Tobacco Company Llc | Tobacco plants having reduced nicotine demethylase activity |
| BRPI0820042B1 (pt) | 2007-11-12 | 2020-05-19 | North Carolina State University | método de obtenção de uma planta de tabaco, ou célula ou parte desta, tendo níveis reduzidos de nornicotina, produto de tabaco, método para fabricar um produto de tabaco, polinucleotídeo isolado, cassete de expressão, polipetpídeo isolado e método de obtenção de uma planta, ou parte de planta desta, do gênero nicotiana |
| PH12012501393B1 (en) | 2010-01-15 | 2017-10-25 | Univ North Carolina State | Compositions and methods for minimizing nornicotine synthesis in tobacco |
| KR20140034160A (ko) | 2011-02-28 | 2014-03-19 | 알트리아 클라이언트 서비시스 인코포레이티드 | 담배 근친교배 식물체 albex1f 및 albex1ms |
| BR112013021515A2 (pt) | 2011-02-28 | 2018-06-12 | Univ North Carolina State | plantas congênitas de tabaco ncbex1f, ncbex1ms e nc ex90 |
| CN103361368B (zh) * | 2012-03-27 | 2015-03-04 | 华中农业大学 | 一种棉花细胞色素p450基因及应用 |
| CN102796821A (zh) * | 2012-08-30 | 2012-11-28 | 浙江中烟工业有限责任公司 | 一种检测烟草烟碱转化相对水平的方法 |
| WO2014110363A1 (en) | 2013-01-11 | 2014-07-17 | North Carolina State University | Tobacco inbred plants k326 src, cms k326 src, k346 src, cms k346 src, nc1562-1 src, nctg-61 src, cms nctg-61 src and hybrid nc196 src |
| EP2964016A1 (en) | 2013-03-05 | 2016-01-13 | North Carolina State University | Tobacco inbred and hybrid plants and uses thereof |
| WO2015051454A1 (en) * | 2013-10-07 | 2015-04-16 | Vineland Research And Innovation Centre | Compositions and methods for producing steviol and steviol glycosides |
| CN106659232A (zh) | 2014-03-03 | 2017-05-10 | 北卡罗莱纳州立大学 | 烟草近交和杂种植物以及由其制得的烟草产品 |
| EP3113603A1 (en) | 2014-03-03 | 2017-01-11 | North Carolina State University | Tobacco inbred and hybrid plants and tobacco products made thereof |
| EP3113602A1 (en) | 2014-03-03 | 2017-01-11 | North Carolina State University | Tobacco inbred and hybrid plants and tobacco products made thereof |
| CN110305893B (zh) * | 2018-03-23 | 2022-09-06 | 中国科学院分子植物科学卓越创新中心 | 棉酚生物合成途径基因cyp71be79及其应用 |
| CN111849931A (zh) * | 2019-04-26 | 2020-10-30 | 西南大学 | 川桑色氨酸羟化酶t5h2及其应用 |
| CN110923249A (zh) * | 2019-10-15 | 2020-03-27 | 贵州省烟草科学研究院 | 烟草CyP71及在调控植物表皮毛发育方面的应用 |
| US20240218386A1 (en) * | 2019-12-03 | 2024-07-04 | Altria Client Services Llc | Compositions and Methods for Producing Tobacco Plants and Products Having Altered Alkaloid Levels |
| CN110885841B (zh) * | 2019-12-24 | 2022-04-12 | 河南科技大学 | 葡萄VyCYP89A2基因及其编码蛋白和基因在抗旱品种育种中的应用 |
| CN113234739B (zh) * | 2021-05-26 | 2023-12-26 | 云南中烟工业有限责任公司 | 烟草细胞色素p450亚家族cyp710a基因及应用 |
| CN118272399A (zh) * | 2024-04-19 | 2024-07-02 | 华中农业大学 | 一种应用OfCYP244基因提高桂花花瓣香气物质芳樟醇的方法 |
| CN118773150B (zh) * | 2024-06-03 | 2025-06-17 | 上海大学 | 一种银胶菊素c2羟化酶及其编码基因、制备方法与应用 |
| CN119876057B (zh) * | 2025-01-16 | 2025-09-23 | 南京师范大学 | Cyp71p2酶、生物材料及应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1152029A (zh) * | 1995-12-11 | 1997-06-18 | 浙江医科大学 | 人细胞色素p450系列转基因细胞株 |
| CN1341631A (zh) * | 2000-09-05 | 2002-03-27 | 上海博德基因开发有限公司 | 一种新的多肽——人细胞色素P450Cys亚铁血红素-铁蛋白9.13和编码这种多肽的多核苷酸 |
| AU2002244262B2 (en) * | 2001-03-09 | 2007-07-12 | University Of Kentucky Research Foundation | Cytochrome P450s and uses thereof |
| CN1382707A (zh) * | 2001-04-26 | 2002-12-04 | 上海博德基因开发有限公司 | 一种多肽——细胞色素p-450p-2-48.84和编码这种多肽的多核苷酸 |
| KR20040091124A (ko) * | 2002-03-12 | 2004-10-27 | 유.에스.스모크리스 토바코 컴퍼니 | 니코티아나 사이토크롬 p450 유전자의 클로닝 |
| EP2336305A3 (en) * | 2002-10-16 | 2011-10-05 | U.S. Smokeless Tobacco Company LLC | Cloning of cytochrome P450 genes from Nicotiana |
-
2004
- 2004-10-15 CN CN2011102770337A patent/CN102321641A/zh active Pending
- 2004-10-15 AT AT04795252T patent/ATE536415T1/de active
- 2004-10-15 BR BRPI0415363-4A patent/BRPI0415363A/pt not_active Application Discontinuation
- 2004-10-15 ES ES04795252T patent/ES2377868T3/es not_active Expired - Lifetime
- 2004-10-15 EP EP04795252A patent/EP1675957B1/en not_active Expired - Lifetime
- 2004-10-15 JP JP2006535343A patent/JP5422099B2/ja not_active Expired - Lifetime
- 2004-10-15 WO PCT/US2004/034065 patent/WO2005038033A2/en not_active Ceased
- 2004-10-15 PL PL04795252T patent/PL1675957T3/pl unknown
- 2004-10-15 AU AU2004282576A patent/AU2004282576B2/en not_active Expired
-
2010
- 2010-04-28 AU AU2010201695A patent/AU2010201695B2/en not_active Expired
- 2010-04-28 AU AU2010201696A patent/AU2010201696B2/en not_active Expired
- 2010-07-26 JP JP2010166914A patent/JP5721357B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP5422099B2 (ja) | 2014-02-19 |
| CN102321641A (zh) | 2012-01-18 |
| WO2005038033A2 (en) | 2005-04-28 |
| AU2010201695A1 (en) | 2010-05-20 |
| AU2010201696B2 (en) | 2011-10-20 |
| WO2005038033A8 (en) | 2005-07-14 |
| ES2377868T3 (es) | 2012-04-02 |
| JP2007508821A (ja) | 2007-04-12 |
| ATE536415T1 (de) | 2011-12-15 |
| AU2004282576A1 (en) | 2005-04-28 |
| EP1675957B1 (en) | 2011-12-07 |
| AU2004282576B2 (en) | 2010-01-28 |
| AU2010201695B2 (en) | 2012-06-28 |
| JP5721357B2 (ja) | 2015-05-20 |
| PL1675957T3 (pl) | 2012-06-29 |
| AU2010201696A1 (en) | 2010-05-20 |
| JP2010279377A (ja) | 2010-12-16 |
| EP1675957A1 (en) | 2006-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved |
Owner name: U.S. SMOKELESS TOBACCO COMPANY LLC (US) Free format text: NOME ALTERADO DE: U.S. SMOKELESS TOBACCO COMPANY |
|
| B25G | Requested change of headquarter approved |
Owner name: U.S. SMOKELESS TOBACCO COMPANY LLC (US) Free format text: ENDERECO ALTERADO CONFORME SOLICITADO NA PETICAO NO 020120016181/RJ DE 27/02/2012. |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 24, 8O C/C 13, 10, 22, 18 E 25 DA LPI. |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |