BR9909434A - Microcápsulas umectáveis tendo núcleos revestidos de polìmero hidrofóbico - Google Patents

Microcápsulas umectáveis tendo núcleos revestidos de polìmero hidrofóbico

Info

Publication number
BR9909434A
BR9909434A BR9909434-7A BR9909434A BR9909434A BR 9909434 A BR9909434 A BR 9909434A BR 9909434 A BR9909434 A BR 9909434A BR 9909434 A BR9909434 A BR 9909434A
Authority
BR
Brazil
Prior art keywords
microcapsules
solvent
wettable
ethylcellulose
surfactants
Prior art date
Application number
BR9909434-7A
Other languages
English (en)
Inventor
Maria Massimo Calanchi
De Luigi Stefano Bruschi
Leonardo Gentilini
Giovanni Luigi Mapelli
Original Assignee
Eurand Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Int filed Critical Eurand Int
Publication of BR9909434A publication Critical patent/BR9909434A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

<B>"MICROCáPSULAS UMECTáVEIS TENDO NúCLEOS REVESTIDOS DE POLìMERO HIDROFóBICO"<D>. A presente invenção se refere a microcápsulas umectáveis tendo núcleos revestidos de polímeros hidrofóbicos e a um processo para sua preparação. Em particular, as microcápsulas com revestimentos de polímero hidrofóbico são umectáveis, de modo que são suspensas em meio aquoso. As microcápsulas umectáveis podem ser preparadas mediante aplicação de polímero hidrofóbico sobre uma droga que contém um núcleo, mediante separação de fase de um solvente para proporcionar microcápsulas, opcionalmente lavando as ditas microcápsulas com um solvente, em que as ditas microcápsulas são substancialmente insolúveis e secas, caracterizado em que (a): um ou mais tensoativos são incorporados no solvente na etapa de separação de fase e/ou (b): um ou mais tensoativos são incorporados no solvente usado para lavar as microcápsulas e/ou (c): a microcápsula é revestida com um ou mais tensoativos opcionalmente na presença de um solvente.
BR9909434-7A 1998-04-09 1999-04-09 Microcápsulas umectáveis tendo núcleos revestidos de polìmero hidrofóbico BR9909434A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98106521 1998-04-09
PCT/EP1999/002430 WO1999052510A1 (en) 1998-04-09 1999-04-09 Wettable microcapsules having hydrophobic polymer coated cores

Publications (1)

Publication Number Publication Date
BR9909434A true BR9909434A (pt) 2000-12-12

Family

ID=8231743

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9909434-7A BR9909434A (pt) 1998-04-09 1999-04-09 Microcápsulas umectáveis tendo núcleos revestidos de polìmero hidrofóbico

Country Status (15)

Country Link
US (1) US6509034B1 (pt)
EP (1) EP1069891B1 (pt)
JP (1) JP4555980B2 (pt)
KR (1) KR20010042547A (pt)
AT (1) ATE213935T1 (pt)
AU (1) AU742009B2 (pt)
BR (1) BR9909434A (pt)
CA (1) CA2328080C (pt)
DE (1) DE69900977T2 (pt)
DK (1) DK1069891T3 (pt)
ES (1) ES2174600T3 (pt)
NZ (1) NZ507951A (pt)
PT (1) PT1069891E (pt)
WO (1) WO1999052510A1 (pt)
ZA (1) ZA200005875B (pt)

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KR100526998B1 (ko) * 2002-01-21 2005-11-08 임대우 홍삼 및 인삼 엑기스 분말을 함유한 마이크로캡슐
KR100466719B1 (ko) * 2002-02-04 2005-01-17 주식회사 일화 홍삼 또는 인삼정분을 함유하는 구형의 미세캡슐 제조방법
DE10227224B4 (de) * 2002-06-18 2005-11-24 Daimlerchrysler Ag Verwendung eines Granulates zum Herstellen eines Gegenstandes mit einem 3D-Binderdruck-Verfahren
BR0303954A (pt) * 2002-10-10 2004-09-08 Int Flavors & Fragrances Inc Composição, fragrância, método para divisão de uma quantidade efetiva olfativa de fragrância em um produto sem enxague e produto sem enxague
KR100963091B1 (ko) * 2003-08-25 2010-06-14 (주)아모레퍼시픽 자외선 흡수제를 함유하는 고분자 캡슐 및 그 제조 방법,및 이를 함유하는 화장료 조성물
US20050113282A1 (en) * 2003-11-20 2005-05-26 Parekh Prabodh P. Melamine-formaldehyde microcapsule slurries for fabric article freshening
US7105064B2 (en) * 2003-11-20 2006-09-12 International Flavors & Fragrances Inc. Particulate fragrance deposition on surfaces and malodour elimination from surfaces
US20050112152A1 (en) * 2003-11-20 2005-05-26 Popplewell Lewis M. Encapsulated materials
US7611630B2 (en) * 2004-03-30 2009-11-03 Bend Research, Inc. Method and device for evaluation of pharmaceutical compositions
US20050226900A1 (en) * 2004-04-13 2005-10-13 Winton Brooks Clint D Skin and hair treatment composition and process for using same resulting in controllably-releasable fragrance and/or malodour counteractant evolution
US20050227907A1 (en) * 2004-04-13 2005-10-13 Kaiping Lee Stable fragrance microcapsule suspension and process for using same
US7594594B2 (en) * 2004-11-17 2009-09-29 International Flavors & Fragrances Inc. Multi-compartment storage and delivery containers and delivery system for microencapsulated fragrances
US20070207174A1 (en) * 2005-05-06 2007-09-06 Pluyter Johan G L Encapsulated fragrance materials and methods for making same
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
DE102005062270A1 (de) * 2005-12-24 2007-06-28 Bayer Technology Services Gmbh Geschmacksmaskierung von Pulvern
US20100062073A1 (en) * 2006-11-29 2010-03-11 Ronald Arthur Beyerinck Pharmaceutical compositions comprising nanoparticles comprising enteric polymers casein
US20100119612A1 (en) * 2007-04-17 2010-05-13 Bend Research, Inc Nanoparticles comprising non-crystalline drug
US20100080852A1 (en) * 2007-05-03 2010-04-01 Ronald Arthur Beyerinck Phamaceutical composition comprising nanoparticles and casein
WO2008135828A2 (en) * 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US8703204B2 (en) * 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
EP2162120B1 (en) * 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
US9545384B2 (en) 2007-06-04 2017-01-17 Bend Research, Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate
WO2009010842A2 (en) * 2007-07-13 2009-01-22 Pfizer Products Inc. Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers
EP2231169B1 (en) * 2007-12-06 2016-05-04 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
US9233078B2 (en) * 2007-12-06 2016-01-12 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
KR100888380B1 (ko) * 2007-12-11 2009-03-13 한국생산기술연구원 계면 활성제를 이용한 유동성 입자의 제조방법 및 이로부터제조되는 유동성 입자
EP2440210A4 (en) * 2009-06-12 2014-01-29 Meritage Pharma Inc METHOD FOR THE TREATMENT OF STOMACH DARM DISEASES
ES2668203T3 (es) 2009-12-02 2018-05-17 Adare Pharmaceuticals S.R.L. Microcápsulas de fexofenadina y composiciones que las contienen
AR105111A1 (es) * 2015-06-26 2017-09-06 Advanced Bionutrition Corp Composición para administración de agentes activos a un animal
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Also Published As

Publication number Publication date
CA2328080C (en) 2008-08-12
JP4555980B2 (ja) 2010-10-06
US6509034B1 (en) 2003-01-21
JP2002511402A (ja) 2002-04-16
AU3522799A (en) 1999-11-01
DE69900977D1 (de) 2002-04-11
PT1069891E (pt) 2002-08-30
KR20010042547A (ko) 2001-05-25
DE69900977T2 (de) 2002-11-14
NZ507951A (en) 2002-12-20
EP1069891B1 (en) 2002-03-06
EP1069891A1 (en) 2001-01-24
AU742009B2 (en) 2001-12-13
ES2174600T3 (es) 2002-11-01
WO1999052510A1 (en) 1999-10-21
ZA200005875B (en) 2002-03-20
ATE213935T1 (de) 2002-03-15
DK1069891T3 (da) 2002-06-24
CA2328080A1 (en) 1999-10-21

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]