BR9915667A - Uso de benzoilguanidinas para o tratamento de diabetes melitus não dependente de insulina - Google Patents

Uso de benzoilguanidinas para o tratamento de diabetes melitus não dependente de insulina

Info

Publication number
BR9915667A
BR9915667A BR9915667-9A BR9915667A BR9915667A BR 9915667 A BR9915667 A BR 9915667A BR 9915667 A BR9915667 A BR 9915667A BR 9915667 A BR9915667 A BR 9915667A
Authority
BR
Brazil
Prior art keywords
het
hal
atoms
treatment
insulin
Prior art date
Application number
BR9915667-9A
Other languages
English (en)
Portuguese (pt)
Inventor
Rolf Gericke
Manfred Baumgarth
Klaus Minck
Didier Mesangeau
Liliane Doare
Micheline Kergoat
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BR9915667A publication Critical patent/BR9915667A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4021-aryl substituted, e.g. piretanide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
BR9915667-9A 1998-11-26 1999-11-16 Uso de benzoilguanidinas para o tratamento de diabetes melitus não dependente de insulina BR9915667A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98122419 1998-11-26
PCT/EP1999/008795 WO2000030624A2 (en) 1998-11-26 1999-11-16 Use of benzoylguanidines for the treatment of non-insulin-dependent diabetes mellitus

Publications (1)

Publication Number Publication Date
BR9915667A true BR9915667A (pt) 2001-08-14

Family

ID=8233036

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9915667-9A BR9915667A (pt) 1998-11-26 1999-11-16 Uso de benzoilguanidinas para o tratamento de diabetes melitus não dependente de insulina

Country Status (14)

Country Link
EP (1) EP1131064A2 (id)
JP (1) JP2002530325A (id)
KR (1) KR20010080597A (id)
CN (1) CN1328452A (id)
AR (1) AR023064A1 (id)
AU (1) AU1553500A (id)
BR (1) BR9915667A (id)
CA (1) CA2352154A1 (id)
CZ (1) CZ20011785A3 (id)
HU (1) HUP0104418A2 (id)
ID (1) ID29523A (id)
NO (1) NO20012563D0 (id)
PL (1) PL348152A1 (id)
WO (1) WO2000030624A2 (id)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA008769B1 (ru) * 2002-06-05 2007-08-31 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. Лекарственное средство для лечения диабета
US7381841B2 (en) 2003-08-22 2008-06-03 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them
DE102004054847A1 (de) 2004-11-13 2006-05-24 Sanofi-Aventis Deutschland Gmbh Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4430861A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Heterocyclyl-benzoylguanidine
DE4430916A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Alkyl-benzoylguanidin-Derivate
DE4437874A1 (de) * 1994-10-22 1996-04-25 Merck Patent Gmbh Alkyl-5-methylsulfonyl-benzoylguanidin-Derivate
DE19502644A1 (de) * 1995-01-28 1996-08-01 Merck Patent Gmbh 4-Amino-benzoylguanidin-Derivate
DE19502895A1 (de) * 1995-01-31 1996-08-01 Merck Patent Gmbh 4-Mercapto-benzoylguanidin-Derivate
DE19517848A1 (de) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorhaltige Benzoylguanidine
DE19531138A1 (de) * 1995-08-24 1997-02-27 Merck Patent Gmbh Alkenyl-benzoylguanidin-Derivate

Also Published As

Publication number Publication date
WO2000030624A3 (en) 2000-10-05
CZ20011785A3 (cs) 2001-10-17
AU1553500A (en) 2000-06-13
KR20010080597A (ko) 2001-08-22
HUP0104418A2 (hu) 2002-04-29
AR023064A1 (es) 2002-09-04
NO20012563L (no) 2001-05-25
PL348152A1 (en) 2002-05-06
ID29523A (id) 2001-09-06
WO2000030624A2 (en) 2000-06-02
JP2002530325A (ja) 2002-09-17
NO20012563D0 (no) 2001-05-25
CA2352154A1 (en) 2000-06-02
EP1131064A2 (en) 2001-09-12
CN1328452A (zh) 2001-12-26

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]