BR9815521A - Linhagem única de zymomonas mobilis para fermentação de xilose e de arabinose - Google Patents

Linhagem única de zymomonas mobilis para fermentação de xilose e de arabinose

Info

Publication number
BR9815521A
BR9815521A BR9815521-0A BR9815521A BR9815521A BR 9815521 A BR9815521 A BR 9815521A BR 9815521 A BR9815521 A BR 9815521A BR 9815521 A BR9815521 A BR 9815521A
Authority
BR
Brazil
Prior art keywords
xylose
arabinose
microorganism
zymomonas
zymomonas mobilis
Prior art date
Application number
BR9815521-0A
Other languages
English (en)
Inventor
Min Zhang
Yat-Chen Chou
Stephen K Picataggio
Mark Finkelstein
Original Assignee
Midwest Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Midwest Research Inst filed Critical Midwest Research Inst
Publication of BR9815521A publication Critical patent/BR9815521A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"LINHAGEM úNICA DE ZYMOMONAS MOBILIS PARA FERMENTAçãO DE XILOSE E DE ARABINOSE". Um microorganismo do gênero Zymomonas que contém genes exógenos codificando xilose isomerase, xiluloquinase, L-arabinose isomerase, L-ribuloquinase, L-ribulose-5-fosfato 4-epimerase, transaldolase e transquetolase e compreendendo ainda mais pelo menos um promotor reconhecido por Zymomonas que regula a expressão de pelo menos um dos genes, no qual o microorganismo é capaz de se desenvolver tendo arabinose e xilose como fontes de carbono e de fermentar a arabinose e xilose em etanol com um rendimento teórico de aproximadamente 75% e no qual o microorganismo sem os genes é incapaz de se desenvolver em ou de fermentar arabinose e xilose em etanol.
BR9815521-0A 1997-05-06 1998-04-05 Linhagem única de zymomonas mobilis para fermentação de xilose e de arabinose BR9815521A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/851,767 US5843760A (en) 1994-04-15 1997-05-06 Single zymomonas mobilis strain for xylose and arabinose fermentation
PCT/US1998/009171 WO1998050524A1 (en) 1997-05-06 1998-04-05 Single zymomonas mobilis strain for xylose and arabinose fermentation

Publications (1)

Publication Number Publication Date
BR9815521A true BR9815521A (pt) 2003-01-07

Family

ID=25311631

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9815521-0A BR9815521A (pt) 1997-05-06 1998-04-05 Linhagem única de zymomonas mobilis para fermentação de xilose e de arabinose

Country Status (8)

Country Link
US (1) US5843760A (pt)
EP (1) EP1005530B1 (pt)
AU (1) AU7176898A (pt)
BR (1) BR9815521A (pt)
CA (1) CA2289091C (pt)
DE (1) DE69833852T2 (pt)
DK (1) DK1005530T3 (pt)
WO (1) WO1998050524A1 (pt)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000071738A1 (en) * 1999-05-21 2000-11-30 Cargill Dow Llc Methods and materials for the synthesis of organic products
US7354755B2 (en) 2000-05-01 2008-04-08 Midwest Research Institute Stable zymomonas mobilis xylose and arabinose fermenting strains
US7223575B2 (en) * 2000-05-01 2007-05-29 Midwest Research Institute Zymomonas pentose-sugar fermenting strains and uses thereof
US7374939B1 (en) 2000-05-01 2008-05-20 Midwest Research Institute Method of inactivation of an end product of energy metabolism in Zymomonas mobilis
BR0110987B1 (pt) * 2000-05-01 2014-07-15 Alliance Sustainable Energy Transposon para inserção estável de genes alheios dentro de um genoma bacteriano, vetor plasmídio, bactéria, e, mistura de reação compreendendo um meio fermentável
US6566107B1 (en) * 2000-11-01 2003-05-20 Midwest Research Institute Recombinant Zymomonas mobilis with improved xylose utilization
FI20010308A0 (fi) 2001-02-16 2001-02-16 Valtion Teknillinen Sienen käsitteleminen geneettisesti siten, että se pystyy käyttämään L-arabinoosia
CA2473355C (en) * 2002-01-18 2012-01-03 Michael E. Snyder Sustained release ophthalmological device and method of making and using the same
SE0202090D0 (sv) * 2002-05-08 2002-07-04 Forskarpatent I Syd Ab A modifierd yeast consuming L-arabinose
FI116068B (fi) * 2003-09-15 2005-09-15 Fit Biotech Oyj Plc Uusi selektiojärjestelmä, siinä käyttökelpoinen vektori, bakteerisolukantoja sekä menetelmä solujen valikoimiseksi
WO2005065354A2 (en) * 2003-12-31 2005-07-21 The Burnham Institute Defined media for pluripotent stem cell culture
US8003367B2 (en) * 2004-03-16 2011-08-23 Ajinomoto Co., Inc. Method for producing L-amino acids by fermentation using bacteria having enhanced expression of xylose utilization genes
US7666637B2 (en) * 2006-09-05 2010-02-23 Xuan Nghinh Nguyen Integrated process for separation of lignocellulosic components to fermentable sugars for production of ethanol and chemicals
US7741084B2 (en) 2006-09-28 2010-06-22 E. I. Du Pont De Nemours And Company Ethanol production using xylitol synthesis mutant of xylose-utilizing zymomonas
US7741119B2 (en) * 2006-09-28 2010-06-22 E. I. Du Pont De Nemours And Company Xylitol synthesis mutant of xylose-utilizing zymomonas for ethanol production
US7629156B2 (en) 2006-09-28 2009-12-08 E.I. Du Pont De Nemours And Company Ethanol production in fermentation of mixed sugars containing xylose
GB0620715D0 (en) 2006-10-18 2006-11-29 Univ Durham Ethanol production
DE102007016534B4 (de) * 2007-04-05 2019-03-28 Butalco Gmbh Neuer Expressionsvektor von Codon-optimierten Genen eines Arabinose-Stoffwechselweges zur Arabinose-Umsetzung in Hefe
GB2449306A (en) * 2007-05-18 2008-11-19 Univ Sheffield Composite particles
JP4124270B1 (ja) * 2007-10-05 2008-07-23 国立大学法人鳥取大学 グルコース・マンノース・キシロース並行発酵性菌およびそれを用いるバイオエタノールの製造方法
ES2385857T3 (es) * 2007-10-30 2012-08-01 E. I. Du Pont De Nemours And Company Zymomonas con producción aumentada de etanol en medio que contiene azúcares concentrados y acetato
JP2011515067A (ja) * 2007-10-30 2011-05-19 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー ｈｉｍＡ発現の減少した組み換えザイモモナス株を使用する、キシロースを含む培地からエタノールを産生する方法
US8915644B2 (en) 2008-07-24 2014-12-23 Abengoa Bioenergy New Technologies, Llc. Method and apparatus for conveying a cellulosic feedstock
CA2650913C (en) 2009-01-23 2013-10-15 Sunopta Bioprocess Inc. Method and apparatus for conveying a cellulosic feedstock
CA2638159C (en) 2008-07-24 2012-09-11 Sunopta Bioprocess Inc. Method and apparatus for treating a cellulosic feedstock
US9127325B2 (en) 2008-07-24 2015-09-08 Abengoa Bioenergy New Technologies, Llc. Method and apparatus for treating a cellulosic feedstock
CA2638157C (en) 2008-07-24 2013-05-28 Sunopta Bioprocess Inc. Method and apparatus for conveying a cellulosic feedstock
CA2638160C (en) 2008-07-24 2015-02-17 Sunopta Bioprocess Inc. Method and apparatus for conveying a cellulosic feedstock
CA2650919C (en) 2009-01-23 2014-04-22 Sunopta Bioprocess Inc. Method and apparatus for conveying a cellulosic feedstock
CA2638150C (en) 2008-07-24 2012-03-27 Sunopta Bioprocess Inc. Method and apparatus for conveying a cellulosic feedstock
WO2010014817A2 (en) * 2008-07-30 2010-02-04 Novozymes A/S Producing fermentation products
US8247208B2 (en) 2008-12-22 2012-08-21 Alliance For Sustainable Energy Llc Zymomonas with improved xylose utilization in stress conditions
US20100291647A1 (en) 2009-04-29 2010-11-18 Ut-Battelle, Llc Microorganisms Having Enhanced Resistance To Acetate And Related Compositions And Methods of Use
US20100311137A1 (en) * 2009-06-08 2010-12-09 Ut-Battelle, Llc Microorganisms Having Enhanced Tolerance To Inhibitors and Stress
US20110143408A1 (en) * 2009-06-18 2011-06-16 E. I. Du Pont De Nemours And Company Zymomonas with improved arabinose utilization
WO2011006126A2 (en) * 2009-07-09 2011-01-13 Verdezyne, Inc Engineered microorganisms with enhanced fermentation activity
CA2755981C (en) 2009-08-24 2015-11-03 Abengoa Bioenergy New Technologies, Inc. Method for producing ethanol and co-products from cellulosic biomass
US8785159B2 (en) * 2009-11-25 2014-07-22 Alliance For Sustainable Energy, Llc Extracellular secretion of recombinant proteins
US8679822B2 (en) 2010-06-29 2014-03-25 E I Du Pont De Nemours And Company Xylose utilization in recombinant zymomonas
US8623623B2 (en) 2010-06-29 2014-01-07 E I Du Pont De Nemours And Company Xylose utilization in recombinant Zymomonas
US8476048B2 (en) 2010-12-17 2013-07-02 E I Du Pont De Nemours And Company Xylose utilizing zymomonas mobilis with improved ethanol production in biomass hydrolysate medium
US20140141473A1 (en) * 2011-04-22 2014-05-22 Dsm Ip Assets B.V. Yeast cell capable of converting sugars including arabinose and xlose
US20130157332A1 (en) 2011-12-20 2013-06-20 E I Du Pont De Nemours And Company Gene inactivation allowing immediate growth on xylose medium by engineered zymomonas
US8911983B2 (en) 2011-12-20 2014-12-16 E I Du Pont De Nemours And Company Pnp gene modification for improved xylose utilization in Zymomonas
US8697426B2 (en) 2012-06-15 2014-04-15 E I Du Pont De Nemours And Company Contaminant control in Zymomonas fermentation using virginiamycin
US8759069B2 (en) 2012-06-15 2014-06-24 E I Du Pont De Nemours And Company Contaminant control in Zymomonas fermentation using hop acids
US8846357B2 (en) 2012-12-20 2014-09-30 E I Du Pont De Nemours And Company Stabilized chlorine dioxide for contamination control in Zymomonas fermentation
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
US9206445B2 (en) 2013-04-29 2015-12-08 Alliance For Sustainable Energy, Llc Biocatalysts with enhanced inhibitor tolerance
JP6344388B2 (ja) * 2013-07-02 2018-06-20 三菱ケミカル株式会社 糖液の処理方法、水素化処理糖液、有機化合物の製造方法および微生物の培養方法
US20150087040A1 (en) 2013-09-26 2015-03-26 E I Du Pont De Nemours And Company Production of ethanol and recycle water in a cellulosic fermentation process
US9139818B2 (en) 2013-09-26 2015-09-22 E I Du Pont De Nemours And Company High expression Zymomonas promoters
US20150087041A1 (en) 2013-09-26 2015-03-26 E I Du Pont De Nemours And Company Production of ethanol with reduced contaminants in a cellulosic biomass based process
US20150147786A1 (en) 2013-11-24 2015-05-28 E I Du Pont De Nemours And Company High force and high stress destructuring for starch biomass processing
US9371546B2 (en) 2014-06-24 2016-06-21 E I Du Pont De Nemours And Company Enhancing D-xylose and L-arabinose utilization in Zymomonas cells
WO2016109286A1 (en) 2014-12-31 2016-07-07 Indiana University Research & Technology Corporation Culture conditions that allow zymomonas mobilis to assimilate n2 gas as a nitrogen source during bio-ethanol production
KR102676949B1 (ko) 2015-07-13 2024-06-19 마라 리뉴어블즈 코퍼레이션 크실로오스의 미세조류 대사를 강화시키는 방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4731329A (en) * 1980-09-05 1988-03-15 George Weston Ltd. Ethanol production by high performance bacterial fermentation
AT385282B (de) * 1984-10-18 1988-03-10 Vogelbusch Gmbh Verfahren zur kontinuierlichen herstellung von aethanol
US4816399A (en) * 1985-04-12 1989-03-28 George Weston Limited Continuous process for ethanol production by bacterial fermentation
US4812410A (en) * 1985-04-12 1989-03-14 George Weston Limited Continuous process for ethanol production by bacterial fermentation
US5041378A (en) * 1987-08-11 1991-08-20 Cetus Corporation Procaryotic xylose isomerase muteins
US5000000A (en) * 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
US5028539A (en) * 1988-08-31 1991-07-02 The University Of Florida Ethanol production using engineered mutant E. coli
US5168056A (en) * 1991-02-08 1992-12-01 Purdue Research Foundation Enhanced production of common aromatic pathway compounds
US5266475A (en) * 1991-09-19 1993-11-30 Michigan Biotechnology Institute Glucose isomerases with improved affinity for D-glucose
US5272073A (en) * 1992-06-30 1993-12-21 Purdue Research Foundation Biocatalytic synthesis of catechol from glucose
US5712133A (en) * 1994-04-15 1998-01-27 Midwest Research Institute Pentose fermentation by recombinant zymomonas
WO1995028476A1 (en) * 1994-04-15 1995-10-26 Midwest Research Institute Recombinant zymomonas for pentose fermentation

Also Published As

Publication number Publication date
AU7176898A (en) 1998-11-27
EP1005530A4 (en) 2002-07-31
EP1005530B1 (en) 2006-03-15
CA2289091C (en) 2010-10-19
EP1005530A1 (en) 2000-06-07
DE69833852D1 (de) 2006-05-11
CA2289091A1 (en) 1998-11-12
DE69833852T2 (de) 2007-10-18
US5843760A (en) 1998-12-01
DK1005530T3 (da) 2006-07-03
WO1998050524A1 (en) 1998-11-12

Similar Documents

Publication Publication Date Title
BR9815521A (pt) Linhagem única de zymomonas mobilis para fermentação de xilose e de arabinose
Ibrahim et al. Cellulosic biobutanol by Clostridia: Challenges and improvements
Gutiérrez‐Rivera et al. Conversion efficiency of glucose/xylose mixtures for ethanol production using Saccharomyces cerevisiae ITV01 and Pichia stipitis NRRL Y‐7124
Agbogbo et al. Cellulosic ethanol production using the naturally occurring xylose-fermenting yeast, Pichia stipitis
Jeffries Engineering yeasts for xylose metabolism
Long et al. Cofermentation of glucose, xylose, and cellobiose by the beetle-associated yeast Spathaspora passalidarum
Yomano et al. Deletion of methylglyoxal synthase gene (mgsA) increased sugar co-metabolism in ethanol-producing Escherichia coli
Hector et al. Saccharomyces cerevisiae engineered for xylose metabolism requires gluconeogenesis and the oxidative branch of the pentose phosphate pathway for aerobic xylose assimilation
BRPI0409954A (pt) espécies leveduras geneticamente modificados e processos de fermentação utilizando levedura geneticamente modificada
DE69434291D1 (de) Rekombinante hefe zur effizienten fermentation von glucose und xylose
BR0309796A (pt) Linhagens de zymomonas de fermentação de açúcar pentose e usos das mesmas, processo, método, integrante de zymomonas e biocatalisador
DE69832624D1 (de) Hefestämme zur herstellung von milchsäure
Jayakody et al. Engineering redox cofactor utilization for detoxification of glycolaldehyde, a key inhibitor of bioethanol production, in yeast Saccharomyces cerevisiae
CA2146920A1 (en) Carbonate Fuel Cell with Direct Recycle of Anode Exhaust to Cathode
ES2292585T3 (es) Levadura recombinante para materias primas lignocelulosicas.
SE8302654D0 (sv) A method for producing ethanol from xylose-containing substance
BR0308507A (pt) Engenharia metabólica para a utilização de xilose aperfeiçoada de saccharomyces cerevisiae
Liu et al. gTME for improved xylose fermentation of Saccharomyces cerevisiae
ES2133612T3 (es) Metodo de recuperar energia de residuos solidos.
Castañón‐Rodríguez et al. Continuous multistep versus fed‐batch production of ethanol and xylitol in a simulated medium of sugarcane bagasse hydrolyzates
Kihara et al. Highly efficient continuous acetone–butanol–ethanol production from mixed sugars without carbon catabolite repression
González-Peñas et al. Organosolv pretreated beech wood as a substrate for acetone butanol ethanol extractive fermentation
Kocher et al. Fermentation variables for the fermentation of glucose and xylose using Saccharomyces cerevisiae Y-2034 and Pachysolan tannophilus Y-2460
US11319556B2 (en) Yeast strain with glucose and xylose co-utilization capacity
Gottsater et al. Islet cell antibodies and fasting plasma C-peptide during the first 10 yr after diagnosis in patients with diabetes mellitus diagnosed in adult age

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 37, INDEFIRO O PRESENTE PEDIDO, TENDO POR BASE O ARTIGO 8O COMBINADO COM O ARTIGO 13 DA LPI 9279 DE 14/05/1996.

B12B Appeal against refusal [chapter 12.2 patent gazette]