BR9907191A - Compostos azatricìclicos - Google Patents

Compostos azatricìclicos

Info

Publication number
BR9907191A
BR9907191A BR9907191-6A BR9907191A BR9907191A BR 9907191 A BR9907191 A BR 9907191A BR 9907191 A BR9907191 A BR 9907191A BR 9907191 A BR9907191 A BR 9907191A
Authority
BR
Brazil
Prior art keywords
hydrogen
substituent
sigma
azathricyl
compounds
Prior art date
Application number
BR9907191-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Peter Anthony Crooks
Niranjan Madhukar Deo
Original Assignee
Reynolds Tobacco Co R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reynolds Tobacco Co R filed Critical Reynolds Tobacco Co R
Publication of BR9907191A publication Critical patent/BR9907191A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BR9907191-6A 1998-04-02 1999-02-26 Compostos azatricìclicos BR9907191A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/054,179 US5986100A (en) 1998-04-02 1998-04-02 Pharmaceutical compositions and methods for use
PCT/US1999/004324 WO1999051601A1 (en) 1998-04-02 1999-02-26 Azatricyclic compounds

Publications (1)

Publication Number Publication Date
BR9907191A true BR9907191A (pt) 2000-12-26

Family

ID=21989278

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907191-6A BR9907191A (pt) 1998-04-02 1999-02-26 Compostos azatricìclicos

Country Status (14)

Country Link
US (2) US5986100A (https=)
EP (1) EP1066287B1 (https=)
JP (1) JP2002510689A (https=)
KR (1) KR100613050B1 (https=)
AT (1) ATE248839T1 (https=)
AU (1) AU2794899A (https=)
BR (1) BR9907191A (https=)
CA (1) CA2317570A1 (https=)
DE (1) DE69910993T2 (https=)
DK (1) DK1066287T3 (https=)
ES (1) ES2205778T3 (https=)
MX (1) MXPA00009624A (https=)
PT (1) PT1066287E (https=)
WO (1) WO1999051601A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093724A (en) * 1998-08-18 2000-07-25 Ucb, S.A. Muscarinic agonists and antagonists
HUP0501017A3 (en) * 2001-12-14 2010-06-28 Targacept Methods and compositions for treatment of central nervous system disorders
US20030162770A1 (en) 2002-02-22 2003-08-28 Davis Bonnie M. Use of modulators of nicotinic receptors for treatment of cognitive dysfunction
US7897766B2 (en) * 2005-09-23 2011-03-01 Abbott Laboratories Amino-aza-adamantane derivatives and methods of use
US8314119B2 (en) * 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
AU2012203831B2 (en) * 2006-11-06 2013-12-19 Abbvie Bahamas Ltd Azaadamantane derivatives and their uses as nicotinic acetylcholine receptors ligands
EP2139891B1 (en) * 2007-03-23 2012-09-05 Abbott Laboratories 4-substituted azaadamantane derivatives and methods of use thereof
ATE538122T1 (de) * 2007-03-23 2012-01-15 Abbott Lab Acetamid- und carboxamid-derivate von azaadamantan sowie verfahren zu ihrer verwendung
PE20131394A1 (es) 2010-09-23 2014-01-11 Abbvie Inc Monohidrato de derivados de aza-adamantano
TWI773657B (zh) 2015-12-18 2022-08-11 美商亞德利克斯公司 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物
US12084472B2 (en) 2015-12-18 2024-09-10 Ardelyx, Inc. Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0412798A3 (en) * 1989-08-08 1992-07-01 Merck Sharp & Dohme Ltd. Substituted pyridines, their preparation, formulations and use in dementia
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
EP0492903A1 (en) * 1990-12-21 1992-07-01 MERCK SHARP & DOHME LTD. Substituted pyrazines, pyrimidines and pyridazines for use in the treatment of glaucoma
AU7474794A (en) * 1993-07-22 1995-02-20 E.I. Du Pont De Nemours And Company Arthropodicidal azacyclic heterocycles
US5510355A (en) * 1994-09-06 1996-04-23 Bencherif; Merouane Depolarizing skeletal muscle relaxants
US5583140A (en) * 1995-05-17 1996-12-10 Bencherif; Merouane Pharmaceutical compositions for the treatment of central nervous system disorders
WO1996036637A1 (en) * 1995-05-17 1996-11-21 R.J. Reynolds Tobacco Company Pharmaceutical compositions for prevention and treatment of central nervous system disorders
US5684159A (en) * 1995-05-30 1997-11-04 Rhone-Poulenc Rorer S.A. L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds

Also Published As

Publication number Publication date
JP2002510689A (ja) 2002-04-09
DE69910993D1 (de) 2003-10-09
MXPA00009624A (es) 2005-06-20
ATE248839T1 (de) 2003-09-15
WO1999051601A1 (en) 1999-10-14
AU2794899A (en) 1999-10-25
US5986100A (en) 1999-11-16
DK1066287T3 (da) 2004-01-19
PT1066287E (pt) 2004-01-30
KR100613050B1 (ko) 2006-08-25
KR20010052172A (ko) 2001-06-25
DE69910993T2 (de) 2004-07-22
CA2317570A1 (en) 1999-10-14
US6211372B1 (en) 2001-04-03
EP1066287A1 (en) 2001-01-10
ES2205778T3 (es) 2004-05-01
EP1066287B1 (en) 2003-09-03

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Legal Events

Date Code Title Description
PC Transfer

Free format text: TARGACEPT, INC. (US)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT. CL: CO7D 471/18; A61K 31/439.

Ipc: C07D 471/18 (2008.04)

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 8O DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.