PL348152A1 - Use of benzoylguanidines for the treatment of non-insulin-dependent diabetes mellitus - Google Patents

Use of benzoylguanidines for the treatment of non-insulin-dependent diabetes mellitus

Info

Publication number
PL348152A1
PL348152A1 PL99348152A PL34815299A PL348152A1 PL 348152 A1 PL348152 A1 PL 348152A1 PL 99348152 A PL99348152 A PL 99348152A PL 34815299 A PL34815299 A PL 34815299A PL 348152 A1 PL348152 A1 PL 348152A1
Authority
PL
Poland
Prior art keywords
benzoylguanidines
insulin
treatment
diabetes mellitus
dependent diabetes
Prior art date
Application number
PL99348152A
Inventor
Rolf Gericke
Manfred Baumgarth
Klaus Minck
Didier Mesangeau
Liliane Doare
Micheline Kergoat
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL348152A1 publication Critical patent/PL348152A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4021-aryl substituted, e.g. piretanide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL99348152A 1998-11-26 1999-11-16 Use of benzoylguanidines for the treatment of non-insulin-dependent diabetes mellitus PL348152A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98122419 1998-11-26

Publications (1)

Publication Number Publication Date
PL348152A1 true PL348152A1 (en) 2002-05-06

Family

ID=8233036

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99348152A PL348152A1 (en) 1998-11-26 1999-11-16 Use of benzoylguanidines for the treatment of non-insulin-dependent diabetes mellitus

Country Status (14)

Country Link
EP (1) EP1131064A2 (en)
JP (1) JP2002530325A (en)
KR (1) KR20010080597A (en)
CN (1) CN1328452A (en)
AR (1) AR023064A1 (en)
AU (1) AU1553500A (en)
BR (1) BR9915667A (en)
CA (1) CA2352154A1 (en)
CZ (1) CZ20011785A3 (en)
HU (1) HUP0104418A2 (en)
ID (1) ID29523A (en)
NO (1) NO20012563D0 (en)
PL (1) PL348152A1 (en)
WO (1) WO2000030624A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA008769B1 (en) * 2002-06-05 2007-08-31 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. Therapeutic drug for diabetes
US7381841B2 (en) 2003-08-22 2008-06-03 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them
DE102004054847A1 (en) * 2004-11-13 2006-05-24 Sanofi-Aventis Deutschland Gmbh Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, and medicament containing them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4430916A1 (en) * 1994-08-31 1996-03-07 Merck Patent Gmbh Alkyl benzoylguanidine derivatives
DE4430861A1 (en) * 1994-08-31 1996-03-07 Merck Patent Gmbh Heterocyclyl-benzoylguanidines
DE4437874A1 (en) * 1994-10-22 1996-04-25 Merck Patent Gmbh Alkyl 5-methylsulfonylbenzoylguanidine derivatives
DE19502644A1 (en) * 1995-01-28 1996-08-01 Merck Patent Gmbh 4-amino-benzoylguanidine derivatives
DE19502895A1 (en) * 1995-01-31 1996-08-01 Merck Patent Gmbh 4-mercapto-benzoylguanidine derivatives
DE19517848A1 (en) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorine-containing benzoylguanidines
DE19531138A1 (en) * 1995-08-24 1997-02-27 Merck Patent Gmbh Alkenyl benzoylguanidine derivatives

Also Published As

Publication number Publication date
CN1328452A (en) 2001-12-26
BR9915667A (en) 2001-08-14
HUP0104418A2 (en) 2002-04-29
NO20012563L (en) 2001-05-25
ID29523A (en) 2001-09-06
JP2002530325A (en) 2002-09-17
AR023064A1 (en) 2002-09-04
EP1131064A2 (en) 2001-09-12
KR20010080597A (en) 2001-08-22
WO2000030624A3 (en) 2000-10-05
WO2000030624A2 (en) 2000-06-02
NO20012563D0 (en) 2001-05-25
CA2352154A1 (en) 2000-06-02
CZ20011785A3 (en) 2001-10-17
AU1553500A (en) 2000-06-13

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