BR9711448A - Processo para caracterizar microorganismos, aparelho paraa triagem de microorganismos, e, base de dados de microorganismos. - Google Patents

Processo para caracterizar microorganismos, aparelho paraa triagem de microorganismos, e, base de dados de microorganismos.

Info

Publication number
BR9711448A
BR9711448A BR9711448-0A BR9711448A BR9711448A BR 9711448 A BR9711448 A BR 9711448A BR 9711448 A BR9711448 A BR 9711448A BR 9711448 A BR9711448 A BR 9711448A
Authority
BR
Brazil
Prior art keywords
microorganisms
spectral data
database
screening
characterizing
Prior art date
Application number
BR9711448-0A
Other languages
English (en)
Inventor
Martin Arthur Claydon
Simon Nicholas Davey
Valerie Edwards Jones
Derek Boyd Gordon
Original Assignee
Univ Manchester Metropolitan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Manchester Metropolitan filed Critical Univ Manchester Metropolitan
Publication of BR9711448A publication Critical patent/BR9711448A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Optics & Photonics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Lock And Its Accessories (AREA)

Abstract

PROCESSO PARA CARACTERIZAR MICROORGANISMOS E, APARELHO PARA A TRIAGEM DE MICROORGANISMOS". Processo para caracterizar microorganismos Aparelho para a triagem de microorganismos A invenção refere-se a um processo e aparelho para caracterizar microorganismos. A invenção usa dados espectrais de espectrometria de massa de tempo de vóo, de ionização por dessorção a laser, auxiliada por matriz, (MALDI-TOF-MS) para uma faixa de microorganismos conhecidos. Este dado espectral é incluído em uma base de dados para dados espectrais de cada um dos microorganismos conhecidos. Uma amostra de um microorganismo não identificado é preparada e então submetida a análise por técnicas MALDI-TOF-MS para produzir os dados espectrais do organismo desconhecido. Este dado é então comparado; usando meios de comparação apropriados com os dados espectrais na base de dados. A similaridade indica o gênero enquanto a identidade indica o microorganismo específico. O aparelho para esta análise tem a vantagem de que uma vez ajustado e calibrado, ele é relativamente simples de usar.
BR9711448-0A 1996-08-27 1997-08-26 Processo para caracterizar microorganismos, aparelho paraa triagem de microorganismos, e, base de dados de microorganismos. BR9711448A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9617852.0A GB9617852D0 (en) 1996-08-27 1996-08-27 Micro-organism identification
PCT/GB1997/002278 WO1998009314A1 (en) 1996-08-27 1997-08-26 Microorganism identification

Publications (1)

Publication Number Publication Date
BR9711448A true BR9711448A (pt) 2000-01-18

Family

ID=10798972

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9711448-0A BR9711448A (pt) 1996-08-27 1997-08-26 Processo para caracterizar microorganismos, aparelho paraa triagem de microorganismos, e, base de dados de microorganismos.

Country Status (10)

Country Link
EP (1) EP0922295A1 (pt)
JP (1) JP2001502164A (pt)
KR (1) KR20000035935A (pt)
CN (1) CN1234906A (pt)
AU (1) AU4024597A (pt)
BR (1) BR9711448A (pt)
CA (1) CA2264535A1 (pt)
GB (1) GB9617852D0 (pt)
TR (1) TR199900780T2 (pt)
WO (1) WO1998009314A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2335491A (en) * 1998-07-07 1999-09-22 Aromascan Plc Detecting microorganisms
US7020559B1 (en) 1998-11-17 2006-03-28 University Of Maryland Methods for identifying and classifying organisms by mass spectrometry and database searching
CA2298181C (en) 2000-02-02 2006-09-19 Dayan Burke Goodnough Non-targeted complex sample analysis
WO2001094910A2 (de) * 2000-06-07 2001-12-13 Basf Aktiengesellschaft Verfahren zur qualitativen und quantitativen analyse komplexer gemische chemischer verbindungen mit maldi-tof-massenspektrometrie
DE60337003D1 (de) 2002-03-22 2011-06-16 Phenomenome Discoveries Inc Verfahren zur visualisierung von nicht gezielten metabolomischen daten, erzeugt durch ionenzyklotronresonanz -fouriertransformation-massenspektrometer
JP2005522713A (ja) * 2002-04-15 2005-07-28 サーモ フィニガン エルエルシー 生物学的分子の定量
DE10300743A1 (de) 2003-01-07 2004-07-29 AnagnosTec, Gesellschaft für Analytische Biochemie und Diagnostik mbH Verfahren zur Identifizierung von Mikroorganismen mittels Massenspektrometrie
DE102004051043B4 (de) 2004-10-20 2011-06-01 Bruker Daltonik Gmbh Angleichung von Flugzeitmassenspektren
CA2772688A1 (en) 2005-09-12 2007-03-22 Phenomenome Discoveries Inc. Methods for the diagnosis of colorectal cancer and ovarian cancer health states
JP4818981B2 (ja) * 2006-04-28 2011-11-16 独立行政法人産業技術総合研究所 細胞の迅速識別方法及び識別装置
EP1942194A1 (en) 2007-01-08 2008-07-09 Université René Descartes Method for identifying a germ isolated from a clinical sample
EP2060919A1 (en) * 2007-11-13 2009-05-20 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO MALDI matrix and MALDI method
EP2157599A1 (en) * 2008-08-21 2010-02-24 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Method and apparatus for identification of biological material
DE102009007266B4 (de) * 2009-02-03 2012-04-19 Bruker Daltonik Gmbh Massenspektrometrische Identifizierung von Mikroorganismen in komplexen Proben
US20100291618A1 (en) * 2009-05-15 2010-11-18 Biomerieux, Inc. Methods for rapid identification and/or characterization of a microbial agent in a sample
FR2953530A1 (fr) 2009-12-03 2011-06-10 Assist Publ Hopitaux Marseille Procede d'identification rapide des virus par spectrometrie de masse
JP2011147403A (ja) * 2010-01-22 2011-08-04 Hitachi High-Technologies Corp 細菌検査装置及び細菌検査方法
DE102010033105B4 (de) 2010-08-02 2016-05-04 Bruker Daltonik Gmbh Massenspektrometrische Sepsisdiagnose ohne Blutkultur
JP5313218B2 (ja) * 2010-09-30 2013-10-09 株式会社日立ハイテクノロジーズ 細菌検査システム
GB2495899B (en) * 2011-07-04 2018-05-16 Thermo Fisher Scient Bremen Gmbh Identification of samples using a multi pass or multi reflection time of flight mass spectrometer
JP5750676B2 (ja) * 2011-10-18 2015-07-22 株式会社島津製作所 細胞識別装置及びプログラム
US9074236B2 (en) * 2012-05-01 2015-07-07 Oxoid Limited Apparatus and methods for microbial identification by mass spectrometry
CN103308696B (zh) * 2013-05-30 2015-06-24 中国疾病预防控制中心传染病预防控制所 基于质谱技术的布鲁氏菌快速检测试剂盒
DE102013022016B4 (de) 2013-12-20 2015-07-09 Bruker Daltonik Gmbh Mikroben-Identifizierung durch Massenspektrometrie und Infrarot-Spektrometrie
KR20170040078A (ko) 2015-10-02 2017-04-12 숭실대학교산학협력단 식중독균 고속 검출방법
US20170108509A1 (en) * 2015-10-19 2017-04-20 Virgin Instruments Corporation Method For Using Protein Databases To Identify Microorganisms
CN111220686A (zh) * 2018-11-23 2020-06-02 中国科学院大连化学物理研究所 一种基于病毒鉴定的质谱数据库建立方法
KR102028564B1 (ko) * 2018-12-10 2019-10-04 한림대학교 산학협력단 말디-토프 질량분석기를 이용한 메티실린-내성 황색포도구균 균류의 동정방법
CN114184668B (zh) * 2020-09-15 2024-03-26 广州禾信康源医疗科技有限公司 微生物鉴定方法和双极性标准谱图生成方法
CN113219115A (zh) * 2021-05-18 2021-08-06 广东省科学院微生物研究所(广东省微生物分析检测中心) 一种基于maldi-tof ms的蜡样芽胞杆菌和苏云金芽胞杆菌快速鉴定方法

Also Published As

Publication number Publication date
CN1234906A (zh) 1999-11-10
CA2264535A1 (en) 1998-03-05
WO1998009314A1 (en) 1998-03-05
JP2001502164A (ja) 2001-02-20
TR199900780T2 (xx) 1999-07-21
GB9617852D0 (en) 1996-10-09
EP0922295A1 (en) 1999-06-16
AU4024597A (en) 1998-03-19
KR20000035935A (ko) 2000-06-26

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Legal Events

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FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired