BR9815881A - Uréias e carbamatos de ácido carboxìlicos n-heterocìclicos e isoésteres de ácido carboxìlico - Google Patents
Uréias e carbamatos de ácido carboxìlicos n-heterocìclicos e isoésteres de ácido carboxìlicoInfo
- Publication number
- BR9815881A BR9815881A BR9815881-3A BR9815881A BR9815881A BR 9815881 A BR9815881 A BR 9815881A BR 9815881 A BR9815881 A BR 9815881A BR 9815881 A BR9815881 A BR 9815881A
- Authority
- BR
- Brazil
- Prior art keywords
- isoesters
- carbamates
- carboxylic acid
- heterocyclic
- carboxylic acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/496—Triazoles or their condensed derivatives, e.g. benzotriazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
"URéIAS E CARBAMATOS DE áCIDOS CARBOXìLICOS N-HETEROCìCLICOS E ISOéSTERES DE áCIDO CARBOXìLICO". Esta invenção se refere a novas uréias ou carbamatos de ácidos N-carboxílico heterocíclico e isoésteres de ácido carboxílico, sua preparação e uso para o tratamento de distúrbios neurológicos incluindo nervos danificados fisicamente e doenças neurodegenerativas e para tratamento de alopecia e promoção de crescimento de cabelo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8784498P | 1998-06-03 | 1998-06-03 | |
PCT/US1998/025570 WO1999062879A1 (en) | 1998-06-03 | 1998-12-03 | Ureas and carbamates of n-heterocyclic carboxylic acids and carboxylic acid isosteres |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9815881A true BR9815881A (pt) | 2002-07-23 |
Family
ID=22207585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9815881-3A BR9815881A (pt) | 1998-06-03 | 1998-12-03 | Uréias e carbamatos de ácido carboxìlicos n-heterocìclicos e isoésteres de ácido carboxìlico |
Country Status (17)
Country | Link |
---|---|
US (2) | US20020007075A1 (pt) |
EP (1) | EP1082301A1 (pt) |
JP (1) | JP2002516903A (pt) |
KR (1) | KR20010052502A (pt) |
CN (1) | CN1299346A (pt) |
AU (1) | AU1620499A (pt) |
BG (1) | BG105014A (pt) |
BR (1) | BR9815881A (pt) |
CA (1) | CA2333960A1 (pt) |
EA (1) | EA200001246A1 (pt) |
HU (1) | HUP0102847A2 (pt) |
IL (1) | IL140039A0 (pt) |
NO (1) | NO20006111L (pt) |
PL (1) | PL348671A1 (pt) |
SK (1) | SK18292000A3 (pt) |
WO (1) | WO1999062879A1 (pt) |
ZA (1) | ZA9811061B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000302757A (ja) * | 1999-04-16 | 2000-10-31 | Shiseido Co Ltd | N−置換ピペリジン誘導体 |
BR0012327A (pt) | 1999-07-09 | 2002-07-02 | Ortho Mcneil Pharm Inc | Pirrolidinas e piperidinas neurotróficas, e composições e métodos relacionados |
HU230376B1 (hu) | 2000-10-30 | 2016-03-29 | Janssen Pharmaceutica N.V | Tripeptidil peptidáz inhibitorok |
BR112013017316A2 (pt) | 2011-01-04 | 2019-09-24 | Novartis Ag | compostos de indol ou análogos dos mesmos para o tratamento de degeneração macular relacionada à idade (amd) |
JP6155332B2 (ja) | 2012-06-28 | 2017-06-28 | ノバルティス アーゲー | ピロリジン誘導体、および補体経路調節因子としてのその使用 |
CN104603126B (zh) | 2012-06-28 | 2017-05-31 | 诺华股份有限公司 | 吡咯烷衍生物及其作为补体途径调节剂的用途 |
WO2014002052A1 (en) | 2012-06-28 | 2014-01-03 | Novartis Ag | Pyrrolidine derivatives and their use as complement pathway modulators |
WO2014002058A2 (en) | 2012-06-28 | 2014-01-03 | Novartis Ag | Complement pathway modulators and uses thereof |
ES2710491T3 (es) | 2012-06-28 | 2019-04-25 | Novartis Ag | Moduladores de la vía del complemento y sus usos |
JP6238980B2 (ja) | 2012-07-12 | 2017-11-29 | ノバルティス アーゲー | 補体経路モジュレーターおよびその使用 |
WO2023090853A1 (ko) * | 2021-11-19 | 2023-05-25 | 고려대학교 세종산학협력단 | 신규 우레아계 또는 카바메이트계 p2x7 수용체 길항제 및 이를 유효성분으로 포함하는 주요 우울 장애의 예방 또는 치료용 약학 조성물 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55151555A (en) * | 1979-05-14 | 1980-11-26 | Tanabe Seiyaku Co Ltd | Proline derivatives and their production |
US4402969A (en) * | 1981-03-23 | 1983-09-06 | Merck & Co., Inc. | Antihypertensive proline derivatives |
DE3134933A1 (de) * | 1981-09-03 | 1983-03-31 | Hoechst Ag, 6230 Frankfurt | "harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung" |
JPS58170752A (ja) * | 1982-03-30 | 1983-10-07 | Kureha Chem Ind Co Ltd | N−カルバモイルアミノ酸誘導体 |
DE4228455A1 (de) * | 1992-08-26 | 1994-09-15 | Beiersdorf Ag | Kosmetische und dermatologische Lichtschutzformulierungen mit einem Gehalt an Thiolen und/oder Thiolderivaten |
US5411991A (en) * | 1992-12-22 | 1995-05-02 | Shander; Douglas | Method of reducing hair growth employing sulfhydryl active compounds |
US5264619B1 (en) * | 1993-01-15 | 1996-05-14 | Cosmos Pharm Corp | Anti-androgenic cyclo and bicyclo alkenes |
US5744485A (en) * | 1994-03-25 | 1998-04-28 | Vertex Pharmaceuticals Incorporated | Carbamates and ureas as modifiers of multi-drug resistance |
US5780484A (en) * | 1996-11-13 | 1998-07-14 | Vertex Pharmaceuticals Incorporated | Methods for stimulating neurite growth with piperidine compounds |
US5935989A (en) * | 1996-12-31 | 1999-08-10 | Gpi Nil Holdings Inc. | N-linked ureas and carbamates of heterocyclic thioesters |
-
1998
- 1998-12-03 CN CN98814098A patent/CN1299346A/zh active Pending
- 1998-12-03 SK SK1829-2000A patent/SK18292000A3/sk unknown
- 1998-12-03 IL IL14003998A patent/IL140039A0/xx unknown
- 1998-12-03 PL PL98348671A patent/PL348671A1/xx unknown
- 1998-12-03 WO PCT/US1998/025570 patent/WO1999062879A1/en not_active Application Discontinuation
- 1998-12-03 KR KR1020007013636A patent/KR20010052502A/ko not_active Application Discontinuation
- 1998-12-03 HU HU0102847A patent/HUP0102847A2/hu unknown
- 1998-12-03 EP EP98960656A patent/EP1082301A1/en not_active Withdrawn
- 1998-12-03 JP JP2000552091A patent/JP2002516903A/ja active Pending
- 1998-12-03 CA CA002333960A patent/CA2333960A1/en not_active Abandoned
- 1998-12-03 EA EA200001246A patent/EA200001246A1/ru unknown
- 1998-12-03 AU AU16204/99A patent/AU1620499A/en not_active Abandoned
- 1998-12-03 BR BR9815881-3A patent/BR9815881A/pt not_active Application Discontinuation
- 1998-12-03 ZA ZA9811061A patent/ZA9811061B/xx unknown
-
2000
- 2000-12-01 NO NO20006111A patent/NO20006111L/no not_active Application Discontinuation
- 2000-12-01 BG BG105014A patent/BG105014A/xx unknown
-
2001
- 2001-01-30 US US09/771,686 patent/US20020007075A1/en not_active Abandoned
- 2001-05-03 US US09/847,432 patent/US20020042442A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
IL140039A0 (en) | 2002-02-10 |
JP2002516903A (ja) | 2002-06-11 |
NO20006111L (no) | 2001-02-01 |
SK18292000A3 (sk) | 2001-07-10 |
ZA9811061B (en) | 1999-12-03 |
US20020042442A1 (en) | 2002-04-11 |
HUP0102847A2 (hu) | 2001-12-28 |
WO1999062879A1 (en) | 1999-12-09 |
CN1299346A (zh) | 2001-06-13 |
KR20010052502A (ko) | 2001-06-25 |
US20020007075A1 (en) | 2002-01-17 |
NO20006111D0 (no) | 2000-12-01 |
PL348671A1 (en) | 2002-06-03 |
CA2333960A1 (en) | 1999-12-09 |
EA200001246A1 (ru) | 2001-08-27 |
BG105014A (en) | 2001-08-31 |
AU1620499A (en) | 1999-12-20 |
WO1999062879A8 (en) | 2000-05-04 |
EP1082301A1 (en) | 2001-03-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9815882A (pt) | Sulfonamidas ligadas por n de ácido carboxìlicos n-heterocìclicos ouou de isósteros de ácidos carboxìlicos | |
BR9916461A (pt) | ácidos carboxìlicos e isósteres de ácido carboxìlico de compostos n-heterocìclicos | |
HUP0100815A2 (hu) | Neurológiai és neuropszichiátriai rendellenességek kezelésére szolgáló gyógyszerkészítmények | |
BR9815881A (pt) | Uréias e carbamatos de ácido carboxìlicos n-heterocìclicos e isoésteres de ácido carboxìlico | |
PT1042305E (pt) | Inibicao de quinase p38 utilizando difenilureias simetricas e assimetricas | |
BR9710362A (pt) | Composto formula-ao farmaceutica utiliza-ao de um composto processos de tratamento de um ser humano ou animal sofrendo de uma mediada por atividade anormal de cinase de proteina tirosina e para a prepara-ao de um composto | |
DE69530926D1 (de) | Mittel zur förderung des haarwachstums | |
NO20101190L (no) | Anvendelse av buprenorfin i fremstillingen av et medikament | |
DE69033308T2 (de) | Decahydro-isochinolin-derivate | |
DE69626539D1 (de) | topische Verwendung von Vitamin D zur Behandlung von Augenerkrankungen | |
NO944578L (no) | Eksitatoriske aminosyre reseptor antagonister | |
DE69510928D1 (de) | Heterocyclische verbindungen, ihre herstellung und verwendung | |
DE69824576D1 (de) | Verwendung von tetrahydropyridinderivaten zur herstellung von arzneimitteln zur behandlung demyelinisierender erkrankungen | |
ES2195564T3 (es) | Intermedios novedosos y procedimientos para la preparacion de derivados de acido octanoico opticamente activos. | |
BR9815919A (pt) | Compostos aza heterocìclicos usados para tratar distúrbios neurológicos e perda de cabelo | |
DE69805305D1 (de) | Verwendung von phanquinon zur behandlung von alzheimer's krankheit | |
PT900563E (pt) | Producao de formulacoes farmaceuticas para o tratamento de edema e doencas venosas | |
DE69419954T2 (de) | Arzneimittel zur Behandlung von Hauterkrankungen | |
DE59708511D1 (de) | Verwendung von 7-(1-aminomethyl-2-oxa-7-aza-bicyclo 3.3.0]oct-7-yl)-chinoloncarbonsäure- und -naphthyridoncarbonsäure-derivaten zur therapie von helicobacter-pylori-infektionen und den damit assoziierten gastroduodenalen erkrankungen | |
BR9709930A (pt) | Composto composição farmacêutica uso de um composto e processos para tratamento de um indivíduo humano ou animal e para preparação de um composto | |
DE69900774T2 (de) | Verwendung von topische präparationen mit glyceryl trinitrat und lanolin zur behandlung von erektilen funktionsstörungen | |
SE9904863D0 (sv) | New use | |
PT88242A (pt) | Processo para a preparacao de eteres e tioeteres tendo actividade terapeutica | |
DE69807586D1 (de) | Verwendung eines Alkylendioxybenzolderivats zur Behandlung von zirkadianen Schlafstörungen | |
DE50000562D1 (de) | Mittel zur behandlung von pigmentierungsstörungen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Ipc: C07D 207/16 (2006.01), A61K 8/49 (2006.0 |