BR9915820A - Uso clìnico de tiazolidinadionas sozinhas ou emconjunto com outros agentes para bloquear asações mediadas pela oxitocina, tal comocontrações uterinas em parto prematuro oulactação - Google Patents
Uso clìnico de tiazolidinadionas sozinhas ou emconjunto com outros agentes para bloquear asações mediadas pela oxitocina, tal comocontrações uterinas em parto prematuro oulactaçãoInfo
- Publication number
- BR9915820A BR9915820A BR9915820-5A BR9915820A BR9915820A BR 9915820 A BR9915820 A BR 9915820A BR 9915820 A BR9915820 A BR 9915820A BR 9915820 A BR9915820 A BR 9915820A
- Authority
- BR
- Brazil
- Prior art keywords
- oxytocin
- uterine contractions
- agents
- conjunction
- clinical use
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
Patente de Invenção: "USO CLìNICO DE TIAZOLIDINADIONASSOZINHAS OU EM CONJUNTO COM OUTROS AGENTES PARABLOQUEAR AS AçõES MEDIADAS PELA OXITOCINA, TALCOMO CONTRAçõES UTERINAS EM PARTO PREMATURO OULACTAçãO". A presente invenção fornece métodos de prevenirou reduzir a ação mediada pela oxitocina empregando-se umatiazolidinadiona, tal como troglitazona, ou compostos tipotiazolidinadiona. Estes métodos descrevem o emprego destescompostos sozinhos ou em combinação com pelo menos um outroagente, tal como um agente tocolítico. Isto oferece um novoregime terapêutico para o tratamento de ações mediadas pelaoxitocina, por exemplo indução de contrações uterinas, liberaçãode prostagiandina, e enfraquecimento do leite. Portanto, ascondições tais como parto prematuro e parto antes da liberação deCesareana podem ser tratadas por estes métodos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10613398P | 1998-10-29 | 1998-10-29 | |
| PCT/US1999/025433 WO2000025781A1 (en) | 1998-10-29 | 1999-10-29 | Use of thiazolidinediones derivatives for preventing uterine contractions in premature labour or lactation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9915820A true BR9915820A (pt) | 2001-10-30 |
Family
ID=22309672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9915820-5A BR9915820A (pt) | 1998-10-29 | 1999-10-29 | Uso clìnico de tiazolidinadionas sozinhas ou emconjunto com outros agentes para bloquear asações mediadas pela oxitocina, tal comocontrações uterinas em parto prematuro oulactação |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7528133B1 (pt) |
| EP (1) | EP1126844A1 (pt) |
| JP (1) | JP2002528500A (pt) |
| KR (1) | KR20010089381A (pt) |
| CN (1) | CN1328456A (pt) |
| AU (1) | AU1330800A (pt) |
| BR (1) | BR9915820A (pt) |
| CA (1) | CA2348910A1 (pt) |
| CZ (1) | CZ20011524A3 (pt) |
| HK (1) | HK1041213A1 (pt) |
| HU (1) | HUP0104900A3 (pt) |
| ID (1) | ID29352A (pt) |
| IL (1) | IL142841A0 (pt) |
| MX (1) | MXPA01004257A (pt) |
| NO (1) | NO20012090L (pt) |
| PL (1) | PL347508A1 (pt) |
| TR (1) | TR200101882T2 (pt) |
| WO (1) | WO2000025781A1 (pt) |
| ZA (1) | ZA200103999B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004062563A2 (en) * | 2003-01-16 | 2004-07-29 | Université de Lausanne | Methods for screening for therapeutic agents that are useful in the treatment of oxytocin and vasopressin-related disorders |
| US20150004144A1 (en) | 2011-12-02 | 2015-01-01 | The General Hospital Corporation | Differentiation into brown adipocytes |
| WO2014066568A1 (en) | 2012-10-24 | 2014-05-01 | Winthrop-University Hospital | Non-invasive biomarker to identify subjects at risk of preterm delivery |
| US10555934B2 (en) * | 2016-01-04 | 2020-02-11 | ObsEva S.A. | Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof |
| JP2020533595A (ja) | 2017-09-13 | 2020-11-19 | プロジェニティ， インコーポレイテッド | 子癇前症バイオマーカならびに関連するシステムおよび方法 |
| EP4070113A4 (en) | 2019-12-04 | 2023-12-20 | Biora Therapeutics, Inc. | ASSESSMENT OF PREECAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR ASSAYS |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478852C1 (en) * | 1993-09-15 | 2001-03-13 | Sankyo Co | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus |
| US5370135A (en) * | 1993-10-13 | 1994-12-06 | Biex, Inc. | Use of estriol measurement to monitor tocolytic therapy |
| TW438587B (en) | 1995-06-20 | 2001-06-07 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
| EP0783888A1 (en) * | 1995-12-26 | 1997-07-16 | Sankyo Company Limited | Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis |
| EP0844997A1 (en) * | 1996-06-19 | 1998-06-03 | Dr. Reddy's Research Foundation | Novel polymorphic forms of troglitazone having enhanced anti-diabetic activity and a process for their preparation |
| US5814647A (en) * | 1997-03-04 | 1998-09-29 | Board Of Regents, The University Of Texas System | Use of troglitazone and related compounds for the treatment of the climacteric symptoms |
-
1999
- 1999-10-29 WO PCT/US1999/025433 patent/WO2000025781A1/en not_active Application Discontinuation
- 1999-10-29 IL IL14284199A patent/IL142841A0/xx unknown
- 1999-10-29 MX MXPA01004257A patent/MXPA01004257A/es unknown
- 1999-10-29 EP EP99956774A patent/EP1126844A1/en not_active Withdrawn
- 1999-10-29 US US10/069,744 patent/US7528133B1/en not_active Expired - Fee Related
- 1999-10-29 BR BR9915820-5A patent/BR9915820A/pt not_active IP Right Cessation
- 1999-10-29 CN CN99813856A patent/CN1328456A/zh active Pending
- 1999-10-29 HU HU0104900A patent/HUP0104900A3/hu unknown
- 1999-10-29 JP JP2000579222A patent/JP2002528500A/ja not_active Withdrawn
- 1999-10-29 ID IDW00200101157A patent/ID29352A/id unknown
- 1999-10-29 KR KR1020017005411A patent/KR20010089381A/ko not_active Application Discontinuation
- 1999-10-29 TR TR2001/01882T patent/TR200101882T2/xx unknown
- 1999-10-29 CZ CZ20011524A patent/CZ20011524A3/cs unknown
- 1999-10-29 PL PL99347508A patent/PL347508A1/xx not_active Application Discontinuation
- 1999-10-29 CA CA002348910A patent/CA2348910A1/en not_active Abandoned
- 1999-10-29 AU AU13308/00A patent/AU1330800A/en not_active Abandoned
-
2001
- 2001-04-27 NO NO20012090A patent/NO20012090L/no not_active Application Discontinuation
- 2001-05-16 ZA ZA200103999A patent/ZA200103999B/en unknown
-
2002
- 2002-04-15 HK HK02102806.8A patent/HK1041213A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TR200101882T2 (tr) | 2001-12-21 |
| US7528133B1 (en) | 2009-05-05 |
| KR20010089381A (ko) | 2001-10-06 |
| HUP0104900A2 (hu) | 2002-04-29 |
| NO20012090D0 (no) | 2001-04-27 |
| HUP0104900A3 (en) | 2003-02-28 |
| CN1328456A (zh) | 2001-12-26 |
| PL347508A1 (en) | 2002-04-08 |
| CZ20011524A3 (cs) | 2002-01-16 |
| EP1126844A1 (en) | 2001-08-29 |
| ZA200103999B (en) | 2002-08-16 |
| IL142841A0 (en) | 2002-03-10 |
| CA2348910A1 (en) | 2000-05-11 |
| JP2002528500A (ja) | 2002-09-03 |
| AU1330800A (en) | 2000-05-22 |
| ID29352A (id) | 2001-08-23 |
| MXPA01004257A (es) | 2002-06-21 |
| HK1041213A1 (zh) | 2002-07-05 |
| NO20012090L (no) | 2001-06-27 |
| WO2000025781A1 (en) | 2000-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007. |