BR9808472A - Método de produção de proteìna heteróloga - Google Patents
Método de produção de proteìna heterólogaInfo
- Publication number
- BR9808472A BR9808472A BR9808472-0A BR9808472A BR9808472A BR 9808472 A BR9808472 A BR 9808472A BR 9808472 A BR9808472 A BR 9808472A BR 9808472 A BR9808472 A BR 9808472A
- Authority
- BR
- Brazil
- Prior art keywords
- heterologous protein
- production
- protein
- host
- producing
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 10
- 102000004169 proteins and genes Human genes 0.000 title abstract 9
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 238000011031 large-scale manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Patente de Invenção:<B>" MéTODO DE PRODUçãO DE PROTEìNA HETERóLOGA"<D>. Um método de produção de uma proteína heteróloga, compreendendo o cultivo de um hospedeiro produtor de proteína heteróloga, preparado por manipulação de genes, em um meio contendo um ácido graxo, um ou sal do mesmo, e um tensoativo, e a coleta da proteína heteróloga da cultura. A quantidade de produção da proteína heteróloga, produzida por um hospedeiro produtor de proteína heteróloga, pode ser aumentada. Ademais visto que a decomposição da proteína heteróloga por uma enzima derivada do hospedeiro pode ser inibida, permite-se a produção em grande escala de uma proteína heteróloga.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8506497 | 1997-04-03 | ||
PCT/JP1998/001552 WO1998044146A1 (fr) | 1997-04-03 | 1998-04-03 | Procede de production de proteines etrangeres |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9808472A true BR9808472A (pt) | 2000-05-23 |
Family
ID=13848211
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9808472-0A BR9808472A (pt) | 1997-04-03 | 1998-04-03 | Método de produção de proteìna heteróloga |
Country Status (13)
Country | Link |
---|---|
US (1) | US6309864B1 (pt) |
EP (1) | EP1004673B1 (pt) |
KR (1) | KR100389729B1 (pt) |
CN (1) | CN1257549A (pt) |
AT (1) | ATE312195T1 (pt) |
AU (1) | AU746670B2 (pt) |
BR (1) | BR9808472A (pt) |
CA (1) | CA2286395C (pt) |
DE (1) | DE69832709T2 (pt) |
ES (1) | ES2255154T3 (pt) |
NO (1) | NO994788L (pt) |
PL (1) | PL335975A1 (pt) |
WO (1) | WO1998044146A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1198701A (en) * | 1999-10-13 | 2001-04-23 | Lexicon Genetics Incorporated | Novel human membrane proteins |
JP6909591B2 (ja) * | 2017-03-01 | 2021-07-28 | 三洋化成工業株式会社 | 有用物質の生産方法 |
JP2018143238A (ja) * | 2017-03-01 | 2018-09-20 | 三洋化成工業株式会社 | 有用物質の生産方法 |
JP7141227B2 (ja) | 2018-03-27 | 2022-09-22 | 三洋化成工業株式会社 | 有用物質の生産方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60196185A (ja) * | 1984-03-19 | 1985-10-04 | Chemo Sero Therapeut Res Inst | 形質転換酵母の培養方法 |
US5024947A (en) * | 1987-07-24 | 1991-06-18 | Cetus Corporation | Serum free media for the growth on insect cells and expression of products thereby |
ATE112308T1 (de) * | 1987-10-13 | 1994-10-15 | Thomae Gmbh Dr K | Verfahren zur herstellung von proteinen. |
GB8820951D0 (en) * | 1988-09-07 | 1988-10-05 | Delta Biotechnology Ltd | Fermentation method |
ATE135397T1 (de) * | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
US5378612A (en) * | 1990-05-11 | 1995-01-03 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Culture medium for production of recombinant protein |
JPH0714342B2 (ja) * | 1990-08-10 | 1995-02-22 | 田辺製薬株式会社 | エステラーゼの製法 |
JPH0671432B2 (ja) * | 1991-03-20 | 1994-09-14 | 株式会社ミドリ十字 | ヒト血清アルブミンの製造方法 |
JPH0823995A (ja) * | 1994-07-14 | 1996-01-30 | Green Cross Corp:The | 宿主細胞由来のプロテアーゼで低分子化され得る蛋白質の製造方法 |
-
1998
- 1998-04-03 EP EP98911202A patent/EP1004673B1/en not_active Expired - Lifetime
- 1998-04-03 KR KR10-1999-7009057A patent/KR100389729B1/ko not_active IP Right Cessation
- 1998-04-03 AU AU65228/98A patent/AU746670B2/en not_active Ceased
- 1998-04-03 AT AT98911202T patent/ATE312195T1/de not_active IP Right Cessation
- 1998-04-03 CA CA002286395A patent/CA2286395C/en not_active Expired - Fee Related
- 1998-04-03 US US09/402,162 patent/US6309864B1/en not_active Expired - Lifetime
- 1998-04-03 ES ES98911202T patent/ES2255154T3/es not_active Expired - Lifetime
- 1998-04-03 WO PCT/JP1998/001552 patent/WO1998044146A1/ja active IP Right Grant
- 1998-04-03 BR BR9808472-0A patent/BR9808472A/pt not_active IP Right Cessation
- 1998-04-03 CN CN98805410A patent/CN1257549A/zh active Pending
- 1998-04-03 DE DE69832709T patent/DE69832709T2/de not_active Expired - Lifetime
- 1998-04-03 PL PL98335975A patent/PL335975A1/xx unknown
-
1999
- 1999-10-01 NO NO994788A patent/NO994788L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ATE312195T1 (de) | 2005-12-15 |
EP1004673A1 (en) | 2000-05-31 |
EP1004673A4 (en) | 2003-01-15 |
ES2255154T3 (es) | 2006-06-16 |
AU746670B2 (en) | 2002-05-02 |
NO994788L (no) | 1999-12-02 |
US6309864B1 (en) | 2001-10-30 |
KR100389729B1 (ko) | 2003-07-02 |
WO1998044146A1 (fr) | 1998-10-08 |
DE69832709T2 (de) | 2006-07-06 |
KR20010005979A (ko) | 2001-01-15 |
CN1257549A (zh) | 2000-06-21 |
EP1004673B1 (en) | 2005-12-07 |
CA2286395C (en) | 2009-06-23 |
AU6522898A (en) | 1998-10-22 |
CA2286395A1 (en) | 1998-10-08 |
PL335975A1 (en) | 2000-06-05 |
DE69832709D1 (de) | 2006-01-12 |
NO994788D0 (no) | 1999-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TC | Change of name | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7O, 8O, E 9O ANUIDADES |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007. |