BRPI0413745A - horário mde dosagem para agentes anticancerìgenos erbb2 - Google Patents
horário mde dosagem para agentes anticancerìgenos erbb2Info
- Publication number
- BRPI0413745A BRPI0413745A BRPI0413745-0A BRPI0413745A BRPI0413745A BR PI0413745 A BRPI0413745 A BR PI0413745A BR PI0413745 A BRPI0413745 A BR PI0413745A BR PI0413745 A BRPI0413745 A BR PI0413745A
- Authority
- BR
- Brazil
- Prior art keywords
- erbb2
- mammal
- relates
- anticancer agents
- dosing schedule
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 abstract 4
- 239000003112 inhibitor Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 241000124008 Mammalia Species 0.000 abstract 3
- 101710100968 Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 abstract 3
- 230000002018 overexpression Effects 0.000 abstract 2
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49591903P | 2003-08-18 | 2003-08-18 | |
| PCT/IB2004/002580 WO2005016347A1 (en) | 2003-08-18 | 2004-08-06 | Dosing schedule for erbb2 anticancer agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0413745A true BRPI0413745A (pt) | 2006-10-24 |
Family
ID=34193358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0413745-0A BRPI0413745A (pt) | 2003-08-18 | 2004-08-06 | horário mde dosagem para agentes anticancerìgenos erbb2 |
Country Status (18)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003064383A2 (en) | 2002-02-01 | 2003-08-07 | Ariad Gene Therapeutics, Inc. | Phosphorus-containing compounds & uses thereof |
| US8505468B2 (en) * | 2002-11-19 | 2013-08-13 | Sharp Kabushiki Kaisha | Substrate accommodating tray |
| RU2350605C2 (ru) * | 2003-08-14 | 2009-03-27 | Эррей Байофарма Инк. | Аналоги хиназолина в качестве ингибиторов рецепторных тирозинкиназ |
| US7501427B2 (en) | 2003-08-14 | 2009-03-10 | Array Biopharma, Inc. | Quinazoline analogs as receptor tyrosine kinase inhibitors |
| DK1667992T3 (da) | 2003-09-19 | 2007-04-30 | Astrazeneca Ab | Quinazolinderivater |
| RS52119B (sr) * | 2004-05-06 | 2012-08-31 | Warner-Lambert Company Llc | 4-fenilamino-hinazolin-6-il-amidi |
| GB0427131D0 (en) * | 2004-12-10 | 2005-01-12 | Glaxosmithkline Biolog Sa | Novel combination |
| JP2008542354A (ja) * | 2005-06-03 | 2008-11-27 | ファイザー・プロダクツ・インク | 癌治療におけるerbB2阻害剤と他の治療薬の併用 |
| KR20080027253A (ko) * | 2005-06-16 | 2008-03-26 | 미리어드 제네틱스, 인크. | 약제학적 조성물 및 이의 용도 |
| JP2009502960A (ja) * | 2005-07-27 | 2009-01-29 | ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システム | 膵臓癌の処置のためのゲムシタビンおよびチロシンキナーゼ阻害剤を含む組み合わせ |
| US8945573B2 (en) * | 2005-09-08 | 2015-02-03 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Targeted identification of immunogenic peptides |
| JP5709354B2 (ja) * | 2005-11-14 | 2015-04-30 | アリアド・ファーマシューティカルズ・インコーポレイテッド | mTOR阻害剤投与によるがん患者の治療 |
| WO2007059257A2 (en) | 2005-11-15 | 2007-05-24 | Array Biopharma Inc. | N4-phenyl-quinaz0line-4 -amine derivatives and related compounds as erbb type i receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases |
| JP2009532358A (ja) * | 2006-03-31 | 2009-09-10 | マサチューセッツ・インスティテュート・オブ・テクノロジー | 突然変異型egf受容体を発現する腫瘍の治療 |
| EP2004165A2 (en) * | 2006-04-05 | 2008-12-24 | Novartis Pharma AG | Synergistic combinations of anticancer agents for treating cancer |
| US20080161335A1 (en) | 2006-11-14 | 2008-07-03 | Vladyka Ronald S | Oral formulations |
| WO2008124828A1 (en) * | 2007-04-10 | 2008-10-16 | Myriad Genetics, Inc. | Methods for treating vascular disruption disorders |
| CA2720983A1 (en) * | 2007-04-10 | 2008-10-16 | Myrexis, Inc. | Method of treating melanoma |
| NZ580869A (en) * | 2007-04-10 | 2011-02-25 | Myriad Pharmaceuticals Inc | Methods for treating cancer |
| WO2008124824A1 (en) * | 2007-04-10 | 2008-10-16 | Myriad Genetics, Inc. | Dosages and methods for the treatment of cancer |
| JP2010523696A (ja) * | 2007-04-10 | 2010-07-15 | ミリアド ファーマシューティカルズ, インコーポレイテッド | 脳腫瘍を治療する方法 |
| US9551033B2 (en) | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
| EP2592156B1 (en) | 2007-06-08 | 2016-04-20 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
| US8252805B2 (en) * | 2008-05-07 | 2012-08-28 | Teva Pharmaceutical Industries Ltd. | Forms of lapatinib ditosylate and processes for preparation thereof |
| WO2010027848A2 (en) * | 2008-08-26 | 2010-03-11 | Teva Pharmaceutical Industries Ltd. | Forms of lapatinib compounds and processes for the preparation thereof |
| NZ594665A (en) | 2009-03-20 | 2013-08-30 | Genentech Inc | Bispecific anti-her antibodies |
| HK1203378A1 (en) | 2011-11-23 | 2015-10-30 | Intellikine, Llc | Enhanced treatment regimens using mtor inhibitors |
| SG11201606193RA (en) | 2014-01-31 | 2016-08-30 | Toppan Printing Co Ltd | Biomolecule analysis kit and biomolecule analysis method |
| US11160871B2 (en) | 2015-10-28 | 2021-11-02 | Tarveda Therapeutics, Inc. | SSTR-targeted conjugates and particles and formulations thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA932522B (en) * | 1992-04-10 | 1993-12-20 | Res Dev Foundation | Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens |
| WO1996030347A1 (en) * | 1995-03-30 | 1996-10-03 | Pfizer Inc. | Quinazoline derivatives |
| GB9718972D0 (en) * | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| OA12291A (en) * | 2000-06-22 | 2004-03-18 | Pfizer Prod Inc | Substituted bicyclic derivatives for the treatmentof abnormal cell growth. |
| MXPA04004107A (es) * | 2001-12-12 | 2004-07-23 | Pfizer Prod Inc | Moleculas pequenas para el tratamiento del crecimiento celular anormal. |
| PL370858A1 (en) * | 2001-12-12 | 2005-05-30 | Pfizer Products Inc. | Salt forms of e-2-methoxy-n-(3-{4-[3-methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide and method of production |
| EP1567506A4 (en) * | 2002-11-20 | 2007-06-20 | Array Biopharma Inc | CYANOGUANIDINES AND CYANOAMIDINES AS INHIBITORS OF ERBB2 AND EGFR |
| PL377686A1 (pl) * | 2002-12-18 | 2006-02-06 | Pfizer Products Inc. | Pochodne 4-anilinochinazoliny do leczenia anormalnego wzrostu komórek |
-
2004
- 2004-08-06 JP JP2006523695A patent/JP2007502807A/ja not_active Withdrawn
- 2004-08-06 SG SG200706063-5A patent/SG135193A1/en unknown
- 2004-08-06 MX MXPA06001989A patent/MXPA06001989A/es not_active Application Discontinuation
- 2004-08-06 KR KR1020067003190A patent/KR20060037447A/ko not_active Ceased
- 2004-08-06 WO PCT/IB2004/002580 patent/WO2005016347A1/en not_active Ceased
- 2004-08-06 RU RU2006102125/14A patent/RU2328287C2/ru not_active IP Right Cessation
- 2004-08-06 CA CA002536140A patent/CA2536140A1/en not_active Abandoned
- 2004-08-06 CN CNA200480023705XA patent/CN1838959A/zh active Pending
- 2004-08-06 AU AU2004264726A patent/AU2004264726A1/en not_active Abandoned
- 2004-08-06 BR BRPI0413745-0A patent/BRPI0413745A/pt not_active IP Right Cessation
- 2004-08-06 EP EP04744217A patent/EP1658080A1/en not_active Withdrawn
- 2004-08-06 KR KR1020087000092A patent/KR20080014144A/ko not_active Withdrawn
- 2004-08-17 TW TW093124706A patent/TW200522966A/zh unknown
- 2004-08-17 US US10/919,831 patent/US20050119288A1/en not_active Abandoned
- 2004-08-17 AR ARP040102941A patent/AR045268A1/es not_active Application Discontinuation
-
2006
- 2006-01-12 IL IL173127A patent/IL173127A0/en unknown
- 2006-01-18 ZA ZA200600517A patent/ZA200600517B/xx unknown
- 2006-02-15 CO CO06015089A patent/CO5670356A2/es not_active Application Discontinuation
- 2006-03-17 NO NO20061252A patent/NO20061252L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007502807A (ja) | 2007-02-15 |
| SG135193A1 (en) | 2007-09-28 |
| US20050119288A1 (en) | 2005-06-02 |
| EP1658080A1 (en) | 2006-05-24 |
| CO5670356A2 (es) | 2006-08-31 |
| KR20060037447A (ko) | 2006-05-03 |
| KR20080014144A (ko) | 2008-02-13 |
| AU2004264726A1 (en) | 2005-02-24 |
| RU2328287C2 (ru) | 2008-07-10 |
| WO2005016347A1 (en) | 2005-02-24 |
| AR045268A1 (es) | 2005-10-19 |
| TW200522966A (en) | 2005-07-16 |
| MXPA06001989A (es) | 2006-05-17 |
| RU2006102125A (ru) | 2007-09-27 |
| IL173127A0 (en) | 2006-06-11 |
| CN1838959A (zh) | 2006-09-27 |
| NO20061252L (no) | 2006-05-16 |
| ZA200600517B (en) | 2007-02-28 |
| CA2536140A1 (en) | 2005-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |