BR9804768A - Droga e aplicação de uma mistura - Google Patents

Droga e aplicação de uma mistura

Info

Publication number
BR9804768A
BR9804768A BR9804768-0A BR9804768A BR9804768A BR 9804768 A BR9804768 A BR 9804768A BR 9804768 A BR9804768 A BR 9804768A BR 9804768 A BR9804768 A BR 9804768A
Authority
BR
Brazil
Prior art keywords
mixture
drug
application
local anesthetic
anesthetic
Prior art date
Application number
BR9804768-0A
Other languages
English (en)
Inventor
Carsten Weber
Ralf Oettmeier
Uwe Reuter
Original Assignee
Medicur Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicur Pharma Gmbh filed Critical Medicur Pharma Gmbh
Publication of BR9804768A publication Critical patent/BR9804768A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"DROGA E APLICAçãO DE UMA MISTURA". A invenção está direcionada a uma droga que é preferivelmente usável para inibir inflamação em processos inflamatórios crónicos e autoimunes e/ou produz efeitos vasodilatadores e simpaticolíticos. De acordo com a invenção, o objeto da invenção é alcançado através de uma mistura contendo um anestésico local do tipo éster ou do tipo amida, preferivelmente hidrocloreto de procaína, água, e pelo menos uma substância para ajustar o pH da mistura na faixa de 7,6 a 8,6. é possível por meio desta droga aumentar significativamente a quantidade injetável de anestésico comparado com drogas comercialmente disponíveis e conhecidas contendo um anestésico local como ingrediente ativo. A mistura pode ser aplicada continuamente por infusão subcutânea ou endovenosa.
BR9804768-0A 1997-03-29 1998-03-25 Droga e aplicação de uma mistura BR9804768A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19713263A DE19713263C2 (de) 1997-03-29 1997-03-29 Verwendung einer Procainhydrochlorid-Injektionslösung zur Entzündungshemmung
PCT/EP1998/001742 WO1998043633A1 (de) 1997-03-29 1998-03-25 Lokalanästhetikum enthaltende gepufferte zusammensetzungen zur entzündungshemmung

Publications (1)

Publication Number Publication Date
BR9804768A true BR9804768A (pt) 2000-01-25

Family

ID=7825026

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9804768-0A BR9804768A (pt) 1997-03-29 1998-03-25 Droga e aplicação de uma mistura

Country Status (12)

Country Link
US (1) US6194456B1 (pt)
EP (1) EP0910364A1 (pt)
JP (1) JP2000512659A (pt)
AU (1) AU6730798A (pt)
BR (1) BR9804768A (pt)
CA (1) CA2250106A1 (pt)
CZ (1) CZ389498A3 (pt)
DE (1) DE19713263C2 (pt)
EA (1) EA199801035A1 (pt)
IL (1) IL126671A0 (pt)
PL (1) PL330036A1 (pt)
WO (1) WO1998043633A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6551857B2 (en) * 1997-04-04 2003-04-22 Elm Technology Corporation Three dimensional structure integrated circuits
DE10039449A1 (de) * 2000-08-11 2003-07-24 Id Pharma Gmbh I Ins Verwendung einer lokalanästhetikumhaltigen Zusammensetzung zur Behandlung von Hyperalgesien
US20050084508A1 (en) * 2003-07-22 2005-04-21 Vancaillie Thierry G. Topical anesthesia formulation for bodily cavities
DE102004035808A1 (de) * 2004-07-21 2006-03-16 Kasch, Helmut, Dr. Ammoniumsalze und Ammoniumsalz-Mineralsalzchlatrate als Transport- und Wirkform für pharmazeutische-medizinische und als Phasentransfermittel für chemische Anwendungen
US20080045925A1 (en) * 2006-06-19 2008-02-21 Stepovich Matthew J Drug delivery system
US20080086108A1 (en) * 2006-10-05 2008-04-10 Falkel Michael I Method and apparatus for delivering a drug

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748022A (en) 1985-03-25 1988-05-31 Busciglio John A Topical composition
US4938970A (en) * 1987-02-06 1990-07-03 Hustead Robert E Painless electrolyte solutions
US5209724A (en) 1988-04-11 1993-05-11 Dhaliwal Avtar S Composite anesthetic article and method of use
US5149320A (en) * 1988-04-11 1992-09-22 Dhaliwal Avtar S Composite anesthetic article and method of use
US5064858A (en) * 1988-08-17 1991-11-12 Spectrum Pharmaceutical Corporation Protected complex of procaine for the treatment of symptoms from narcotics addiction, tinnitus and Alzheimer's disease
GB9101986D0 (en) 1991-01-30 1991-03-13 Smith & Nephew Pharmaceutical compositions
FR2704429B3 (fr) 1993-04-30 1995-07-13 Algovital Sarl Formulation associant une réaction alcaline et des composants d'huiles essentielles pour réaliser une anesthésie locale, par voie externe, transcutanée, sans injection.
US5505922A (en) * 1993-08-13 1996-04-09 University Of Maryland At Baltimore Anesthetic pharmaceutical combination

Also Published As

Publication number Publication date
DE19713263C2 (de) 1999-11-04
PL330036A1 (en) 1999-04-26
JP2000512659A (ja) 2000-09-26
CA2250106A1 (en) 1998-09-29
CZ389498A3 (cs) 1999-04-14
US6194456B1 (en) 2001-02-27
EP0910364A1 (de) 1999-04-28
EA199801035A1 (ru) 1999-06-24
IL126671A0 (en) 1999-08-17
DE19713263A1 (de) 1998-10-01
WO1998043633A1 (de) 1998-10-08
AU6730798A (en) 1998-10-22

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 36 DA LPI .