BR9808928A - Complexo molecular e liberação controlada dealfa hidroxiácidos - Google Patents

Complexo molecular e liberação controlada dealfa hidroxiácidos

Info

Publication number
BR9808928A
BR9808928A BR9808928-5A BR9808928A BR9808928A BR 9808928 A BR9808928 A BR 9808928A BR 9808928 A BR9808928 A BR 9808928A BR 9808928 A BR9808928 A BR 9808928A
Authority
BR
Brazil
Prior art keywords
groups
molecular complex
alpha hydroxy
acid
controlled release
Prior art date
Application number
BR9808928-5A
Other languages
English (en)
Inventor
Ruey J Yu
Eugene J Van Scott
Original Assignee
Ruey J Yu
Eugene J Van Scott
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ruey J Yu, Eugene J Van Scott filed Critical Ruey J Yu
Publication of BR9808928A publication Critical patent/BR9808928A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Patente de Invenção: "COMPLEXO MOLECULAR E LIBERAçãOCONTROLADA DE ALFA HIDROXIáCIDOS". Composiçõescompreendendo um alfa hidroxiácido ou um ácido correlato e umagente de complexação orgânico, tendo um peso molecularvariando de preferência entre cerca de 100 e cerca de 600,podem formar um complexo molecular de liberação controlada. Talagente de complexação de preferência possui um ou mais gruposamino além de outros grupo com elétrons não-partilhados, taiscomo grupos hidroxila, carbonila, amido, éster e alcoxila na mesmamolécula. Tais grupos funcionais são capazes de formar múltiplasligações de hidrogênio intermoleculares com os grupos hidroxila deum alfa hidroxiácido livre ou um ácido correlato. Os agentes decomplexação incluem ésteres de amino ácido, amidas de aminoácido não-nanfotéricas, aminossacarídeos, aminoditóis eaminociclitóis.
BR9808928-5A 1997-04-16 1998-04-10 Complexo molecular e liberação controlada dealfa hidroxiácidos BR9808928A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/842,603 US5877212A (en) 1997-04-16 1997-04-16 Molecular complex and control-release of alpha hydroxyacids
PCT/US1998/007073 WO1998046217A1 (en) 1997-04-16 1998-04-10 Molecular complex and control-release of alpha hydroxyacids

Publications (1)

Publication Number Publication Date
BR9808928A true BR9808928A (pt) 2001-12-04

Family

ID=25287776

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808928-5A BR9808928A (pt) 1997-04-16 1998-04-10 Complexo molecular e liberação controlada dealfa hidroxiácidos

Country Status (7)

Country Link
US (1) US5877212A (pt)
EP (1) EP1009398A4 (pt)
JP (1) JP2001520652A (pt)
AU (1) AU734741B2 (pt)
BR (1) BR9808928A (pt)
CA (1) CA2286730A1 (pt)
WO (1) WO1998046217A1 (pt)

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US6037481A (en) * 1997-08-08 2000-03-14 Industria E Comercio De Cosmeticos Natura Ltda Process for stabilizing levogyre ascorbic acid (LAA), a stable aqueous LAA composition, a process for preparing a stable topical solution, an emulsion, a vitamin product, and a method for cosmetic, pharmaceutical or nutritional treatment
US5958976A (en) * 1997-09-19 1999-09-28 E-L Management Corp. Composition and method for reducing stinging in skin
DE19857151A1 (de) * 1998-12-11 2000-06-15 Degussa Chlorhexidin-Formulierungen, neue Chlorhexidinsalze, sie enthaltende Lösungen und deren Verwendung
AUPP784998A0 (en) * 1998-12-21 1999-01-21 Ghadiminejad, Iraj A low molecular weigh, non-proteinaceous compound that inhibits mitogen induced cytokine production
US6482401B1 (en) * 1998-12-23 2002-11-19 Naturopathic Laboratories International, Inc. Composition for the relief of joint pain and myofascial pain and method of preparing same
EP1685843A1 (en) * 1999-06-30 2006-08-02 Ruey J. Dr. Yu Oligosaccharide aldonic acids and their topical use
US7452545B2 (en) * 2001-11-13 2008-11-18 Yu Ruey J Oligosaccharide aldonic acids and their topical use
US6335023B1 (en) * 1999-06-30 2002-01-01 Ruey J. Yu Oligosaccharide aldonic acids and their topical use
WO2001001993A1 (en) * 1999-07-02 2001-01-11 Greither, Peter A formulation of glucosamine sulphate
US20020182237A1 (en) * 2001-03-22 2002-12-05 The Procter & Gamble Company Skin care compositions containing a sugar amine
AU2002314847A1 (en) 2001-05-31 2002-12-09 Upsher-Smith Laboratories, Inc. Dermatological compositions and methods comprising alpha-hydroxy acids or derivatives
AU2002326756A1 (en) * 2001-08-24 2003-03-10 Vadim Ivanov Ascorbic acid derivatives with amino acids
US7309498B2 (en) * 2001-10-10 2007-12-18 Belenkaya Bronislava G Biodegradable absorbents and methods of preparation
US20050148545A1 (en) * 2001-12-07 2005-07-07 Fosdick Lawrence E. Glucosamine organic acid adducts
EP1492486A2 (en) * 2002-04-10 2005-01-05 Ruey J. Dr. Yu Urea compositions
US20040214215A1 (en) * 2003-03-07 2004-10-28 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
US20040220264A1 (en) * 2003-03-17 2004-11-04 Yu Ruey J Bioavailability and improved delivery of acidic pharmaceutical drugs
US20040220259A1 (en) * 2003-04-04 2004-11-04 Yu Ruey J. Topical treatment of dermatological disorders associated with reactive or dilated blood vessels
US20050196418A1 (en) * 2004-03-04 2005-09-08 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
US7754875B1 (en) * 2004-09-17 2010-07-13 Jfc Technologies, Llc Halide-free glucosamine base-organic acid salt compositions
CN101048139A (zh) * 2004-10-28 2007-10-03 艾德克斯实验室公司 药物活性化合物的控释组合物
US7754679B2 (en) * 2005-11-16 2010-07-13 Idexx Laboratories, Inc. Pharmaceutical compositions for the administration of aptamers
US8114440B2 (en) * 2005-11-16 2012-02-14 Idexx Laboratories Inc. Pharmaceutical compositions for the administration of aptamers
JP5024855B2 (ja) * 2006-05-01 2012-09-12 旭化成ケミカルズ株式会社 グリコール酸とアンモニアからなる新規結晶並びにその製造方法
JP4906395B2 (ja) * 2006-05-01 2012-03-28 旭化成ケミカルズ株式会社 高純度グリコール酸水溶液の製造法
US7723387B2 (en) * 2006-06-28 2010-05-25 Polymer Surfaces Group, Llc Self-neutralizing acid peel for dermatologic use
EP1977743B1 (en) * 2007-03-20 2009-09-02 Johnson & Johnson Consumer France SAS Compositions containing retinoid and beta-aminoisobutyric acid derivates
US8828960B2 (en) * 2007-07-17 2014-09-09 Idexx Laboratories, Inc. Amino acid vitamin ester compositions for controlled delivery of pharmaceutically active compounds
IT1403257B1 (it) * 2010-12-06 2013-10-17 Intercos Italiana Composizioni cosmetiche contenenti composti con azione anti-glicazione, da usare per prevenire e rallentare il processo di invecchiamento cutaneo
CN106432014B (zh) * 2016-09-05 2019-08-16 中国医学科学院放射医学研究所 胺基硫醇类化合物及其制备方法和其在辐射防护中的应用
KR102259668B1 (ko) * 2021-03-31 2021-06-01 신승연 프로테오글리칸-함유 크림 화장료 조성물 및 그의 제조방법
EP4245293A1 (en) * 2022-03-15 2023-09-20 Clariant International Ltd Use of sugar amines as complexing agents
CN115869294B (zh) * 2022-10-25 2023-10-20 广东药科大学 托品酸及其衍生物在制备治疗银屑病药物中的用途

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Also Published As

Publication number Publication date
EP1009398A1 (en) 2000-06-21
CA2286730A1 (en) 1998-10-22
WO1998046217A1 (en) 1998-10-22
AU734741B2 (en) 2001-06-21
US5877212A (en) 1999-03-02
EP1009398A4 (en) 2004-06-23
AU6893998A (en) 1998-11-11
JP2001520652A (ja) 2001-10-30

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1908 DE 31/07/2007.