KR920017668A - 암 전이 억제 또는 예방 방법 및 이를 위한 제제 - Google Patents
암 전이 억제 또는 예방 방법 및 이를 위한 제제 Download PDFInfo
- Publication number
- KR920017668A KR920017668A KR1019920003685A KR920003685A KR920017668A KR 920017668 A KR920017668 A KR 920017668A KR 1019920003685 A KR1019920003685 A KR 1019920003685A KR 920003685 A KR920003685 A KR 920003685A KR 920017668 A KR920017668 A KR 920017668A
- Authority
- KR
- South Korea
- Prior art keywords
- inhibiting
- mammal
- hirudin
- methods
- cancer metastasis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (8)
- 종양 전이의 억제 또는 예방용 약제학적 조성물을 제조하기 위한 히루딘의 용도.
- 제1항에 있어서, 히루딘이 데설파토히루딘 변이체 또는 이의 돌연변이체의 용도.
- 제1항 또는 2항에 있어서, 히루딘이 데설파토히루딘 HV1인 용도.
- 제1항 내지 3항중 어느 한 항에 있어서, 약제학적 조성물이 비경구 투여를 위한 용도.
- 제1항 내지 4항중 어느 한 항에 있어서, 약제학적 조성물이 포유동물에 투여하기 위한 용도.
- 제5항에 있어서, 포유 동물이 사람인 용도.
- 포유 동물에 유효량의 히루딘을 투여함을 특징으로하여, 포유 동물에서 종앙 전이를 억제하거나 예방하는 방법.
- 포유 동물에서 종양 전이를 억제하거나 예방하기 위한 히루딘을 함유하는 약제학적 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66654091A | 1991-03-08 | 1991-03-08 | |
US07/666,540 | 1991-03-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR920017668A true KR920017668A (ko) | 1992-10-21 |
Family
ID=24674487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019920003685A KR920017668A (ko) | 1991-03-08 | 1992-03-06 | 암 전이 억제 또는 예방 방법 및 이를 위한 제제 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0503829A3 (ko) |
JP (1) | JPH04327539A (ko) |
KR (1) | KR920017668A (ko) |
AU (1) | AU659432B2 (ko) |
CA (1) | CA2062388A1 (ko) |
IE (1) | IE920732A1 (ko) |
IL (1) | IL101173A0 (ko) |
NZ (1) | NZ241880A (ko) |
ZA (1) | ZA921689B (ko) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9401448D0 (en) * | 1994-01-26 | 1994-03-23 | Ciba Geigy Ag | Stable dry powders |
GB9401447D0 (en) | 1994-01-26 | 1994-03-23 | Ciba Geigy Ag | Pharmaceutical compositions |
EP0998942A4 (en) * | 1997-01-20 | 2006-08-16 | Japan Energy Corp | METHOD FOR STABILIZING PEPTIDES AND FREEZERED MEDICINAL COMPOSITIONS THEREOF |
DE10162521A1 (de) * | 2001-12-19 | 2003-07-17 | Goetz Nowak | Verwendung von molekulargewichtserweiterten Substanzen in der Tumortherapie |
WO2004026252A2 (en) * | 2002-09-23 | 2004-04-01 | The Regents Of The University Of Michigan | Glioma treatments |
US7795205B2 (en) * | 2004-04-12 | 2010-09-14 | Canyon Pharmaceuticals, Inc. | Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor |
US8357652B2 (en) | 2009-11-20 | 2013-01-22 | Academia Sinica | Anti-tumor fibrillar human serum albumin methods and compositions |
US8685462B1 (en) | 2012-09-17 | 2014-04-01 | Biopep Solutions, Inc. | Whole, leech saliva product and applications thereof |
CN116850272A (zh) * | 2022-03-28 | 2023-10-10 | 珠海天健和睦生物制药有限公司 | 重组水蛭素在制备用于治疗肝癌的药物中的应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4588587A (en) * | 1983-03-01 | 1986-05-13 | Pennsylvania Hospital | Method of treatment to inhibit metastasis |
EP0333356A3 (en) * | 1988-03-04 | 1990-12-19 | Biogen, Inc. | Hirudin peptides |
IL86857A (en) * | 1988-06-24 | 1994-04-12 | Yissum Res Dev Co | Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same |
US5179196A (en) * | 1989-05-04 | 1993-01-12 | Sri International | Purification of proteins employing ctap-iii fusions |
AU6070590A (en) * | 1989-07-20 | 1991-02-22 | Biogen, Inc. | Hirudin peptide derivatives |
US5196404B1 (en) * | 1989-08-18 | 1996-09-10 | Biogen Inc | Inhibitors of thrombin |
DE3939801A1 (de) * | 1989-12-01 | 1991-06-06 | Basf Ag | Neue proteine und ihre herstellung |
US5118790A (en) * | 1990-07-24 | 1992-06-02 | Sri International | Analogs of hirudin |
GB2247239A (en) * | 1990-08-22 | 1992-02-26 | Ciba Geigy Ag | Hirudin conjugates with polyoxyethylene |
-
1992
- 1992-02-20 AU AU11092/92A patent/AU659432B2/en not_active Ceased
- 1992-03-04 EP EP19920301844 patent/EP0503829A3/en not_active Withdrawn
- 1992-03-06 NZ NZ241880A patent/NZ241880A/en unknown
- 1992-03-06 KR KR1019920003685A patent/KR920017668A/ko not_active Application Discontinuation
- 1992-03-06 IL IL101173A patent/IL101173A0/xx unknown
- 1992-03-06 IE IE073292A patent/IE920732A1/en unknown
- 1992-03-06 CA CA002062388A patent/CA2062388A1/en not_active Abandoned
- 1992-03-06 JP JP4049406A patent/JPH04327539A/ja active Pending
- 1992-03-06 ZA ZA921689A patent/ZA921689B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0503829A3 (en) | 1993-06-02 |
AU659432B2 (en) | 1995-05-18 |
NZ241880A (en) | 1997-04-24 |
JPH04327539A (ja) | 1992-11-17 |
AU1109292A (en) | 1992-09-10 |
ZA921689B (en) | 1992-10-28 |
CA2062388A1 (en) | 1992-09-09 |
IE920732A1 (en) | 1992-09-09 |
EP0503829A2 (en) | 1992-09-16 |
IL101173A0 (en) | 1992-11-15 |
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