BR9808430A - Método para melhorar a especificidade da regulação de gens em um organismo transformado - Google Patents
Método para melhorar a especificidade da regulação de gens em um organismo transformadoInfo
- Publication number
- BR9808430A BR9808430A BR9808430-5A BR9808430A BR9808430A BR 9808430 A BR9808430 A BR 9808430A BR 9808430 A BR9808430 A BR 9808430A BR 9808430 A BR9808430 A BR 9808430A
- Authority
- BR
- Brazil
- Prior art keywords
- specificity
- improve
- promoter
- transformed organism
- gene regulation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8287—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for fertility modification, e.g. apomixis
- C12N15/8289—Male sterility
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8285—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
"MéTODO PARA MELHORAR A ESPECIFICIDADE DA REGULAçãO DE GENS EM UM ORGANISMO TRANSFORMADO". A invenção tem por objetivo melhorar a especificidade da expressão gênica, visando um local de expressão específico de um gen-alvo. Para tanto, é provido um gen quimérico compreendendo um promotor que se expressa em mais de uma região do organismo a ser afetado. o promotor é ligado a um agente que ageta o funcionamento de um gen endógeno na planta que também se expressa em mais de uma região na planta. O promotor e o agente são selecionados de modo a existir uma sobreposição nos seus locais de expressão em mais de uma localidade desejada. Este(s) local (locais) de sobreposição fornecem maior especificidade e obtenção da desejada expressão gênica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9706381.2A GB9706381D0 (en) | 1997-03-27 | 1997-03-27 | Improvements relating to the specificity of gene expression |
PCT/GB1998/000939 WO1998044138A1 (en) | 1997-03-27 | 1998-03-27 | Improvements relating to the specificity of gene expression |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9808430A true BR9808430A (pt) | 2000-05-23 |
BR9808430B1 BR9808430B1 (pt) | 2010-10-19 |
Family
ID=10809964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9808430-5A BR9808430B1 (pt) | 1997-03-27 | 1998-03-27 | método para melhorar a especificidade da regulação de gens em uma planta transformada e constructo. |
Country Status (17)
Country | Link |
---|---|
US (1) | US6140554A (pt) |
EP (1) | EP0977877B1 (pt) |
JP (3) | JP2001517076A (pt) |
CN (1) | CN1161474C (pt) |
AR (1) | AR010410A1 (pt) |
AT (1) | ATE327337T1 (pt) |
AU (1) | AU750951B2 (pt) |
BR (1) | BR9808430B1 (pt) |
CA (1) | CA2285221C (pt) |
DE (1) | DE69834637T2 (pt) |
DK (1) | DK0977877T3 (pt) |
ES (1) | ES2265660T3 (pt) |
GB (1) | GB9706381D0 (pt) |
HK (1) | HK1025792A1 (pt) |
NZ (1) | NZ337646A (pt) |
WO (1) | WO1998044138A1 (pt) |
ZA (1) | ZA982568B (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI9908967B1 (pt) | 1998-03-20 | 2017-05-30 | Benitec Australia Ltd | processos para reprimir, retardar ou de outro modo reduzir a expressão de um gene alvo em uma célula de planta |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
CA2361201A1 (en) | 1999-01-28 | 2000-08-03 | Medical College Of Georgia Research Institute, Inc. | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna |
FR2794772B1 (fr) * | 1999-06-10 | 2001-09-21 | Agronomique Inst Nat Rech | Promoteur permettant l'expression de transgenes dans toute la plante hormis dans la graine |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
WO2002029028A2 (en) * | 2000-10-03 | 2002-04-11 | Bayer Bioscience N.V. | Brassicaceae with altered floral development |
GB0025225D0 (en) * | 2000-10-14 | 2000-11-29 | Cambridge Advanced Tech | Plant cell death system |
NZ526378A (en) * | 2000-11-28 | 2007-12-21 | Du Pont | Nucleic acid fragments encoding floral development proteins in plants and seeds |
US20050066394A1 (en) * | 2000-11-28 | 2005-03-24 | Olga Danilevskaya | Floral development genes |
US20020132257A1 (en) | 2001-01-31 | 2002-09-19 | Tony Giordano | Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell |
DE10325814A1 (de) | 2003-06-06 | 2004-12-23 | Icon Genetics Ag | Sichere Erzeugung eines gewünschten Produkts in hybriden Samen |
US9238818B2 (en) * | 2004-04-20 | 2016-01-19 | Syngenta Participations Ag | Methods and genetic constructs for modification of lignin composition of corn cobs |
CN101914530B (zh) * | 2004-04-20 | 2014-06-04 | 辛根塔参与股份公司 | 用于在植物繁殖组织中表达基因产物的调控序列 |
US8304607B2 (en) * | 2004-04-20 | 2012-11-06 | Syngenta Participations Ag | Epidermal tissue promoter derived from potato for monocots |
GB0421598D0 (en) | 2004-09-29 | 2004-10-27 | Cambridge Advanced Tech | Modification of plant development and morphology |
CN101203611B (zh) | 2005-04-19 | 2013-08-14 | 巴斯福植物科学有限公司 | 控制基因表达的改良方法 |
US20180100162A1 (en) | 2016-10-11 | 2018-04-12 | Dow Agrosciences Llc | Modulation of Transgene Expression in Plants |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8810120D0 (en) * | 1988-04-28 | 1988-06-02 | Plant Genetic Systems Nv | Transgenic nuclear male sterile plants |
WO1991002059A1 (en) * | 1989-08-01 | 1991-02-21 | Pioneer Hi-Bred International, Inc. | Transcriptional activators of anthocyanin biosynthesis as visual markers for plant transformation |
CA2047633A1 (en) * | 1990-09-12 | 1992-03-13 | Ben Bowen | Inactivation of gene transcription in plants using altered transcriptional activators |
US5459252A (en) * | 1991-01-31 | 1995-10-17 | North Carolina State University | Root specific gene promoter |
WO1992021757A1 (en) * | 1991-05-30 | 1992-12-10 | Plant Genetic Systems, N.V. | Nematode-responsive plant promoters |
JPH07500970A (ja) * | 1991-11-20 | 1995-02-02 | シンヘンタ モーヘン ベースローテン フェンノートシャップ | 植物寄生線虫に対する低下された感受性を有する植物の生産方法 |
EP0666922A1 (en) * | 1992-11-02 | 1995-08-16 | Mogen International N.V. | Plants with reduced susceptibility to plant-parasitic nematodes |
ZA939767B (en) * | 1993-01-21 | 1994-09-14 | Univ North Carolina State | Nematode-resistant transgenic plants |
US5534660A (en) * | 1993-04-16 | 1996-07-09 | Dna Plant Technology Corporation | Ph genes and their uses |
US5530191A (en) * | 1994-03-24 | 1996-06-25 | Rutgers, The State University Of New Jersey | Method for producing cytoplasmic male sterility in plants and use thereof in production of hybrid seed |
DE19503359C1 (de) * | 1995-02-02 | 1996-02-22 | Kws Kleinwanzlebener Saatzucht | Streßtolerante Pflanzen und Verfahren zu deren Herstellung |
GB9514437D0 (en) * | 1995-07-14 | 1995-09-13 | Danisco | Inhibition of gene expression |
US5837876A (en) * | 1995-07-28 | 1998-11-17 | North Carolina State University | Root cortex specific gene promoter |
GB9518731D0 (en) * | 1995-09-13 | 1995-11-15 | Innes John Centre | Flowering genes |
AUPN816196A0 (en) * | 1996-02-19 | 1996-03-14 | Forbio Research Pty Ltd | Regulation of eukaryotic gene expression |
-
1997
- 1997-03-27 GB GBGB9706381.2A patent/GB9706381D0/en active Pending
-
1998
- 1998-03-26 ZA ZA9802568A patent/ZA982568B/xx unknown
- 1998-03-27 WO PCT/GB1998/000939 patent/WO1998044138A1/en active IP Right Grant
- 1998-03-27 BR BRPI9808430-5A patent/BR9808430B1/pt not_active IP Right Cessation
- 1998-03-27 DK DK98913933T patent/DK0977877T3/da active
- 1998-03-27 CN CNB988054566A patent/CN1161474C/zh not_active Expired - Fee Related
- 1998-03-27 JP JP51977498A patent/JP2001517076A/ja active Pending
- 1998-03-27 CA CA2285221A patent/CA2285221C/en not_active Expired - Fee Related
- 1998-03-27 AT AT98913933T patent/ATE327337T1/de not_active IP Right Cessation
- 1998-03-27 AU AU68453/98A patent/AU750951B2/en not_active Ceased
- 1998-03-27 US US09/049,475 patent/US6140554A/en not_active Expired - Lifetime
- 1998-03-27 AR ARP980101420A patent/AR010410A1/es active IP Right Grant
- 1998-03-27 DE DE69834637T patent/DE69834637T2/de not_active Revoked
- 1998-03-27 EP EP98913933A patent/EP0977877B1/en not_active Revoked
- 1998-03-27 ES ES98913933T patent/ES2265660T3/es not_active Expired - Lifetime
- 1998-03-27 NZ NZ337646A patent/NZ337646A/en not_active IP Right Cessation
-
2000
- 2000-08-04 HK HK00104887A patent/HK1025792A1/xx not_active IP Right Cessation
-
2009
- 2009-09-14 JP JP2009211993A patent/JP2010029196A/ja not_active Ceased
-
2013
- 2013-11-11 JP JP2013232689A patent/JP2014057593A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU750951B2 (en) | 2002-08-01 |
DE69834637D1 (de) | 2006-06-29 |
CN1161474C (zh) | 2004-08-11 |
ES2265660T3 (es) | 2007-02-16 |
AR010410A1 (es) | 2000-06-07 |
CN1257548A (zh) | 2000-06-21 |
AU6845398A (en) | 1998-10-22 |
JP2010029196A (ja) | 2010-02-12 |
CA2285221A1 (en) | 1998-10-08 |
WO1998044138A1 (en) | 1998-10-08 |
BR9808430B1 (pt) | 2010-10-19 |
HK1025792A1 (en) | 2000-11-24 |
NZ337646A (en) | 2001-06-29 |
DK0977877T3 (da) | 2006-09-25 |
JP2014057593A (ja) | 2014-04-03 |
ZA982568B (en) | 2000-10-23 |
DE69834637T2 (de) | 2006-10-05 |
US6140554A (en) | 2000-10-31 |
CA2285221C (en) | 2010-10-12 |
EP0977877A1 (en) | 2000-02-09 |
EP0977877B1 (en) | 2006-05-24 |
ATE327337T1 (de) | 2006-06-15 |
GB9706381D0 (en) | 1997-05-14 |
JP2001517076A (ja) | 2001-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 19/10/2010, OBSERVADAS AS CONDICOES LEGAIS. |
|
B25A | Requested transfer of rights approved |
Owner name: BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB |
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B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 18A ANUIDADE. |
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B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |