DE69832624D1 - Hefestämme zur herstellung von milchsäure - Google Patents

Hefestämme zur herstellung von milchsäure

Info

Publication number
DE69832624D1
DE69832624D1 DE69832624T DE69832624T DE69832624D1 DE 69832624 D1 DE69832624 D1 DE 69832624D1 DE 69832624 T DE69832624 T DE 69832624T DE 69832624 T DE69832624 T DE 69832624T DE 69832624 D1 DE69832624 D1 DE 69832624D1
Authority
DE
Germany
Prior art keywords
hefestamms
preparation
milky acid
acid
milky
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69832624T
Other languages
English (en)
Other versions
DE69832624T2 (de
Inventor
Danilo Porro
Michele Bianchi
Maria Ranzi
Laura Frontali
Marina Vai
Adrian Winkler
Lilia Alberghina
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Primary Products Ingredients Americas LLC
Original Assignee
Tate and Lyle Ingredients Americas LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tate and Lyle Ingredients Americas LLC filed Critical Tate and Lyle Ingredients Americas LLC
Application granted granted Critical
Publication of DE69832624D1 publication Critical patent/DE69832624D1/de
Publication of DE69832624T2 publication Critical patent/DE69832624T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Alcoholic Beverages (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69832624T 1997-09-12 1998-09-11 Hefestämme zur herstellung von milchsäure Expired - Fee Related DE69832624T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT97MI002080A IT1294728B1 (it) 1997-09-12 1997-09-12 Ceppi di lievito per la riproduzione di acido lattico
ITMI972080 1997-09-12
PCT/EP1998/005758 WO1999014335A1 (en) 1997-09-12 1998-09-11 Yeast strains for the production of lactic acid

Publications (2)

Publication Number Publication Date
DE69832624D1 true DE69832624D1 (de) 2006-01-05
DE69832624T2 DE69832624T2 (de) 2006-06-08

Family

ID=11377865

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832624T Expired - Fee Related DE69832624T2 (de) 1997-09-12 1998-09-11 Hefestämme zur herstellung von milchsäure

Country Status (13)

Country Link
US (3) US6429006B1 (de)
EP (1) EP1012298B1 (de)
JP (1) JP2001516584A (de)
AT (1) ATE311460T1 (de)
AU (1) AU748462B2 (de)
BR (1) BR9812434A (de)
CA (1) CA2302434A1 (de)
DE (1) DE69832624T2 (de)
DK (1) DK1012298T3 (de)
ES (1) ES2252863T3 (de)
IT (1) IT1294728B1 (de)
SI (1) SI1012298T1 (de)
WO (1) WO1999014335A1 (de)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294728B1 (it) * 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US20070031950A1 (en) * 1998-09-11 2007-02-08 Winkler Aaron A Production of D-lactic acid with yeast
KR20020048910A (ko) * 1999-05-21 2002-06-24 카길 다우 엘엘씨 유기 생성물의 합성방법 및 재료
AUPQ137699A0 (en) * 1999-07-02 1999-07-22 University Of New England, The Control of acidosis
US6268189B1 (en) 2000-03-24 2001-07-31 The United States Of America As Represented By The Secretary Of Agriculture Fungal lactate dehydrogenase gene and constructs for the expression thereof
JP2002136293A (ja) * 2000-08-23 2002-05-14 Toray Ind Inc 微生物およびｄ−乳酸の製造方法
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
CN1571838B (zh) * 2001-09-20 2010-05-26 丰田自动车株式会社 实现基因高表达的系统
JP2003093060A (ja) * 2001-09-20 2003-04-02 Toyota Motor Corp 耐酸性微生物を用いた有機酸及びアルコールの製造方法
JP2003259878A (ja) * 2002-03-11 2003-09-16 Toyota Central Res & Dev Lab Inc 乳酸脱水素酵素をコードするｄｎａおよびその利用
CN100526466C (zh) * 2002-03-11 2009-08-12 丰田自动车株式会社 控制乙醇产生的方法
AU2003243366B2 (en) * 2002-05-30 2008-01-24 Natureworks Llc Methods and materials for the production of lactic acid in yeast
GB0222185D0 (en) * 2002-09-24 2002-10-30 Forinnova As Use
WO2004065552A2 (en) * 2003-01-21 2004-08-05 Duke University Cell-based therapies for diabetes mellitus and other glucose intolerant states
US20050014692A1 (en) * 2003-01-21 2005-01-20 Newgard Christopher B. Lactate dehydrogenase as a novel target and reagent for diabetes therapy
ES2543385T3 (es) 2003-05-02 2015-08-18 Cargill, Incorporated Especies de levadura genéticamente modificadas y procesos de fermentación que emplean levaduras genéticamente modificadas
CN1795270B (zh) * 2003-05-22 2011-09-21 丰田自动车株式会社 编码具有d-乳酸脱氢酶活性蛋白质的dna及其用途
JP4460876B2 (ja) * 2003-11-07 2010-05-12 株式会社豊田中央研究所 有機酸存在下におけるプロモーター及びその利用
US20050112737A1 (en) * 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
BRPI0509301B1 (pt) 2004-03-31 2017-04-11 Natureworks Llc processo para fermentação de açucares contendo sacarídeos oligoméricos
JP2006006271A (ja) * 2004-06-29 2006-01-12 Toyota Central Res & Dev Lab Inc 乳酸生産酵母および乳酸生産方法
JP4806904B2 (ja) * 2004-07-09 2011-11-02 トヨタ自動車株式会社 乳酸生産方法
US20060234360A1 (en) * 2005-04-13 2006-10-19 Paola Branduardi Ascorbic acid production from D-glucose in yeast
KR20080028902A (ko) * 2005-06-02 2008-04-02 카아길, 인코포레이팃드 이싸첸키아 오리엔탈리스에 속하는 종 및 그와 밀접한관련이 있는 종의 유전자 변형된 효모 및 이를 이용한 발효방법
PL2305826T3 (pl) 2005-08-10 2016-10-31 Materiały i sposoby do wydajnej produkcji kwasu mlekowego
EP1929009A2 (de) * 2005-09-22 2008-06-11 Tate & Lyle Ingredients Americas, Inc. Verbesserte stämme zur herstellung organischer säuren
US8071357B2 (en) * 2005-10-14 2011-12-06 Toray Industries, Inc. Yeast and method of producing L-lactic acid
BRPI0618937A2 (pt) * 2005-11-23 2011-09-13 Natureworks Llc células de levedura que produzem ácido lático tendo l-ou d-lactato não funcional: gene de ferricitocromo c oxidoredutase
PL2586313T3 (pl) 2006-03-13 2017-06-30 Cargill, Incorporated Sposób fermentacji przy użyciu komórek drożdży mających zaburzony szlak od fosforanu dihydroksyacetonu do glicerolu
JP5320692B2 (ja) * 2006-06-28 2013-10-23 東レ株式会社 酵母及びｌ−乳酸の製造方法
US20100291648A1 (en) 2006-12-07 2010-11-18 Massachusetts Institute Of Technology Global transcription machinery engineering
US20100062505A1 (en) * 2006-12-21 2010-03-11 Gevo, Inc. Butanol production by metabolically engineered yeast
JP2010115112A (ja) * 2007-02-28 2010-05-27 Neo-Morgan Laboratory Inc 酵母の製造方法，酵母，及び乳酸の製造方法
EP2158323A4 (de) * 2007-05-18 2011-06-22 Microbia Prec Engineering Inc Produktion organischer säure durch pilzzellen
JP2008283917A (ja) * 2007-05-18 2008-11-27 Toray Ind Inc 乳酸の製造方法
KR20100094525A (ko) * 2007-12-07 2010-08-26 도레이 카부시키가이샤 락트산 탈수소효소 발현 카세트, 형질전환 효모 및 락트산의 제조방법
EP2231857A2 (de) 2007-12-17 2010-09-29 Universiteit van Amsterdam Lichtgesteuerte CO2-Reduktion in organischen Verbindungen, die als Brennstoffe oder industrielle Halbzeuge dienen, durch ein autotrophes Element mit einer fermentativen Genkassette
US8455239B2 (en) 2007-12-23 2013-06-04 Gevo, Inc. Yeast organism producing isobutanol at a high yield
CA2990939A1 (en) 2007-12-23 2009-07-09 Gevo, Inc. Yeast organism producing isobutanol at a high yield
MY153731A (en) 2007-12-27 2015-03-13 Gevo Inc Recovery of higher alcohols from dilute aqueous solutions
KR101483470B1 (ko) * 2008-02-04 2015-01-16 도레이 카부시키가이샤 연속 발효에 의한 유산의 제조방법
EP2706111A1 (de) * 2008-03-03 2014-03-12 Joule Unlimited Technologies, Inc. Manipulierte CO2-fixierende Mikroorganismen zur Herstellung kohlenstoffbasierter Produkte von Interesse
US8048654B2 (en) 2010-06-09 2011-11-01 Joule Unlimited Technologies, Inc. Methods and compositions for the recombinant biosynthesis of fatty acids and esters
JP4963488B2 (ja) * 2008-04-23 2012-06-27 トヨタ自動車株式会社 変異体酵母及びこれを用いた物質生産方法
EP2128262A1 (de) * 2008-05-28 2009-12-02 Università Degli Studi Di Milano - Bicocca Verbesserte Hefestämme zur Herstellung organischer Säure
EP2316961A4 (de) * 2008-06-30 2012-04-25 Toyota Motor Co Ltd Verfahren zur herstellung organischer säure
ES2560281T3 (es) 2008-10-17 2016-02-18 Joule Unlimited Technologies, Inc. Producción de etanol por microorganismos
EP2239333A1 (de) 2009-04-07 2010-10-13 Sanovations B.V. Verfahren zur Gewinnung von organischen Säuren aus wässrigen Lösungen, die aus bioorganischen Materialien erhalten werden
EP3865569B1 (de) * 2009-04-30 2023-10-04 Genomatica, Inc. Organismen zur herstellung von 1,3-butandiol
US20110020867A1 (en) * 2009-07-20 2011-01-27 Joule Unlimited, Inc. Constructs And Methods For Efficient Transformation Of Micro-Organisms For Production Of Carbon-Based Products Of Interest
IN2012DN01521A (de) * 2009-08-21 2015-06-05 Asahi Glass Co Ltd
EP2719757A1 (de) 2009-09-04 2014-04-16 President and Fellows of Harvard College Herstellung sekretierter bioprodukte aus photosynthese-mikroben
EP3287519B1 (de) 2010-11-22 2020-03-18 Cargill, Incorporated Zusammensetzungen und verfahren zur herstellung von 3-hydroxypropionsäure
BR112013012130A2 (pt) 2010-11-22 2017-10-31 Cargill Inc composições e métodos para titulação aumentada de etanol a partir de biomassa
CA2825525A1 (en) 2011-01-25 2012-08-02 Jeanette M. HURYTA Compositions and methods for succinate production
CA2832587A1 (en) 2011-04-11 2012-10-18 Cargill, Incorporated Compositions and methods for increased ethanol production from biomass
US9217165B2 (en) 2011-04-28 2015-12-22 Toray Industries, Inc. Mutant strain of lactic acid producing yeast and process for producing lactic acid
CN102816706B (zh) * 2011-05-12 2013-08-21 江南大学 中国酱香型白酒生产中高产乙醇低产杂醇油的酵母cgmcc 4745的筛选与应用
FR2988733B1 (fr) * 2012-03-27 2016-02-05 Carbios Microorganisme recombinant
BR112015001601A2 (pt) 2012-07-25 2017-11-07 Bioamber Sas células de levedura tendo curso de tca redutor de piruvato em succinato e superexpressão de uma enzima transidrogenase nad(p)+ exógena
CN104812889B (zh) 2012-09-14 2018-08-28 麦兰特公司 通过在低ph下发酵产生有机酸
WO2014085330A1 (en) 2012-11-30 2014-06-05 Novozymes, Inc. 3-hydroxypropionic acid production by recombinant yeasts
US20150315615A1 (en) 2012-12-10 2015-11-05 Cargill, Incorporated Batch feed process for fermenting sugars
US9222110B2 (en) 2012-12-17 2015-12-29 South Dakota Board Of Regents Microorganism and method for lactic acid production
JP2014150800A (ja) * 2013-02-05 2014-08-25 Samsung Electronics Co Ltd 乳酸トランスポーターを高レベルに発現させる乳酸生産微生物、及びそれを利用した乳酸生産方法
BR112016001778A2 (pt) 2013-07-31 2017-09-05 Novozymes As Célula transgênica de levedura, composição, e, métodos de produção de 3-hp e de produção de ácido acrílico ou um sal do mesmo
KR20150034867A (ko) * 2013-09-25 2015-04-06 삼성전자주식회사 세포질 내 피루베이트 풀이 강화된 효모 및 이를 이용한 피루베이트 기반 대사산물을 생산하는 방법
US9593350B2 (en) 2014-02-14 2017-03-14 Samsung Electronics Co., Ltd. Lactate dehydrogenase mutant, polynucleotide coding for the mutant, yeast cell including the polynucleotide, method of preparing the mutant, and method of producing the lactate using the same
KR101577134B1 (ko) * 2014-05-09 2015-12-14 씨제이제일제당 (주) 젖산 생산이 향상된 미생물 및 이를 이용하여 젖산을 생산하는 방법
ES2924896T3 (es) 2014-05-16 2022-10-11 Carbios Procedimiento para reciclar artículos de plástico mixto con PET
KR102227975B1 (ko) * 2014-07-24 2021-03-15 삼성전자주식회사 방사선 감수성 보완 키나아제의 활성이 증가되도록 유전적으로 조작된, 내산성을 갖는 효모 세포 및 그를 이용하여 락테이트를 생산하는 방법
KR102245298B1 (ko) * 2014-09-05 2021-04-27 삼성전자주식회사 증가된 edc 활성을 갖고 락테이트 생산능을 갖는 유전적으로 조작된 효모 세포, 그를 제조하는 방법, 그를 제조하는 방법, 및 그를 사용하여 락테이트를 생산하는 방법
CN113667659A (zh) 2014-10-21 2021-11-19 卡比欧斯公司 具有聚酯降解活性的多肽及其用途
US10626242B2 (en) 2014-12-19 2020-04-21 Carbios Plastic compound and preparation process
WO2016146540A1 (en) 2015-03-13 2016-09-22 Carbios New polypeptide having a polyester degrading activity and uses thereof
CN107429220A (zh) 2015-03-27 2017-12-01 嘉吉公司 经葡糖淀粉酶修饰的酵母菌株和用于产生生物产物的方法
CA2985231A1 (en) 2015-06-04 2016-12-08 Bioamber Inc. Biobased production of functionalized alpha-substituted acrylates and c4-dicarboxylates
US10155967B2 (en) 2015-06-12 2018-12-18 Cj Cheiljedang Corporation Microorganism having enhanced productivity of lactic acid and a process for producing lactic acid using the same
US11198767B2 (en) 2015-06-12 2021-12-14 Carbios Process for preparing a biodegradable plastic composition
EP3332004A1 (de) 2015-08-05 2018-06-13 Cargill, Incorporated Xyloseisomerasemodifizierte hefestämme und verfahren zur bioproduktherstellung
WO2017091614A1 (en) 2015-11-24 2017-06-01 Cargill Incorporated Genetically modified yeasts and fermentation processes using genetically modified yeasts
EP3394264A1 (de) 2015-12-21 2018-10-31 Carbios Polymilchsäure produzierende rekombinante hefezellen und verwendungen davon
MX2018012297A (es) * 2016-04-18 2019-11-21 Syconium Lactic Acid Gmbh Metodo para la produccion de acido lactico.
EP3458508A1 (de) 2016-05-19 2019-03-27 Carbios Verfahren zum abbau von kunststoffprodukten
WO2018027131A1 (en) 2016-08-05 2018-02-08 Cargill, Incorporated Leader-modified glucoamylase polypeptides and engineered yeast strains having enhanced bioproduct production
US11718820B2 (en) 2017-08-17 2023-08-08 Cargill, Incorporated Genetically modified haploid Issatchenkia orientalis
WO2019159011A2 (en) 2018-02-16 2019-08-22 Ptt Global Chemical Public Company Limited Microorganisms and processes for lactic acid production
KR102140597B1 (ko) * 2018-04-17 2020-08-03 에스케이이노베이션 주식회사 에탄올 생산 경로가 억제된 내산성 효모 및 이를 이용한 젖산의 제조방법
KR102140596B1 (ko) 2018-04-17 2020-08-04 에스케이이노베이션 주식회사 유기산 내성 효모 유래 신규 프로모터 및 이를 이용한 목적유전자의 발현방법
KR20200040017A (ko) * 2018-10-08 2020-04-17 에스케이이노베이션 주식회사 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210041903A (ko) 2019-10-08 2021-04-16 에스케이이노베이션 주식회사 락테이트 대사 및 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210158676A (ko) 2020-06-24 2021-12-31 에스케이이노베이션 주식회사 젖산 생산능이 증가된 재조합 내산성 효모

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2024565A (en) 1931-10-29 1935-12-17 Standard Brands Inc Process for the production of lactic acid
JPH0740945B2 (ja) * 1987-04-15 1995-05-10 東レ株式会社 発酵法によるピルビン酸の製造法
US4885247A (en) 1988-04-19 1989-12-05 Michigan Biotechnology Institute Recovery and purification of lactate salts from whole fermentation broth by electrodialysis
US5068418A (en) 1989-05-08 1991-11-26 Uop Separation of lactic acid from fermentation broth with an anionic polymeric absorbent
US5464760A (en) 1990-04-04 1995-11-07 University Of Chicago Fermentation and recovery process for lactic acid production
TW211560B (de) 1991-03-14 1993-08-21 Peilly Ind Inc
FR2692591B1 (fr) * 1992-06-23 1995-06-09 Agronomique Inst Nat Rech Souches de levure exprimant le gene de la ldh lactique, et vecteurs utilisables pour l'obtention desdites souches.
FR2693463B1 (fr) 1992-07-08 1994-09-02 Rhone Poulenc Rorer Sa Promoteur de levure et son utilisation.
AT398982B (de) 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US6187951B1 (en) 1993-06-29 2001-02-13 Cargill, Incorporated Lactic acid production, separation and/or recovery process
US5510526A (en) 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
US6001255A (en) 1993-07-12 1999-12-14 Eyal; Aharon Process for the production of water-soluble salts of carboxylic and amino acids
US5503750A (en) 1993-10-04 1996-04-02 Russo, Jr.; Lawrence J. Membrane-based process for the recovery of lactic acid by fermentation of carbohydrate substrates containing sugars
US5573180A (en) * 1995-08-03 1996-11-12 Carrier Corporation Protective thermostat
DE19544233A1 (de) 1995-11-28 1997-06-05 Hoechst Ag Verfahren zur Nutzung des Hefe-ADH II-Promotorsystems zur biotechnologischen Produktion heterologer Proteine in hohen Ausbeuten
IL119389A (en) 1996-10-09 2001-10-31 Cargill Inc Process for the recovery of lactic acid by liquid-liquid extraction using a cation exchanger
US6160173A (en) 1996-10-09 2000-12-12 Cargill Incorporated Process for the recovery of lactic acid esters and amides from aqueous solutions of lactic acid and/or salts thereof
WO1998028433A1 (en) 1996-12-23 1998-07-02 Lactascan Aps Fermentative production and isolation of lactic acid
BE1011197A3 (fr) 1997-06-06 1999-06-01 Brussels Biotech En Abrege Bb Procede de purification d'acide lactique.
IL121207A (en) 1997-06-30 2000-10-31 Staley Mfg Co A E Liquid-liquid extraction for the recovery of lactic acid with an amine solution in the presence of carbon dioxide
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US6475759B1 (en) 1997-10-14 2002-11-05 Cargill, Inc. Low PH lactic acid fermentation
US6229046B1 (en) 1997-10-14 2001-05-08 Cargill, Incorported Lactic acid processing methods arrangements and products
US6043072A (en) 1998-11-05 2000-03-28 Washington State University Research Foundation Nucleic acids encoding Taxus geranylgeranyl diphosphate synthase, and methods of use
KR20020048910A (ko) 1999-05-21 2002-06-24 카길 다우 엘엘씨 유기 생성물의 합성방법 및 재료
US20020102672A1 (en) 1999-10-04 2002-08-01 Joseph Mizrahi Process for producing a purified lactic acid solution
FR2799754A1 (fr) 1999-10-18 2001-04-20 Roquette Freres Procede de separation et de purification d'acide lactique a partir d'un milieu de fermentation
US6268189B1 (en) 2000-03-24 2001-07-31 The United States Of America As Represented By The Secretary Of Agriculture Fungal lactate dehydrogenase gene and constructs for the expression thereof
US7141410B2 (en) 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
US7109010B2 (en) 2000-11-22 2006-09-19 Nature Works Llc Methods and materials for the synthesis of organic products
JP4450621B2 (ja) 2001-08-24 2010-04-14 プラク・ビオヘム・ベー・ブイ 乳酸および硫酸カルシウム二水和物の製法
WO2003049525A2 (en) 2001-11-23 2003-06-19 Cargill Dow Llc Methods and materials for the production of organic products in cells of $i(candida) species
JP2003259878A (ja) 2002-03-11 2003-09-16 Toyota Central Res & Dev Lab Inc 乳酸脱水素酵素をコードするｄｎａおよびその利用
CN100526466C (zh) 2002-03-11 2009-08-12 丰田自动车株式会社 控制乙醇产生的方法
BRPI0309981B1 (pt) 2002-05-14 2019-10-01 Purac Biochem B.V. Método para a produção de ácido láctico ou um sal do mesmo por sacarificação e fermentação simultâneas de amido
AU2003243366B2 (en) 2002-05-30 2008-01-24 Natureworks Llc Methods and materials for the production of lactic acid in yeast
BE1015060A3 (fr) 2002-08-06 2004-09-07 Brussels Biotech Nv Sa Procede de production de polylactide au depart d'une solution d'acide lactique ou d'un de ses derives.
EP1437415A1 (de) 2003-01-13 2004-07-14 PURAC Biochem BV Herstellung von Milchsäure aus einem pentose-enthaltenden Substrat
US7405068B2 (en) 2003-05-02 2008-07-29 Tate & Lyle Ingredients Americas, Inc. Pyruvate producing yeast strain
ES2543385T3 (es) 2003-05-02 2015-08-18 Cargill, Incorporated Especies de levadura genéticamente modificadas y procesos de fermentación que emplean levaduras genéticamente modificadas
CN1795270B (zh) 2003-05-22 2011-09-21 丰田自动车株式会社 编码具有d-乳酸脱氢酶活性蛋白质的dna及其用途
BRPI0414673B1 (pt) 2003-09-30 2019-12-17 Mitsui Chemicals Inc escherichia coli recombinante, bem como método para a produção de ácido d-láctico
US20050112737A1 (en) 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
KR100517065B1 (ko) 2003-12-11 2005-09-26 씨제이 주식회사 고농도 고수율의 젖산을 생산하는 젖산균과 이를 이용한 젖산 생산방법
JP4494399B2 (ja) 2004-03-31 2010-06-30 三菱化学フーズ株式会社 Ｌ‐乳酸の製造方法
WO2005123647A1 (en) 2004-06-17 2005-12-29 Purac Biochem B.V. Process for the preparation of lactic acid or lactate from a magnesium lactate comprising medium

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US7049108B2 (en) 2006-05-23
ATE311460T1 (de) 2005-12-15
IT1294728B1 (it) 1999-04-12
DE69832624T2 (de) 2006-06-08
EP1012298B1 (de) 2005-11-30
ITMI972080A1 (it) 1999-03-12
US6429006B1 (en) 2002-08-06
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CA2302434A1 (en) 1999-03-25
BR9812434A (pt) 2000-09-26
AU748462B2 (en) 2002-06-06
JP2001516584A (ja) 2001-10-02
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US7326550B2 (en) 2008-02-05
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