BR9903992A - ésteres de esterol em formas de dosagem sólida de comprimidos - Google Patents

ésteres de esterol em formas de dosagem sólida de comprimidos

Info

Publication number
BR9903992A
BR9903992A BR9903992-3A BR9903992A BR9903992A BR 9903992 A BR9903992 A BR 9903992A BR 9903992 A BR9903992 A BR 9903992A BR 9903992 A BR9903992 A BR 9903992A
Authority
BR
Brazil
Prior art keywords
dosage forms
tablet dosage
sterol esters
solid tablet
stanol
Prior art date
Application number
BR9903992-3A
Other languages
English (en)
Inventor
Richard D Bruce
John D Higgins
Stephen A Martellucci
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of BR9903992A publication Critical patent/BR9903992A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Patente de Invenção: <B>"éSTERES DE ESTEROL EM FORMAS DE DOSAGEM SóLIDA DE COMPRIMIDOS"<D>. A presente invenção provê um material estanol em uma forma adequada para a fabricação de uma dosagem oral. Um processo para produzir o material estanol é também fornecido.
BR9903992-3A 1998-09-02 1999-09-01 ésteres de esterol em formas de dosagem sólida de comprimidos BR9903992A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/145,528 US6376481B2 (en) 1998-09-02 1998-09-02 Sterol esters in tableted solid dosage forms

Publications (1)

Publication Number Publication Date
BR9903992A true BR9903992A (pt) 2000-09-19

Family

ID=22513518

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9903992-3A BR9903992A (pt) 1998-09-02 1999-09-01 ésteres de esterol em formas de dosagem sólida de comprimidos

Country Status (12)

Country Link
US (1) US6376481B2 (pt)
EP (1) EP0985411B1 (pt)
JP (1) JP2000103737A (pt)
AT (1) ATE282405T1 (pt)
AU (1) AU764513B2 (pt)
BR (1) BR9903992A (pt)
CA (1) CA2281251C (pt)
DE (1) DE69921919T2 (pt)
DK (1) DK0985411T3 (pt)
NO (1) NO994233L (pt)
NZ (1) NZ337574A (pt)
PT (1) PT985411E (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1140027T3 (da) * 1998-12-23 2006-02-27 Alza Corp Doseringsformer indeholdende poröse partikler
US6342249B1 (en) 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
KR20020026053A (ko) * 2000-09-30 2002-04-06 노승권 음료용 식물성 스테롤의 분산방법 및 이를 함유하는 음료
HUP0400281A3 (en) * 2001-06-22 2009-11-30 Pfizer Prod Inc Pharmaceutical compositions of adsorbates of amorphous drug and process for their preparation
JP2005523262A (ja) 2002-02-01 2005-08-04 ファイザー・プロダクツ・インク 薬物及び親油性ミクロ相形成物質の非晶質分散物の医薬組成物
US7994153B2 (en) * 2002-05-20 2011-08-09 Otsuka Pharmaceutical Co., Ltd. Chloasma amelioration composition and dullness amelioration composition
US7335389B2 (en) 2002-06-12 2008-02-26 The Coca-Cola Company Beverages containing plant sterols
US7306819B2 (en) 2002-06-12 2007-12-11 The Coca-Cola Company Beverages containing plant sterols
US6946151B2 (en) * 2002-11-12 2005-09-20 Ayurvedic-Life International, Llc Therapeutic compositions
US6949261B2 (en) 2002-11-12 2005-09-27 Ayurvedic-Life International, Llc Compositions for diabetes treatment and prophylaxis
MXPA06001417A (es) 2003-08-04 2006-05-15 Pfizer Prod Inc Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas.
BRPI0416747A (pt) * 2003-11-20 2007-01-16 Zomanex Llc métodos e formulações para o tratamento de condições médicas relacionadas à dihidrotesterona elevada
US8968768B2 (en) * 2004-03-29 2015-03-03 Wyeth Llc Phytosterol nutritional supplements
KR101573316B1 (ko) * 2004-03-29 2015-12-01 와이어쓰 엘엘씨 종합비타민 및 무기물 영양 보충제
DE102005022953A1 (de) * 2005-05-19 2006-11-23 Chemische Fabrik Budenheim Kg Nahrungsergänzungsmittel
EP2167069B1 (en) 2007-05-23 2011-10-26 Amcol International Corporation Cholesterol-interacting layered phyllosilicates and methods of reducing hypercholesteremia in a mammal
EP2257173B1 (en) * 2008-02-27 2014-07-30 Amcol International Corporation Protonated hydrogen ion-exchanged layered phyllosilicate material for use in treating atherosclerosis
US8039025B1 (en) 2010-10-15 2011-10-18 Life Plus, LLC Methods and dosage forms for the treatment of human cancers
GB201502077D0 (en) * 2015-02-09 2015-03-25 Cubic Pharmaceuticals Ltd And Delta Pharmaceuticals Ltd Improved hme technology

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB284814A (en) 1926-11-29 1928-02-09 Leonard Miller Improvements in or relating to hoists or derricks
US3004043A (en) 1959-10-09 1961-10-10 Eastman Kodak Co Water-soluble vegetable oil sterol derivatives
US3203862A (en) 1960-03-11 1965-08-31 Jones John Harris Oral anti-hypercholesterol composition
US3495011A (en) 1968-10-28 1970-02-10 Unimed Inc Reduction of blood level cholesterol
US3865939A (en) * 1973-02-23 1975-02-11 Procter & Gamble Edible oils having hypocholesterolemic properties
US3881005A (en) 1973-08-13 1975-04-29 Lilly Co Eli Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof
US4160850A (en) 1975-08-25 1979-07-10 General Mills, Inc. Shelf-stable mix for a spreadable butter-substitute
US4195084A (en) 1977-01-07 1980-03-25 Eli Lilly And Company Taste-stable aqueous pharmaceutical suspension of tall oil sitosterols and a method for the preparation thereof
GB1598638A (en) 1978-04-18 1981-09-23 Gen Mills Inc Butter-substitute products comprising an emulsifier water oil and hard fat and compositions and processes for the production thereof
US4238520A (en) 1979-06-28 1980-12-09 Scm Corporation Low-fat comestible spread substitutes
US4588717A (en) 1984-06-13 1986-05-13 David C. Mitchell Medical Research Institute Compounds and vitamin supplements and methods for making same
US4705875A (en) 1984-06-13 1987-11-10 Mitchell David C Substituted fructose compounds and vitamin supplements and methods for making same
US4883788A (en) 1986-06-06 1989-11-28 Hauser-Kuhrts, Inc. Method and composition for reducing serum cholesterol
US4824672A (en) 1986-06-06 1989-04-25 Hauser-Kuhrts, Inc. Method and composition for reducing serum cholesterol
GB8623557D0 (en) * 1986-10-01 1986-11-05 Boots Co Plc Therapeutic agents
US5082684A (en) 1990-02-05 1992-01-21 Pfizer Inc. Low-calorie fat substitute
US5306514A (en) 1990-04-26 1994-04-26 The Procter & Gamble Company Solid, nondigestible, fat-like compounds and food compositions containing same
US5306515A (en) 1990-04-26 1994-04-26 The Procter & Gamble Company Reduced calorie pourable shortening, cooking oils, salad oils or like compositions
US5514398A (en) 1990-11-05 1996-05-07 Amano Pharmaceutical Co., Ltd. Food additive and use thereof
HU217625B (hu) 1991-05-03 2000-03-28 Raisio Benecol Ltd. Új eljárás szérum-koleszterinszint csökkentését szolgáló béta-szitosztanin-zsírsav-észterek és észterkeverékek, valamint ezeket tartalmazó élelmiszerek előállítására
US5338563A (en) 1992-05-01 1994-08-16 Nabisco, Inc. Process for the preparation of a spatter-resistant low-fat spread
GB9220268D0 (en) 1992-09-25 1992-11-11 Unilever Plc Cosmetic composition
US5326825A (en) 1992-11-27 1994-07-05 Naesman Jan H Process for the preparation of a graft copolymer bound catalyst
AU7250694A (en) 1993-06-25 1995-01-17 Biosphere Technologies Inc. Dietary supplement incorporating beta-sitosterol and pectin
US5472728A (en) 1994-04-22 1995-12-05 Kraft Foods, Inc. Edible fat-containing margarine type products and process for preparing same
GB9410867D0 (en) * 1994-05-31 1994-07-20 Ucb Sa Radiation curable compositions
US5770254A (en) 1994-10-21 1998-06-23 Healthy Foods Solutions, Inc. Reduced-fat compositions and methods for preparing and using same
EP0960567B1 (en) 1995-06-01 2005-10-05 Unilever N.V. Fat based food products
DE69623904T2 (de) 1995-11-02 2003-05-15 Lipidia Holding S.A., Luxemburg/Luxembourg Stabile essbare Ölzusammensetzung
US6139872A (en) 1996-08-14 2000-10-31 Henkel Corporation Method of producing a vitamin product
US6025010A (en) 1997-11-21 2000-02-15 Lipton, Division Of Conopco, Inc. Multifunctional spread
IN185730B (pt) 1998-02-19 2001-04-14 Mcneil Ppc Inc
US6110502A (en) * 1998-02-19 2000-08-29 Mcneil-Ppc, Inc. Method for producing water dispersible sterol formulations
US6025348A (en) 1998-04-30 2000-02-15 Kao Corporation Oil and fat composition containing phytosterol
SE512958C2 (sv) 1998-04-30 2000-06-12 Triple Crown Ab Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning
US6087353A (en) * 1998-05-15 2000-07-11 Forbes Medi-Tech Inc. Phytosterol compositions and use thereof in foods, beverages, pharmaceuticals, nutraceuticals and the like
US5932562A (en) * 1998-05-26 1999-08-03 Washington University Sitostanol formulation to reduce cholesterol absorption and method for preparing and use of same
CA2334449A1 (en) 1998-06-05 1999-12-16 Radka K. Milanova Compositions comprising phytosterol, phytostanol or mixtures of both having enhanced solubility and dispersability and incorporation thereof into foods, beverages, pharmaceuticals, nutraceuticals and the like
US6242001B1 (en) * 1998-11-30 2001-06-05 Mcneil-Ppc, Inc. Method for producing dispersible sterol and stanol compounds

Also Published As

Publication number Publication date
JP2000103737A (ja) 2000-04-11
PT985411E (pt) 2005-02-28
AU764513B2 (en) 2003-08-21
DE69921919T2 (de) 2005-11-24
NO994233D0 (no) 1999-09-01
DK0985411T3 (da) 2005-03-14
CA2281251C (en) 2008-12-30
EP0985411A1 (en) 2000-03-15
AU4585299A (en) 2000-03-16
EP0985411B1 (en) 2004-11-17
CA2281251A1 (en) 2000-03-02
ATE282405T1 (de) 2004-12-15
NO994233L (no) 2000-03-03
NZ337574A (en) 2000-11-24
US20010009677A1 (en) 2001-07-26
US6376481B2 (en) 2002-04-23
DE69921919D1 (de) 2004-12-23

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements