BR9808313A - Métodos para determinar a predisposição de um paciente à doença arterial coronariana e kit para previsão de doença arterial coronariana - Google Patents

Métodos para determinar a predisposição de um paciente à doença arterial coronariana e kit para previsão de doença arterial coronariana

Info

Publication number
BR9808313A
BR9808313A BR9808313-9A BR9808313A BR9808313A BR 9808313 A BR9808313 A BR 9808313A BR 9808313 A BR9808313 A BR 9808313A BR 9808313 A BR9808313 A BR 9808313A
Authority
BR
Brazil
Prior art keywords
coronary artery
artery disease
methods
patient
determining
Prior art date
Application number
BR9808313-9A
Other languages
English (en)
Inventor
Sheila E Francis
David C Crossman
Gordon W Duff
Original Assignee
Medical Science Sys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Science Sys Inc filed Critical Medical Science Sys Inc
Publication of BR9808313A publication Critical patent/BR9808313A/pt

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

<B>"MéTODOS PARA DETERMINAR A PREDISPOSIçãO DE UM PACIENTE à DOENçA ARTERIAL CORONARIANA E KIT PARA PREVISãO DE DOENçA ARTERIAL CORONARIANA''<D>. Revela-se métodos e análises para previsão de risco em pacientes quanto a um distúrbio inflamatório tal como doença arterial coronariana ou distúrbios vasculares relacionados. Os métodos compreendem a obtenção de uma amostra biológica de um paciente e a determinação da presença ou da ausência de um determinado alelo o qual é ligado a doenças arteriais coronarianas. A detecção do alelo indica a suscetabilidade ao desenvolvimento de doença arterial coronariana. Kits para a detecção de doença arterial coronariana são também providos, bem como meios para identificação de outros alelos associados com doenças arteriais coronarianas.
BR9808313-9A 1997-03-10 1998-03-09 Métodos para determinar a predisposição de um paciente à doença arterial coronariana e kit para previsão de doença arterial coronariana BR9808313A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/813,456 US6210877B1 (en) 1997-03-10 1997-03-10 Prediction of coronary artery disease
PCT/US1998/004725 WO1998040517A1 (en) 1997-03-10 1998-03-09 Prediction of coronary artery disease

Publications (1)

Publication Number Publication Date
BR9808313A true BR9808313A (pt) 2000-05-16

Family

ID=25212420

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808313-9A BR9808313A (pt) 1997-03-10 1998-03-09 Métodos para determinar a predisposição de um paciente à doença arterial coronariana e kit para previsão de doença arterial coronariana

Country Status (22)

Country Link
US (1) US6210877B1 (pt)
EP (1) EP0983381B1 (pt)
JP (2) JP4250765B2 (pt)
CN (1) CN100523214C (pt)
AR (1) AR011943A1 (pt)
AT (1) ATE370246T1 (pt)
AU (1) AU738875B2 (pt)
BR (1) BR9808313A (pt)
CA (1) CA2282746C (pt)
DE (2) DE69838250T2 (pt)
DK (1) DK0983381T3 (pt)
EA (1) EA199900813A1 (pt)
ES (1) ES2156843T3 (pt)
GR (1) GR20010300016T1 (pt)
IL (1) IL131745A0 (pt)
MX (1) MXPA99008223A (pt)
NO (1) NO994365L (pt)
NZ (1) NZ337642A (pt)
PL (1) PL335603A1 (pt)
PT (1) PT983381E (pt)
WO (1) WO1998040517A1 (pt)
ZA (1) ZA981937B (pt)

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US7820383B2 (en) * 1997-03-10 2010-10-26 Interleukin Genetics, Inc. Method for diagnosing myocardial infarction
US6720141B1 (en) 1999-11-01 2004-04-13 Interleukin Genetics, Inc. Diagnostics and therapeutics for restenosis
US6210877B1 (en) * 1997-03-10 2001-04-03 Interleukin Genetics, Inc. Prediction of coronary artery disease
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
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GB9723835D0 (en) * 1997-11-13 1998-01-07 Nicklin Martin Interleukin knockout
US6437216B1 (en) 1997-11-13 2002-08-20 Interleukin Genetics Inc. Transgenic models of inflammatory disease
US6746839B1 (en) * 1998-01-12 2004-06-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for an obstructive airway disease
US20050032077A1 (en) * 1998-03-10 2005-02-10 Duff Gordon W. Detecting genetic predisposition to sight-threatening diabetic retinopathy
IL139131A0 (en) * 1998-04-21 2001-11-25 Interleukin Genetics Inc Fetal testing for prediction of low birth weight
US6733967B1 (en) 1998-04-21 2004-05-11 Interleukin Genetics, Inc. Fetal testing for prediction of low birth weight
US6251598B1 (en) * 1998-10-30 2001-06-26 Interleukin Genetics, Inc. Methods for diagnosing sepsis
JP2003500005A (ja) * 1999-02-10 2003-01-07 インターリューキン ジェネティックス インコーポレイテッド ＩＬ−１β遺伝子の突然変異に基づく治療および診断
DE60039760D1 (de) * 1999-05-24 2008-09-18 Interleukin Genetics Inc Diagnose von Restenose
AU784224B2 (en) * 1999-06-30 2006-02-23 Interleukin Genetics, Inc. Diagnostics and therapeutics for diseases associated with an IL-1 inflammatory haplotype
KR20040026665A (ko) * 2001-06-15 2004-03-31 인터레우킨 제네틱스, 인코포레이티드 노화 관련 증상의 조기 개시를 검출 및 치료하는 방법
US20080311581A1 (en) * 2001-11-19 2008-12-18 David Wyllie Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases
WO2003044176A2 (en) 2001-11-19 2003-05-30 Interleukin Genetics, Inc. Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases
EP1327639A1 (en) * 2002-01-15 2003-07-16 Bayer Ag Prediction of cardiovascular disease by genetic polymorphisms in cardiovascular associated genes
US20070264645A1 (en) * 2002-01-25 2007-11-15 Kenneth Kornman IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
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CA2668722A1 (en) * 2006-11-15 2008-05-22 Interleukin Genetics, Inc. The il-1 gene cluster, insulin resistance and coronary artery disease associated polymorphisms and haplotypes and methods of using same
CA2705142A1 (en) * 2007-11-08 2009-05-14 Interleukin Genetics, Inc. Diagnostics for aging-related dermatologic disorders
US20100112570A1 (en) * 2008-10-22 2010-05-06 Interleukin Genetics, Inc. Genetic Markers for Weight Management and Methods of Use Thereof
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Also Published As

Publication number Publication date
CA2282746A1 (en) 1998-09-17
WO1998040517A1 (en) 1998-09-17
ES2156843T3 (es) 2008-04-16
DE69838250T2 (de) 2008-05-08
NZ337642A (en) 2001-02-23
MXPA99008223A (es) 2003-07-21
DE983381T1 (de) 2000-11-09
EA199900813A1 (ru) 2000-06-26
CN1255948A (zh) 2000-06-07
EP0983381A1 (en) 2000-03-08
GR20010300016T1 (en) 2001-04-30
JP2001514522A (ja) 2001-09-11
JP2009077727A (ja) 2009-04-16
PL335603A1 (en) 2000-05-08
NO994365L (no) 1999-11-09
US6210877B1 (en) 2001-04-03
CN100523214C (zh) 2009-08-05
EP0983381A4 (en) 2004-05-12
AU738875B2 (en) 2001-09-27
DE69838250D1 (de) 2007-09-27
DK0983381T3 (da) 2007-12-17
CA2282746C (en) 2009-02-24
ATE370246T1 (de) 2007-09-15
ZA981937B (en) 1999-09-06
JP4250765B2 (ja) 2009-04-08
ES2156843T1 (es) 2001-08-01
PT983381E (pt) 2007-11-26
EP0983381B1 (en) 2007-08-15
AU6457498A (en) 1998-09-29
IL131745A0 (en) 2001-03-19
NO994365D0 (no) 1999-09-09
AR011943A1 (es) 2000-09-13

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Legal Events

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FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]