BRPI0411431A - stents biodegradáveis - Google Patents

stents biodegradáveis

Info

Publication number
BRPI0411431A
BRPI0411431A BRPI0411431-0A BRPI0411431A BRPI0411431A BR PI0411431 A BRPI0411431 A BR PI0411431A BR PI0411431 A BRPI0411431 A BR PI0411431A BR PI0411431 A BRPI0411431 A BR PI0411431A
Authority
BR
Brazil
Prior art keywords
biodegradable stents
biodegradable
stents
vascular
application
Prior art date
Application number
BRPI0411431-0A
Other languages
English (en)
Inventor
Peter Simon
Andreas Lendlein
Birgit Schnitter
Original Assignee
Mnemoscience Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10357747A external-priority patent/DE10357747A1/de
Priority claimed from DE10357744A external-priority patent/DE10357744A1/de
Application filed by Mnemoscience Gmbh filed Critical Mnemoscience Gmbh
Publication of BRPI0411431A publication Critical patent/BRPI0411431A/pt
Publication of BRPI0411431B1 publication Critical patent/BRPI0411431B1/pt
Publication of BRPI0411431B8 publication Critical patent/BRPI0411431B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/16—Materials with shape-memory or superelastic properties

Abstract

"STENTS BIODEGRADáVEIS". A presente invenção refere-se a um stent biodegradável, produzido de um material de SMP, para aplicação na área vascular ou não vascular.
BRPI0411431A 2003-06-13 2004-06-09 stents biodegradáveis BRPI0411431B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10326778 2003-06-13
DE10326782 2003-06-13
DE10357747A DE10357747A1 (de) 2003-06-13 2003-12-10 Temporäre bioabbaubare Stents zur nicht-vaskulären Verwendung
DE10357744A DE10357744A1 (de) 2003-06-13 2003-12-10 Temporäre bioabbaubare Stents
PCT/EP2004/006261 WO2004110515A1 (de) 2003-06-13 2004-06-09 Bioabbaubare stents

Publications (3)

Publication Number Publication Date
BRPI0411431A true BRPI0411431A (pt) 2006-07-25
BRPI0411431B1 BRPI0411431B1 (pt) 2018-12-26
BRPI0411431B8 BRPI0411431B8 (pt) 2021-06-22

Family

ID=33556476

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0411431A BRPI0411431B8 (pt) 2003-06-13 2004-06-09 stents biodegradáveis

Country Status (5)

Country Link
US (1) US20060287710A1 (pt)
EP (1) EP1633410B1 (pt)
BR (1) BRPI0411431B8 (pt)
CA (1) CA2527975C (pt)
WO (1) WO2004110515A1 (pt)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7351421B2 (en) * 1996-11-05 2008-04-01 Hsing-Wen Sung Drug-eluting stent having collagen drug carrier chemically treated with genipin
US7794494B2 (en) 2002-10-11 2010-09-14 Boston Scientific Scimed, Inc. Implantable medical devices
US7976936B2 (en) 2002-10-11 2011-07-12 University Of Connecticut Endoprostheses
WO2005044361A1 (en) 2003-11-07 2005-05-19 Merlin Md Pte Ltd Implantable medical devices with enhanced visibility, mechanical properties and biocompatibility
DE10361942A1 (de) * 2003-12-24 2005-07-21 Restate Patent Ag Radioopaker Marker für medizinische Implantate
US8715340B2 (en) 2004-03-31 2014-05-06 Merlin Md Pte Ltd. Endovascular device with membrane
US8500751B2 (en) 2004-03-31 2013-08-06 Merlin Md Pte Ltd Medical device
US8915952B2 (en) 2004-03-31 2014-12-23 Merlin Md Pte Ltd. Method for treating aneurysms
SG133420A1 (en) * 2005-12-13 2007-07-30 Merlin Md Pte Ltd An endovascular device with membrane having permanently attached agents
US8043361B2 (en) 2004-12-10 2011-10-25 Boston Scientific Scimed, Inc. Implantable medical devices, and methods of delivering the same
EP1681077A1 (en) * 2005-01-12 2006-07-19 Acrostak Corp. A positioning device and a procedure for treating the walls of a resection cavity
DE102005003188A1 (de) 2005-01-20 2006-07-27 Restate Patent Ag Medizinisches Implantat aus einer amorphen oder nanokristallinen Legierung
WO2006086304A1 (en) * 2005-02-08 2006-08-17 Wilson-Cook Medical Inc. Self contracting stent
CN100400114C (zh) * 2005-04-30 2008-07-09 中国科学院金属研究所 可控降解速率的生物医用植入材料及其应用
US20070010740A1 (en) * 2005-05-19 2007-01-11 Biophan Technologies, Inc. Electromagnetic resonant circuit sleeve for implantable medical device
ES2356174T3 (es) * 2005-07-25 2011-04-05 Invatec S.P.A. Prótesis endoluminal con partes bioabsorbibles.
US20070038290A1 (en) * 2005-08-15 2007-02-15 Bin Huang Fiber reinforced composite stents
US20070061006A1 (en) * 2005-09-14 2007-03-15 Nathan Desatnik Methods of making shape memory films by chemical vapor deposition and shape memory devices made thereby
DE102005056532A1 (de) * 2005-11-28 2007-05-31 Mnemoscience Gmbh Entfernung von tubulären Gewebestützen
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US20070224244A1 (en) * 2006-03-22 2007-09-27 Jan Weber Corrosion resistant coatings for biodegradable metallic implants
US20070225799A1 (en) * 2006-03-24 2007-09-27 Medtronic Vascular, Inc. Stent, intraluminal stent delivery system, and method of treating a vascular condition
EP2015794A2 (en) * 2006-04-25 2009-01-21 SurModics, Inc. Hydrophilic shape memory insertable medical articles
EP2040771A2 (en) * 2006-05-16 2009-04-01 Medtronic Vascular, Inc. Bioabsorbable magnesium-reinforced polymer stents
US7818084B2 (en) * 2006-06-16 2010-10-19 The Invention Science Fund, I, LLC Methods and systems for making a blood vessel sleeve
EP2049172B1 (en) 2006-07-25 2014-12-31 Coloplast A/S Photo-curing of thermoplastic coatings
US20080033522A1 (en) * 2006-08-03 2008-02-07 Med Institute, Inc. Implantable Medical Device with Particulate Coating
US20080085946A1 (en) * 2006-08-14 2008-04-10 Mather Patrick T Photo-tailored shape memory article, method, and composition
US8808726B2 (en) 2006-09-15 2014-08-19 Boston Scientific Scimed. Inc. Bioerodible endoprostheses and methods of making the same
DE102006058755A1 (de) * 2006-12-08 2008-06-12 Gkss-Forschungszentrum Geesthacht Gmbh Verfahren zur Herstellung eines alternierenden Multiblockcopolymers mit Formgedächtnis
US20130150943A1 (en) 2007-01-19 2013-06-13 Elixir Medical Corporation Biodegradable endoprostheses and methods for their fabrication
US8814930B2 (en) * 2007-01-19 2014-08-26 Elixir Medical Corporation Biodegradable endoprosthesis and methods for their fabrication
US8182890B2 (en) * 2007-01-19 2012-05-22 Elixir Medical Corporation Biodegradable endoprostheses and methods for their fabrication
KR100838809B1 (ko) * 2007-05-03 2008-06-17 성균관대학교산학협력단 겔강도가 우수한 온도 및 피에치 민감성 블록 공중합체 및이의 제조방법과 이를 이용한 약물전달체
DE102007029672A1 (de) * 2007-06-27 2009-01-02 Lzh Laserzentrum Hannover E.V. Implantat und Verfahren zu dessen Herstellung
KR101240150B1 (ko) 2007-09-12 2013-03-07 트랜스루미널 테크놀로지스, 엘엘씨 봉합 장치, 전개 장치 및 봉합 장치를 전개하기 위한 방법
US9456816B2 (en) 2007-09-12 2016-10-04 Transluminal Technologies, Llc Closure device, deployment apparatus, and method of deploying a closure device
US8876861B2 (en) 2007-09-12 2014-11-04 Transluminal Technologies, Inc. Closure device, deployment apparatus, and method of deploying a closure device
US20090240323A1 (en) * 2008-03-20 2009-09-24 Medtronic Vascular, Inc. Controlled Degradation of Magnesium Stents
US8298466B1 (en) 2008-06-27 2012-10-30 Abbott Cardiovascular Systems Inc. Method for fabricating medical devices with porous polymeric structures
US8262692B2 (en) 2008-09-05 2012-09-11 Merlin Md Pte Ltd Endovascular device
US20100249912A1 (en) * 2009-03-30 2010-09-30 Wilson-Cook Medical Inc. Intraluminal device with controlled biodegradation
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US9163114B2 (en) 2010-08-25 2015-10-20 University Of Massachusetts Biodegradable shape memory polymer
US9155530B2 (en) 2010-11-09 2015-10-13 Transluminal Technologies, Llc Specially designed magnesium-aluminum alloys and medical uses thereof in a hemodynamic environment
US8734703B2 (en) 2010-11-11 2014-05-27 Spirit Aerosystems, Inc. Methods and systems for fabricating composite parts using a SMP apparatus as a rigid lay-up tool and bladder
US8945325B2 (en) 2010-11-11 2015-02-03 Spirit AreoSystems, Inc. Methods and systems for forming integral composite parts with a SMP apparatus
US8608890B2 (en) 2010-11-11 2013-12-17 Spirit Aerosystems, Inc. Reconfigurable shape memory polymer tooling supports
US8815145B2 (en) 2010-11-11 2014-08-26 Spirit Aerosystems, Inc. Methods and systems for fabricating composite stiffeners with a rigid/malleable SMP apparatus
ES2943709T3 (es) 2012-04-06 2023-06-15 Merlin Md Pte Ltd Dispositivos para tratar un aneurisma
US9566666B2 (en) 2013-03-13 2017-02-14 Abbott Cardiovascular Systems Inc. Short pulse laser machining of polymers enhanced with light absorbers for fabricating medical devices
CA2914056A1 (en) * 2013-05-31 2014-12-24 University Of Massachusetts Medical School Elastomeric and degradable polymer mineral composite scaffolds
US10532125B1 (en) 2013-06-27 2020-01-14 Vanderbilt University Shape memory polymers and methods of use
US10293044B2 (en) 2014-04-18 2019-05-21 Auburn University Particulate formulations for improving feed conversion rate in a subject
CA2945925C (en) 2014-04-18 2023-06-20 Auburn University Particulate vaccine formulations for inducing innate and adaptive immunity
US9259339B1 (en) 2014-08-15 2016-02-16 Elixir Medical Corporation Biodegradable endoprostheses and methods of their fabrication
US9480588B2 (en) 2014-08-15 2016-11-01 Elixir Medical Corporation Biodegradable endoprostheses and methods of their fabrication
US9855156B2 (en) 2014-08-15 2018-01-02 Elixir Medical Corporation Biodegradable endoprostheses and methods of their fabrication
US9730819B2 (en) * 2014-08-15 2017-08-15 Elixir Medical Corporation Biodegradable endoprostheses and methods of their fabrication
US10583199B2 (en) 2016-04-26 2020-03-10 Northwestern University Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs
EP3861961A1 (en) 2016-05-16 2021-08-11 Elixir Medical Corporation Uncaging stent
US11622872B2 (en) 2016-05-16 2023-04-11 Elixir Medical Corporation Uncaging stent

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2561853B2 (ja) * 1988-01-28 1996-12-11 株式会社ジェイ・エム・エス 形状記憶性を有する成形体及びその使用方法
US5964744A (en) * 1993-01-04 1999-10-12 Menlo Care, Inc. Polymeric medical device systems having shape memory
JPH08509642A (ja) * 1993-04-28 1996-10-15 フォーカル，インコーポレイテッド 管腔内フォトサーモフォーミングの装置およびその方法
US5716410A (en) * 1993-04-30 1998-02-10 Scimed Life Systems, Inc. Temporary stent and method of use
DE19731021A1 (de) * 1997-07-18 1999-01-21 Meyer Joerg In vivo abbaubares metallisches Implantat
AU758800B2 (en) * 1998-02-23 2003-03-27 Gkss-Forschungszentrum Geesthacht Gmbh Shape memory polymers
HU222543B1 (hu) * 1998-02-23 2003-08-28 Massachusetts Institute Of Technology Biológiai úton lebomlani képes emlékező polimerek
EP0966979B1 (de) * 1998-06-25 2006-03-08 Biotronik AG Implantierbare, bioresorbierbare Gefässwandstütze, insbesondere Koronarstent
AU760819B2 (en) * 1998-09-08 2003-05-22 Kabushikikaisha Igaki Iryo Sekkei Stent for vessels
DE69822470T2 (de) * 1998-11-12 2005-01-20 Takiron Co. Ltd. Bioabbaubares, absorbierbares Formgedächtnismaterial
US6348067B1 (en) * 1998-11-25 2002-02-19 Israel Aircraft Industries Ltd. Method and system with shape memory heating apparatus for temporarily supporting a tubular organ
WO2004006885A2 (de) * 2002-07-10 2004-01-22 Mnemoscience Gmbh Wirkstofffreisetzungssysteme auf basis von bioabbaubaren oder biokompatiblen polymeren mit formgedächtniseffekt
US20020103526A1 (en) * 2000-12-15 2002-08-01 Tom Steinke Protective coating for stent
US7083642B2 (en) * 2000-12-22 2006-08-01 Avantec Vascular Corporation Delivery of therapeutic capable agents
US6872433B2 (en) * 2001-03-27 2005-03-29 The Regents Of The University Of California Shape memory alloy/shape memory polymer tools
US20030153971A1 (en) * 2002-02-14 2003-08-14 Chandru Chandrasekaran Metal reinforced biodegradable intraluminal stents
DE10217350C1 (de) * 2002-04-18 2003-12-18 Mnemoscience Gmbh Polyesterurethane
DE10217351B3 (de) * 2002-04-18 2004-02-12 Mnemoscience Gmbh Interpenetrierende Netzwerke
US7138477B2 (en) * 2002-08-27 2006-11-21 Acushnet Company Compositions for golf equipment
DE10253634A1 (de) * 2002-11-13 2004-05-27 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Endoprothese
WO2004110313A1 (de) * 2003-06-13 2004-12-23 Mnemoscience Gmbh Stents

Also Published As

Publication number Publication date
BRPI0411431B1 (pt) 2018-12-26
EP1633410B1 (de) 2017-05-17
US20060287710A1 (en) 2006-12-21
CA2527975A1 (en) 2004-12-23
BRPI0411431B8 (pt) 2021-06-22
EP1633410A1 (de) 2006-03-15
WO2004110515A1 (de) 2004-12-23
CA2527975C (en) 2011-08-09

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE)

Free format text: TRANSFERIDO DE: MNEMOSCIENCE GMBH

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 26/12/2018, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/06/2004, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 19A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2726 DE 04-04-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.